Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:4110668-4122933[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00068 0.043 14.0 0.6 2 23 244 266 243 266 0.94

2 10 0.011 0.68 10.2 4.6 2 23 380 402 380 402 0.91

3 10 0.0053 0.34 11.1 2.3 3 23 477 498 475 498 0.94

4 10 0.57 36 4.8 2.3 1 19 598 616 598 621 0.93

5 10 0.012 0.78 10.0 0.2 2 23 732 754 731 754 0.96

6 10 0.00069 0.044 13.9 0.3 2 23 804 826 803 826 0.92

7 10 0.0083 0.53 10.5 3.6 2 23 877 899 876 899 0.96

8 10 0.082 5.2 7.4 4.2 2 23 913 935 912 935 0.92

9 10 0.0017 0.11 12.7 0.7 2 23 998 1020 998 1020 0.95

10 10 0.038 2.4 8.5 0.6 1 23 1114 1136 1114 1136 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00068	0.043	14.0	0.6	2	23	244	266	243	266	0.94
2	10	0.011	0.68	10.2	4.6	2	23	380	402	380	402	0.91
3	10	0.0053	0.34	11.1	2.3	3	23	477	498	475	498	0.94
4	10	0.57	36	4.8	2.3	1	19	598	616	598	621	0.93
5	10	0.012	0.78	10.0	0.2	2	23	732	754	731	754	0.96
6	10	0.00069	0.044	13.9	0.3	2	23	804	826	803	826	0.92
7	10	0.0083	0.53	10.5	3.6	2	23	877	899	876	899	0.96
8	10	0.082	5.2	7.4	4.2	2	23	913	935	912	935	0.92
9	10	0.0017	0.11	12.7	0.7	2	23	998	1020	998	1020	0.95
10	10	0.038	2.4	8.5	0.6	1	23	1114	1136	1114	1136	0.99

Sequence Information

Coding Sequence: ATGATAATATCATCCAAAATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAGGACACTGCTCTCTCCGACGTCTCCAACTCATCGACACTCAACACGAACAGGAACAAccacaccagcagcagcaacagcaacaatccACATGAAGCCACAGGAGCAACACCCACAGCCACAACAGCCACATCTAGAGCAGCAAcaggaggtggaggtggagtGGAAGGCACTTCACCCACCGCACACTTGGTCAAGGCAATGGAGCTGGAACTGGAGCCACAGCCAGCGGGAAGCGGCACAAATGAGGCGGACCAATTGGAGGAGTCAGAGGAGGGGCCCAAGGATGCTGAGGAGGAGGCGGGGGATGCCAACATGGCCACCATGGCGGCAGCCATGCAGCTGCAGATCCTGGAGGCCCTCAGTGATGCGGCCAAAAAGCGTCGCAAACAGCACAATCCCAGCCGTTTGGAGGCTCTCAATTTGAGTGGAGAATCCGGTGGTGAAGTGGGTCAAAAGAGAACTGACTCCTCCACCGTGGACTATGAAGAGAAATTGTCTAAGATGTTCCTTCCAAAGTCCATTGAACAGCTGAAGGAGACCTTCGAaatgctgcagcagcagaaacaacagGAGGAGCAAccagaaacggaaacggaagtggaaACAGATGCCATGGCAAACATATCAGAACCCGCCAAGCAGCGCGAGAATCCCTATCACACATACTGCAAGCAGTGCGGTGAAAGCTTCGAGACCGAGTTCAAGTTGAGCCTGCACATGTTGCAGGATCATGGCGAGGATAGGTCGGGTGAACAGGATCCCGCTGACTTCTTGGCCTCCATCAAGGTGAAACTGGAGCGTGCCGACATTCCCAGTCCGCAGCAGGAACAGAATCTGCAACAGGATCTTACCAATGGGCATGGCAAGGACTTGGAGCGAGAGCAGGAGCACTGGTTCCAGGCCATGCAGGCCCAGCATCATCCGCATGGTCCGCAAATGCCGCCTGCCTTTCCCTTTCCACCGGAGGCAGCCTTGGGTCCAGCTGGATATTTACCTCTACTTGGCATGTCCGGATTTCCGGGCGTAGATGGCCTGAATCGTCCTCCCTTGAGGATCTTCAATCCCGAGGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAGTACTTCCTCAAGACGCACAAGGCCAATAAGCATGGCATCTTCGATCCCGTCGGCGAATCGAGTACCACCAACCCTTCCAGTCaccacaacaataacaacaacaatatcaCCAGCAGTAACAATAATAACAGTGGTCACCCCAATCCCAGTATGAGTTCCATGAGTCAAATGTTCCAGTTGCAGAGGGAAGCCCAGGTGGCGAAGCAGGATTCCACCCCAGTCGGTAGTTCATCGAATCCCGTGGCCTCGGTACATTGTGACATCTGTTCCAAGCGATTCACCAATATCTTCGCCATGCGTCGTCATCGGGCCAAGCAGCATGATGCACAACCAGGTACCCAGGATTCACCCAACTCTCAGACTCCCATGCAATCCCAATCCCTTCGCGGTAGTCCCAATGAAGCACCTCAACCGGCTATCAAGCAGGAAATGTCACAAGAATCAGAGGTTAAGCCGTATCAATTACCCGAGGGTTTCCGCGAGGACTTCACCCTGGAGCAGGAGGAGCTGAGCTTTGTACCACCGCCCAGAAAGTTGCCCTCTCACCTCCATCAGCAGGCTAAAGATTCAAACTTCAACCCTGACAAACTGCGTCGTCTAGGCGTCCAGTTTCCCGACTTTTTCTGTGAACTGTGCTACCGGGAGTATGCCAATCGGTACTTCCTGCGTACCCACAAGTGGAAGCGTCATGGTCTCTTTGTCCCACCCGAAGACGTGGCACCACAACCAGGCGGCAAAGATGAAGCCCAGTTGGCCAGTGCCTGGCCCTTTATGCCACTGAATCTAATGCTGGCCAAGGCAGCAGCTGCCACTATGGATCAGCAGGATCAGGAACGTGACCCGGAATTGGATGCAGAGTCGGAACAGCCCAGCAAGAGGATCAAATTGGAGCAGGAACAGACACCGCCTGAGGGTTACGATGAGGATAAACTGAATGGTTCGGTAGTGGGCCTGCAGAATCTCCAGAAACTGCAGTCGATGTTGCAGCAACTTAACGACATCAATGGCAAACGCCCGCTGCCCTGTCATCTTTGTGGCCAGGAACAGGAGAATCAGTATGCCCTAAGAGCTCATCTCATGACCGAGCATGCTGGCCAGATGCAACTGCCCATGCCCATACCAATTCCTCTGCCCGATCAGCAGGCTCCACATCCCATGGCCAGTTTGTATCATGCACAAGGGAATCCCCAAACTCCACCGGCACCAGGAGCCAGATCCCCTTCAGGTGGTGATCTCCGCTGTCAGCAGTGCGATCGGGATTTCGTCACATCCCAGGAATTTAAGCAACATATCGCCGAGGTGCACTTGGGCAGGAACGGCGGATTAGGTGGAAGTCCCCTCCGCGACGGTTTCTTCACGCCCGAACGACCAGTGGCACCGTCAGCGGGCGGTCCTGGAGCACAAGTTGCTCCGCCAGGAAATCGTCCGGCTTATACCCTTACACCCACGAGCAGCTACTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTATTTCATGAAGACGCACATGCAACGGATGCACGGCATTGAGATAGAGAATGGCGCCCAAATCGGTGGAGTGGTATGCAACATTTGCAACAAGGAGCTGTGCAGCAAGTACTTCTTGCGGGTGCACAAACACAACACCCATGGCATCATCGAGGAGGGATCCCCATTGCCGCAGCCGAGGGGCCAGAATGGAGTCAAGATGGACGCAgcggccgcagcagcagcggctgcaACCTCGCAGCCACCACCGCAGCAGGATCAGGAACTCAATGTCTCACCACCCACAGTGGAGGGCAGTGCCAGCAGTTCATCCAGCGCCCCACACGAGGTATGTCCCCTGTGCTCTCGCCAATTCCGAAGCTTCAAGTGGCTGCGATCCCATCTGATGAACGAACATGGAACCGCCGGAGTGGAACGCCTCCGGGAAATGGACACAACTCAATCTTCGACACGCAGCAAGCCCAACAGTCCCACGCTCAAGATTCCCAACGGCAGTGGCAGTAACCCAACTGCAGCGGGTGCAGGAGCTGGAAATACCGCTCCAAATCTCGCCCAGGCCCTGCAGAACCTCAATGCCCAGCATCTCTTTGGGcaaatgcaacagcagcagatgcCCAAGATGCCTCCACTTCCGCTACCCGGAATGTTTGGTGAACAGGGATCTAGGTTCAAGGAGTACCAGTGTTCACTGTGCCCCTTCACCACGCCCTACTACGCCTTCTTATTCATCCATGAGCGTTCCCACGCGTTGCTCAACAATGGAGGCGAAGGCATGGAATTGCCTATGGAGACGCCACCACCACAACCCTCAAGGAATTCGGGAAAATCGCGCAGCAAATCTAGCAAGGCGGTGGTACCACCTCCTGCCATTAAATCCGAAGATCCGGAGACTCCATTAGAGCCCACCAACCTCAGCACCTCAGCACCCAAGGCCGCGGCCCACTCACCAACAACTGGAGCTGGATCTCCGCCCGTCTACTCCCCCAAGGCAACCAGCTCAACTTCACCGAAGATTCAACGCCGTCGATCCACCTCGAAACCTCCAACCACGCCCAATGGACTGGGAAGCGGTAACGGCAATGGAAACCATCGATCGGCGGCCACATCACCCTTCGAGGGCTGTGGGGAGCTGGCCAACGGAAGTGGTAAGCCGGCCAGCTATGCGCAACCGGATCGGGCAGAGGAAGCATATCAGATGCAGGCCTTCCACCTGCAGCCCGCCGATGCTGACTCGGAAATGCAGTTCGCTCCTGCCCTGGTCTACCTGCCCGTTAGGGTACGGGCCTCGGAGTCGGCCACGCTCAGCTTCCGGCTCACACCGGCCTAA
Protein Sequence: MIISSKMAASIYATPPPDLSSEDTALSDVSNSSTLNTNRNNHTSSSNSNNPHEATGATPTATTATSRAATGGGGGVEGTSPTAHLVKAMELELEPQPAGSGTNEADQLEESEEGPKDAEEEAGDANMATMAAAMQLQILEALSDAAKKRRKQHNPSRLEALNLSGESGGEVGQKRTDSSTVDYEEKLSKMFLPKSIEQLKETFEMLQQQKQQEEQPETETEVETDAMANISEPAKQRENPYHTYCKQCGESFETEFKLSLHMLQDHGEDRSGEQDPADFLASIKVKLERADIPSPQQEQNLQQDLTNGHGKDLEREQEHWFQAMQAQHHPHGPQMPPAFPFPPEAALGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGESSTTNPSSHHNNNNNNITSSNNNNSGHPNPSMSSMSQMFQLQREAQVAKQDSTPVGSSSNPVASVHCDICSKRFTNIFAMRRHRAKQHDAQPGTQDSPNSQTPMQSQSLRGSPNEAPQPAIKQEMSQESEVKPYQLPEGFREDFTLEQEELSFVPPPRKLPSHLHQQAKDSNFNPDKLRRLGVQFPDFFCELCYREYANRYFLRTHKWKRHGLFVPPEDVAPQPGGKDEAQLASAWPFMPLNLMLAKAAAATMDQQDQERDPELDAESEQPSKRIKLEQEQTPPEGYDEDKLNGSVVGLQNLQKLQSMLQQLNDINGKRPLPCHLCGQEQENQYALRAHLMTEHAGQMQLPMPIPIPLPDQQAPHPMASLYHAQGNPQTPPAPGARSPSGGDLRCQQCDRDFVTSQEFKQHIAEVHLGRNGGLGGSPLRDGFFTPERPVAPSAGGPGAQVAPPGNRPAYTLTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKMDAAAAAAAAATSQPPPQQDQELNVSPPTVEGSASSSSSAPHEVCPLCSRQFRSFKWLRSHLMNEHGTAGVERLREMDTTQSSTRSKPNSPTLKIPNGSGSNPTAAGAGAGNTAPNLAQALQNLNAQHLFGQMQQQQMPKMPPLPLPGMFGEQGSRFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGEGMELPMETPPPQPSRNSGKSRSKSSKAVVPPPAIKSEDPETPLEPTNLSTSAPKAAAHSPTTGAGSPPVYSPKATSSTSPKIQRRRSTSKPPTTPNGLGSGNGNGNHRSAATSPFEGCGELANGSGKPASYAQPDRAEEAYQMQAFHLQPADADSEMQFAPALVYLPVRVRASESATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512293;
90% Identity: iTF_00504958;
80% Identity: -