Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:2231574-2265747[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.015 0.94 9.7 2.3 1 23 1401 1423 1401 1424 0.95

2 8 9.4e-05 0.006 16.6 0.0 1 23 1429 1452 1429 1452 0.98

3 8 0.079 5 7.4 2.7 1 23 1732 1755 1732 1755 0.95

4 8 0.00047 0.03 14.5 2.1 1 23 1763 1785 1763 1785 0.98

5 8 4.8e-05 0.0031 17.6 0.2 1 23 1792 1815 1792 1815 0.97

6 8 1.8e-05 0.0011 18.9 1.4 1 23 1821 1843 1821 1843 0.97

7 8 1.4e-06 9e-05 22.4 1.9 1 23 1848 1870 1848 1870 0.99

8 8 0.00073 0.046 13.8 3.4 1 23 1875 1897 1875 1897 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.015	0.94	9.7	2.3	1	23	1401	1423	1401	1424	0.95
2	8	9.4e-05	0.006	16.6	0.0	1	23	1429	1452	1429	1452	0.98
3	8	0.079	5	7.4	2.7	1	23	1732	1755	1732	1755	0.95
4	8	0.00047	0.03	14.5	2.1	1	23	1763	1785	1763	1785	0.98
5	8	4.8e-05	0.0031	17.6	0.2	1	23	1792	1815	1792	1815	0.97
6	8	1.8e-05	0.0011	18.9	1.4	1	23	1821	1843	1821	1843	0.97
7	8	1.4e-06	9e-05	22.4	1.9	1	23	1848	1870	1848	1870	0.99
8	8	0.00073	0.046	13.8	3.4	1	23	1875	1897	1875	1897	0.99

