Basic Information

Insect: Drosophila ezoana
Gene Symbol: -
Assembly: GCA_035045725.1
Location: JAWNOU010000038.1:1782698-1785342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0021 0.15 12.7 5.1 1 23 643 665 643 665 0.98

2 5 1.6e-05 0.0011 19.4 0.4 2 23 678 699 678 699 0.98

3 5 0.00051 0.036 14.7 1.7 3 23 708 728 707 728 0.99

4 5 0.00089 0.063 13.9 1.3 1 23 733 758 733 758 0.92

5 5 0.026 1.9 9.3 0.2 1 21 766 786 766 790 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0021	0.15	12.7	5.1	1	23	643	665	643	665	0.98
2	5	1.6e-05	0.0011	19.4	0.4	2	23	678	699	678	699	0.98
3	5	0.00051	0.036	14.7	1.7	3	23	708	728	707	728	0.99
4	5	0.00089	0.063	13.9	1.3	1	23	733	758	733	758	0.92
5	5	0.026	1.9	9.3	0.2	1	21	766	786	766	790	0.91

Sequence Information

Coding Sequence: ATGATGGACCGCAAGAAGGTGCTTGAATTGGACAAAATCTGTCGCTTATGCATTTCCGAGCGCAAGGAAATGCGCCCACTTTTCAGCGAAAAAGTGCCCGAAATGCTTATGGATTGCACCAGCGTGCGCGTCGAGCCTACCGAGGGCTGGCCCGATAAAATTTGTGTGCAGTGTGTCCATGCGGTCAGTCGAAATCATGCATTTAAGTCGCTCGTCGAGCGCAGCGACAAGGAACTACGTGAATATATTAAAAGCTTGACGGTGCGCATGGTGATGGATGAGTCGCTGACGCCGCAAGAGCGAAAACAGCAGAAACTGTTACAAAAGCagctcaagcagcagcagcagcttgaggagcagcaacagaaacttgaacaacaaattatgcagcagcagcagcagctgcaacagcaacaacagcagcagcaacaacagcaacaacagcaacagtcgtCTATATTCCTGGTGCAGCAaccacatcagcagcagcatcaacaacaacaacaacagaagcccaaaaacaaattgaagccGCTGCTGCGCAAAGGAACCTCACGGCAGTCCAAGAAACAGCAAGATGTGGTACAGTTGTTGCCGGAGCCtgcgccaccgccgccgcctccacaGTTAGTtacccagcagcaacagcagcagatacAACAGATTCAACTGCCCACGCTGCAGCCGGCTCCCGCGCAACTTATGCCAACAACGACGGCGCAGCAAATCCTCTTGCCGAACGGCCAGTTCATAACGACGCAAATTGTGACGCCGCAGCTGGCGCAGATTATCGGCGCCCAGACGACGACATCGAATGCTACAGCCTCAGCACAGGCACAATTCCTGCCACAGTTGCTGCAGGCGCCCAATGGCCAAACGCTGCAAATTGTCCAGCAGCCGAACGGCACACAGACCCTCCAACTGGTGCAATTGGTGCCGCAGCGTAGCATGGCGCCGGCGATCACAACGACGACCACAACGGACATGTGCACGACAAGCAGTGGGGCTTCGCTGGCGGATGCAGATGTGCAGCTTTTGGACGATGCCGAAATGGATGATGAGGAGCTAGAAGAGGTGTATGAGCAATTGGATGGCAAGGATCACACGTTCGAAACGATTGTGCTGGACGATGATCAGCAGCAGGATTTTCTAAaggagcaacaacatcaagttCTACTTGACGAGGAGCTCACGCACAGCGACACACAAGAGCAGGAGACCGACGAATACTTTgacgagcagctgctgcatcacGAGGATGGCGTCAAGCACgaggatgacgacgatgacaaTTTCATCATTGAGGAAATACAACTAGATGAAGATATGCTTGACGATGCGGAAGGAGATGTAGATGGGGATGCCATGACGCATGTCGATGATTGCGAGTACATAACCGATGATCAGGATCACGGCCTTGGTGGCGATGTGGATGATGAGCTGCACTATGCCATTATGGATCCGCCCGATGGCGATGTCAGTGCCAGCGATATTGATCAGGCCTTTATCGATGCCgaggcacagcagcagcaagagttGCAggagcaacatcagcagcaacaacaacagcagtccGTGGACATACATAGCATATCGCTGGAAAATGCTGTGGTCGAATTTGATCAGGACACCTTGGTGGCGCCCACGTTGCATGTGAGCAATACGCCCAGTCCCACGCCCAGTTCAGCGAAGCGCGCACGTCGTGGCAACGCGCAAAACCATAGCAATCAACTGGTGGAGACACCCTGCAACCACCAGCACAGTCCACCCACCATAAGCAGTAAGCTAGCCGCATCCAATTCGCGTCAGTTGGTGCAGACGGCCTCGGTGATTGCAGCAGCGGGCGCCGATGATAATTACGAGATAGATGCAAATCTGGTCACGGAATTTATCAGGCAACACACATCGCCGCTGGGCTCTGGTCGTTACATTTGCCATCTGTGCAGCACCGAGTTTCGGCAGTTCAAGGGCTTGCAGAATCACATGCACTCGCACACCAACTGGATACGGGCCAATTGCAAGAAGCAGCCGCAGTGCGAGATCTGCCTGAAGAGCTTCAAGGGGCCGGGCATGCTGCGCATGCACATGAAGACGCACGATGCTGAAACGAGTACCCCATTGTGCAATATATGCAATCGCACATTCAAATCGAAAGCGATACTCTACAGGCACAGGCAGACGCATCAGCAGCGCGCCTATTGCTGTGGCGTGTCCAATTGCCGCAAGAACTTCTCCAATGCGGCCAATCTGCGCTGGCACGTGGAGCGCAAGCATCCGGAATGCGTTGATCCGTTGTACAAGTGCGGCGAATGCTCCACACTCTACGATAACATCGACAATCTGCAGCAGCATGTAGAGAATACGGACCATGccagcagcaatggcagcgaaacacacacaattgtcACCAGCTCAAATGCCGCATTCAGCGGCGCCGTCAGCATTGTCAGCAATGGCACTGACATGTCCAGCATGATTGCTGCTGCACCCAATGCGCTAAGCGGCACAGCTGGGCCGGGTGATACGCATGCCGTGGTCGTTGGCTCCTCGGGCGAGATGTACTTTGTGACGCAGGCGTAG
Protein Sequence: MMDRKKVLELDKICRLCISERKEMRPLFSEKVPEMLMDCTSVRVEPTEGWPDKICVQCVHAVSRNHAFKSLVERSDKELREYIKSLTVRMVMDESLTPQERKQQKLLQKQLKQQQQLEEQQQKLEQQIMQQQQQLQQQQQQQQQQQQQQQSSIFLVQQPHQQQHQQQQQQKPKNKLKPLLRKGTSRQSKKQQDVVQLLPEPAPPPPPPQLVTQQQQQQIQQIQLPTLQPAPAQLMPTTTAQQILLPNGQFITTQIVTPQLAQIIGAQTTTSNATASAQAQFLPQLLQAPNGQTLQIVQQPNGTQTLQLVQLVPQRSMAPAITTTTTTDMCTTSSGASLADADVQLLDDAEMDDEELEEVYEQLDGKDHTFETIVLDDDQQQDFLKEQQHQVLLDEELTHSDTQEQETDEYFDEQLLHHEDGVKHEDDDDDNFIIEEIQLDEDMLDDAEGDVDGDAMTHVDDCEYITDDQDHGLGGDVDDELHYAIMDPPDGDVSASDIDQAFIDAEAQQQQELQEQHQQQQQQQSVDIHSISLENAVVEFDQDTLVAPTLHVSNTPSPTPSSAKRARRGNAQNHSNQLVETPCNHQHSPPTISSKLAASNSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCEICLKSFKGPGMLRMHMKTHDAETSTPLCNICNRTFKSKAILYRHRQTHQQRAYCCGVSNCRKNFSNAANLRWHVERKHPECVDPLYKCGECSTLYDNIDNLQQHVENTDHASSNGSETHTIVTSSNAAFSGAVSIVSNGTDMSSMIAAAPNALSGTAGPGDTHAVVVGSSGEMYFVTQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589145;
90% Identity: iTF_00544819;
80% Identity: -