Dfic006122.1
Basic Information
- Insect
- Drosophila ficusphila
- Gene Symbol
- pros
- Assembly
- GCA_018152265.1
- Location
- JAECXK010000775.1:16253909-16265206[+]
Transcription Factor Domain
- TF Family
- HPD
- Domain
- HPD domain
- PFAM
- PF05044
- TF Group
- Helix-turn-helix
- Description
- Prospero is a large drosophila transcription factor protein that is expressed in all neural lineages of drosophila embryos. It is needed for correct expression of several neural proteins and in determining the cell fates of neural stem cells. Homologues of prospero are found in a wide range of animals including humans with the highest level of similarity being found in the C-terminal 160 amino acids. This region was identified as containing an atypical homeobox domain followed by a prospero domain. However, the structure shows that these two regions form a single stable structural domain as defined here [1]. This homeo-prospero domain binds to DNA.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 5.3e-87 8.5e-83 275.7 2.3 1 153 780 932 780 933 0.99
Sequence Information
- Coding Sequence
- ATGATGTCATCGGAGGAGTACGAGGCGGACTGTTTTGGTTTTTCGGCATCGTCCTTGCTGACGGCCGCATTTGGCAACCTGTTCGGTGGCTCCTCGGCCAAGATGCTGAACGAGCTGTTCGGCCGGCAAATGAAGCAGGCCCAGGACGCAACGAGTGGCCTGCCCCAGAGTCTGGACAACGCGATGCTAGCCGCCGCCATGGAGACGGCCACCATCTCGCCCAAGGGAAGTCGTCGGGTCTCCGCCTGCAGTGATCGCTCCTTGGAGGCGGCGGCCGCCGATGTTGCCGGTGGCTCACCGCCGCGAGCAGCTTCGGTGAGTTCGCTGAACGGCGGAGCCAGCAGTGGCGAGCAGCACCAGTCGCAGTTGCAACACGACCTGATGGCGGACATCAAGATCAAGAGCGAGCCCCAAACAGCTCCTCCGCCGCAGCAGTCGCCGCACGGGAGCAGCCACAGCAGCCGGAGTGGGAGTGGAACTGGAAGCCACAGCAGCCTGGCCAGCGATGGCAGTCTGCGGCGCAAGTCCTCCGACTCGCTGGACAGCCAGGGTGGCAACGATGAGCAGCAGGACGAGGACGACTCGGCTGTCAATCGCCAGAGATCCGAAAGATCCGAGAGTCGCGCTCCCGAGGGGCCGCAGTTGCCCACCAAAAAGGAGTCGGTGGACGATATGTTGGACGAGGTGGAGCTGATGGGCCTGCACTCGCGTGGCTCCGACCTGGAGAGCCTCGCCTCGCCCAGCCACTCGGACATGATGCTGCTGGACAACAGCAAGGACGACGTCCTCGACGAAGACGACGACGAGGATTGCGTGGAGCAGAAACGCGATTCGGGCAGTGGTTGTCTGAAGAAGCCCGGCATGGAGTTGAAGCGCGCCCGCGTGGAGAACATTGTCTCGGGGATGCGATGCAGTCCCTCCTCGGGACTGGTGCAGGCCGGTCAGCTGCAGGTGAACGGCTGCAAGAAGCGGAAGCTCTACCAGCCGCAGCAGCACGCCATGGAGCGCTATGTGGCCGCCGCAGCGGGACTGAACTTCGGCCTGAACCTGCAGAGCATGATGCTCGACCAGGACGACAGCGAGTCGAACGAGCTGGAGTCGCCGCAGATCCAGCAGAAGCGGGTGGAGAAGAACGCCCTCAAGTCGCAGCTGCGCTCGATGCAGGAGCAGCTGGCGGAGATGCAGCAGAAGTACGTGCAGCTGTGCTCGCGCATGGAACAGGAGTCCGAGTGCCAGGAGCTCGACCAGGATCAGGATCAGGATGCCGAGCAGGAGCAGGAGCAGGAGCCCGACAACGGCAGCAGTGACCACATCGAGCTCTCACCTTCGCCCACCTTAACTGGAGACGGTGATGTCAGTCCTGCCCACAAGGAGGAAGTGGGAGTGGAGCGACCAGGATCGAGTTCCCCTTCGCCTTCACCCTTGAAAGCCAAGGCAACGCTGGGCGAGGGTAACGAGTCCGGGGCCAACATGCTGTCCCAGATGATGAGCAAGATGATGTCCGGCAAGCTGCACAATCCCCTCGTAGGATCCGAGCTCTCGGAGAAGTTCCAGATGCTGCGCGCCAACAACAACAGCTCGATGATGCGCATGTCCGGCACGGACCTCGAAGGACTCGCCGACGTCCTGAAATCGGAGATCACCACCTCGCTGTCCGCCCTGGTGGACACCATTGTGACCCGCTTCGTCCACCAGCGGCGGCTCTTTAGCAAGCAGGCGGACTCGGTGACCGCAGCGGCGGAGCAGCTGAACAAGGACCTCCTGCTGGCATCGCAGATCCTCGACCGGAAGTCGCCGCGCACCAAGGTGGCGGACAGGCCGCAAAACGGACAAACGCCCGCAACACAATCAGCGGCTGCCATGTTCCAGGCGCCAAAGACGCCGCAGGGCATGAATCCGTCGAAGGTCTTCTCGCCGTACTCGCCGTTCTTCAATCCGCACGCCGCGGCCGGCCAGCCAACGGCCGCCCAGCTGCACCAGCACCACCAGCAGCACCACCCGCACCACCAGTCCATGCAGCTCTCCTCGAGTCCGCCGGGCAGCCTGGGCGCTCTGATGGATTCGCGCGACTCGCCGCCGCTGCCCCACCCGCCGTCGATGCTGCATCCCGCCCTCTTGGCGGCCGCCCACCACGGCGGCTCGCCGGACTACAAGACCTGCCTGCGGGCCGTCATGGACGCCCAGGATCGCCAGTCCGAGTGCAACTCGGCCGACATGCAGTTCGATGGCATGGCGCCTACTATATCCTTTTACAAGCAAATGCAACTGAACACACCCGAACACCAGGAGTCGCTGATGGCCAAACATTGCGAATCCTTGACTCCTTTGCACTCTTCTACATTGACACCGATGCACCTGCGCAAGGCCAAGCTGATGTTCTTCTGGGTGCGCTATCCCAGCTCCGCGGTGCTCAAGATGTACTTCCCGGACATCAAGTTCAACAAGAACAACACAGCACAATTGGTTAAATGGTTCTCAAACTTCCGAGAATTCTACTACATACAAATGGAGAAATATGCACGACAAGCTGTCACCGAAGGCATCAAGACACCCGATGATCTGTTGATTGCTGGAGATAGTGAATTGTATCGCGTGCTCAATTTGCACTACAATCGCAATAACCACATTGAGGTACCCCAGAATTTCCGCTTCGTGGTCGAATCGACACTGCGGGAGTTCTTCCGTGCAATACAGGGTGGCAAAGACACCGAGCAGTCGTGGAAGAAGTCCATATACAAGATCATATCGCGCATGGACGATCCCGTGCCCGAGTACTTCAAGTCGCCCAATTTTTTAGAGCAGCTGGAATAA
- Protein Sequence
- MMSSEEYEADCFGFSASSLLTAAFGNLFGGSSAKMLNELFGRQMKQAQDATSGLPQSLDNAMLAAAMETATISPKGSRRVSACSDRSLEAAAADVAGGSPPRAASVSSLNGGASSGEQHQSQLQHDLMADIKIKSEPQTAPPPQQSPHGSSHSSRSGSGTGSHSSLASDGSLRRKSSDSLDSQGGNDEQQDEDDSAVNRQRSERSESRAPEGPQLPTKKESVDDMLDEVELMGLHSRGSDLESLASPSHSDMMLLDNSKDDVLDEDDDEDCVEQKRDSGSGCLKKPGMELKRARVENIVSGMRCSPSSGLVQAGQLQVNGCKKRKLYQPQQHAMERYVAAAAGLNFGLNLQSMMLDQDDSESNELESPQIQQKRVEKNALKSQLRSMQEQLAEMQQKYVQLCSRMEQESECQELDQDQDQDAEQEQEQEPDNGSSDHIELSPSPTLTGDGDVSPAHKEEVGVERPGSSSPSPSPLKAKATLGEGNESGANMLSQMMSKMMSGKLHNPLVGSELSEKFQMLRANNNSSMMRMSGTDLEGLADVLKSEITTSLSALVDTIVTRFVHQRRLFSKQADSVTAAAEQLNKDLLLASQILDRKSPRTKVADRPQNGQTPATQSAAAMFQAPKTPQGMNPSKVFSPYSPFFNPHAAAGQPTAAQLHQHHQQHHPHHQSMQLSSSPPGSLGALMDSRDSPPLPHPPSMLHPALLAAAHHGGSPDYKTCLRAVMDAQDRQSECNSADMQFDGMAPTISFYKQMQLNTPEHQESLMAKHCESLTPLHSSTLTPMHLRKAKLMFFWVRYPSSAVLKMYFPDIKFNKNNTAQLVKWFSNFREFYYIQMEKYARQAVTEGIKTPDDLLIAGDSELYRVLNLHYNRNNHIEVPQNFRFVVESTLREFFRAIQGGKDTEQSWKKSIYKIISRMDDPVPEYFKSPNFLEQLE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -