Basic Information

Insect: Drosophila ficusphila
Gene Symbol: Znf516
Assembly: GCA_018152265.1
Location: JAECXK010000775.1:8411209-8412875[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00039 0.028 14.7 1.1 1 23 206 229 206 229 0.92

2 8 3e-07 2.1e-05 24.6 2.7 2 23 251 273 250 273 0.94

3 8 0.00017 0.012 15.9 0.1 3 23 299 318 298 318 0.98

4 8 1e-06 7.1e-05 22.9 0.9 1 23 324 346 324 346 0.99

5 8 4e-05 0.0028 17.9 2.7 2 23 353 374 352 374 0.96

6 8 2.1e-07 1.5e-05 25.0 1.2 1 23 380 402 380 402 0.99

7 8 0.46 32 5.1 0.6 1 21 408 428 408 432 0.86

8 8 0.0023 0.17 12.3 0.3 1 23 494 518 494 518 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00039	0.028	14.7	1.1	1	23	206	229	206	229	0.92
2	8	3e-07	2.1e-05	24.6	2.7	2	23	251	273	250	273	0.94
3	8	0.00017	0.012	15.9	0.1	3	23	299	318	298	318	0.98
4	8	1e-06	7.1e-05	22.9	0.9	1	23	324	346	324	346	0.99
5	8	4e-05	0.0028	17.9	2.7	2	23	353	374	352	374	0.96
6	8	2.1e-07	1.5e-05	25.0	1.2	1	23	380	402	380	402	0.99
7	8	0.46	32	5.1	0.6	1	21	408	428	408	432	0.86
8	8	0.0023	0.17	12.3	0.3	1	23	494	518	494	518	0.92

Sequence Information

Coding Sequence: ATGGAAACAACAGAGATTCACATAACTATAAGTTCCCAAACGTGTCGCGTTTGTCTGGAAACCCACGAGACCACTTTGTGCCTCCACGATGAGATCGAGTACAACGACCTGAATATGGAACTCTGGGAGCTGTTGGAATCCGTGTCCAAAGTAAAGTACACCTGGACGGATCCGAATCTGCCGATGCAGCTGTGCCAAAGTTGCACTCGCCGGTTAATCAGTGCCTACGAATTCATTCTTGATGTAGAGAGTGCACAGAAAACTTTGCAGAATCTGTATCTGCAGCAAGTTGATGCACCCAAACCGGATGAAGGCCATGTGGAGGTGGTGCAGCTGGGTGGTCAGCAGGCCGTAGTCGATATGGAGGAAATTCGGTCCGCCTCTTACGAAGAGCAACAGACGGAAGTAAAGGAGGAGTTTGAAGACCTAGACACTTCCGAAATATTAAAATCTGAAACAGAAGAAGAGCCGCTGTATACAGCACAGCTTCACAAAGAGGATGCGGATCAGCCTGCTAAGCTACAGATATTGCCAGAGGAGCCAGAGAACCAACAATTATCTCAATCGCGACCTTCCCAGCTAGGCAGCCGTTTGTCCCACTCGGAGAACTTTATCTACAAATGTGCCGAGTGTCCACGGGTTTTTGCTAAAACCGAATCCCTCTCCCGACACTTTTCGCATGCTCACAGGCTGACAGCAGTCGTTGCCGCCTCGAAGTTGGCCAACGAGAGTAGTGGTACCGGCCTACTGACCTGTGAGCACTGTCCACGCTCTTTCAAGCGGCAGGACACCCTTCGCCGTCACATGCAGGCGTTTCATCCCGACGCAACGCCCTTGGAAACCGATGACGCACCGGAAAATTCGCCACGAAAACGGATAGCCAAGCGGAAAGACTGTCCCTACTGCGGCCTCAGCTTTCCTATGTCTAGCCTCACGATCCACATTCGCCGGCACACCGGCGAAAATCCGTATAAATGCAGCCAGTGCGAAAAGGCCTTCCCGCGCAGTCAGGATCTCAGTTTGCACATGCGCCAGCACACCGGCGAGCGACCCAGTGAGTGTAAGATTTGCTCCAAGAAGTTCATCTCACAAAACAAGCTGGCTCGGCACATGCATCTACATACCGGCCAAAGGCCTTACTCCTGCGACTTGTGTAGCAAGACCTTCGTGCAATCCAATGATCTGAAGATCCACATGAGGCGGCACACTGGCGAACGTCCATATCAGTGTGGAGTGTGCGGAGACAGCTTCGTTTGCGGCTCGCTCCTGAATATCCATCGGAACCAAAAGGGACATCAGGAGGCGGTAAACTCAGGCAATTTAACCGAAGGAGCCTTTGCTGCGGATCCCTATGAAAACTCCAGGGTCAACAAGCGACGGGCAGAAGATATCGAGCGCATGCGTCTGCAACGTGACCCCAGCGATCTACTACAACAGCAACAAGGAATTCCACCGTCCACTGAGCTGCCTTCAATGGCCTACAGATGCGGAGTCTGCGAGCAGAACTTCAAGAGCGGCGCCCTACTGACCATCCATCGCAATAAAATGAGTCATTATGAAGTAGGCAGGGACTACGGAGATCCCTTTGGTAAAAACAGAAAAAGCTAG
Protein Sequence: METTEIHITISSQTCRVCLETHETTLCLHDEIEYNDLNMELWELLESVSKVKYTWTDPNLPMQLCQSCTRRLISAYEFILDVESAQKTLQNLYLQQVDAPKPDEGHVEVVQLGGQQAVVDMEEIRSASYEEQQTEVKEEFEDLDTSEILKSETEEEPLYTAQLHKEDADQPAKLQILPEEPENQQLSQSRPSQLGSRLSHSENFIYKCAECPRVFAKTESLSRHFSHAHRLTAVVAASKLANESSGTGLLTCEHCPRSFKRQDTLRRHMQAFHPDATPLETDDAPENSPRKRIAKRKDCPYCGLSFPMSSLTIHIRRHTGENPYKCSQCEKAFPRSQDLSLHMRQHTGERPSECKICSKKFISQNKLARHMHLHTGQRPYSCDLCSKTFVQSNDLKIHMRRHTGERPYQCGVCGDSFVCGSLLNIHRNQKGHQEAVNSGNLTEGAFAADPYENSRVNKRRAEDIERMRLQRDPSDLLQQQQGIPPSTELPSMAYRCGVCEQNFKSGALLTIHRNKMSHYEVGRDYGDPFGKNRKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -