Dfic010578.1
Basic Information
- Insect
- Drosophila ficusphila
- Gene Symbol
- -
- Assembly
- GCA_018152265.1
- Location
- JAECXK010000405.1:2214498-2215445[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 4.2 3e+02 2.1 0.3 12 23 49 60 48 60 0.90 2 10 4.2e-05 0.003 17.8 0.9 1 19 66 84 66 85 0.98 3 10 4.8e-05 0.0034 17.6 7.3 1 23 94 116 94 116 0.98 4 10 6.1e-09 4.4e-07 29.9 2.7 1 23 122 144 122 144 0.99 5 10 1.5e-05 0.0011 19.2 1.5 1 19 150 168 150 170 0.97 6 10 8.4e-05 0.006 16.8 4.0 1 23 178 200 178 200 0.98 7 10 4e-07 2.8e-05 24.1 0.5 2 23 207 228 206 228 0.97 8 10 4.2e-05 0.003 17.8 0.9 1 19 234 252 234 253 0.98 9 10 9.6e-06 0.00068 19.8 2.6 1 23 262 284 262 284 0.98 10 10 1.5e-09 1.1e-07 31.8 2.6 1 23 290 312 290 312 0.99
Sequence Information
- Coding Sequence
- ATGGATGCCATTATAGATACAGATTCGGCGGAAGATGAGATTCTTACAATATCGGACAGCGAAAGTGAGAGGTCGGAGTCTACTCAGGGATCAGATTCAAATGGAAACAAAGTAACCACGGACGATGACACTGATATAGGTGAGTCGCGGTCGGGTCTTACCCACCATGGCAGAGTTCACTCGGACGAATGGGCCTACAAGTGCTCCCTATGCCTAAAGGCCTTCCGGAGCAAACGCGATCTTAAGCGCCACGGTGTTTGCCACTCTGAAGACCAACCCCACAAGTGTTCCCACTGCCAGTCAACTTTTTCCCTGAAAGCACACCTACAGCGACACATCCGAATTCACACGGAAGAAAAGCAATTTAAATGCGATCTTTGCGACAAGGATTTTAGGAAGAATTCAGACTTGAAACGGCACATGAGAACTCACACGGGAGAAAGACCCTACAAGTGCTCCCTTTGCCTAAAGGCCTTTCGGAGAAAAAGCCATCTTACGAGCCATGGTGATTGCCACTCTGAAGACCGACCCCACAAGTGTTTCCATTGCCTGGCAACTTTTTCCCTGAAAGGAAACCTACAGCAACACATCCGAATTCACACGAAAGAAAAGAAATTAAAATGCGATCTTTGCGACAAGGATTTTAGGTACAATTCAGCCTTGAAAGAGCACATGATAACTCACACGGGAGAAAGGCCCTACAAGTGCTCCCTATGCCTAAAGGCCTTCCGGAGCAAACGCGATCTTAAGCGCCACGGTGTTTGCCACTCTAAAGACCGACGCCACAAGTGTTCCCATTGCCTGGCAGCTTTTTCCCTGAAAGCAAATCTACAGCGACACATCCGAATTCACACGGAAGAAAAGCAATTTAAATGCGATCTTTGCGACAAGGATTTTAGGCGGAATTCAGACTTGAAACGGCACATGAGAACTCACACGGGAGAATGA
- Protein Sequence
- MDAIIDTDSAEDEILTISDSESERSESTQGSDSNGNKVTTDDDTDIGESRSGLTHHGRVHSDEWAYKCSLCLKAFRSKRDLKRHGVCHSEDQPHKCSHCQSTFSLKAHLQRHIRIHTEEKQFKCDLCDKDFRKNSDLKRHMRTHTGERPYKCSLCLKAFRRKSHLTSHGDCHSEDRPHKCFHCLATFSLKGNLQQHIRIHTKEKKLKCDLCDKDFRYNSALKEHMITHTGERPYKCSLCLKAFRSKRDLKRHGVCHSKDRRHKCSHCLAAFSLKANLQRHIRIHTEEKQFKCDLCDKDFRRNSDLKRHMRTHTGE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00507752;
- 90% Identity
- iTF_00507752;
- 80% Identity
- -