Basic Information

Insect: Drosophila ezoana
Gene Symbol: BCL11A
Assembly: GCA_035045725.1
Location: JAWNOU010000103.1:2676941-2687041[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.028 2 9.2 2.4 1 23 270 293 270 293 0.95

2 6 1.3e-05 0.00095 19.6 1.1 1 23 746 768 746 768 0.97

3 6 0.013 0.92 10.2 4.7 1 23 774 796 774 796 0.99

4 6 1.2e-06 8.6e-05 22.9 3.2 2 23 1086 1107 1085 1107 0.97

5 6 1.6e-05 0.0011 19.4 3.3 1 23 1113 1135 1113 1135 0.99

6 6 2.9e-05 0.0021 18.6 0.4 1 22 1143 1164 1143 1164 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.028	2	9.2	2.4	1	23	270	293	270	293	0.95
2	6	1.3e-05	0.00095	19.6	1.1	1	23	746	768	746	768	0.97
3	6	0.013	0.92	10.2	4.7	1	23	774	796	774	796	0.99
4	6	1.2e-06	8.6e-05	22.9	3.2	2	23	1086	1107	1085	1107	0.97
5	6	1.6e-05	0.0011	19.4	3.3	1	23	1113	1135	1113	1135	0.99
6	6	2.9e-05	0.0021	18.6	0.4	1	22	1143	1164	1143	1164	0.97

Sequence Information

Coding Sequence: ATGGCCATAAAAGCGGCAACTGCCGAGCAAATTTATGAACTGCAAGTGCAAAAGTGCCATCACTCAGCGGGTGGTGCGGGCGGTGATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATACTCACGTGCGGCGCGTGCCAGAAGACCTTCGCGCTGTCGGACATCGTCCGGTTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGCCGCCCACTGAGCCTGGTCAATCGCCGTCCCTCCATATCGGCGCCCATCACAGGCCGCAACAGCGCAGCGAGCGGCTCTCGCATACACACACCGCCGCCAAGTCCAGCGGATCTGCTGGCCGATGGCGCCAGCAGCACGCCCAAGCGCCTGGTAGATGAGAACGACAATACGACGCCCAAGGCGGACAGCGATGCGCTGACCACAGCCAGCGGCACGCCCCTGGAGGCGCGCAGTCCCAGCCGCGTACAGTCCAAGTCGGAGCAGCCGCCCGCGCCGCATCTGGCGGCGGACTGCACGCACGACGATGACAAGCCAAAGGTCAAGCAGGAGCCCTATGCCGATGACGAGCTGCCCCAAGACGATGACGACCAGCAGCCCgacgaggagcagcagcagcagcagcaggaggagcaacCCCAGCTGGATGCCCAGCTGCTGTCCACGGCGGACGAGTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACAGTGCATACAGAGCCCAGCAATTACACCTGTTCGACCTGCAAGACCCGCTACACATCCGCCTGGCGGCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGTCGGGCAGCGGTGGCGCCACCTTGACTGTGGCCACGCCCGCCGCGCTCAATGCAGCCgcatcggcagcggcagcgaacGCCAGCGTCAGCCCCAATCGCAGCCTCAGTCCATCGGCAGccgcggcagcggcagcagcggccgcagcagcagcagcagctgttggtgtgccgctgccgttgcacGCGCTGATGGCGCAGGCCGTCGCCTCGCAGTCGCAATCGCCGGTGCcaaagcgcagcagcagcaacagcagcgccgccgccgcagcagcagcagcggcgggaGGAGTTGCTTCAGCCAatacgagcagcagcagcaatgcgaGCAGCGGCAATTCGCCGacgcagcaactgttgcagcagcgcgcacagcagcaacagcaacagcagcagcaacaacaacaacagcagcagcagcaacagcagcagcagcagaacatGGCGACGGCCATGGCAGCGGGCATGCGTCATCATCCGCTGCTGGCACCGCCGGAGGCAATGCACGCGAATCCGTTCCAGCTGCTGCGCATGCCGCTGCCGCCCGCGCTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCACTTTTCGGCAGACCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTGAGCGAGCAGTTCCGGCATCATGGCTTCAATctggccgccgccgctgccgccgcccagGCCCAGTTCAATGCCAAcacccaacagcagcagcagcagcagcagcaaccgatCCCTGGCGTTGCTGTCAACGTTCCTAGCGGCATCGAGCAGCGGCCGCCctcaagcaacagcagccagcgcGGCTCTGTGCCACCCGCCGCGTTGCCGCCGCCCTCGCTCAGctcacagcagcaacagcagcagcaacagcagcagcagcaacaacagcagcaacaacagcagcagcagcagcaacagcagcagcaacaggctgCTGCAGTGAGTCCAGCGGGCGCCGCATTGAATCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCGGCCAGCGTGCAGCTGGCGGCGACACCGCGTCCCCATTCCCTGACGCCGCCCGAGCGGAGCACCGAGAAtggcggccagcagcagcacagcctGCAGCTGCCCAGCACGCCACGTTCGGCCAGCACGCCGCCGAGCAAGCCGCATGCCCCAGCAGCAGACTCGGAGCGCAACGAGGCGGAGGCAATGGAGCTGGCGAGCAGCTGCTTCGCGTGCGGCTTCTGCGACAAGAAGTTCCGGTTCGAGAACAATCTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGCCCCGCTGAGGGCCacgacggcggcagcagcagcaatggcggCGACAACAATCAGGACGGCCACGACGGCGGCAGCAATGCCGATTCGCTGGAGACGAACGAGGCGGACAACGACGACGATCCCAATCCGGACGAGTCCGACGACGAGCTCAACGAGGAGGACGTTGACGCGGAGGCCGAGGGTGAGGGTGAGGGCGAGGACGATGATGAGGATGAGCTAGAGGACTGCGAGGATGTCGACTACGAGGCCGAAGATCTCAGTGTCAACAATCGCATCGATGGCAAGAGCCAAAGCCCCAAGACGACTAGCTCCGGCGCCACCTCGCTGGTGGGCGAGCTGATGGACAAATTCGGGCTCTCCAACATAGCCCAATACTCGGAAGCCTACAAGCAGGCCCTGCAGGAGTCCGGACGCAAGGAGGCCGCCGctgtcgccgctgccgctgcagctgccgcggccgtcgacaacaacaatcgcgGCTCCTCTGGACCCGGAGCCGGCGTCGGAGCCGGATCTGGTGCTGGTGGACCCGGTGGCCCTGGTGGCGCTGGCGCCGACAAGCTGAACGGCCTGCCGGTGGCGGCGCTGCGTCTGCGTGACGAGTTCGCCAAGAACTGCAACATGTtccagccgcagccgcaggaTGGAACCGGCCAGGTGCCGCTGTTCAATCCGTTTCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAAATGGACGGCGGCGACTGGTGGGGCATGTCCGCGCTCCATCGCAACGAGGCGCTCTTCGAGAACCTGAAGCTGAAGCCGCTGGGCCTGGGCGGCGCCAACTCGCTGCTGCAGGGGCCGCTGCTGAAGAAGGAGTCGCGGCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCATCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGTGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGATGTCTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTGGTCAACCAGGGCAAagcggcagccgctgccgccaaCGCGGCCAATGCCGTAGCCGCTGCCCAGGCCGCCGCCGCGGCCCAGCAGCTCCAAGCGGCTGCCGCCCAGGcccaacaccagcagcagcagcaacagcagcagcagcagcagcagcaacagttgcccaCGCAATCGCAATTGTCGCCACCTTGCCccatgggcgtggctgtgggcTTTCCACCGCAGTTCGGCGTCGCCGGCGGCCACAATCTGTCGCTGGCGGGCAGCGTGAGCGGCGACAACGATTCGAATGCATCCTCCAGCCTGCCCGCCCACTCCATTTCGCTCAAGGAGGAGGCATGA
Protein Sequence: MAIKAATAEQIYELQVQKCHHSAGGAGGDSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRNSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSDALTTASGTPLEARSPSRVQSKSEQPPAPHLAADCTHDDDKPKVKQEPYADDELPQDDDDQQPDEEQQQQQQEEQPQLDAQLLSTADECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESGSGGATLTVATPAALNAAASAAAANASVSPNRSLSPSAAAAAAAAAAAAAAAVGVPLPLHALMAQAVASQSQSPVPKRSSSNSSAAAAAAAAAGGVASANTSSSSNASSGNSPTQQLLQQRAQQQQQQQQQQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANTQQQQQQQQQPIPGVAVNVPSGIEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQAAAVSPAGAALNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAASVQLAATPRPHSLTPPERSTENGGQQQHSLQLPSTPRSASTPPSKPHAPAADSERNEAEAMELASSCFACGFCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGHDGGSSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPDESDDELNEEDVDAEAEGEGEGEDDDEDELEDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSGPGAGVGAGSGAGGPGGPGGAGADKLNGLPVAALRLRDEFAKNCNMFQPQPQDGTGQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAAQAQHQQQQQQQQQQQQQQLPTQSQLSPPCPMGVAVGFPPQFGVAGGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547608;
90% Identity: -
80% Identity: -