Basic Information

Insect: Drosophila falleni
Gene Symbol: ush
Assembly: GCA_035045575.1
Location: JAWNOV010000142.1:3996206-4006720[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0077 0.58 10.9 0.0 1 20 308 327 308 329 0.90

2 9 0.00033 0.025 15.2 0.8 1 23 392 414 392 414 0.98

3 9 0.059 4.4 8.1 1.0 2 21 468 487 468 488 0.92

4 9 0.057 4.3 8.1 2.9 2 21 887 906 886 907 0.93

5 9 0.011 0.79 10.4 0.0 3 21 962 980 960 981 0.91

6 9 0.0077 0.57 10.9 0.0 2 23 1048 1069 1047 1069 0.98

7 9 0.0045 0.34 11.6 1.3 1 23 1075 1097 1075 1097 0.99

8 9 0.00081 0.061 14.0 0.8 1 23 1167 1190 1167 1190 0.96

9 9 0.48 36 5.2 0.5 2 20 1297 1315 1296 1317 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0077	0.58	10.9	0.0	1	20	308	327	308	329	0.90
2	9	0.00033	0.025	15.2	0.8	1	23	392	414	392	414	0.98
3	9	0.059	4.4	8.1	1.0	2	21	468	487	468	488	0.92
4	9	0.057	4.3	8.1	2.9	2	21	887	906	886	907	0.93
5	9	0.011	0.79	10.4	0.0	3	21	962	980	960	981	0.91
6	9	0.0077	0.57	10.9	0.0	2	23	1048	1069	1047	1069	0.98
7	9	0.0045	0.34	11.6	1.3	1	23	1075	1097	1075	1097	0.99
8	9	0.00081	0.061	14.0	0.8	1	23	1167	1190	1167	1190	0.96
9	9	0.48	36	5.2	0.5	2	20	1297	1315	1296	1317	0.91

Sequence Information

Coding Sequence: ATggcgacgacgatgatgatgacgacgatgacggCGACTCTGCCAGTTCGACAAATGAACAAAGGGTCGAATGCCCCCCAAACCCTTTTTATACCCGATGTCAGCTTGGCCGCTCTAATCATCAACTTGGCTTTGGAAcagcatccacatccacatccccATCCACATCCCCATCCACAACATGGAGCCATGCTCTCTGTGACCACCATGCGCTTTTCCACTCCACTCGCCGGTTTTCCACGTAATCCGACAGAGTCGAGATGCGTTCGCGGGATAAACAGGCAAGCAGTTGAACAGTTGAGCAGTCCAACAGCCAAATGGCCCAATGCTCAACTGGCCAAATGGCCAAATGGCCAAATGGTCGATTGGTCGACAACCTCGAACCTTGCTCATTCCAAAGATTTAGGTGCACACGAGCTGAGCGAggagaagcaacagcagcaacaacagcagcaggagttCGAGGGGCAGTTCGAGGAGCAGCCGGAGGACGAACACGGAGAGAACTCAAACAGCAACGCCTCCGATCAACCCATTGAGACTGACATGGATCCGGAAATGGTCGAGGCACAAGcggagcaggaggagcagcagAAAGAAGCGGACAATACGACGACGCCACCACGAAGTCCAACGCCTGAGCTAATTCCCAAGCTGGAGAGAATTGAGGAGCCGGCCACACCTCCCTCAGGGACAGCCACGCCCAGTCCACCGACTACGCCCACAACaacagtgctgccaaagcTGCGTCTGAATGCGCTACTCGCCTCGGATCCGGCTCTAAAACCCGATGCCAAGGAGCTGAATCTAACAGATGCACGTCTGCTCGGTCCGCCACATCAGCAGCTGTCGAAGCCGGAGCCGTCACAGAGTCTACCGGATTCCAGCAGCCTTGTGGAGCCGCTCTTGAAGCCGGCACGTTTCATGTGTCTGCCATGTGGCATTGCCTTCAGCTCTCCCTCGACGCTGGAGGCGCATCAGGCTTATTACTGCTCCCATCGCAACAAGGAGACGGACGAGGAGACGGCGTCGGCTGACAAGCTCGCATCCGCGGGcggagccggaggaggcggcgGCGTCTCCAGCACAGGCAACGGCAGcggcggaggaggaggtggagtAGGAGGCAGCAGCTCGGAGCCTCCAGCAAAGCTGGCACGCATTGGGAAGCAATATGCCTGCACTCAGTGCTCCTACAGTGCCGACAAAAAGGTCTCGCTCAATCGTCACATGCGCATGCATCAGACATCGCCGGCTTCCAGTCTCCCGAGCCTCTCCAGCCTCACAGCCAATGGCATTTCCAGCGGAGTTGGTATCGGAGCTGCTTCCGGGCTGGAAAGAGGATCCGGAGCCGGCGGCGGAGTCTCGCTCGAGGAGACCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGGTTCAACAATATCAAGACCTATCGCGCCCACAAGCAACACTACTGCAGTTCCCGTCGCAGCGACGGACAGCTGACTCCCAAGCCGGAGGCAGGagtcggagttggagttggagttggagtcggaccaggaggagcagcaggagcagcagctgttgccacTGGAGTTCCAGTTGGTGGCAGTGGCAAGTTGAGTGGCGCCCACAGTCCGCAGACGCGCAACAAGACGCCGACTCCGGCaatggttgctgctgctgcagccgctgccgctgctgccgcctCCCTGCAGGTGGCGCCACCTCAGCCCTTCCTGGCACTGCCCACCAATCCCATCATCATTGTGCCCTGCTCGCTGATCCGTGCCGCCAGCCTGATACCGGGACCACTCACCACCTCCACGTCGGGCATTGTTAATCCGGAGTCCACGTGCTTTACCCTTGACAATGGCGCCTTGAAGCCGCTGGCCACCGCTCTGAATATTAACGCCCTGGCGGGGAATGTCACCCCATCGCCGTTGCCCAGCAGCAACCAGCAGATGATTTCTGCCCTGGAACCAGATCGTCAGCCAGGAAATAGCAACAACTCCCTGGATGCGGATGTCAAGAGTAGTCCGCCGGAACCCAAGCGAAAGGAAGCGGGAGGCACACgtgagTCTACACCTCTGGATCTGTCGCTGCGTCGCTCTCCCATTGCGGCGCTGCTGCAGCGTCAGCGTCTCGTGCGCTCTGCCGCCGCGCTGCTCGAAGCGGAGGAGGCGCTGCTGagtgcagcagcaactgcagcagcatcagctgGCAAGGAGAATGTGGAGAGtggaggcggaggcggaggcggaggcggCAGCGTGACGCCGGAACAGATTGTGTGTGCTCCCTCGCTGCCGAGCAGTCCCTCGATGAGTCCCTCGCCCAAGCGACGAGCGGTGAGTCCACGAAGTTCTGGCGCGGGCAGCGCTGCTTCCATGTCGCCTCCAGCTTTGGGTGTGGGCGTGCCACATCTGCTGGATAATCTGCCGCCATTGCGTGCCATGTTGCCCACAGATTTTACGCTCTCCGAATCCTTGTTGGCCAAAACGAATCCCGAGCTGGCTTTGAAATTGGCAGCGGCTGCCGAATTGGCCAGCAAATTGGGATTCCCCGGCGGCGCAGCTGCtggtggaggtggaggagccacagcagtggcagcaacaaatgcCGGCAGTAATGCACCACAGATCTATGTGAAACAAGGCGTGTCCAAGTGCAAGGAATGCAACATTGTCTTTTGCAAATACGAGAATTACTTGGCACACAAGCAACATTATTGCTCTGCTCGCAATCAGGACACGGCTGAAGCTGGAGAAGCGAAGAACTCGAAGACGCCGCCAAGTGGCGCAGGtggagcagcagctggaggagcaggcgcctcctcctcctcctcttccgtGGTGGAGACAAATCCTGTGGCCTATCAACAATTGATTTGTGCCGCCTGTGGCATCAAGTACACCTCGCTGGATAATCTGCGTGCACATCAGAATTATTACTGTCCCAAGGGTACAGCCGCTGATCCCGGCCAGCTGACCCAGCCCAAGGAGAAGTGCGTCAAGTGCAAGACACTGCATGAACTTGCTCAGCCATGTCCGCCACCTCCAGCAGCGCTGCCTCAATTGCCGCCAGTCGGAGTCACTtcctcctcatcctcctccacctccacctcctcctcgTCGAATAGCGTCAACAAGTGTCCCGTTTGCGGCGTCGTTAGTCCCACTGCGGCATTGGCCCGCAAGCACATGGAGATGCATGGCACGGTGAAGGCATTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACATTGCGTGGCATGCGCACTCACATTCGCACCCATTTCGATAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACCTGCATCTTTGAGGAGGatccagctgctgctgctgctgctgctcccaCAGCTGCTTTAACACAGTCCATCGGTTTGGGACTGGATGTGCCCACTGTAGCCACTGTGGCAACACCTCAATTGGAGCAACTGGAGCAACAACAGGCGCAGCATCCGCCACAGATCTTCAACTGCGACTACTGCAACTATGCATCCACCTACAAGGGCAATGTGCTGCGCCACATGAAATTGTTGCATCCACATGTGGCAATCAGTTCGCCTTCCATATCGCCAGAGACCCGAGAGCAGGATAATAATGTACATTCTCTATCCGAAGTATCGCTGGTTAATGGTGATCGTGACACGCCAGCTAGCTTCCAGATCAAATCGGAGCCATTGGATCTACAACCTGTGGTAACACTGAGTCTAATGCATGAGAACAACAATTCACCGATAGGAACACCACACAGTCACATCAAGGCCGAACCCATGGACATTGATGTGTCGCCTCCAACGCTGCCGCCGCCGATGGCCAATTCACCATTGGGTCCAAGTGCCGCCGAGGCCATGAAAAAGTATTGTTCCACCTGCGACATATCCTTCAATTATGTGAAAACTTATTTGGCCCACAAACAATTCTACTGCAAGAGCAAATTGCATCGACCCGAGGCAAATGATAGCCCCAGTCCCAATCCTGTGCCCAACGAACTGTTGCTGCTCCAGAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MATTMMMTTMTATLPVRQMNKGSNAPQTLFIPDVSLAALIINLALEQHPHPHPHPHPHPQHGAMLSVTTMRFSTPLAGFPRNPTESRCVRGINRQAVEQLSSPTAKWPNAQLAKWPNGQMVDWSTTSNLAHSKDLGAHELSEEKQQQQQQQQEFEGQFEEQPEDEHGENSNSNASDQPIETDMDPEMVEAQAEQEEQQKEADNTTTPPRSPTPELIPKLERIEEPATPPSGTATPSPPTTPTTTVLPKLRLNALLASDPALKPDAKELNLTDARLLGPPHQQLSKPEPSQSLPDSSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKETDEETASADKLASAGGAGGGGGVSSTGNGSGGGGGGVGGSSSEPPAKLARIGKQYACTQCSYSADKKVSLNRHMRMHQTSPASSLPSLSSLTANGISSGVGIGAASGLERGSGAGGGVSLEETSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGVGVGVGVGVGPGGAAGAAAVATGVPVGGSGKLSGAHSPQTRNKTPTPAMVAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNVTPSPLPSSNQQMISALEPDRQPGNSNNSLDADVKSSPPEPKRKEAGGTRESTPLDLSLRRSPIAALLQRQRLVRSAAALLEAEEALLSAAATAAASAGKENVESGGGGGGGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAVSPRSSGAGSAASMSPPALGVGVPHLLDNLPPLRAMLPTDFTLSESLLAKTNPELALKLAAAAELASKLGFPGGAAAGGGGGATAVAATNAGSNAPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTAEAGEAKNSKTPPSGAGGAAAGGAGASSSSSSVVETNPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGTAADPGQLTQPKEKCVKCKTLHELAQPCPPPPAALPQLPPVGVTSSSSSSTSTSSSSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDPAAAAAAAPTAALTQSIGLGLDVPTVATVATPQLEQLEQQQAQHPPQIFNCDYCNYASTYKGNVLRHMKLLHPHVAISSPSISPETREQDNNVHSLSEVSLVNGDRDTPASFQIKSEPLDLQPVVTLSLMHENNNSPIGTPHSHIKAEPMDIDVSPPTLPPPMANSPLGPSAAEAMKKYCSTCDISFNYVKTYLAHKQFYCKSKLHRPEANDSPSPNPVPNELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575877;
90% Identity: iTF_00575877;
80% Identity: -