Basic Information

Insect: Drosophila ezoana
Gene Symbol: Znf516
Assembly: GCA_035045725.1
Location: JAWNOU010000193.1:93613-95370[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00048 0.034 14.8 0.4 1 23 232 255 232 255 0.96

2 8 1.9e-06 0.00014 22.3 1.1 2 23 277 299 276 299 0.93

3 8 0.00015 0.01 16.4 0.3 2 23 326 346 326 346 0.97

4 8 9.7e-06 0.00069 20.1 0.9 1 23 352 374 352 374 0.98

5 8 9.6e-06 0.00068 20.1 0.9 2 23 381 402 380 402 0.97

6 8 4.8e-08 3.4e-06 27.4 0.8 1 23 408 430 408 430 0.98

7 8 0.021 1.5 9.6 0.9 1 21 436 456 436 460 0.87

8 8 0.039 2.8 8.8 0.1 1 23 508 532 508 532 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00048	0.034	14.8	0.4	1	23	232	255	232	255	0.96
2	8	1.9e-06	0.00014	22.3	1.1	2	23	277	299	276	299	0.93
3	8	0.00015	0.01	16.4	0.3	2	23	326	346	326	346	0.97
4	8	9.7e-06	0.00069	20.1	0.9	1	23	352	374	352	374	0.98
5	8	9.6e-06	0.00068	20.1	0.9	2	23	381	402	380	402	0.97
6	8	4.8e-08	3.4e-06	27.4	0.8	1	23	408	430	408	430	0.98
7	8	0.021	1.5	9.6	0.9	1	21	436	456	436	460	0.87
8	8	0.039	2.8	8.8	0.1	1	23	508	532	508	532	0.91

Sequence Information

Coding Sequence: ATGGACAGTAACAAAAATGAGATTCCAATACCAGGTAAAGTTCATACTAATGTTAACGAGCAAACCTGTCGCGTTTGCTTGGAATCTCACGAAACAACATTGAGCCTTCACGATGAAGTTGAGTTTAATGATCTGTATGTTgagctgtggcagctgctagAAAACGTATCCAATTTGAAGtGCACTTGGAACGAACCCAATCTACCCACAAAGCTGTGTCAGAGCTGCACGCGTCGCCTGATCAGCGCCTACGAGTTTATACGAGAAGTAGAAAGGTCCAATCAAACGCTGCAGGAATTATGCAGTAGTAAGAAGCAGGATCAATCGGCTGAGGATCATGTGAATGTGGATGAGTACGAAGAATTACCGCACCAGGAAGTGGACCTGCTACAAATGGAAGAATGCGAATCCGTCATTGAGGTAGAGCTGCCGCCTGAAGCCCCGGCCTATGAGGAAGCGCCGTATGTGGAAGCAACTTATGAAGAATCAACGTTTGAGGAACCAGCCTATGAGGCACCTACATATGAGGAACTGTCTTTTGTGGAACCGCCATCTGAAGAGTTACCCATAAGCGACAACGACCCCAGCGATCTGGTTACTGAGTCGGATGCGGACATAATTTATGATGCCGATCAATCAGAGGATCGTCCCTCGCAGCTAGGAATGCGCCTGGCACATTCACAAAACTTTATGTACAAATGTGCCAGCTGTCCACGCAtttttgccaaaaacaaatcgtTGTTACGCCACTTTGCAACAGCTCACAGCCAAGCGGCTGATGTAGCGGCTCAGGAGCTGGCTAAAGAGCACAGCAGCAGTGGCGCACTGATCTGCGAACATTGTCCGCGCATATTCAAGCGTCAGGATACACTGCGTAGACACATGATTGCATTTCACCCTGAGGTAGTCGCCGCTAGCGGCTATTCAGAAGATGCCATAATGAGCGTACCACCAAAACGTGCAGCCAAGCGGCGCGAATGCCCCCATTGTGGCATAAGCTTTCCTGTCTCCAGCCTGACCATACATATACGTCGTCACACTGGCGAAAATCCATACAAGTGCGATCAGTGCGACAGGGCATTTCCACGCAGTCAAGATCTTAGTCTGCACAAGCGTCAGCACACTGGAGAGCGCCCGAGCGAATGCAAAATATGCGCCAAGAAGTTCATTTCGCAAAACAAGTTGGCACGGCACATGCGTCTGCATACTGGCCATCGACCCTACGCTTGCGATAAGTGCGACAAGAGTTTTGTGCAATCTAACGATCTGAAGATTCATATGCGCCGCCACACGGGCGAACGACCTTACGCGTGCGGCGTTTGTGGCAAAAGCTTTGTTTGTGGCTCTCTTTTAAACATTCATCGCAATCAGAAGAGACACTATGAGACTGTAAGGGAAGGAGCTGATAGCTTCGATCCTGATCCCTATGAAAATAGTCGCGTAAATAAGCGTCGTGCCGAGGACATTGAACGAATGCGACTGCTGCGAGAGAGCGACACGCACACAACTATTCTGCGGCCATACAACTGCGGCGTGTGTGGAGATAACTTTAAGAGCGGAGCCCTACTCACAATTCATCGCAATAAAATGGCCCACTATGAGATGGGCAACGTGGACTACGGTGATCCCTACGAGCAAAGatacaagcagcagcagcaggcgcagcagctcAAAATCGTGCAGAACGAAGATTAG
Protein Sequence: MDSNKNEIPIPGKVHTNVNEQTCRVCLESHETTLSLHDEVEFNDLYVELWQLLENVSNLKCTWNEPNLPTKLCQSCTRRLISAYEFIREVERSNQTLQELCSSKKQDQSAEDHVNVDEYEELPHQEVDLLQMEECESVIEVELPPEAPAYEEAPYVEATYEESTFEEPAYEAPTYEELSFVEPPSEELPISDNDPSDLVTESDADIIYDADQSEDRPSQLGMRLAHSQNFMYKCASCPRIFAKNKSLLRHFATAHSQAADVAAQELAKEHSSSGALICEHCPRIFKRQDTLRRHMIAFHPEVVAASGYSEDAIMSVPPKRAAKRRECPHCGISFPVSSLTIHIRRHTGENPYKCDQCDRAFPRSQDLSLHKRQHTGERPSECKICAKKFISQNKLARHMRLHTGHRPYACDKCDKSFVQSNDLKIHMRRHTGERPYACGVCGKSFVCGSLLNIHRNQKRHYETVREGADSFDPDPYENSRVNKRRAEDIERMRLLRESDTHTTILRPYNCGVCGDNFKSGALLTIHRNKMAHYEMGNVDYGDPYEQRYKQQQQAQQLKIVQNED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534745;
90% Identity: iTF_00534745;
80% Identity: -