Basic Information

Insect: Drosophila ezoana
Gene Symbol: -
Assembly: GCA_035045725.1
Location: JAWNOU010000193.1:712409-717035[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0026 0.19 12.4 2.1 1 23 224 246 224 246 0.97

2 26 0.034 2.4 8.9 1.9 1 23 252 274 252 274 0.97

3 26 3.8 2.7e+02 2.5 2.7 3 20 307 324 305 327 0.93

4 26 0.0013 0.095 13.4 1.2 1 23 404 427 404 427 0.92

5 26 8.7 6.2e+02 1.4 3.2 2 23 438 461 437 461 0.92

6 26 0.12 8.5 7.2 0.5 1 20 467 486 467 488 0.93

7 26 0.83 59 4.6 2.0 1 23 506 528 506 528 0.98

8 26 0.01 0.74 10.6 2.5 1 23 608 631 608 631 0.94

9 26 0.003 0.22 12.2 0.2 1 22 638 659 638 659 0.93

10 26 3.1 2.2e+02 2.8 5.6 1 23 668 691 668 691 0.94

11 26 0.0011 0.081 13.6 0.2 2 23 719 740 718 740 0.97

12 26 0.00017 0.012 16.2 4.2 1 23 748 770 748 770 0.99

13 26 0.059 4.2 8.2 1.7 1 23 916 939 916 939 0.95

14 26 0.0067 0.48 11.1 1.0 2 22 947 967 947 967 0.96

15 26 0.15 11 6.9 0.5 1 23 976 999 976 999 0.91

16 26 1.2e-05 0.00083 19.8 1.9 1 23 1024 1046 1024 1046 0.97

17 26 0.00025 0.018 15.6 1.1 1 23 1053 1075 1053 1075 0.98

18 26 0.018 1.3 9.8 0.0 2 21 1102 1121 1101 1122 0.93

19 26 0.043 3 8.6 4.0 1 23 1167 1190 1167 1190 0.96

20 26 1.3 95 3.9 0.5 1 23 1227 1250 1227 1250 0.93

21 26 0.0043 0.3 11.8 1.4 1 23 1275 1298 1275 1298 0.97

22 26 1.5e-05 0.001 19.5 0.1 2 23 1322 1343 1321 1343 0.95

23 26 5e-05 0.0035 17.9 2.9 1 23 1349 1371 1349 1371 0.99

24 26 2.4e-06 0.00017 22.0 2.0 1 23 1377 1399 1377 1399 0.97

25 26 6.2e-08 4.4e-06 27.0 2.4 1 23 1405 1427 1405 1427 0.99

26 26 0.00074 0.053 14.2 0.3 1 21 1433 1453 1433 1457 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0026	0.19	12.4	2.1	1	23	224	246	224	246	0.97
2	26	0.034	2.4	8.9	1.9	1	23	252	274	252	274	0.97
3	26	3.8	2.7e+02	2.5	2.7	3	20	307	324	305	327	0.93
4	26	0.0013	0.095	13.4	1.2	1	23	404	427	404	427	0.92
5	26	8.7	6.2e+02	1.4	3.2	2	23	438	461	437	461	0.92
6	26	0.12	8.5	7.2	0.5	1	20	467	486	467	488	0.93
7	26	0.83	59	4.6	2.0	1	23	506	528	506	528	0.98
8	26	0.01	0.74	10.6	2.5	1	23	608	631	608	631	0.94
9	26	0.003	0.22	12.2	0.2	1	22	638	659	638	659	0.93
10	26	3.1	2.2e+02	2.8	5.6	1	23	668	691	668	691	0.94
11	26	0.0011	0.081	13.6	0.2	2	23	719	740	718	740	0.97
12	26	0.00017	0.012	16.2	4.2	1	23	748	770	748	770	0.99
