Dfal002828.1
Basic Information
- Insect
- Drosophila falleni
- Gene Symbol
- -
- Assembly
- GCA_035045575.1
- Location
- JAWNOV010000014.1:4484359-4492173[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0029 0.22 12.2 2.2 1 23 1038 1060 1038 1061 0.95 2 8 0.19 14 6.5 1.0 1 23 1066 1089 1066 1089 0.96 3 8 0.00017 0.013 16.1 1.0 1 23 1304 1327 1304 1327 0.96 4 8 0.0026 0.19 12.4 0.8 2 23 1336 1357 1335 1357 0.97 5 8 0.041 3.1 8.6 0.3 1 23 1364 1387 1364 1387 0.96 6 8 1.6e-05 0.0012 19.3 1.4 1 23 1393 1415 1393 1415 0.97 7 8 3.2e-05 0.0024 18.4 6.7 1 23 1420 1442 1420 1442 0.99 8 8 0.0029 0.22 12.2 6.2 1 23 1448 1470 1448 1470 0.99
Sequence Information
- Coding Sequence
- ATGGTGGCAAAGTTTCGACGGCGTTGTGTGCGCGTCCAGCAGCGACTCCACGAGCTCGCCCAGGACATTGCCGAGCGGAAGGCCCGGCTTCGTCCCGACAAACAGGCACAACAAGAGCTGCCAAATGAGCCGGATGAGAAGGAGGCGGATTACATGCATCTGCCGGAATCACAATTGGAACGCAGGCGTCGACTGAAATCTGTTCAGCCGGAAATGGAGCCAAAAGAAGCTCAGACTGATGAGGCAGAGAATCCGCCATCGGCCAAATTGAGGCGCCTCCAACTGCGTGGCGCATCTCTGCCAgccaacaaaattgaaattgagactgaaactgaaactggaactggaacaacaacaacgacaagcTCGACAGACCAGAGCAAAACTAGAGAGAGATCCCCCAACAAAAAGACTCACGAGCCTTGGAGAACGAAGGCAGCTCGGAAGCAGCTTTCGGAAACCTGGTCTTCAAGCTCGACGAGCTGCGCCTACACAACAGACAGTCGGACCACGCCGGACGAGATCACACAGGTGGATACACAGCAGAATTCTACAAAGAGCAGCGTATCGACATCCATATCcccatcttcatcttcatcctcAACGTCGGGTCAAACGTCACCGGAGCACCTCAGCGATATATCCGTAAATCTATGTCGTGGCTTTTGCAGCGATGAGAATTCCTCCTCCTCAACAACAGTGTCCTCTCTTCAAGGTCAAACGACACCAGTTTCAAATGCCAAACTCCGATTTCCACCCAAACACTCGGCcaacaaccaaaacaaatCCCACATCGTTCTCCGCCGTGGGCGACGGGCACGTCCAACACTCAGTTACGGACCGGTTAGGCGACCAAGGCGCGTCTTAAAAAAGAAGCCGGAAAAGGAGCAGAAGTTGGCAATAGATCAAGAAATGCCCGAACAAGAGTTGCCCGAATCCAACTGCGAACCAAACAAACAATACGATAAAGCACCGAACGAGTTGGAAATCAAAATGGAAGAGGCGCCGTCCAGCAGTACGGATGAGACCTTAAAAACCACTTTAAATGGAAGCTCATTAAGGGCAAGAGATGATGACAATACGCCAAGTGAAAAGATAACAACGAACGACGCGGAAAAGGAATCGGAAATGTCCATGCTGGAATCCATAAGCGATGCAGTGCATCCTTCTGAGCTGAACAATGGATTACAGGATGCAACCAAGTCTGTAGATCAGGTAACAATCGCAGCGAATGAAAATCAGGTAGATAAATCGATGGAAACAACTCTGTCCATATCAAATGGACAGTTGTTAGTGGATAATCCAGTGCAATTCGAGGAATTGACGTCATCCACGGAACTTAATCGACAAATGACACCTGGAGTGCCATCCCCAGAATGCGAAGTGGAAGTAGAAGTCAGCTTGccaaatgatgatgatcagCAAAATTCCGAGTTGATCGTGAGCATACCACTTGACGCTCTCGATGATGAACTGCAGCGTAAACTCTGCAATCCTGGAGCGGATGTGGTGGTGGCAGCAGTTAGAGGTGAAGgtgaagctgaaactgaatcAGAGGCCAAAGATGAGGACGATGTGAATAACAATGCAAACGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCGACATCAAACAAATTGAAGCAGAACCAggtggaagtggaagtggagaAGAGAAGCCAATGGATGACGATGATATGACGTCAATAGAAGGACTCGTGAAACTGCCGGATGAGCAGCAGCATGCTGAGGTGCAATTACCAAGTTCAACTGCAAACTCCATGGATTTCCTGGCCGAATTTGAGAAGCACTGCGAGAAGACGTTGAAACTGCAAACGACGGAGCTGCAGGAGGCCAAACAGCAGATGCAGGTGGAAATGAACGATGTGGAGAGCACACTGCATGGCATACTCAATGAGATGCAGGATCAGCATCTCTATACGCCCGTCTGTACGCCCATTGATGAATTCCTAACGCCCGCCGATTATGCACCACTCAACGAACCGGAAATGGAATCGGAGTCGACCAATCTCTATGCGACAGATGTGCAGGTgcagcagcaggaacaacaacagcaacagcaacaacagcaacaacaacaggtgtTTGATAGCAGCAGCTTTAGCAATGAGCTGATtggctttcaaaatgataTGCCCTGTTTTGAGAATATTGAAGCATCTCCCGAGTCGATGGCGGCACAGCAGAGTCTGCAGCTGGAGCTGACACAGTTGCTCAATGATTTGCAGCCAGCtaacagtggcagcagcagcagcaacagcaacaatcaacagcagcaacagttgcagttgcagttgcaaccaGAGACGGTCAGCTACGATGCACTTTATCCAGCAGCGCCGGCAGCAACACCTGTTGCTCCCACTGCCACTGGCAacagctccagctccaacaAGGTGAAACTCATCCATGTGCCGCCACAGGAGACACTGTGGCAGGCACAAACGACAGCACAGCAGACGACACATTTGCAATGGTCAACGGTGGGCGGTTTGGAGTCCATCAAGACAATGCCTGTTGCCGGTTTGCCGGATGGCAACTTGGAGAACAGCCaacaagcgacaacaacaaccacgtACTACATCAATGCCAGTGATCTGTACCAGCAGCCAAGCAGCAATCTCACAGCGGATACCTATGCTGTGCTAGACAACAATGACAATTACGTGttggagcaacagcagcagcagcaacaacaacagcagcagcagcaacaacctaTTATGATACTCATACAGCAACCAGAGATGCAACAACCGGTGGCTTCTGCCAGCAATCCGCAGCAGGCACCATTGCACATCACGTATGCTCCACAACTTGGTAATGAAATACATGCGTtccagccacaacaacaacaacaaccacctacaccacaacaacagcaacatcgttcgaaacaacaagtacaaaatCATACAGTATTAGGCTTACCAGCAGCTGTGGCTCCGCCCACCCGAGGCAGACCGCCGATGTTAAAGTGCCGCTTCTGTCAGAATGGACCGCGTTTCTCCAGCAGCTTGGAATACAGTCGCCACATCATTGAGCTGCATCCGGCCGTGGCGCCCTTCAACTGTCCTCACTGCCCGCAGGCATTTGCCGGTCGCAGCAAACGCAATCAGCACATCCTCAGCCATCATGTGGTGCAGCAATTCCATTGCGGCCAATGCTCACAAATGTTTCCCGCTCAGCGTGCTCTCGACTTGCATTTGCAGCGATTCCACATGCCACTCGCCACGGACACGGCAACAGCTACGGCTACGGCAACTGATGCTGTGCGTATAGAGGAGGTGCAACTCCAAATTGCCACTaaggagcaacaacatcagccaCAATCCCAGCTACAGTCACTGCTACAAGCATCGTCGCAGCTGCAaaCTGTTGAAGCGCTAAAAAGCACAATGCAGACACGCAGGACGCGCATACTTTGTTGCCCGGACTGTGAGGACTGTAGCTCGTCGCCAACTGGACATCATCATCGCAGAATTGGACAGAATTACGAAGAGTTGAGGAATTTGCCGACACCGCCAACAGTGTTGACACCGCCATCAACCATTGCCTCATTGCCATCGCCACAGCCACAGTCACAGCTACAAGCAACGCCGCACATAACACTGCCATCGCCGGAGCAATCCGAGCCGGACTCGACAACTGCAACATTGCGACAATTTCGAAAACGTTGCACAGttagtggcagtggcaacactacaccaataccaacaacagcaacaacagcagctacaacaacaacaacaatgcttaTGGCAGCAGCATCTCCGTCCCCCTCATCATCGCCATCATCATCGACTATGGAAACGAgtgcgacagcgacagcgacactACAAATGAGTAAACTTCGTGGTAGCCATCAATGTGTTCTATGCGACAAGAGATTCACGAATATCATTGCACTGCGAAAGCATCAACAGTTGGCCCATGATTCGCAGACCACGATGCCGTGGGTTTGTTCAATCTGTAAGCGTGGCTATAGGAAACGCACCGATATGGATAATCATATGAAATCACACGAGCCAAAGGGCAGGCCATATGAGTGCAATGAGTGTTGGGTGCGATTTCCCGAATTTAAGCAGCTGGCAATGCACAAATTCACCGTACACGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAATTTCATGGTGAGCGCGGTTTCCAGTGCGAAGAATGCGACAAGTGTTTCGCACATATCAAAGATTTTCGAAAACATAGACGCACCCACAACAGTGAACTGTTTTACAAATGCGAACATTGTCCACGAACGTTTCTACATTTTACCAGTTTTCGCGCTCATATGAACACTCATTTGCCGTTGGGTGTATTCCTAAATGATAAATCAACTACATTGCCGATGCCAATTAAAACAGAGAGTCCCGCAACGCCCGGAACAAACGAGGAATTCCTGCCATTGACGCCGCTGAGCAACTGCAATGGAAACATCAATGAAGAATGCCCCGGATCCGTGGAGACGGTGGAGAGCAGCGTGGCACAATCGCTGGAAATGATTATTGATGCGCCATAA
- Protein Sequence
- MVAKFRRRCVRVQQRLHELAQDIAERKARLRPDKQAQQELPNEPDEKEADYMHLPESQLERRRRLKSVQPEMEPKEAQTDEAENPPSAKLRRLQLRGASLPANKIEIETETETGTGTTTTTSSTDQSKTRERSPNKKTHEPWRTKAARKQLSETWSSSSTSCAYTTDSRTTPDEITQVDTQQNSTKSSVSTSISPSSSSSSTSGQTSPEHLSDISVNLCRGFCSDENSSSSTTVSSLQGQTTPVSNAKLRFPPKHSANNQNKSHIVLRRGRRARPTLSYGPVRRPRRVLKKKPEKEQKLAIDQEMPEQELPESNCEPNKQYDKAPNELEIKMEEAPSSSTDETLKTTLNGSSLRARDDDNTPSEKITTNDAEKESEMSMLESISDAVHPSELNNGLQDATKSVDQVTIAANENQVDKSMETTLSISNGQLLVDNPVQFEELTSSTELNRQMTPGVPSPECEVEVEVSLPNDDDQQNSELIVSIPLDALDDELQRKLCNPGADVVVAAVRGEGEAETESEAKDEDDVNNNANDENFCQSATADSFNSAVALDIKQIEAEPGGSGSGEEKPMDDDDMTSIEGLVKLPDEQQHAEVQLPSSTANSMDFLAEFEKHCEKTLKLQTTELQEAKQQMQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYAPLNEPEMESESTNLYATDVQVQQQEQQQQQQQQQQQQVFDSSSFSNELIGFQNDMPCFENIEASPESMAAQQSLQLELTQLLNDLQPANSGSSSSNSNNQQQQQLQLQLQPETVSYDALYPAAPAATPVAPTATGNSSSSNKVKLIHVPPQETLWQAQTTAQQTTHLQWSTVGGLESIKTMPVAGLPDGNLENSQQATTTTTYYINASDLYQQPSSNLTADTYAVLDNNDNYVLEQQQQQQQQQQQQQQPIMILIQQPEMQQPVASASNPQQAPLHITYAPQLGNEIHAFQPQQQQQPPTPQQQQHRSKQQVQNHTVLGLPAAVAPPTRGRPPMLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPQAFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRFHMPLATDTATATATATDAVRIEEVQLQIATKEQQHQPQSQLQSLLQASSQLQTVEALKSTMQTRRTRILCCPDCEDCSSSPTGHHHRRIGQNYEELRNLPTPPTVLTPPSTIASLPSPQPQSQLQATPHITLPSPEQSEPDSTTATLRQFRKRCTVSGSGNTTPIPTTATTAATTTTTMLMAAASPSPSSSPSSSTMETSATATATLQMSKLRGSHQCVLCDKRFTNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFQCEECDKCFAHIKDFRKHRRTHNSELFYKCEHCPRTFLHFTSFRAHMNTHLPLGVFLNDKSTTLPMPIKTESPATPGTNEEFLPLTPLSNCNGNINEECPGSVETVESSVAQSLEMIIDAP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00523265;
- 90% Identity
- -
- 80% Identity
- -