Basic Information

Insect: Drosophila ezoana
Gene Symbol: zfy1
Assembly: GCA_035045725.1
Location: JAWNOU010000044.1:11116732-11131803[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 5.6 4e+02 2.0 0.2 1 20 636 655 636 659 0.76

2 6 0.35 25 5.7 1.9 1 20 665 684 665 686 0.93

3 6 7.7e-05 0.0055 17.3 2.0 2 23 698 720 698 720 0.96

4 6 0.072 5.1 7.9 0.4 1 23 730 753 730 753 0.94

5 6 3.5e-05 0.0025 18.4 1.0 2 23 761 782 760 782 0.97

6 6 0.37 26 5.7 2.0 1 23 788 813 788 813 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	5.6	4e+02	2.0	0.2	1	20	636	655	636	659	0.76
2	6	0.35	25	5.7	1.9	1	20	665	684	665	686	0.93
3	6	7.7e-05	0.0055	17.3	2.0	2	23	698	720	698	720	0.96
4	6	0.072	5.1	7.9	0.4	1	23	730	753	730	753	0.94
5	6	3.5e-05	0.0025	18.4	1.0	2	23	761	782	760	782	0.97
6	6	0.37	26	5.7	2.0	1	23	788	813	788	813	0.94

Sequence Information

Coding Sequence: ATGacgctctctcgctcgctgcTCAAAAGCGAATGCCCGCACAAAGGCACAAAGCATGAACTGTGGCGTGGCCTGCCGCCACCGTCACCGGCGCACACGCCCACGAAGGGATTCGATGGAAACTTCAAGCTGGAACCGAATCTGAGCGTGAAAGACTTTGCCCCACCGCCGGAGAATGGCAACGGTAATGGCAATGGCAGCCTCGAGTCCGGCGGTCCGTCCGTTGccatggccacgcccacgcctcCGCAGCGCAAGCGCTACAAGAAGCGTGTGCAGTTCACCACCGACGCCCTAAATGGCTATGCGGGCGCCAAGGCCAAGGGTGGcgctggcgttggcgttgcagctgctggcgctggcgctgccacagctggcggctacaacaacaataacaacaacaacaacaacaactttggcaCAACAGTCAAGTCGAAGAAGCAGGAGGCAAAAGCGGCCGCGGCTGCCCTCAAGGCAGgcgctgcggcagcagcagcagcagcagcagcggcggcagcctCGTCGGCACTGCCCGAGGTGCTCGACTGTCGCATCGCGGAAAAGATCAAGAGCGAACTGGAGGCCTGCAGCAAGGAGTCGCTGCCAAGTGCACTGTGCCTCAAAaaggctgctgcagctgccgcagccgctgcagcggcagcgcgtCACAgtgacgacgacgaggacgaaGAGGACGACCGTcatcagcaacatcaacagcaacagcaccagcaccagcagctggcggcgcCGACAGCAACGGCATCGGGCACGCTGGTGGGCACTGGCTGCGGCGGTGCGGACATGGTGGATGCCAGCAGTGCCAGCAACGGGCAGCTGGGCAACTTCCATGTGCGATCCAAGAGCCAGGCGGGCAACAAGAAGTCGCAGTCCGCGAAAGCAgccgctgcggcagcagctgcagcggcggcggcagcagcagcggcagcggcgtccATGATGCCGCCGAACAGCTATGATGAGCCGGAAGATGATTCGGCTGTTGGGCCgggcgatgatgatgacgaggACGATGAGGAACTGGACGAGGAGGCGCTGGCGcgcgaaatgaaaatggagCAGAACTTTGTGGAAGAGGAGGATGAGCATGATATCGCGTTCCGGTCGCAACAGTCCTGCCGCGAATGCTCCATCTCGCATGACCACAAACTATGCCCGCTGCGCAATGCCTGCGGCAATGTTACGGACGCAGTGGACCTGGCTGAGTGGATCGAGCGCCGCAATCTGGAGGCTTTGGCCAAGCTAAAGGCGGACGCACAGCGCCAGGCCAAGGTGGGCAGGCCGCGTCACGATGACGATGAGGACGACATGgaggacatggacatggacgaGTCATCGCAATTGTCCGAGCTGGAGACCAAGCCGCTAATAACCTTCGCCGAGGCCTCGGTGCCCGCCGAATTCGAGCTGCACAACGTGGAGCCCAATGTCACCGGCGTCTTTGCCCGCACCGAAGTCCGTGCCTACACCAAACTGGGCCCACTCATCGGCCAGCCGGTGCAGAGCGGCGAGGTGCGCGAGGGCAGCGACATGAAGTGGATATTCGAGATGTGCGAGGCCGGCGCCGACAAATCCTATCTGCTCTGCTGCGATAACCCCAACGCCTCCAACTGGCTGCGCTTCATCCGACCCGCGCCCAGCTACGAGGAGCGCAATGTCAATCTCGTTTCCATCGATCGTCAGGCGTACTTTGTCAGCTGTCGCGATCTCCGCAACGGCATGGAGCTGCTCTACTGGAGTGACGACTGCAACACCATGTGGCGCAAGAAGCATACGGAGAAAACAAACTGCGGCGGCTGCAATTTGAAGTTCGAGCATCCGCTTTACTACCGCACGCACTGCTCAGTTTTTCACGATCCATCGATGAGCCTAACCATACGGAAGTACCACTGCAAGGTGTGCGGCGAGGCGGTGCTGGGCAAGGACAACATCATGAAGCATGCGGCCGAGAAGCACGACGGCAAGGGCGCCTATCAGTGCCAGTTCTGCAACAAGTTTTTCCTACGCCTCAACTATCTGGAAATGCATCGCACCTACGGCTGTGCGTCGAACCCGAACCGATCGCGGCCGGTCTGCGATTTTTGTGGTCGCAAATTCTGTCAGCCGCAAAAGCTGAAGGCGCACATTAAGCGCGTCCACAGTGaTATGGCTGAAGTTTTACGAGATTTTCAGTGTAAATTATGTTCAAAACTTCTAGGATCGCGTGCGGCATTGCAGCGCCACTCGAAGGAGGTGCACAGCCGCAACTCAACAGTCGTGAGTTGTCCGCGCTGCCAGAAACTCTTCCAGAATCGCAGCAATCTGAAGATCCACATGCTCACGCATTCGGGCGTGCGTCCCTTCAAGTGCGCGGAACCAGAGTGCAATGCCGCCTTCACCACGAAGCAGTGCCTACAGTTCCATTACAAGAAGGTGCACAACTATACCCAGGAGCAGATGCCGAAGATTGAGCGCAGCGTGGCCTACACTTTCGATGCCTACTCGGGCGGCATGAAGGTGGACTTTCTGGAGCAAGCACCGCGTCGGCGACGCAAGAGCCTTGAGGATCAGAACCAAAACTCGATGCTCAGCAGTTCGATGCAAAGCGACACCGAGTACAGCGACGACAATATATTCGAGGCCATCAAGAAGAGCGGAAAATCTATCAAGGATCTGTGCCGCAACGAGCCGAATCTCTCACTGCTCAGCTCAAAGATCTCCAGCATATTTGGCGAGAAGGTGCCACCTGTGCAACAGGTCTCGGGCCAGGTAAGCGCCGTTGTCTCCGCCAGCGCAGCTGGCACTGGACGCAAGCGCAAGCGGAAGAAGGAACCGGCGATCCCATCCCTCaccgcccagcagcagcagcagcagcaacaacagcaacagctgcagcagcagcaacacgccCAGCAgtgccaccagcagcagcagcagcagcaacaacagcagcagcagcagctccatgGTGGACATCTAGATCAGTCGCCCTCGCATCTGTCCcatcagcagcaccagcagcagccgcagtatCATGcgcacagccacgcccacgctcATGTGCATGCACACgcccaccagcagcagcagcaacagcagcagcagcaacagcaacagcaggcggccgcgcaccaccagcagcagctgcacgatgccgacgaggaggaggagagcGTGCGTCTGGAGCAGGTGCGTCGCAAGCAGAACGCCCAGCTCAGCCTGGTCGAGTCGTTCCTGACCACCACGGCACAGCGCCTCAGCGCCCAGCAACAGGTGCAGCAAGTGGTCGCTGCCGCGGCGGCTGTCTCGGCCATGGCCGGCGCTGGCGAGGATCCCGCCAAGCTGGGCCACATGATGGGCCACATGGGCGGCGTGGGCGTCGGCGTAGGCCTggacgatgatgacgatgacgacgaggaCGATGAGGATGCCACAGCGCACCACCTgcatcaccagcagcaacagcaccaacagcaacagcatcagcagcaccaCTCGCACCAAGCGCATCCACATCATGCACACACGCATCCCCACCAGCACGGACAGCAGGCGGCGCAGCAGCCGCACGATGCCGGCTATCGGCATGCGGCCGCCATGAACGCGGCCCTGGGCCAGAACCTGGTCGTCAGCAAGGGCAGCAAGAAGTGGATTGGCGCCGACGATCGCCATTTGAGCGATGGCGGTGACGTGGCCAATGATGCAGCAGTCGGCGGTGCGGgcagcggcggtggcggcggcggtggtgtcGTTGTCGGATGCGGTCAGCTGTCAGGTGGTGCCAGTGCTGGTCAGGACCTCGGTTTCGCAGTGCCACCCAGCGCCGTGGACGAGCACAGCAAGCTGCTGGGCCAGAACCGAGACTTCCTGGCACGGCTCAtgagcagcgccagcgccagccaTGCCAGCCATCAGCATCAGCACAGCGCGCACAGCCGCGAGGAGGACGAGAACAGCTCCTTCCTGGATGTTGTCGAGTCCAACAATAATgcggccgccgctgcagccgccgccgccgccgccgcggccATGTCACAATATCATCACAGTGCGGCTGCCAATGGCGGTGCGGGCGCTGCtggcggcgccggcggcggtggcggtggtgcTGGCGGGCACACGCCCACCGGCCACACGCCCACAGCGCCCAGCAGCGTGGACCCgccccaaatgcaaatgaactCGCTCAGCCACTCGCAGTCGTTCATGAGCTCCTTCTACAACAACGCCAACGCAAGACTGAGCGGCGCCGGcgctggcgttggcgttggcgtcggcgCCAACTCCTCCTCGGCCAGCATGCTGGTGGAGGCGGCCCTCAACTCCGTTGGCAATATGATTGACAGCGAGAGCAGCGATCTTAAGGTACCCACCGAGAACCACATAAATAGCGATAGTCCGATGAGTGCGCACGTGGATGCGGAGGCGCAACGCTTTGGCAGCGGCGGGGGCGGTGGGGGCAGCGGGCCGAACGGTGCAGGCATTGGGGCGACCATGGACAACCTGGAGAATGAGCTGAAGATGATGAAGAACCTGGGCAGCTTTCCCATGCAGATACCGCCTTTGCCTATGTTCCAGGGCGCCTGCAATATATCGCCGAGCGCCTCGACGCCCACCAATCCGCAGAGTAATCAGAATCAGAacgatgtggatgtggatgccGGCAGCACGCCGCGGCCGCAGCATCCGGACTCCGATGGTTTCTCCTCGTCGCACCACCGTACACCGCCCTCGCCGCCGCCCATATCGCCGGGACGCGACTACGGCGGCATGTTTGGCGCCGGCAATGGTGCTGGCGGGCCCGGCTCGAACAGCACGCCAGCGGGCAGCTCCAGCGGCGGCGGTGCTCCAACGGTTGGTAACAATTTGTCCGCATCTTCGCCGCTGCCGGCGTTGCAGCCGCAGCGACGCAATGCCTCCAGCGTGGGCAGCACATATCCCGAGCATGAGCTCATCTCGCCCGCCTCCTCGCCGAGCATACCGCGCTACAACTTCAACGGCGACATGATGCGCCACAAGCGCGCCGTCCAGGAGCATGAGCAGCAGGATCGACGCCACAACATCTCGCGTCACAATCACATGTCCAGCGACGAGGAGAACAGCATCATGCCACAGAACAGCGCCGGACAGGATATGCGCATGAAGTTCCCGCAATCGCAGATCGATCTCATGTACTCCAAGTACGAGAGCATGGCCAGCAATCTGAAGTACAACAGCCAGGAGCTGGACTCCCCGGTCGAGTACCggcagagcagcaacagcaatgcaGCAAGCgccgcggctgctgccgccgcggcAGCCAGCGCCGCGAATGACATGTCCGATCTGCAGGGACTGGACATGAGCTCGCGGTCGAATGCCTCGAGCAATTACCATCACAATTTCCAGCTGCCAAGCAGTCGTTACCATCACCACATCTACGATATATTGTCCGATCGGGAGCAAAACCAgcaggcgcaggcgcagcagcagacgccAGCCTCGGTGGTGCATCAGCAGGAGCATGGCAGCCATGGCGGTCACAGCAGCCAGCTGGCCATGCAGCAGCACCAGTCGGCGGCGATGCACAACATGCTGAGCGAGCAGCTGGGCGAGCAGGAGCACGACCAGACCACATCGGTGGACCTGAGCCGTACCGCCAACTATGTGGTGTCGTCTCCGCCGCAGCTGCCCTACAACCATCCGCACCACGATATGCTGCGCATGGCCTCGCTGGATCTGACACCAAATACGGCCAATATGGCCGTGGGCAACAATCGTTCGTTTCTGTCCTCGCAGATGCAGCACCAGAGCCGCGAGAGTCTCGAGCATCATCGGCTGCTCTCGACGGTCGAGCAGCATCGCATACTGGCCGCCTCGAATGCGGCGGCGGATCAGCATCGGCTGCTGGTCGATCCCACCGCCCATTTGCTGATGGAGCAAAACAATCGGCTACTGGGCAGCGCGGATCAGTCCCGTCTCCTGGGCGAatcggcggcggcagctgcccaGAATCGTCACATGGCCAGAAGCTTTGGTGCCTACCATCAGGTGGCATCGAGCAATTATCATCCGGGTGTACGGCCACCGCCGGTGTTGCCATCGGCCAACCATCATGCTTCCAATCCGTCGAATTATCATCCATTTCCGGCCTACTACTAG
Protein Sequence: MTLSRSLLKSECPHKGTKHELWRGLPPPSPAHTPTKGFDGNFKLEPNLSVKDFAPPPENGNGNGNGSLESGGPSVAMATPTPPQRKRYKKRVQFTTDALNGYAGAKAKGGAGVGVAAAGAGAATAGGYNNNNNNNNNNFGTTVKSKKQEAKAAAAALKAGAAAAAAAAAAAAASSALPEVLDCRIAEKIKSELEACSKESLPSALCLKKAAAAAAAAAAAARHSDDDEDEEDDRHQQHQQQQHQHQQLAAPTATASGTLVGTGCGGADMVDASSASNGQLGNFHVRSKSQAGNKKSQSAKAAAAAAAAAAAAAAAAAASMMPPNSYDEPEDDSAVGPGDDDDEDDEELDEEALAREMKMEQNFVEEEDEHDIAFRSQQSCRECSISHDHKLCPLRNACGNVTDAVDLAEWIERRNLEALAKLKADAQRQAKVGRPRHDDDEDDMEDMDMDESSQLSELETKPLITFAEASVPAEFELHNVEPNVTGVFARTEVRAYTKLGPLIGQPVQSGEVREGSDMKWIFEMCEAGADKSYLLCCDNPNASNWLRFIRPAPSYEERNVNLVSIDRQAYFVSCRDLRNGMELLYWSDDCNTMWRKKHTEKTNCGGCNLKFEHPLYYRTHCSVFHDPSMSLTIRKYHCKVCGEAVLGKDNIMKHAAEKHDGKGAYQCQFCNKFFLRLNYLEMHRTYGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRVHSDMAEVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSTVVSCPRCQKLFQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQCLQFHYKKVHNYTQEQMPKIERSVAYTFDAYSGGMKVDFLEQAPRRRRKSLEDQNQNSMLSSSMQSDTEYSDDNIFEAIKKSGKSIKDLCRNEPNLSLLSSKISSIFGEKVPPVQQVSGQVSAVVSASAAGTGRKRKRKKEPAIPSLTAQQQQQQQQQQQLQQQQHAQQCHQQQQQQQQQQQQQLHGGHLDQSPSHLSHQQHQQQPQYHAHSHAHAHVHAHAHQQQQQQQQQQQQQQAAAHHQQQLHDADEEEESVRLEQVRRKQNAQLSLVESFLTTTAQRLSAQQQVQQVVAAAAAVSAMAGAGEDPAKLGHMMGHMGGVGVGVGLDDDDDDDEDDEDATAHHLHHQQQQHQQQQHQQHHSHQAHPHHAHTHPHQHGQQAAQQPHDAGYRHAAAMNAALGQNLVVSKGSKKWIGADDRHLSDGGDVANDAAVGGAGSGGGGGGGVVVGCGQLSGGASAGQDLGFAVPPSAVDEHSKLLGQNRDFLARLMSSASASHASHQHQHSAHSREEDENSSFLDVVESNNNAAAAAAAAAAAAAMSQYHHSAAANGGAGAAGGAGGGGGGAGGHTPTGHTPTAPSSVDPPQMQMNSLSHSQSFMSSFYNNANARLSGAGAGVGVGVGANSSSASMLVEAALNSVGNMIDSESSDLKVPTENHINSDSPMSAHVDAEAQRFGSGGGGGGSGPNGAGIGATMDNLENELKMMKNLGSFPMQIPPLPMFQGACNISPSASTPTNPQSNQNQNDVDVDAGSTPRPQHPDSDGFSSSHHRTPPSPPPISPGRDYGGMFGAGNGAGGPGSNSTPAGSSSGGGAPTVGNNLSASSPLPALQPQRRNASSVGSTYPEHELISPASSPSIPRYNFNGDMMRHKRAVQEHEQQDRRHNISRHNHMSSDEENSIMPQNSAGQDMRMKFPQSQIDLMYSKYESMASNLKYNSQELDSPVEYRQSSNSNAASAAAAAAAAASAANDMSDLQGLDMSSRSNASSNYHHNFQLPSSRYHHHIYDILSDREQNQQAQAQQQTPASVVHQQEHGSHGGHSSQLAMQQHQSAAMHNMLSEQLGEQEHDQTTSVDLSRTANYVVSSPPQLPYNHPHHDMLRMASLDLTPNTANMAVGNNRSFLSSQMQHQSRESLEHHRLLSTVEQHRILAASNAAADQHRLLVDPTAHLLMEQNNRLLGSADQSRLLGESAAAAAQNRHMARSFGAYHQVASSNYHPGVRPPPVLPSANHHASNPSNYHPFPAYY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00803235;
90% Identity: iTF_00491147;
80% Identity: -