Basic Information

Insect: Drosophila eugracilis
Gene Symbol: Ctcfl
Assembly: GCA_018153835.1
Location: NW:7935735-7938895[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.39 25 5.3 4.7 1 23 290 312 290 312 0.95

2 11 1.2e-06 7.8e-05 22.6 0.7 1 23 318 340 318 340 0.99

3 11 0.00059 0.038 14.1 2.8 1 23 346 369 346 369 0.97

4 11 0.32 20 5.6 3.8 1 20 375 394 375 397 0.95

5 11 0.0023 0.14 12.3 1.8 1 23 403 425 403 425 0.98

6 11 3.6e-05 0.0023 18.0 1.2 1 23 431 453 431 453 0.98

7 11 0.00045 0.029 14.5 2.9 1 23 461 484 461 484 0.97

8 11 0.034 2.2 8.6 0.6 2 23 491 512 490 512 0.96

9 11 0.0049 0.31 11.3 3.9 1 23 518 540 518 540 0.98

10 11 1.3e-06 8e-05 22.5 2.8 1 23 546 569 546 569 0.96

11 11 3.6e-06 0.00023 21.1 3.0 1 23 583 605 583 605 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.39	25	5.3	4.7	1	23	290	312	290	312	0.95
2	11	1.2e-06	7.8e-05	22.6	0.7	1	23	318	340	318	340	0.99
3	11	0.00059	0.038	14.1	2.8	1	23	346	369	346	369	0.97
4	11	0.32	20	5.6	3.8	1	20	375	394	375	397	0.95
5	11	0.0023	0.14	12.3	1.8	1	23	403	425	403	425	0.98
6	11	3.6e-05	0.0023	18.0	1.2	1	23	431	453	431	453	0.98
7	11	0.00045	0.029	14.5	2.9	1	23	461	484	461	484	0.97
8	11	0.034	2.2	8.6	0.6	2	23	491	512	490	512	0.96
9	11	0.0049	0.31	11.3	3.9	1	23	518	540	518	540	0.98
10	11	1.3e-06	8e-05	22.5	2.8	1	23	546	569	546	569	0.96
11	11	3.6e-06	0.00023	21.1	3.0	1	23	583	605	583	605	0.98