Sequence Information

Coding Sequence: aTGAGTGCCACACGAAGAAGACGTAGCAGTTTCTTCTGCGCGAATTCAACACtatcagcaacaacagaaacaacaacaacaacaacaacaatgaaagCGACTGAGGTAAAAGAGAAAGAAGTCAGTGCAACAGCTGAAGTTGCAATTACACATGCACCAGCCAAAGAGAAACTTTCTCTGCCGTCCGCTGATGAGGATTTACTGAATATGCCACGAatttgccgctgctgttgcaaaCGGGATTTGGAATTACTCGGCTTATTCGAGGCGAGCCAACCAACATTGGCCAACACATCAGCATCGAACAAATCATCGGGAACATTAGCAAAAACATGTGCGACAGAAGCAGAAACCGAAACTCGAGAGACATTGTCCGCAAATCCAGTAAATCCAGGGACTAAAGCTACATCATCTCCATCAGAAGCAgtaacaccaacagcaacaacaccaactACAGGAACAGAAACGGCAACGGCTACAACGTCGTCCGCATTTTCGACCACACCCTCCGCATCTAcattcacatccacatccacatccacatcctccACATCTCCCGTGAGGCGTCGGACCACTTTTGCCACCACAATGGCCACTGCTCCGCGTGGACGTAGCAGCGATAATGCCGTCGACTACACCCTCAGCGGAGCCCACAGCAGCATGGACATTGTCCTCGAGGAGATGACCATTTGGATGCTCAATATAAATCGCGACGATGGACTGCCGCAAGAAATCTGCCGGCAGTGCATGGCCCAGTTTTTGATGGTGGCCAAGTTCCGGCGGAAATGTGTACGGATGCAGCAGCGCCTGCAGGACTTTGCCCAGGAGATATCCGACCGCCAGACGGCCAGACAGGCCAAGCGTCAGCAAAAAGACCAAAAGAAGAGTCAGCACTATAGACAGGAGGTGTCCACCAACCGAGAGCAATCCGTGCGAAAACGCCGTATGGTATCGGAATCGGAAGAAGAATTCACCGGTGAAGCAGCTGTTGCAGTCAAACAGGTGCGAACGGAATCAAAGGATTTGCCACCGCCCAAATCAAGTCCCGTGCAACAACGACTACGTAAGTTACGAACCTTCTCCATCGGCTGTGTAATGGATGCCAGCAGTATGCCCTGGAGGACGAAGGCTGCCAGGAAGCAGCTTTCGGAAACATGGTTATCCAGTCGCTCGCCACCAAAACGCTCCTCGCCACAGAAACTCACCTCACCAAATCATCAACGCAGCAGTGCCAGCAGCAGCGAACACACGAGCGATCTTTCTGTTGGTCCATGTTGTGGCTTCGAAAGCGACAGCAATCCCTCCTCTACCTCTAGCACAGCATCGAAATCGATGGTCATCGATAAGAGGATGTCCCCGAAAGCAAAGCCTCCGTCACCAATGAATGATTTGATACCGCGTAGGGGTCGACGTCCACGGAATACACCACTTAACAATCCACCCAAAAGACAGAGAAGGTTTCTGGTCAGAAGAGAGTCTCAGAAGCGAAAGGTTATGGCAGAAAGGGTTACCGAAGAGAATAAAAAGTCTGATCAAACGGATATTTTCCCGCCGGAAGAAAGGGTGGAAAACAGTGTCCAATCTATTGATAGCACATCCGACGTTCAAAAGGAAGTGCCGTGGAATGCGAGCCCAACGGACTGCAATGACATCAACTCAAGTCGTTTCGACTATGAGATAATCCATTGTGAAAAGGAGACGGAAGTCATTTTAAATGACGTGATAGAGGGTTTCAGCCAGACAACAGATGCTATAAATGAGGAGTTAGTTAACGTAACTGCAGCTCCAAATTCCTTAGACGTTGAGGAAGAACTGGCCAAACTGGAAACAAGACCCATTAACGAGGCATGTACGGGTGTTCCGAGTGATGGGGATATGTCCGTCAAGGAAATACTGGAACATCTGGAAGCCTCTAGCATAATAGAAAATTCATCTGATGATCTTGCCGTTAAAAAGGACATCGAAACCATTTCGAACGCCATCCAGGCTGAAGCTGACTTAGTACAATCCGAGGAGTTGACCTCGTCCACCGAATCCAGTGAATCGCAGCCGCAATTTATTCTGCAACAAATGGAAATCATAGAACAACATGAATCCAGTGAATCTGTTGATCAGCAGGAGATGATAGTAAGCATACCGCTGGAGGTGCTAGATGAGAATTTGCAGCGTCGTCTTTGCGTGGATCCGGAAACTGAGGAGCTCCTGGAGAGCGGCAGTGCCACGTCCAAGGACTGGCCCTTGCAACCTGATGATGTCAATAACAATGAGAATGATGAAAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCGAAATCAAGAAATTGAAGCGATACAAACGAGGGAAATGGATTCCGATGAAACGGATTCGTCTGACGTGCAGCCGGTGCGATCTAGACCAACGCCCATGGACTTTATGGCCGAGTTTGCCAAGCACTGTGCGAACGGTGTTGAGCAGCTAAAGGCCACCACTCCAGCACCATCACCCACTCCCACGGATTTGCTGCCCCTTAACGATCTGGAGGCCAAGCAGAAACTAGAAGTGGAGATGAACGACGTGGAGACCACTCTCAATGGCATACTCAGCGAGATGCAGGACCAGCACATGTATACCTCAAACTGTGCCCACATTGATGAGTTCCTTACTCCCGCCGATTATGCTCCAATGACTGAACAAGAGACGTCCGTTTCATCGCCGCCCAATCCTTTCGAGCAGAGTCCTATTGCTGAGCCTGAGCCCAAACCTAGTGCCAGCGATGATCCCTTTGATAATAGCAACTTTAGTAGCGAACTGATTGGCTTCCAGAACGACATTCCTTGCTTTGAGAATATTGAGACCACAACAGAGCAGGGACAGAATTTGCATTTAGAGCTAACCCAGTTCTTAAGGGATCTTCAGCCGGCACAGCCGATTCAGGAGCAACAGGAACAACTCGTCGGGACCGAAGCTGAGACACTGGAGACCGTCCATATTGATGGCCAAGCCAACCTCCAAGTGCAGGATGTCCTTCAGCCCCAAGTTGAGTCTGCAGAACAGTCTCCAAATGAATCTCCCATATCATCGCCCCAAGTTCAGTCACAGATTGAAATCCAAATGGAACCTGAAATCGAGACTCAGATGTCTCAGCACGAGATCCTAACAGTGCAGTCTCCTCAGCATCAGCCTCAAGTACAACCTCATGACCAATCTCAGATGCAACTTCAAATCCCACCGCAAATCGAGCCTCACATTCAAATCCAAAACCAAGAGCACCAAACTCTTCAAATCGTTCCGCAAGTTCAGCACCAAGTGATACCCCAAGTGCATCATCCTCAGCTGCAACTTCAGTCGCAAGTGGTGCCCCATGTCCAGACGCAGGGCACGACGACGACGGTCACCTATGAACAGATCTATAAACAGCACATTGTCCAGCAGACAGTGCAGCAATCATCCAACAAGATGCAGGTCATCTCGCTGCCCTCGGCTGGATCCGAAACAAGGCAGTGGCAGACCCAACAGTCACAGCAACGACAGCAACAGGTCCAGTGGTCATCGGTGGGCGGACTGGAGGCCATAAGGAGTGCGCCGACGGAAAGAGTTGCACCCACAACTACCACATACTACATCAATGCCAGCGATCTGTATCCCCAGCAGAACGAAACTTTCACTATGCTACAGCCAGCCGGCAATGACAGCTACATGATAGAACAGGTGaaccatcagcagcagcagcagcagcagcagcaacaacatcgccagcagcaacagcaaattCAGCTagcccagcagcaacatcttcAGGCGCAACAACAACCGATTATGATACTTATCCAGCAGCCGGAGTCTCAGAAACCGGTGGCCTCGTCTAGCAATCCTCAGCAGGCACCGATGCATATCTTCGGTGCTAACATCGGCAACAATGCCCAACAACTTCAGCACACGCAAAGCCAACAGATACGACAGCAATTCCAACGACAGCAGTATCAAGCTTTGCCGCAACGAAATCGCCTGGTACAAAGCCATCCAGTATTGGGAATGCCGGGAGCAACATCCATATCCACCAAAGTTACCCCCATTCCCGTCCCCACACCCAAGGGTCGGGCGCTGACGCTCAAGTGCCGCTTCTGCCACAATGGACCGCGATTCTCCAGCAGCCTGGAGTACAGCCGACACATCATCGATCTGCATCCGGCGGTGGCACCATTCAACTGTCCACACTGTCCCGTGGCCTTTGCCAGCAGGACAAAGCGATCACAGCACATCCTTAGCCACCATGTGGTGCAGCAGTATCAATGCGGTCAATGCCCCCAAGTGTTCCCTTCCCAGAAGGCTTTGGACGCGCACATTCAGCGGATTCATATGCAATTGCAGAAAGACCCTACTCCAGTGAAATTGGACGATGTCCAGCTCGAGATCACCAACCAACGAAAGCGGGGTAGGCCGTATAAACCACggttgcaacagcaacaacatcaactacaaccacaacagcagcagcagaaacaagTGCAGCAACTGCATCaaccgcaacagcagcagaaacaagTGCAGCATcaaccacagcaacaacagcagcagcagcaacaacagcagcagcagcaacaacagcagcagcagcaacaacaacagcagcagcaacaagtgcaacagcaacagcaacagcagcagcaacacgtGTTGGCAGTGCAGCAAGCACAGCAACAACCGTTAATGCAGCCACAGTCGCCCCATCCATCAACCATGGAAATCCAAGCAAGCCCAACCACACCACGGAAGATTCTCTGTTGTCCAGATTGCGAAGATTGTACTTCCGGCCATCATGGCAGCGAGCACTTTGAGGAGTTGCCGTCGGTGCAGGCTCCACCAACGGTGTTGACTCCGCCTTCTACAATTGTCTCTGCACCTTCGCCTCAGCCTATGATGTTTTCGCAGCACATAACAATGCCCTCGCCGGAACAATCCGAGCCAGATTCCACGACCACGTTGCGACAGTATCGTAAGCGTGGTGTTATTGTAGGGCCACAGGGCCCATTGCATGTGGCCACGCCAGTAGCATCACCATCACCGTCATCGTCGCCCTCCTCGTCGACTGTGGATCATGCGCCGCCAGCTTCCCCAGCTCCGCCTGCTTCTCCAGCTCCGCCTCCATCGCCCGCTCCACCGTCCATGGTGCAGTTAAACGACCTGCGGACGACCCATCAGTGCCTGTACTGCGAGGATCGATTCACCAATGAAATAGCACTGAAGAAGCACCATCAGCTGGCCCATGGATCTCAGGCGACGATGCCGTTTGTGTGCACCATTTGCAAGCGTGGCTATCGCATGCGAACGGCGCTACATCGGCACATGGAGTCGCATGATGCTGAGGGACGACCCTATGAGTGCAACATATGTCGCGTACGATTCCCGCGACCATCGCAGCTGACGCTGCACAAGATCACGGTGCACCTGCTCTCGAAGCCGCACACCTGCGACGAGTGTGGCAAACAGTTTGGTACAGAGAGTGCCCTAAAGACGCACATTAAGTTCCATGGTGAGCTTGGTTACCAGTGCGACGGTTGCGATCGGACATTCGAGTATCTCAAAGAATTGCGCAAGCATCGTCGCACCCACAGCGAGATGTTTTACAAATGCAAGTTTTGTCCAAGCTCCTTTATGCGTTTCACAAGTTTTCGGGCGCACATGAACACCCATTTGCCCATGGGCGTATTTCTCAACGAGGAAGCCGCATCAAAGTCACCCAGCAACAACACTAGCAACACGAACAGCAGCGATAAGCTGGAGAATCCACCCACACCCATCGAAGAGACACCATTGACACCGATGAGCAGTGGCGGACACGTGTACAACAGTCTAGACGAATACCCCAATTCGGTGGAGAGTTGTGCTGGCAACAGCCTGGCCCAGGAAACTATTGCCGCAACGCCATAA
Protein Sequence: MSATRRRRSSFFCANSTLSATTETTTTTTTMKATEVKEKEVSATAEVAITHAPAKEKLSLPSADEDLLNMPRICRCCCKRDLELLGLFEASQPTLANTSASNKSSGTLAKTCATEAETETRETLSANPVNPGTKATSSPSEAVTPTATTPTTGTETATATTSSAFSTTPSASTFTSTSTSTSSTSPVRRRTTFATTMATAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKDQKKSQHYRQEVSTNREQSVRKRRMVSESEEEFTGEAAVAVKQVRTESKDLPPPKSSPVQQRLRKLRTFSIGCVMDASSMPWRTKAARKQLSETWLSSRSPPKRSSPQKLTSPNHQRSSASSSEHTSDLSVGPCCGFESDSNPSSTSSTASKSMVIDKRMSPKAKPPSPMNDLIPRRGRRPRNTPLNNPPKRQRRFLVRRESQKRKVMAERVTEENKKSDQTDIFPPEERVENSVQSIDSTSDVQKEVPWNASPTDCNDINSSRFDYEIIHCEKETEVILNDVIEGFSQTTDAINEELVNVTAAPNSLDVEEELAKLETRPINEACTGVPSDGDMSVKEILEHLEASSIIENSSDDLAVKKDIETISNAIQAEADLVQSEELTSSTESSESQPQFILQQMEIIEQHESSESVDQQEMIVSIPLEVLDENLQRRLCVDPETEELLESGSATSKDWPLQPDDVNNNENDENFCQSATADSFNSAVALRNQEIEAIQTREMDSDETDSSDVQPVRSRPTPMDFMAEFAKHCANGVEQLKATTPAPSPTPTDLLPLNDLEAKQKLEVEMNDVETTLNGILSEMQDQHMYTSNCAHIDEFLTPADYAPMTEQETSVSSPPNPFEQSPIAEPEPKPSASDDPFDNSNFSSELIGFQNDIPCFENIETTTEQGQNLHLELTQFLRDLQPAQPIQEQQEQLVGTEAETLETVHIDGQANLQVQDVLQPQVESAEQSPNESPISSPQVQSQIEIQMEPEIETQMSQHEILTVQSPQHQPQVQPHDQSQMQLQIPPQIEPHIQIQNQEHQTLQIVPQVQHQVIPQVHHPQLQLQSQVVPHVQTQGTTTTVTYEQIYKQHIVQQTVQQSSNKMQVISLPSAGSETRQWQTQQSQQRQQQVQWSSVGGLEAIRSAPTERVAPTTTTYYINASDLYPQQNETFTMLQPAGNDSYMIEQVNHQQQQQQQQQQHRQQQQQIQLAQQQHLQAQQQPIMILIQQPESQKPVASSSNPQQAPMHIFGANIGNNAQQLQHTQSQQIRQQFQRQQYQALPQRNRLVQSHPVLGMPGATSISTKVTPIPVPTPKGRALTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPVAFASRTKRSQHILSHHVVQQYQCGQCPQVFPSQKALDAHIQRIHMQLQKDPTPVKLDDVQLEITNQRKRGRPYKPRLQQQQHQLQPQQQQQKQVQQLHQPQQQQKQVQHQPQQQQQQQQQQQQQQQQQQQQQQQQQQQVQQQQQQQQQHVLAVQQAQQQPLMQPQSPHPSTMEIQASPTTPRKILCCPDCEDCTSGHHGSEHFEELPSVQAPPTVLTPPSTIVSAPSPQPMMFSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHVATPVASPSPSSSPSSSTVDHAPPASPAPPASPAPPPSPAPPSMVQLNDLRTTHQCLYCEDRFTNEIALKKHHQLAHGSQATMPFVCTICKRGYRMRTALHRHMESHDAEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDGCDRTFEYLKELRKHRRTHSEMFYKCKFCPSSFMRFTSFRAHMNTHLPMGVFLNEEAASKSPSNNTSNTNSSDKLENPPTPIEETPLTPMSSGGHVYNSLDEYPNSVESCAGNSLAQETIAATP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -