Basic Information

Insect: Drosophila ficusphila
Gene Symbol: zfh1
Assembly: GCA_018152265.1
Location: JAECXK010000775.1:27983900-27986431[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 8e-05 0.0057 16.9 2.0 2 23 17 38 16 38 0.97

2 7 3e-06 0.00021 21.4 6.3 1 23 47 69 47 69 0.99

3 7 0.00018 0.013 15.8 1.2 3 21 77 95 75 96 0.94

4 7 0.007 0.49 10.8 1.2 2 21 319 338 318 339 0.92

5 7 2e-05 0.0015 18.8 0.5 1 23 654 676 654 676 0.95

6 7 3e-05 0.0021 18.3 7.4 1 23 682 704 682 704 0.98

7 7 0.0015 0.11 12.9 4.3 1 21 710 730 710 731 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	8e-05	0.0057	16.9	2.0	2	23	17	38	16	38	0.97
2	7	3e-06	0.00021	21.4	6.3	1	23	47	69	47	69	0.99
3	7	0.00018	0.013	15.8	1.2	3	21	77	95	75	96	0.94
4	7	0.007	0.49	10.8	1.2	2	21	319	338	318	339	0.92
5	7	2e-05	0.0015	18.8	0.5	1	23	654	676	654	676	0.95
6	7	3e-05	0.0021	18.3	7.4	1	23	682	704	682	704	0.98
7	7	0.0015	0.11	12.9	4.3	1	21	710	730	710	731	0.96

Sequence Information

Coding Sequence: ATGTCGGCCGCCGCGCTTCTCATCTCTTCTTCTTCCTCATTGGAAAAGACCTGCCGGATTTGCCACAAGGCATTCGCGAATGTCTACCGCCTGCAGAGGCACATGATCAGCCACGACGAGAGCGCGCTCCTGCGGAAGTTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAGTTCAAGCACCACCTCAAGGAGCACGTGAGGATCCATTCCGGCGAGAAACCCTTCGGCTGCGACAACTGCGGCAAGCGGTTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAGCTGAACAACAACCGCGCTCTGCTGAAGAGGCTGGAGAAGAGTCCCGGCTCCGGGTCGGCGGGATCCCGCCGGTCGCCCTCGGATCTCGGAAAGGGAAAAGGGCTGCCGGTTCAGCCCTCGCTGTCCGGACTGCCCAACCCGATGATCTACTTCGCCAGCGACGCCCAGAACCAAGCTGGAAACGCGGGCCCCGCTCCGTTCCCGCCCTTTAACCCCACGAACTACATGAACGCGGCCCTCCTGGCCTTCCCCAACTCCTTCATGGTCGCAGCTGGCCTCGATCCCCGGGTGCATCCCTACAGCATCCAGCGGCTGCTGCACCTCTCGGCCGCCGGCCAGCAGCAGCGGGAGGAGGAGCGGGAGCGGGAGCAGCAGCAGGAGGACGAGGAGACCCCCGACGAGCCCAAGCTGGTGATGGATATCGACGAGCCCGAGGCCAAGGAGCGGGTTCCCACGCCGCCGCCCGCGGAGGAGGCCACGCCCATCAAGCGGGAGGAGAGCAGGGAGGCCTCGCCTGCCCCAGAGGGCTACCCCGCATCCCCTCCAGCGATCAAGCAGGAGCAGGAACCCCTTCCTGCCGTCGAGGAGCCCGAGATCTCCGTCGAAGAGCCACCGCAGGCGGAGCAGCCCGCCGATCTGCGCTGCAGCCGCTGCTCCAAGCAGTTCAACCACCGCACGGAGCTGGTGCAGCACGAGAAGGTCCTCTGCGGCCTGATCAAGGATGAGCTGGAGCAGTACTTCCAGCACCAGCAGCAGGCGAACTCCTTCGTGCTGCCCTCCGCCAGCGAGGAAGACGAGGAGGACGAGGAGATGGAGGAGGAGCCGCGCCAGGAGAGCGGCGAGCGGAAGGTGCGGGTGCGGACGGCCATCAACGAGGAGCAGCAGCAGCAGCTGAAGCAGCACTACTCCCTCAACTCGCGGCCCAGTCGCGACGAGTTCCGGATGATCGCCACCCGGCTGCAGCTGGACCCGCGGGTCGTCCAGGTCTGGTTCCAGAACAACCGCTCCAGGGAGCGCAAGATGCAGAGCTTCCAGAGCAGCCAGAGCAACCCAGCGATGGGTGCCAACGAAGCAAGCAACACCTCTCTGACCCGCGAGGATCAGCCGCTGGACTTGTCCGTGAAGAGGGATCCCCTGACACCGAAAAGTGAGAGCTCGCCGCCCTACATTGCTCCACCGACGGGCGAGACCCTCAATCCCGAGGCCATCAACCTGAGCAGGAAGTTCTCCACCTCGGCGTCCATGTCCCCAGCCTCGATTTCGCCCTCCTCCGCGGCGGCCTTGTACTTCGGAGCTGCCCCGCCGCCCTCGCCGCCCAACAGCCAGCTGGAGGCCACTCCCCGCGGCGGCCAGGCCTTCCCGGGCATGCCCTACATGCTGCCCATGCCGCTGCCCATGGAGGCGCTGTTCAAGATGCGCCCCGGCGGGGAGTACGCCCCCAACCCGCTGATGAACAGTATTAAGCTGCCCGACTACCGCGGCACCAGCCTGAGCCCCGGCGGCTCCGAGAAGCGCTCCTGGCGGGACGACGACTCGCGCATCTCGCACGAGGACGACTTCGTCGGAGGCGGCGGCCTGATGCCCCCGAAGCCCCGCCGGGGAAAGGCGGAGACCCACGGCCACGCCGGCGATCCCGACCTGCCCTACGTGTGCGACCAGTGCGAAAAGGCGTTCGCCAAGCAGAGTTCGCTGGCGCGCCACAAATACGAGCATTCCGGTCAGCGACCCTACCAGTGCATGGACTGCCCGAAGGCCTTCAAGCACAAGCACCACCTCACGGAGCACAAGCGGCTGCACAGCGGCGAGAAGCCCTTCCAGTGCTCCAAGTGCCTGAAGCGCTTCTCGCACTCCGGCAGCTACAGCCAGCACATGAACCACCGGTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MSAAALLISSSSSLEKTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGSGSAGSRRSPSDLGKGKGLPVQPSLSGLPNPMIYFASDAQNQAGNAGPAPFPPFNPTNYMNAALLAFPNSFMVAAGLDPRVHPYSIQRLLHLSAAGQQQREEEREREQQQEDEETPDEPKLVMDIDEPEAKERVPTPPPAEEATPIKREESREASPAPEGYPASPPAIKQEQEPLPAVEEPEISVEEPPQAEQPADLRCSRCSKQFNHRTELVQHEKVLCGLIKDELEQYFQHQQQANSFVLPSASEEDEEDEEMEEEPRQESGERKVRVRTAINEEQQQQLKQHYSLNSRPSRDEFRMIATRLQLDPRVVQVWFQNNRSRERKMQSFQSSQSNPAMGANEASNTSLTREDQPLDLSVKRDPLTPKSESSPPYIAPPTGETLNPEAINLSRKFSTSASMSPASISPSSAAALYFGAAPPPSPPNSQLEATPRGGQAFPGMPYMLPMPLPMEALFKMRPGGEYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFVGGGGLMPPKPRRGKAETHGHAGDPDLPYVCDQCEKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00565272;
90% Identity: iTF_00507514;
80% Identity: iTF_00507514;