13	26	0.059	4.2	8.2	1.7	1	23	916	939	916	939	0.95
14	26	0.0067	0.48	11.1	1.0	2	22	947	967	947	967	0.96
15	26	0.15	11	6.9	0.5	1	23	976	999	976	999	0.91
16	26	1.2e-05	0.00083	19.8	1.9	1	23	1024	1046	1024	1046	0.97
17	26	0.00025	0.018	15.6	1.1	1	23	1053	1075	1053	1075	0.98
18	26	0.018	1.3	9.8	0.0	2	21	1102	1121	1101	1122	0.93
19	26	0.043	3	8.6	4.0	1	23	1167	1190	1167	1190	0.96
20	26	1.3	95	3.9	0.5	1	23	1227	1250	1227	1250	0.93
21	26	0.0043	0.3	11.8	1.4	1	23	1275	1298	1275	1298	0.97
22	26	1.5e-05	0.001	19.5	0.1	2	23	1322	1343	1321	1343	0.95
23	26	5e-05	0.0035	17.9	2.9	1	23	1349	1371	1349	1371	0.99
24	26	2.4e-06	0.00017	22.0	2.0	1	23	1377	1399	1377	1399	0.97
25	26	6.2e-08	4.4e-06	27.0	2.4	1	23	1405	1427	1405	1427	0.99
26	26	0.00074	0.053	14.2	0.3	1	21	1433	1453	1433	1457	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACGAATATTTGTCGCACATGCGCGCTACAGGATGACAGCTTGCTCCCGCTAGCAACGCGCactaataaatatgcaaataaaagttttaGCGACATATTGCACGAATTGACACAGAATGATCCTTTGCAGGACCATACGGATGATGGCTTGCCTCAGTATTTGTGTGGCGAATGCCTGCACAAGCTAGAAGCTGCCTATGCTTTTGTGTTGCAGGCGCGGCAGGCGCAggagcaactgttgctgcagctacGCAAAGGTTCGCAAAGGCAGTGCTTGGAGGAGATGCCCATAGACATCAGCATGCAGGCCATTAAAAACGAAACGAACGTTGACGTAGATTCGGAGCCAAACAGAAAAACCAAAAGCGAGTCGCTACTGGAAGATGCGGGAGAGGTCGAAGAACCAGAGATTGCTGCAGTGTCTGGTCCAGCCTTAAAATGGCAGCCGGAAAGCGAAAGCGACAATAATGAGGCGGCTGTTGATGAGCAGGACAGGGACGTCAAGCCCAAGCAATTGCGGCGCAGCTTACGGAAAGCCAAACATGGTATAGTCAGCGAAAATGAAGCCTCTTTTGCTAATACGAACCCCTTAACTGTCAGGCGTCGTCGCGGACGTCCCGCGCGTCATCCCAAAAAAGGAAACATCAATGAGGAGGGCCGACATACGTGCGAGGTGTGCGGGAAGACATTTTCGTGGCACCGCGACATGGTACGCCACGCCCGCATACACTTCGAGCAGGCGGCCTACGTGTGCGACAGCTGTGGCAAGAGTTTTTTGCGCAAGGACAAGTATATGTTTCATCTGCGTTCGCACGAGAAGCGTGCAGCCAAATGGCAGGCGTTGCAGCTAAGTAGTGAATGGCGCTTTGCAGAGCGCCTCTACAGCTCGGGCCGGCTCAAGCATATGATCTGCAAGCTGTGCGGCTTGAAGTGCCAGCGCATTCGGGAATTACGCGATCATTTGGCGTGCCATGCCAGCATTGAAACGTTGTCTAAATTGAGTATGGAGAGTGATGTGGTCAAAGAGCAGTTTGtcaacgagcagcagcaattggaCTTGGTACAGATTAAGCAACAGGTGTGCGCTGACATTGCCAAGGGACGTGAGCTGCTGGACAACTATTGCGCTGTGGTCAATGCGTATGGTTATGAGCTTTGCCTCAGCGACTCGGATGAGGAGCTAGCTGACTTGACGCCACAGTACCGGTGTCTGCCATGCAACACCACCTTTACGCGCAAATATCTCCTCATGCGCCACACTCTGGAGGAGCACACGCATTCGGAAGCGGATGTACCCTGGCAACGTTGTAATGCTTGTCAAATTGGCTTTGTGTGCGCCAAGCTGCTGGAGCAGCATCAACGCACGCAGTGCCACAATAAACTAAAGCGCTATAGCTGCCCCGATTGTCCAGGAAAATTCATTTGGAAGCAGAATTTGAAGCAGCATGCGTGCTCCCAACGCAGCGGGGTGCAAAaggagcaacagcatcaaAAGGTCGCCCATCAATTCCAATGTTGTCTCTGCGACGCCCAACTACACAGCATGGGAGGATTACGCTCTCATTTACTCACCCATCGCGATGGACGCAGCGGCATAGATCCGGAGAAGCGGTCTGCCTTCTTTCGCACCTATTATCCCGATGGCTTTGCCTGCAGCTTGTCAGAGCTGAGCGCACGCATTGCCGGCGACTTTGAGGCAGAGGATTATGGACGCTACTTCAATGCCAGCACTAGCAGTGGGCAGGAGCTGGATTTCTTTGACTCGGAGACAGATTTCAGTGGTGAGGAGCAGTTGAGCTCTGTCGATGCGTTGCATATATGCTCACTGTGTGGCGAGACCACAATACGCCGGACCCAACTGCTtgagcatcagcagcatcagcatagTGAGGCCAGGCTGCCGCATGCCTGCGAGGACTGCAACATGAGCTTTGTAGCCGATTCCTTACTGCAACGACATCGCCGAAGTATTTGTGCCAAGGGGCATGCCAAGTATCATTGCCAGTTTTGCAGCCAGCGTTTTTACTGGCACTCTAACTATGAGCGGCATTTGGAGCTGCAGCATGAGAAGGAGGATAAAACAGAGGTTACCGAAGAGCAGGAGCCCAGATCAAGAAGCAAGCGCCATCCAACAGCAGCCAAGCTGCAGTGTGGCGAGTGCGAAAAGGTCTTCATCTGGCCCAAGGATCTGACGCGTCACAAGCGCCTGCATCAGCCGCAGGCGTTGGCTCAGTACGAATGTGTTCACTGTGCGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGCGTGCACGGTGAACAGCAGCTTACCAGTGATCAACCGTCATCATCGTCTGTTCTGCAGCACATGCCGGTTGTGTTGACCCAACTTTGCCGGCCCAATGGTTGCAAGCAGATTCAGTGCATGATTTGCTTTTCGCAGCACACAAAGATCGCCGATCTGCGTGCGCATTTACTCAATCATCAGTTTGCGGTGATGTTTGCGGAGGATCGTGGTAAGTCGGCGAGCATTGCAAGCATTTCACGTGCTCTATATCCAGAGCTAGCCACGCCGCTGGATCAGCAACAGCTGGTCAGGCGCATTCAAAGCGATGTGGCCAAGGGCCTTGAACTGGAAAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCTTGGACAGCAGCGAGACTGAAACAGATTCTGACTCTGCCGAGACAGTTGGAGGCAGCAACGGGCGTCTCTACAGCTGTGAGCTGTGCCAGCTGAAGGTGCAGCGCAAGCATCAGCTCTACGCCCATCAGCTGGAGCAGCATAAGTGGCAGCAGGCGACGCGTGTTTGCACCCATTGCCAGGCCAGATTCGTGaatgagcagctgctggagcaTCATTATCGCACTCTCTGCCGAAACGCGCAGCGGCGTTTTTTATGTCGCAAATGCCCATTGCGCTTTCGCTGGCGCGAGAATCTAAAGCTGCACACGGATGTAGCGCACCAAGAGGCAAGTGAAGAGCATTTGAACTTGGGCATTCAAGTGAACGGCTCACATCAGCTGCCTATTGTTAGCTATGACTGCACTGAATGCAATCGCagctttaaaatgcaaaaggaTCTCACCAGGCACACCCTGATGCATGCCCAAGAATCGAGCATTTACCGTTGTCGCTGGTGTGCACGACGTTTCTATCGCCGGGCCAATCTTCTGCAGCATATCGAGCGTCACGGCATTAGTGCCGAGCAGCTGCCCTATGCGGAGGCGCTGCTCAATGCCAGCCGGCATCCGCATGGCCAGAAGTGCATCCAGTGCAAGGTGTGTAATATATCCTACCCCACCATTGCCGCACTGCGCGCCCATCTGCATTCTGCGCCAGGAGGCACACATCATGAACTTGGCTCGATGCTCAACTACTCTATAACCAACCAGCTGGGATacgagctgcagctggacgACTCGGAAACAGATGAGGAGGCCAAGCCGCCgggcacacccacacactacACATGCGGTATGTGCCAACTGCGCTGTGTGCGCAAGTTTGAgcttcatcagcatcaacaggcCATGCATCGACTGGAGCGCATAAGCGAGGGTTGCGatctttgcatatttaaaagcGTCTCTCCTGATCTTATTAACTATCATCGTCGTGCGCTGTGTGACAACACAGAGAAAAAGTTCAAATGCATCAAGTGCGGCTACAAGTTTATGTGGGAGGCGAATCTGCTGCAGCACGTAAAGCTGCAGCACCCCAGTAGCGAGCTGCAGCAGGAAGTGACTTCCATGCTCGCAACGGAAACTTCCAGTACTGAGTGCCAGATCTTTCAGTGCGGTCAGTGTCCTAGTAAATACAATCGCAAGGATCGTCTCACAGCGCACGTAAAAAAATATCATTCAGCAGAAACTAGCTCAAAGGGTGCCCCAACAAAGACTGCAACAGGCGCCAAGCAGCAGAAAAGTTTTCTCTGTGCCTTTTGCGGCAAGGCGGTTAGTTCCTCATCCAATCTGATCATACACATACGTCGGCATACCGGCGAGAAGCCTTTCAAGTGCGACTACTGCGACATGGCGTTTCCACGGTCCTCCGATCTGCAGTGCCATCGACGCACCCATACGGGCGAGCGGCCGCATGTTTGCACTGTTTGTCAGAAGGGTTTCGCGCGCTCCtacaagctgcagcagcacatgCGCATCCACAATGGCGAACGCCCCTACAAATGCACTTATTGTGATAAAAGCTTCACCCAGTCGAATGACCTGACGCTGCACATACGGCGGCACACGGGCGAGCGTCCCTATCAGTGCAACACGTGCGGCGAGCGTTTTATTCAGGGCACAGCGCTCAAAAATCATCGACTACAGAATGGACATTACGAGACGGAAACAGACCAAGTAAAAGATGTCTAA
Protein Sequence: MLPTNICRTCALQDDSLLPLATRTNKYANKSFSDILHELTQNDPLQDHTDDGLPQYLCGECLHKLEAAYAFVLQARQAQEQLLLQLRKGSQRQCLEEMPIDISMQAIKNETNVDVDSEPNRKTKSESLLEDAGEVEEPEIAAVSGPALKWQPESESDNNEAAVDEQDRDVKPKQLRRSLRKAKHGIVSENEASFANTNPLTVRRRRGRPARHPKKGNINEEGRHTCEVCGKTFSWHRDMVRHARIHFEQAAYVCDSCGKSFLRKDKYMFHLRSHEKRAAKWQALQLSSEWRFAERLYSSGRLKHMICKLCGLKCQRIRELRDHLACHASIETLSKLSMESDVVKEQFVNEQQQLDLVQIKQQVCADIAKGRELLDNYCAVVNAYGYELCLSDSDEELADLTPQYRCLPCNTTFTRKYLLMRHTLEEHTHSEADVPWQRCNACQIGFVCAKLLEQHQRTQCHNKLKRYSCPDCPGKFIWKQNLKQHACSQRSGVQKEQQHQKVAHQFQCCLCDAQLHSMGGLRSHLLTHRDGRSGIDPEKRSAFFRTYYPDGFACSLSELSARIAGDFEAEDYGRYFNASTSSGQELDFFDSETDFSGEEQLSSVDALHICSLCGETTIRRTQLLEHQQHQHSEARLPHACEDCNMSFVADSLLQRHRRSICAKGHAKYHCQFCSQRFYWHSNYERHLELQHEKEDKTEVTEEQEPRSRSKRHPTAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYECVHCARKFHRKDGLKSHMRVHGEQQLTSDQPSSSSVLQHMPVVLTQLCRPNGCKQIQCMICFSQHTKIADLRAHLLNHQFAVMFAEDRGKSASIASISRALYPELATPLDQQQLVRRIQSDVAKGLELERFISITNEAGIELSLDSSETETDSDSAETVGGSNGRLYSCELCQLKVQRKHQLYAHQLEQHKWQQATRVCTHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRENLKLHTDVAHQEASEEHLNLGIQVNGSHQLPIVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRRANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNISYPTIAALRAHLHSAPGGTHHELGSMLNYSITNQLGYELQLDDSETDEEAKPPGTPTHYTCGMCQLRCVRKFELHQHQQAMHRLERISEGCDLCIFKSVSPDLINYHRRALCDNTEKKFKCIKCGYKFMWEANLLQHVKLQHPSSELQQEVTSMLATETSSTECQIFQCGQCPSKYNRKDRLTAHVKKYHSAETSSKGAPTKTATGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYETETDQVKDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00563306;
90% Identity: iTF_00551040;
80% Identity: -