Deug008103.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila eugracilis
Gene Symbol
HIVEP2
Assembly
GCA_018153835.1
Location
NW:414030-436558[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00065 0.041 14.0 0.4 1 23 426 448 426 448 0.98
2 8 0.00027 0.017 15.2 2.9 1 21 454 474 454 478 0.89
3 8 0.032 2.1 8.7 0.1 1 19 1058 1076 1058 1079 0.93
4 8 2.4e-06 0.00015 21.7 2.0 1 23 1771 1793 1771 1793 0.99
5 8 1e-05 0.00064 19.7 5.3 1 23 1799 1823 1799 1823 0.92
6 8 0.00011 0.0071 16.4 2.7 2 23 2274 2295 2274 2295 0.97
7 8 0.00069 0.044 13.9 1.2 1 23 2301 2325 2301 2325 0.91
8 8 0.0022 0.14 12.3 2.7 1 23 2346 2370 2346 2370 0.92

Sequence Information

Coding Sequence
atGGAAAATGCAACAACCACAACGGCCAAGCATTACAAAACCGCAGGCAAACAGTACAAGACCAATAAAGTGAACAATACGCGACgtgccacagcagcagcagcagcagcggcagcagcagcaacatcaactacaacaccagcaacatcaaccAAGAAGCGGACATATCGGGAAACTGCAATAGCAACCACAGTCACTCAGAGGACAGCCAATAAGGCTAACATTGCTGCAGCGGTAGCATTAGCAGCTGCAACAGAAGCGGTATCAGCAACCGAAACTACAACAGTGGCAACATTAACAGCCtccaaagcagcagcagcaacagatgTTActagcagcaacatcaacagcaacaacaacagcaaacccAGTACAAGTACAAGAGATAAACTAAGTGAGTTGCCGCTGCCGACTGCTGACAACACCAACCAcatcatcaacaacaacaataacaacaatacaaataataataataacaacaaccacCACAGTGATAATAGTATTAGTGAGAATAATTATGAATTTAAGTGTAGAGATAAAGCAAGTCTAAGTGATAGCAAAATGACGCTACAACAGATGGCAGCAGTCAGCAGCAACCAGGAGCCAGTGGCTCCGAATGTGGCCAACACGATGAGCAACGCAAGCATCCTTATCAATAGCCAACAGACCACCGTAAATGCCACACCCGCCACCGATGAGGCTCCGTTGGGGGATTGGTCAAATATTTCACGCTATCTGCACAAGAAGTTTAAACGTTTGGCTAGCACCACCGATGTGGAGACCGGTAATGGTGCGACgaatggtggtggtggtggtgcggcACATCATCCAAGTGGCGATGGCGTTCGCACCACATCGTTGTCCTCAAACAGTTCGCTTTCACCGCCGCCACCAACGCCGCTGGCCAATGGTCATCACCATCTGATGacccaacagcagcaagtgcagcagcaacatcagccgTCGCCGCAGCAGCTGCCACCCCAGGCAGCCACACATGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATTGGTCATGAGGAGAGCATCATCAGCAATAGTGGATACAAGGCGGCGGCAAGAACGCGAACACCACTCAGTAATAGCAACACGAACAGTAATAGCAACTATGCTGCGAATGCCACACTCTCACCGGCAACATTTGCCCAACATCAGCAAATGACACAGCCAACAACGGTTAGTCCGGGAATCCCAGGTGGAGCAGCAGCACTGGCAAATCCTGTAGGAGAAAAGCCCGGACGTTACGTTTGCACTTACTGCAATCTGATATGTGCCAAACCCTCGGTGCTAGAGAAGCATATTCGAGCCCATACCAACGAGCGACCGTATCCGTGCGACACCTGCGGCATTGCTTTTAAGACGAAGAGCAATTTGTACAAACATTGCCGCTCGAGATCGCATGCAGCCAGAGCTCGGGGCCTGGAAGTGCCAGCCGATGCAGATGATGGATTGTCCGATCAGGATGCAGAGCTAAGCAACAGTAGTTCGGAATTGCCAAGTCGCGCTGGATCGCCTTACGATGAGCCAATGAATTCGCCCACACCCTCACCTTCCACATTGTCTGCGGCCAAGAGTGCATACATTCAGCAGCCACCGCTCCCACAGCATATGCAACAATTGCCGCTGGGCTCGCCGGCTGCTGGGACATTGCCACCTACAACAGCGGAAAATCTCCACTCGGCCACTGCCCAGCATCGTTCGTCGATCGACTACAAGCCATATAAACCCAAGTTTCACAACGCCGCCCTGTATGTACCCGGCAGCAGCaaggaacaacaacagcagcagcaacaacagttgcagattcagcagcaacatcagttggcccagcaaaaGCTATCCATTCAGCTGCCTTTGGTGCAGCAGCCATCGCTGGCACATCCAACTCTGTCGCCCAGCACGCAGATGAAGATGAAGCATCATATTAACTCGCATCAGctccagttgcagttgcagcaacagcaacagcaatccCTGTTGGCCCAGCAATCTATGTTGGCCGCCATGCCACCTGGTGGGGTTTATTACCTGGGTCAGCCTCCCTACTACAATCAAGATGCAGCGGCGGCGGCCATTCACCAGCATGCGTTGGTCCTTCAGCAATTTCAACTGCAACAAATTCATTTGgctcagcagcagcatcagcaacagcaacagcagcagcagcagcaacaacaacaactttcGCCTTTGGTAAAGGCGCCACCACCAATGCAACAGCCTCCAAGTCTGCCGCCTCAACAGCTGGTGCGAGCCAATAGCCAAGTTTCCAATGTAGCAACAGCACCTGCCACTCCCACGCCCGCCGCTAATCTCAGCAGTTTTGCCAGCTCCAGTGGTGGCAAGCAAGTTAATGTGGCGAAAGTACAGGAGCACATTTCCAAGTTGATCTCTCAAAATGAAGCGATTGTGGAGAACAAGGAGATATTGTTGCAGAAAAAGTACCCCAAGCAGCTGAGTCGTTCTCGTAGCTTCAACAatgccaacagcaacaatacaTCGCAACACGGTAGCAACCCGTCGACATTGCCTGCAAGCAACAGTCACAACTTGAATGCCCAGATGCCGGAGCGGGAGACTAAAGTGAATTTGGCACAAGCTATCGttcaaaagcagcagcagcagcaacttcagcaacagcaactgcagcagcaacaacagcagttaATCCAACTTGAGCAGCAGCCCTACTATACGTacatgcaacagcagcaggaaaacCAACAGCTGGAACCTCCTAATGGCTTGGTTAAAAGGAATAACAATTATAAGGTTGCGCCAGCGGTGCCTGTaaagcagcagccacaactgCCACCCCCGCCTTCTCCATTGCCCATGCAAACGATGCAGTATCGCCAAGATCCTGCAACGCCAGTGGCTAAAATTGAGCAACCAGCAACGGCAGGGCATGTGATGCCTTTAAACTTATCAGCGAAGCCTAAACCAACGCTGGTAACTGTGCCTGTTAGTTCCTTGCCCACCAGTTCTGCACCAACGACACCTGCAACATCAGGGAATCCGGCTGGTAGCTCCAAAACTGGACCACCACCCGCCCAGGTGAATAACTCCATCATCAAGAATCTGCTGCTAAATGCTCGAGGATTGGCAGTGCCAATTGGCGAGGGTGATGATGCTGTCTACTCGTGTCCGATCTGTGCGAGCGAATTCCGCAGTGCGGATGACCTGAAGCTGCACAACAGTACTTACTGCCAGGATGCCAGCTCCAGTGCGCCAATGAGTCCGGCATCTTCTCCCTTCCGCTCCAATTCGATCTCGTTAAGTCTGCCGGAGCTGAAAAGTCACATGGCGAACTCAAAGAATCCATTATCTCTGGCCAAGTTGGCCTGGTCGCAGCTGAAAACCAAGAGGAGTAGTCTGGTATTAAGTCGTCTCAGTGCGGCACAAACCCCAGCGAGGACATCTACGGTAACAGCTCCCACTGTAACTGCATCGGCATCAGCTCCTGTGTCAGCGTCGCCCACAGTTCTTATACAAATAtcagctgctgctcctcaGATTGAAGCTTTGCGATTTGTAGATGCACCACTGCCATCGCCGGGTCCGTTGTTGGGTAAAACGCCCCTAGTGGACTATGCTCAGCAAAATGCTCCCCGAAAGACCCAAGACTCTGTGGTTATAACTAAAATGCACGAGGATCGGCAATTTGCTTTGCGAGATTTGGAGGCTCAGCCCGCCAAGCGTGTCAAAACCAACGACATGGTGGTGGCATCCTCTACTCAGCCAACGacaaactttaactttttcaaCAACCAGAATAACAGCAATAATGTACCGGAGATGCAGTTCTCCAAAGAGGAGCGACTGCGCAGATTCACTTCCTCTGGCGGCAGTATGATTCCCATTTCTGAGTGCCCAGACTTGGATAACAGTCCTAAGATGATTCGTACTCCGTTGCTGTCCGGTGGAAGCTTCCAGGACGTTTCAGTAAAAGTCAACAATGAGATGGGATCGTCTAGTAAGGAGCGCAAGCTGATGGCACTGGCCACTGGTAGTGGACTGCTTGGCGTTAGCTCTGGCCCGCAGCACTTTCAGTTTCCGCCCATTAATTCTATAACTGCCTTCAATCCCTTAACGCTGCCACCGATGAGCGGTGGGGATAAAACCACACCAGTTACACCAATACCTCATGTGCCTGGAATGCCAGGACCGGGTAGTTTGACGCCACAAATGCCTCTACTGCCACCTCCACCACAACAACTCCAGTTGCCAATTCCTTCAGGACGAGGACGTAGTCCGAATCGCAAGCAACCGAGTCCACTTCTTTTGGGAGCAGGAGTAGGTGAACTAAAGGCTTTGTCGCCATTCGGTGGAGTTCAGAATGTGCCAAGCGAATTCAGCCGACAACCACCAACTCCAGCTCAACGGCAAGCTCTGCAATGGAACAGCAAGGAGACGTCAAAGAAAGCACCATTTAACTTTCTTCGCATGGCTGATAATGTGAAGACTGCGGAACCTGAAGGGCGTCACTTCAATTTGGAAAATGTGATTGCTGGAAAACAGGCAGAATCGTCGCTAACACCACTGCACGTGGAGACTCCCGCTGGAAGCACCACAGAGGAAGCCAATCCTGTTGCCAGTTCTTCGACATCTGCTAAATCGAAGTTTTTGCGACCCACTAGTCTGCCACTTAAACCTGGAACCTTTACTCCAAAACGCCATCATGGCATTACACCTACAGCGAATACATTGCCGCTGATCTCGCCGGAGACTCCCAGGCCGTCCAAATCCTGTGTGCAACTGTATCTCAATGGACATGCCTATACCTATCTGGGTCTCAAATGCAGCACAAAGATGTTTTACTGTACGGTGAACTGTCCGCAACCTTCGTATGTTGCCGGTATGCATAAACTATCTATGTATAGCGTGTGGCAAGTGTGCGAGGAAAACCAGCCTCATCCACTTGGATTCAAACTAAAGCAAGTAATGGCTCTCTATGACTCACGTCAACGGATGCTGGGAAATGGCAGCTCCACTGCAATGGCTGGAACAGGAAAACTAAACTATAATCTAGTGGCCTCTCAGCAAACTGTGTCATCCACTTCGACGTCGTCCAGCAGCAGTGCCTTCTATCAAGGACCATTGAAGACCCCACCAACAGTTACGGTGGCTGCTCTCAGCGAGGCGAATGTTGCAGCCAAGGCCAATGAGGAGGCGCAGGCCAAAAAGCTGGAGACAAGTCCGTCTGGACAGCCCCTGGTGGGTGGCTATGAGTCTCACGAAGATTACACGTACATCCGTGGCCGAGGAAGGGGAAGATATGTTTGCTCTGAGTGCGGCATTCGGTGCAAGAAGCCATCGATGCTTAAGAAGCATATTCGCACCCACACGGATGTGCGACCATTCACATGCAGCCACTGCAATTTCAGTTTCAAGACCAAGGGCAACCTGACCAAGCACATGCAATCCAAAACTCACTTCAAGAAGTGCATTGAACTGGGCATCAATCCGGGACCAATGCCACCAGACAGCGAGTTCCTGGATGTGGATATGGACTTCGACCAGCAATCGTCCACTTCGGCAGGAGGCCGCACATCATCCATGGCTGGAGAGTCCGATTCAGATGATTACAGTGACAATGAATCGGAAAGTAGCGATACGGATGAATCCAAGTCCCGATTGAAAGAGCACGAAGCTGCTAGGGGACTTCTTTCGCTATCGATGACGCCGCCAATTCCGCAGAGCGTGTCGCCTTACCCACAGATGCAGGATACACCACTACCGGCAGCCAGTCCTGCAAACAGCATTGGTTCCTCCGGATCACAACCCAAGAGATTGGTGTGCTCTTTTACGTCGCCCAAGCCACCGTTCGACTACCAGAAGCAGGAACAGTATTATTCCAATCCAGAGGAGTCCAAGCCAAAACGAAGCGTGGCCAGCGAGGAGAGTGCACCCATGGATCTTACTAAGCCGCGCGGCTCCATGACAGCCATATCCCCTTCACCAATTCCACCGCATATACAGGATCTTCCCAAATCGCAAGCCCAGCAGATGCACGATGTTATTTTCGGCAGCTCTGGCAACGAAAGTGGTTTCATGAAGACTCTAATCTCAGTGTCAGACAAGGTTCGCATATCCGCTGAAATGGAGGAGCAGGCCAAGCACGAGGCAGAGGGTGAGGATGTTCATCTGCAGACCTACATCAAGGAACATGCGCTGCACCAAGCCAAGATAAAGCAGAGTCAGTTTAGCCGTAGCTATCTGATTAATACTTTGTACACTGCGGCGTCCCCCGTGATCAGCAGTAGTTCATTGTTTACCACAAACAGCCGGCCCGTTATGACCATTAATGAAGTTCCTAGCATCGAAGTCCACGAGGTTAAGACTCCGGAAGCCGTTGAGTTGCCAACCATTGCTCCTGCTGTCACTCCAGTTACTCCAGCGGCAATTCCCGCTAAGATAACCGAGGAAGAGAGCGAGGAGAACAAAGCGCAGTCGGATCAGGAGAAGCCAAAAGTTGTCGAGCCACATAATGCTAATCTGCCCGCTGCAGTGCAGCAACCGGATGCCAATGATTTCAAGGGAGTACTTGGAAATCCGCCCCCACCAAAACCAACAGTGTCTGTGGCTGTGACAGCAACTACATCAACATCTATTCCTGTGGTACCCTCATCTAACGCCAACTCAAGTCAACCCACACAGCGTACTGTGATTGTGGGTGAAGATGGCTTTAAAAACTCAACGCCCAGCAGCAAGAGCAGTGATCTCCAGCATGTGTCCTACGGCAGAGGAGTGCCACCAGCTCCCATTGCTGGAGATGCACGTCCCACGTGTACCATCTGCGCCAAAACTTTCCAGCGGCAACATCAGCTAACTCTGCACATGAACATTCACTACATGGAACGCAAATTTAAATGTGAACCCTGCAGTATATCCTTCCGCACGCAGGGACATCTGCAGAAACACGAGCGATCGGAGGCGCACAAGAACAAGGTGATGATGACGTCCACGTTTGGTGTTCCAACTACCTCGAATCCACGACCTTTTGAGTGCACGGACTGCAAGATCGCCTTCCGCATCCATGGCCATTTGGCTAAACATCTGCGTTCGAAGACACATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTTGGAACTTTCGCCGAAATTGAACGTGCTGGGATAAGTCTTACAGAAATCGATACAAGCGACTGTGAAAATTCGCTTATATCGCTGAAGTTGCTGGCCCAGAAACTGCTGGAGAAGGATCCAAGCAAATTGAGTAGCTATACCACACCCTCTGGCATGATGCAACTGGCCCAGGATGGAACTGGTCCTGTATCGCAGGATAGTGCATCTGAAGACGGCTTTAGTGTTGCTATTGCCAATGCTATAGCTTCGCTGGACAATGACAGTGCTGGGAACACACCCAAGCGTGCGAGCTCCATGTCCGAGGATGAAACGGTTACCAACGGCTTGAATCATAACCTGAAGCGTCGTTTGCCAGGAAGTTTTAGCAGCACTGGCGAGGAGAGCGATAATCCGGCAGAAAACAATGGTGAGAAGCGAGCTCGATCTAGCCAGGAGCTGCCTGTACCCGTGCCCGTGCCCGTGGCTGCTTCAGGAGCGGCCAGTAACTGA
Protein Sequence
MENATTTTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAATSTTTPATSTKKRTYRETAIATTVTQRTANKANIAAAVALAAATEAVSATETTTVATLTASKAAAATDVTSSNINSNNNSKPSTSTRDKLSELPLPTADNTNHIINNNNNNNTNNNNNNNHHSDNSISENNYEFKCRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNASILINSQQTTVNATPATDEAPLGDWSNISRYLHKKFKRLASTTDVETGNGATNGGGGGAAHHPSGDGVRTTSLSSNSSLSPPPPTPLANGHHHLMTQQQQVQQQHQPSPQQLPPQAATHEFSANFVNSNHVNAIGHEESIISNSGYKAAARTRTPLSNSNTNSNSNYAANATLSPATFAQHQQMTQPTTVSPGIPGGAAALANPVGEKPGRYVCTYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPMNSPTPSPSTLSAAKSAYIQQPPLPQHMQQLPLGSPAAGTLPPTTAENLHSATAQHRSSIDYKPYKPKFHNAALYVPGSSKEQQQQQQQQLQIQQQHQLAQQKLSIQLPLVQQPSLAHPTLSPSTQMKMKHHINSHQLQLQLQQQQQQSLLAQQSMLAAMPPGGVYYLGQPPYYNQDAAAAAIHQHALVLQQFQLQQIHLAQQQHQQQQQQQQQQQQQLSPLVKAPPPMQQPPSLPPQQLVRANSQVSNVATAPATPTPAANLSSFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNTSQHGSNPSTLPASNSHNLNAQMPERETKVNLAQAIVQKQQQQQLQQQQLQQQQQQLIQLEQQPYYTYMQQQQENQQLEPPNGLVKRNNNYKVAPAVPVKQQPQLPPPPSPLPMQTMQYRQDPATPVAKIEQPATAGHVMPLNLSAKPKPTLVTVPVSSLPTSSAPTTPATSGNPAGSSKTGPPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASASAPVSASPTVLIQISAAAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQNAPRKTQDSVVITKMHEDRQFALRDLEAQPAKRVKTNDMVVASSTQPTTNFNFFNNQNNSNNVPEMQFSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNEMGSSSKERKLMALATGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSGRGRSPNRKQPSPLLLGAGVGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKETSKKAPFNFLRMADNVKTAEPEGRHFNLENVIAGKQAESSLTPLHVETPAGSTTEEANPVASSSTSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGTGKLNYNLVASQQTVSSTSTSSSSSAFYQGPLKTPPTVTVAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPQMQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRGSMTAISPSPIPPHIQDLPKSQAQQMHDVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVHLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVISSSSLFTTNSRPVMTINEVPSIEVHEVKTPEAVELPTIAPAVTPVTPAAIPAKITEEESEENKAQSDQEKPKVVEPHNANLPAAVQQPDANDFKGVLGNPPPPKPTVSVAVTATTSTSIPVVPSSNANSSQPTQRTVIVGEDGFKNSTPSSKSSDLQHVSYGRGVPPAPIAGDARPTCTICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTFAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPSKLSSYTTPSGMMQLAQDGTGPVSQDSASEDGFSVAIANAIASLDNDSAGNTPKRASSMSEDETVTNGLNHNLKRRLPGSFSSTGEESDNPAENNGEKRARSSQELPVPVPVPVAASGAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00592606;
90% Identity
-
80% Identity
-