Dfal016939.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila falleni
Gene Symbol
hang
Assembly
GCA_035045575.1
Location
JAWNOV010000185.1:8839653-8852957[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.37 27 5.6 1.0 3 23 497 518 496 518 0.93
2 18 0.46 35 5.3 3.2 3 22 625 644 623 644 0.89
3 18 0.00079 0.059 14.0 3.3 1 22 749 770 749 772 0.90
4 18 0.091 6.8 7.5 0.1 2 21 784 803 783 804 0.93
5 18 0.00091 0.068 13.8 0.2 2 23 926 948 925 948 0.95
6 18 0.0026 0.2 12.3 0.1 1 23 956 979 956 979 0.96
7 18 2.1e-05 0.0016 18.9 0.1 2 23 1065 1086 1064 1086 0.97
8 18 0.00038 0.028 15.0 2.9 2 23 1203 1225 1202 1225 0.97
9 18 0.03 2.2 9.0 0.2 2 23 1234 1256 1233 1256 0.95
10 18 0.0011 0.079 13.6 0.2 1 23 1269 1292 1269 1292 0.97
11 18 0.00016 0.012 16.1 1.1 1 23 1334 1356 1334 1356 0.99
12 18 0.0026 0.19 12.4 0.9 1 23 1364 1387 1364 1387 0.96
13 18 0.089 6.7 7.5 0.4 2 19 1395 1412 1395 1413 0.94
14 18 9.5e-05 0.0071 16.9 0.4 3 23 1515 1535 1514 1535 0.98
15 18 0.0066 0.5 11.1 0.1 1 23 1570 1592 1570 1592 0.97
16 18 0.00078 0.058 14.0 0.6 2 23 1691 1713 1690 1713 0.93
17 18 0.0084 0.63 10.8 0.3 3 23 1769 1789 1769 1789 0.98
18 18 8.9e-05 0.0066 17.0 2.1 1 23 2209 2231 2209 2231 0.99

Sequence Information

Coding Sequence
ATGAATCCCCTTTTCGTAAATTCCCTCATGCCAGAGGCTTCCTCTTATATGTCGCTCCTGTATCCAATTGCGATTTTGCCGCCATCATCGTCGCCACTTGAGAAAGAGATGTGCCCCCAACAGGACATCATTATCACGCCATTGGATCGTTTATCGCTGCATATTTGTCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGTCTCAGCTCCCAGTCGAAGCAACGACAATGGGTGGACATGGACAGAACCAAACAGCAGACACTATTGGGCTATTTGGATTTGAATCGGGCCGAGAATGGCAGCATTgttgaccaacaacaacaacagcaacaacaacagcagcaacaacaatcggaATTGAAAATCGATACGGCGACAGCTGCAGCTGAGAAGGCATCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCTTTAACAGTCTATGTGAgtccaaagcaacaacagcaacaacagcttcaacagcaacaacaacagcagcagcagcagcaacaactactaTTGCAAACGGCAAGAACGGAGCCACAGCAAACATTGCAGAATCTTTTATTGCAGGTGCCCACAACGGCGACAATGGCAATGGCGACAacatcacagcagcaacagcaacaacatcagcagcgcaaatatcagcagcaacaacgtggcaagcagcagcaacatcaccatcattatcaacaacaacaacatcatcatcaccagcatgcacaacatcaacaacatcagcaacaacaacaacagcgacataGACGCATGCGGCAGCCACGACGACAACAgtcgcaacagcaacagtcaaCGGCAAAAACTGTTGCTCATCGTTTGCCTAAATTTAAGCCAAAAGTGTATTTGCCACTTGATATTGCGGTGCCACCGCTGCCGCCACTGCTGACGACGCCATCGACATCAactgctgttgcaactgcaacagcaactgctactgttgctgctggtgttgctgaggcagctgcaacattgccattgccattgtcgttgccgttgtcgcAACCAATTGATTTCAGCCAGTGTAAGAATTCGAGTCAGAGTCAAAGATATGGCAGCGTCTTGCCACCGCCACCAACTCCAGTTGCCACAATGAGCAGCAACATCGCTAACGCACACGCaaccgctgctgctgcaagtgcaacagcaactgcaacaactccGCTGCTTATGCCGCCGCTGCCTGCTGTGCCCATCAAGGATGAGCCATTGGATGACACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGTGATGTGCCACTAATGACCTCCGATTATGATTATACGGCGCAGCATGGCGTAACGGCGGCTGTGGCAGCAGCATCGCTGCCGGCAACCGCTGTGGCAAATGTGGCCGCAGCCGGAGACTCAAAGGTGGCCAGTTGCCGTGCCTGCAGTTTGCAATTCTCAACACGGGCGAATGCACGACGCCATGAAAGGAATTTGCATCCGAATCTGTTTCAACTATCAACCGACTCGCCAAACAATACGCCAATAACAAAGCCGACTCCGGCATTGGCAGCCGCATTGGAGATACAACGTGCAGCGGCCGCGGCCGCAGCAACAGCGGAGGCAACAAAAGCGGCAGCTGGTGGCAACATATCGACACAAAAGTATCGCCAGGTGGTCATGAATACGTTCATCAAGTGTGAAAACGGCGGCTATGACTATGACAATCCGGAGCAATATCAGCAGCTGTTGAGCCGTGATAAGGTCGAGTTTATACAGGAGAATCATGAGTTTCTCGAGCAATATCAAACGATGACGTGTCGTTGTTGCAACAAATACTTTAGCAcctataagaattttatggCGCATGTGCGCAAAAAGTATCCCACATTGCCACGTAACTTGTGCTTCAATTGCCTCAAGATGAACGATTCGAAGGCGTTGTTTATATCGCATCTAAAAAAACGTAACTGCATCAATTTGTATCGTGTGCTTAATGCGTTGCGACTCAAACAGCCAAATTTTGCACATGCCACGGCAGCCGGTGTGATTGCAACCACAGAAACgctgccacaacagcaacaacaacaacaacagcagcaacaattgctggtAACAGCACATGAGACATCAGTTTCATCCGAGCGTCCAGAGAAATTGCGAGCCAAAGAGCTGCTGGTGAATAAACTCTATGAATGCAAGCTCTGTCCAAAGGGATTCCGCACAAAGCACGAATTCCGCACTCATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGTAGCTTCTGTGGCTTGGACTTTGCCGATCCTGTGGATCGGCGACgacattataataatatggaCTGCATTGTCCGTTTGCGCTGCATGACCTGCGATGCCAAATTGGAGACACATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGCGCTGTGAGCAGTGATAATGCCTCAACGGCAAACAGTGGCATGGATCATTCGCCGGGGAAGCGTAGTTTGCTTGGTGCTCTGGGCATTGGTGTTAGTCAATCCTCGAATGATGAATCCCGCAGCAGTAGCACCAACAATGCCGCCAATCCACCATTAACTTCCACACCCAAACTGGCAACATCATCGTCAGCAGCTCAGATTGGAGCTGCCAGTGGCGGCAGTCGTGATGCACCCAAATCCCAGTATTTCTCCCGCATGCCACAGGTCTGTCCGATTTGTGGCCAACagtacaacaactataacaatgTGCTGCGTCACATGGAATCAAAGCATCCAAATAAATTGCCCGAGACATACAAGTGTGTGCGTTGTGGATTGGGCTATCCAAGGATCTCATATTTGCGTGAGCATATGATCAATGTACATGGCGTTGATAAGAATCGTCATTCCGGCGGATTTGAGTATATTGTGAATGCGGATGCTGTTAAATTGGCCGATGGCAGTACACCAAATGTCTATACCGGACGCTACGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACTcgatgatgatgaggaggaAGGCGGTAGCATTGCCAAAAAGATGCGACTTGAcgatagcagcaacaacagcagcatcaacacaAGCATCGCCAATCAGCAAAAAGAGTGCCCCATTTGTAATGCGGTGTTTAGTAACAATATTGGCCTATCAAATCATATGCGTTCACATTACACAGCCTCATCGACGGCAACGAATGCAGCATTGGCGGCAGCCAATCGAATGACACCAAAATCGTTAACAATTACAGCAACACCGCCACTTGAggtggcagccacagcagcgactgcagcagcaacagcgactgcaacggcaacggcgacCGCAACAACATCTTCCTCCATTAgcaacgcagcagcagcaacaacagcaacaccagttagcacagcaacagcaactacaataTCTGCGATAACTGCAACAAAAGTGCCACCGGCAATGGTTAATCAAACGCCACAGGAACAGGCCGTATTCCGTCGGAGTTTAGATCAAGCGGCAGATCGTCGCTTTCGCCGGATGCGTTGTCGCATCTGTCAGCGTAGATTTAGCTCCAAGAAATCGTATCGCTATCACATGCTAACCGATCATCAGGTGCAAAATGTGCAATTTATCAAATGTAAATTGTGCAATGCCGAGTTTGCCTACGAGAAGGGATTGAAGGTGCATCTGTTCAAGGTGCATGGACGTGCCATCAAAGATGAGATGATTATCAAACAATTTGAATGTGATGTCTGTTCCATTGTGTACAGCTCCGAAATGGAGTTGCAACAGCATAAACGCAGCGTTCACAAATCACAATTGGGCACAAAATCATTGCATCtattatcatcatcaacatcaacagctaCTGCTACCTCTGCTGACCTGGCCGAAACATCCGGCAGTGCGTTAGCTGTCCTGCCATTATATTGGTATCAGTGCAAATATTGTCCATCCAATTTCAATACCAACAAGAAACTGGCCATTCACATCAATTCCCATGATGAGTTCGATTCCAATGATTATTCCTGCAAAGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTACATCGCTATAAGAAGCATCCGCAGGTACCGGATCCGGCGGAGTGCACGCTGTGCCGCAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCACACTCCCACCTGCAATCGCAAGCCAATTACGGCAACGGGAGCACATCAGcaggatcaacagcagcagcaacagcaacagttgcaactgcaacatcaacGTGGCATCTTCAAGCACAAAACGGGCGACGATGATgacgaggatgatgatgaggatcaACAGATGATGATAGATGATTCTGGtgctggtgttggtgttggcaaTGTTGCTAGTGACGGCAGCAATGGTGGCAACACTGTGGCAGCTGTCACCAGCAATACGAACACGATCAGTACAAGCAGCTTTAAGATACGCATACCAGAGGTGGCATGCACCATTTGTGGGGCACGTTTCACCGATCAGGAGATGTTCAGCAAGCACATTCAAAAGCATGAACAAGAATTATATGTGGATAATCCATTGGCTGCCATGTTCGATGATGGTCCAGCCGATGCTGGCCAATTTCAGGTGGAGCGACAAAATGAGAATGGGGAATATGCTTGCGATTTATGTGCAAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGctgaacaacaacaccaacaacaacaacaacagcagcagcagcaacagcaattcgATGTTGCATCTACGCGAATTGCATGCGGTGGGTCTGATGCCCAATCAGCAACatcagaagcagcaacagcagttgctgctgcaacaacagcaacaacaacagtctcagtcgagcagcagcaacaacaacaacaacagcaacaacagcaactcatCAGCCAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGTGCCTCAACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGTTGCACAAACATGAGGTCAGCAATCTACCCGAACCGCCAGTGATTGAAGTGGATGAACCGCTGTGTTGTCGTCGTTGCGGTGATTTAAAATTCGAGACGAAGGAATTGTGGATCGAACACAAATTGTCGGACGCAAAGGTTGTGCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTAAAGGAGGAGGTGATTGTGCCAGTTGTTGTCAATGCAAAGACAACAAAGAActtatcagcaacaacaacatcaacaacaacgacaacaacagcagcagcagcaggcacaagcacaacaacgacgacagcaacaacagcaaaggcaacagttgcagccacagcagcaacaacagcaacagcagcgactgcgacaacgacaacatcagGCAAAGTGCTGAAAGTCAAGGAGCTTGAAACTGAGAGAGGAGGAAAATTGAGTAAACAGCGTGCAAATGATAATGTGGAGCAACAAGCAGAGGAAAATGAGGATGATAGTGATATGGATGATGATAGCGATAgcgaggatgatgatgatgatgatgacgaggatgatgatgaagatgatgaggAGAATAGCACaagcgatgatgatgacgataatGATGtcgaggatgaggatgatgaaGGTGAAGATGTTGTTGCacagcagcaattgttgcagcaacacaacaacaataacagcaatgcaattgacaatgatgatgatgatgatgacgatctCATTGAGGAGGTTATCGAAGAGATTGACGATGACGACGGCGATGTACATGAGCAACATGTGATTGCCGCcaaatcaaacaacaacaaagtgaaCATTAATTATGCGCGCAGCAGCAATGCcaaattaaatggaaatggTGGCAAAAAGGCAAAGTTGCTAATCATGCATAGCTCTGGggaagatgatgatgaggatgatgatgaggaggaggatgaTGATGTGGAGGATGTGGAAATGGCAGAAGAGGAGGACGAAGAGGGTGTACACATGGGGGAAGTAATGACCATTGATGATATTATTGAAGAAGATGATGGTGAGGATGATGACGATGTGGTTGGTGTTAGTGGTGATGTTGTTGAagaggatgatgatgacgacaacgacaacgacgataatgatgatgatgatgtcgatgaggatgaggaggatGACGAAGACATTGATGaagatgacgacgatgatgatggcGACGTTCATCATGTGGGTCGTCGTCGTAATCGTAGCGTTGATGGTCGTGCCAACATCGGTGGTGATGCTGGCGATGGCGATGGTGATGGTGATGGCGATGTCGAtggtgatggtgatggtgatgGTACATCATCATCCGAGAGtgattcaacaacaacaacctcgCATTCAACTGGTGAGCGGCGTAAAAAAACTGTAGTTTCATCAGCGGCACATGGCGATGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTGCAGACACACATTAAAAGCCATTTTCTCAATGGGCCAACGGCGGGCAGCaaaaccagcagcagcagcaacagtggcagtggcaacaacaacaacagcagcaacggcaacggcagcagcagaggcaacaGTGGCGCCGCCAGCAGAAGCAACAATAATACTATTaatagtaacaacaataataaaagcaaaaccaaaaagtcCGGCTTGTTGGATGCTACCAAATGTGGCAGTGGTAGTGGCAGTGCAACAAccactgcaacagcagcaacagcaacaacggcaacaacaacgacgtcaacgtcagcagcgacggtgacagcgacagcggcagaaGCTGCAGCGCGCTTGAACTGA
Protein Sequence
MNPLFVNSLMPEASSYMSLLYPIAILPPSSSPLEKEMCPQQDIIITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWVDMDRTKQQTLLGYLDLNRAENGSIVDQQQQQQQQQQQQQSELKIDTATAAAEKASANILDGIPSLKKRKSLTVYVSPKQQQQQQLQQQQQQQQQQQQLLLQTARTEPQQTLQNLLLQVPTTATMAMATTSQQQQQQHQQRKYQQQQRGKQQQHHHHYQQQQHHHHQHAQHQQHQQQQQQRHRRMRQPRRQQSQQQQSTAKTVAHRLPKFKPKVYLPLDIAVPPLPPLLTTPSTSTAVATATATATVAAGVAEAAATLPLPLSLPLSQPIDFSQCKNSSQSQRYGSVLPPPPTPVATMSSNIANAHATAAAASATATATTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPATAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVEFIQENHEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPTLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATAAGVIATTETLPQQQQQQQQQQQLLVTAHETSVSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGAVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSTNNAANPPLTSTPKLATSSSAAQIGAASGGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLEVAATAATAAATATATATATATTSSSISNAAAATTATPVSTATATTISAITATKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSIVYSSEMELQQHKRSVHKSQLGTKSLHLLSSSTSTATATSADLAETSGSALAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQLQLQHQRGIFKHKTGDDDDEDDDEDQQMMIDDSGAGVGVGNVASDGSNGGNTVAAVTSNTNTISTSSFKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNNTNNNNNSSSSNSNSMLHLRELHAVGLMPNQQHQKQQQQLLLQQQQQQQSQSSSSNNNNNSNNSNSSASKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDLKFETKELWIEHKLSDAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVVVNAKTTKNLSATTTSTTTTTTAAAAGTSTTTTTATTAKATVAATAATTATAATATTTTSGKVLKVKELETERGGKLSKQRANDNVEQQAEENEDDSDMDDDSDSEDDDDDDDEDDDEDDEENSTSDDDDDNDVEDEDDEGEDVVAQQQLLQQHNNNNSNAIDNDDDDDDDLIEEVIEEIDDDDGDVHEQHVIAAKSNNNKVNINYARSSNAKLNGNGGKKAKLLIMHSSGEDDDEDDDEEEDDDVEDVEMAEEEDEEGVHMGEVMTIDDIIEEDDGEDDDDVVGVSGDVVEEDDDDDNDNDDNDDDDVDEDEEDDEDIDEDDDDDDGDVHHVGRRRNRSVDGRANIGGDAGDGDGDGDGDVDGDGDGDGTSSSESDSTTTTSHSTGERRKKTVVSSAAHGDAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPTAGSKTSSSSNSGSGNNNNSSNGNGSSRGNSGAASRSNNNTINSNNNNKSKTKKSGLLDATKCGSGSGSATTTATAATATTATTTTSTSAATVTATAAEAAARLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575750;
90% Identity
-
80% Identity
-