Sequence Information

Coding Sequence: ATGTCGAAAAGGACAAAAAAGGATGAACATTCCGAGGATCTGCAGTCTTTCCTCAATAATTTCCACAAGGAAATCGAGGACAAAAGCGATGACAAGGTGGTCCACACAATTTTGAAGGCCATTCGGGCAGAGGACGGTGACTTGGAAGAGAATGACGATGAGGAAGCTGCAGCTGAAGAGGAGCAGCACGCAGAAAATGACGCAGAGGAGGcggaagaagaggaggaggacgacgaCAAGTACTTCATAGATGACGAGGGAAACTGCTATATCAAGACGACGCCCAAGAAACAAAAGGAGTTGCAGAAGAAACTTAAACAGGCAGCTGTCAAGCCCGGAAAAGTCACACGATCGGTGGTCGGCAAGGCCTCCAATAAATCAATCAATCTGCGTCCAGCCAAATCACCACCAAAAGCAGCCACATCAAAGCCACCGCCAGAAACCAAGTCAATAAGCGTACGCCCTGCTCGAGCAGCTGCAGCCAAACAAAAGTCGCCTGTGATGCCGCCTCCACCGGCACCAGTTAACAAACTACCAAACACTAGAGGCAGGCCTAGGAAAAACCCCATTTTACCGAAACCCGAACCCTTGGACCTGGAGCGAGAGATCGAAGAGCTTGTGGATGATCCTGATATCAGTTCAGTGGTCAACGAAATGGTTGACTGTGAAATCGACAGTGTTGCCGTAGAAGCAGCAGTTCTAGGATCGAACGATAATGAGGTGTATGAGTTCGATGACAACGCAGAAGAAAAGACGGCAGATGAGGAGGTAGTTGACAAGAAGGATCTTGACTTTGTGCTAAGCAGCAAAGAGGTAAAGCTGAAGCCAGCTTCTGCCAGCCAGAATGCAAATGCCTCGGCACAAAAGTACTTATGCCCCCACTGCCCGTACACGGCATCCAAGAAGTTTTTGATCACGCGTCACTGCCGTACTCATGACACCGAACCCGCCTTCAAGTGCTCCATCTGCGAGAGATCGTTTCGATCTAACGTTGGACTTCAGAATCATGTGAATACGCACATGGGTAAAAAGCCGCACAAATGCAAGTCCTGCGAAAGCGCCTTCACCACCAGCGGCGAACTTATCCGGCACACCCGATACAAGCATACAAAGGAAAAACCGCACAAGTGCACGGAGTGCAGCTACGCCAGCGTTGAGTTGACCAAGCTTCGTCGCCACATGACTTGCCATACGGGCGAGAGACCGTATCAGTGTCCGCATTGTACATACGCCTCGCAGGATATGTTCAAACTGAAGCGGCATATGGTTATCCACACAGGCGAAAAGAAATACCAATGCGACATCTGTAAGTCGCGATTCACACAGTCGAATTCCCTAAAAGCCCACAAGCTCATCCACAGCGTCGTTGACAAGCCCGTCTTTCAATGCACCCTCTGTCCGACAACTTGCGGTCGAAAAGCTGATCTGCGCATCCATATTAAACATATGCACACCGCCGATATACCGATATCATGTCGCCGTTGTGGTCAGCAGCTTCCCGATCGCTACCAGTATAAGCTGCACGTAAAGTCCCATGAGGGCGAGAAGTGCTACCGCTGCAAGCTCTGCAGCTACGCATCGGTGACCCATCGTCACCTGTCGTCGCATATGCTTATCCATTTAGACGAGAAGCCGTTCCGGTGCGATCACTGTCCGCAGAGTTTCCGACAGCGCCAGCTGCTGCGCCGCCATATGAATCTCATACATAACGAGCAGTATATGCCACCGGAACCTCGCGCCAAATTGCACAAGTGCCCATCCTGTTCGCGGGAGTTTACTCACAAGGGTAATCTTATCCGACACATGGAAATACATGACGATTCGGTGAACGCTCGCGAAAAGCAGCTCCGTCTTAAAATGGGTAGAAATGTGCGCCTCCAAAAGGATGGCTCCATCGTTACGGTGGCTAGGAATCAATACATAGATATAGACGAGGGTGAAAACAGAGAAGAGGACAATCCGGAGATCTATGACCTGGCGGAAATAGAGCCAGAAAACTCGGAGAATGAAGATACAGGAGTAGAGGAAATTTTGCCCACTACTTCGATCcggcaaaaaaataaaccagcTCCCGTTATTATCAACAAGCAGGCTAGGCGATCGGGCACCGAGAATCAGCCTACGATTATCAATCGACGCTTACGATCTCGCAGCGGCACCAAAACGTTCCATATCAAAGAGGAACCGGACAACATGGATTTTACAGTGGAACTTCAAGGTGATGATGGCGAGGTAATGGTGGTGGAGCTAGTTAACGGCGACGAGGAAGTAGTAGTAAAGCGCGAGCCAAGTGCGACATCTAAGATTAATGCCAGCaactgttttggttttgagGAGgatgatgattatgatgaGTTCGTCGGAGATGCAGAAAACGAAGTTGATGGCGCCTCACAGGAGTTTCTGCAGCTAATGGATATGATTGAGCAGGATTCTTAG
Protein Sequence: MSKRTKKDEHSEDLQSFLNNFHKEIEDKSDDKVVHTILKAIRAEDGDLEENDDEEAAAEEEQHAENDAEEAEEEEEDDDKYFIDDEGNCYIKTTPKKQKELQKKLKQAAVKPGKVTRSVVGKASNKSINLRPAKSPPKAATSKPPPETKSISVRPARAAAAKQKSPVMPPPPAPVNKLPNTRGRPRKNPILPKPEPLDLEREIEELVDDPDISSVVNEMVDCEIDSVAVEAAVLGSNDNEVYEFDDNAEEKTADEEVVDKKDLDFVLSSKEVKLKPASASQNANASAQKYLCPHCPYTASKKFLITRHCRTHDTEPAFKCSICERSFRSNVGLQNHVNTHMGKKPHKCKSCESAFTTSGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCTLCPTTCGRKADLRIHIKHMHTADIPISCRRCGQQLPDRYQYKLHVKSHEGEKCYRCKLCSYASVTHRHLSSHMLIHLDEKPFRCDHCPQSFRQRQLLRRHMNLIHNEQYMPPEPRAKLHKCPSCSREFTHKGNLIRHMEIHDDSVNAREKQLRLKMGRNVRLQKDGSIVTVARNQYIDIDEGENREEDNPEIYDLAEIEPENSENEDTGVEEILPTTSIRQKNKPAPVIINKQARRSGTENQPTIINRRLRSRSGTKTFHIKEEPDNMDFTVELQGDDGEVMVVELVNGDEEVVVKREPSATSKINASNCFGFEEDDDYDEFVGDAENEVDGASQEFLQLMDMIEQDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507775;
90% Identity: -
80% Identity: -