Dezo006150.1
Basic Information
- Insect
- Drosophila ezoana
- Gene Symbol
- -
- Assembly
- GCA_035045725.1
- Location
- JAWNOU010000052.1:4217348-4219580[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.03 2.1 9.1 0.7 2 23 314 336 313 336 0.96 2 10 2.1 1.5e+02 3.3 0.2 6 23 346 363 346 363 0.97 3 10 1.5e-05 0.0011 19.5 0.9 1 23 369 391 369 391 0.98 4 10 0.00052 0.037 14.6 2.4 1 21 404 424 404 427 0.87 5 10 5.6e-05 0.004 17.7 0.7 1 23 435 458 435 458 0.97 6 10 2.7e-05 0.0019 18.7 1.0 3 23 466 487 464 487 0.92 7 10 0.0029 0.21 12.3 0.4 2 23 499 521 498 521 0.97 8 10 0.00087 0.062 13.9 7.0 1 23 528 551 528 551 0.93 9 10 2.5e-06 0.00018 21.9 1.2 1 23 557 579 557 579 0.98 10 10 6.1e-05 0.0043 17.6 1.4 1 23 585 608 585 608 0.97
Sequence Information
- Coding Sequence
- ATGGCAGCATGCGTGCTCTGTTTTGGGTGCTGCAAGAGTGGCGAATCGTATAAGATATTTTCCGAGGCTGGTTCGCGGCTgaacatttgcaaaacaataaacaaacacttTTGGCTCGAGCTGAGCAGTGCAGGGGGCGAGCAGGAGGAAATCTGCCGCCAGTGCTGGGAGTGCGTGAGCAGCTTCAATGAGTTCTACCAACGCGTGTACAATGCCCACCAGGAACGACGCTGCGATGTCAAAAATGTGCCCATCGAATTCTGCGACGAATCGGAAGCAGCCAATCCTCTCGCCTTTGGGGGAGAACTGGATGCCCTGGCCGAAGATTTCTTTGCAACTGGCGATGTCAAGGTAGAGGTGAACGAATTGGAGCCGCTGCCCAAGCTTGAAATGCTCGAGGAGCCCCTAGTGCTAAGCGGCGCATTAAAAACGAGCAGCTTGACGCTCGCCAGTGACTCGGATGGAGACATACCGTTGGCTGAGTTCTTGGACCTTAAAGCACCTGCAAAGCAAGCAGCAGCGAGCGATAAACCAATTGCAGCCAAGGGACGGCAGCTGCGCCGTAGCTCTCGACGTGGACGCCGATCAAAAACGCCGCCAGAATCGCCGCCGACCTGCATGAAGAAGGAATTCGAATCGGAAGAAGAGCATGATAATGATGACAGGGAGTTTGTGGCAGCCGAGGCATTGCTGGGCACTGAGGACAGTGCCAGTTCCAGCGAGAGCAGTGACAGTGACTCCGGCAATAGTTTGCCGGACATTGAGCCGGAAGAACGATATGCAGAAATACCCAAACGTATTGTAGTCAAGCCCAAAAAGTATCGCAAGCGTCCCAAGCCGTTGGTGCCCCCTGTGCGCATGAGCCGGGAGGAGATTGAGAAGCGCAAAGCACAGCAAAACGAATTCGATGAGATTATATTTGACTTTTTCAAAAAGCTGCCATGTCATATGTGCAACCTGCTAGTACCCAACTTCGGCGACATGCGACGCCATCAGCGCATGTCCCACAACATTGAAAGCGGCTTCATAGCCTGCTGTGGTCGCAAGTTTCACATACGCCGGGCTTTGGCTGAGCATGTGCTGGTGCACAAGAATCCAGAGCATTTTATGTGCACACAATGCGGCCGTGTTTTTCAGGACTCGAAAACGCTTGAGACGCACGAGCAAACGCACACGAATCCTCAAGCGGATTCGAAGGATAAGCGTATGTACCAGTGTGACAAGTGTCCCAAATGCTTTACCACAAAGGCTGCTGTCGAATATCACAATGTGTCCAAGCATGTGCCCAAGTCGGATTTCAAATACACCTGCCCCGAGTGCAATAAGAAGGTGCCCACAGAGCGCAAGCTAAAGGAACATCTACGCTATATGCACGATCCAGAGACTGCCATCATCTGCGATAAGTGCGGCAAAACCTTACGCTCTCAGGCTAATCTTAAGAAACACCACGAACTGGAGCATTCTGATAAGCCACGCCCCAAACCCGACCCAGTGCAGTGCGAGATATGCGGCACTTGGCTGCGCCATTTGTCCGGTCTCAAGCAGCACATGAGCACGGTGCACGAACCGCCGGGCGGTGAGCATCGCTGTCACATCTGCGATAAGAAGTCGACCAACTCGCGCGCACTCAAACGCCATATCTATCATAATCATCAGTGCGAAAGAAAGTTCCGCTGCACCATGTGCGAGAAGGCCTTTAAGCGGCCACAGGATTTGAGAGAACACACTTCCACGCACACGGGCGAGGTGTTGTACACCTGTCCCAATTGCCCACAGACGTTCTTTTCAAATGCCAACATGTACAAGCATCGGCAGCGTTTGCATCGTGCCGAATGGGAGGCGGATCGCAAGAAGCCGCTGCCGCCCAACATAATGCAGCAAGCGGTGGGTGCAACAACGGCCATGAAGAAGCGTCAGACCAGCAGCGCCGGGCCAGCGCTATTCACGCAACCCGCTGAGCCCACCGCGGATGCCCCCAAGCAGGAATCACAACTGCAATAG
- Protein Sequence
- MAACVLCFGCCKSGESYKIFSEAGSRLNICKTINKHFWLELSSAGGEQEEICRQCWECVSSFNEFYQRVYNAHQERRCDVKNVPIEFCDESEAANPLAFGGELDALAEDFFATGDVKVEVNELEPLPKLEMLEEPLVLSGALKTSSLTLASDSDGDIPLAEFLDLKAPAKQAAASDKPIAAKGRQLRRSSRRGRRSKTPPESPPTCMKKEFESEEEHDNDDREFVAAEALLGTEDSASSSESSDSDSGNSLPDIEPEERYAEIPKRIVVKPKKYRKRPKPLVPPVRMSREEIEKRKAQQNEFDEIIFDFFKKLPCHMCNLLVPNFGDMRRHQRMSHNIESGFIACCGRKFHIRRALAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHTNPQADSKDKRMYQCDKCPKCFTTKAAVEYHNVSKHVPKSDFKYTCPECNKKVPTERKLKEHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDKPRPKPDPVQCEICGTWLRHLSGLKQHMSTVHEPPGGEHRCHICDKKSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATTAMKKRQTSSAGPALFTQPAEPTADAPKQESQLQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00508523;
- 90% Identity
- iTF_00582434;
- 80% Identity
- -