Basic Information

Insect: Drosophila falleni
Gene Symbol: sna
Assembly: GCA_035045575.1
Location: JAWNOV010000142.1:2174712-2175947[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 9.8e-05 0.0073 16.8 2.6 1 23 267 289 267 289 0.97

2 5 1.8e-05 0.0013 19.2 0.6 1 23 302 324 302 324 0.98

3 5 3.3e-08 2.4e-06 27.8 0.3 2 23 329 350 328 350 0.97

4 5 1.7e-09 1.3e-07 31.8 0.4 1 23 356 378 356 378 0.99

5 5 5.3e-06 0.0004 20.8 1.9 1 19 384 402 384 405 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	9.8e-05	0.0073	16.8	2.6	1	23	267	289	267	289	0.97
2	5	1.8e-05	0.0013	19.2	0.6	1	23	302	324	302	324	0.98
3	5	3.3e-08	2.4e-06	27.8	0.3	2	23	329	350	328	350	0.97
4	5	1.7e-09	1.3e-07	31.8	0.4	1	23	356	378	356	378	0.99
5	5	5.3e-06	0.0004	20.8	1.9	1	19	384	402	384	405	0.96

Sequence Information

Coding Sequence: ATGGCCGTCAACTACAAGAGCTGCCCGCTTAAGAAGCGTCCCATTGTCTTTGTGGAGGAGCTGCCGCAAACGGAGGCCTTGGCATTGACCAAGAGCTCACAGTTTGCGCCAGTCCAACAGCCGCAggatcagcatcatcatcatcagcttcAGCAGGAGCAACCACAGGATCTTTCGCTGAAACGTAAAGCCAGCGCGCTTGACTTTGAGGATTATGAGCTGCCGGCAAAGCGTGAATATGTCTTGAATCTGTCCAAGACTCCGATGACAGCGATAACACCGATAACACCACGCCGTATCAGCTCTCCACTCAGCTCGGCGCTGCTGTCGCCGCCGGCAGAGGAGCAGGATTATCAGCCAACTGATATACACATGCGTGGACTGACAGCTGCCACAGCCGGTTACACAACGAATCCCTATCAATCGGCATTTGTGATGGCCGCCGGCTGCAATCCCATCTCCGCCTTGTGGAGCAGCTATCAGCCACACTTGAATACGGCCGCATTTCCATCACCGGCCAGTTCAATGGCCTCACCGCATTCAGTGTACAGCTACCAACAGATGACGCCACCATCGAGTCCCGGCTCGGATGTCAGCTCCGAGCCCGAGGATCTCTCCGTGCGCAACGATATTCCGCTGCCGGCGCTCTTCCACCTCTTCGATGAGgcgcgcagcagcagcttggcctcctcctcctccgcctcctcATCCGCCTCCACGTACTCCTATGCCGCCTCCAacagctccagctccaactgcagcagcagcaactccgCAGCGGCAGCCAAGAACTATCGCTACAAGTGCGACAACTGCCAGAAGATGTACTCCACCTCGATGGGTCTGTCGAAGCATCGTCAGTTCCACTGTCCCGCCGCCGAGTGCAACCAGGAGAAGAAGCAGCACTCGTGCGAGGAATGTGGCAAGCTCTACAATACCATTGGGGCACTCAAGAtgcacatacgcacacacacactgcccTGTAGGTGTCCCATCTGCGGCAAGGCCTTCTCCCGTCCCTGGTTGCTGCAGGGTCACATTCGCACCCACACCGGAGAGAAGCCCTTCAAGTGCCCGGACTGTCCGCGCTCCTTTGCCGATCGCTCCAATCTGCGAGCCCATCAACAGACCCATGTGGATGTGAAGAAGTACGAGTGCAAGGAGTGCCACAAGTCCTTCTCCCGCATGTCCCTGCTCAACAAGCACAGCTCCAATTGTACCATCACAATTGTTTAG
Protein Sequence: MAVNYKSCPLKKRPIVFVEELPQTEALALTKSSQFAPVQQPQDQHHHHQLQQEQPQDLSLKRKASALDFEDYELPAKREYVLNLSKTPMTAITPITPRRISSPLSSALLSPPAEEQDYQPTDIHMRGLTAATAGYTTNPYQSAFVMAAGCNPISALWSSYQPHLNTAAFPSPASSMASPHSVYSYQQMTPPSSPGSDVSSEPEDLSVRNDIPLPALFHLFDEARSSSLASSSSASSSASTYSYAASNSSSSNCSSSNSAAAAKNYRYKCDNCQKMYSTSMGLSKHRQFHCPAAECNQEKKQHSCEECGKLYNTIGALKMHIRTHTLPCRCPICGKAFSRPWLLQGHIRTHTGEKPFKCPDCPRSFADRSNLRAHQQTHVDVKKYECKECHKSFSRMSLLNKHSSNCTITIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502699;
90% Identity: iTF_00523141;
80% Identity: -