Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:1052974-1054637[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.7 1.1e+02 3.2 0.1 2 12 11 21 10 25 0.88

2 11 1.9 1.2e+02 3.1 0.2 13 23 210 220 202 220 0.79

3 11 5.4e-07 3.4e-05 23.7 2.0 1 23 225 247 225 247 0.99

4 11 4.1e-06 0.00026 20.9 2.3 2 23 253 274 252 274 0.97

5 11 8.5e-07 5.4e-05 23.1 0.4 1 23 276 298 276 298 0.99

6 11 0.00026 0.017 15.2 3.6 2 23 338 359 337 359 0.97

7 11 2.9e-05 0.0018 18.3 1.8 1 23 364 386 364 386 0.98

8 11 5.5e-05 0.0035 17.4 2.1 1 23 391 413 391 413 0.98

9 11 4.5e-05 0.0028 17.7 1.8 2 23 416 437 415 438 0.94

10 11 2.1e-07 1.3e-05 25.0 2.1 1 23 442 464 442 464 0.98

11 11 2.5e-06 0.00016 21.6 1.3 2 23 470 491 469 491 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.7	1.1e+02	3.2	0.1	2	12	11	21	10	25	0.88
2	11	1.9	1.2e+02	3.1	0.2	13	23	210	220	202	220	0.79
3	11	5.4e-07	3.4e-05	23.7	2.0	1	23	225	247	225	247	0.99
4	11	4.1e-06	0.00026	20.9	2.3	2	23	253	274	252	274	0.97
5	11	8.5e-07	5.4e-05	23.1	0.4	1	23	276	298	276	298	0.99
6	11	0.00026	0.017	15.2	3.6	2	23	338	359	337	359	0.97
7	11	2.9e-05	0.0018	18.3	1.8	1	23	364	386	364	386	0.98
8	11	5.5e-05	0.0035	17.4	2.1	1	23	391	413	391	413	0.98
9	11	4.5e-05	0.0028	17.7	1.8	2	23	416	437	415	438	0.94
10	11	2.1e-07	1.3e-05	25.0	2.1	1	23	442	464	442	464	0.98
11	11	2.5e-06	0.00016	21.6	1.3	2	23	470	491	469	491	0.97

Sequence Information

Coding Sequence: AtggtaaacaaaacaacatggaCTCAAACCACTTGTCGAATATGCTGGTTCAGTTTTAGCACCATGATAAACATATTCGATGGGCCATCAGAAGTTGGCTTTTCAAATGTCGACGTGATTTCACATTACACTGGGAAAGAAGTTAAACGAGGAGATGCATTTCCTGAAACCGTGTGCTCGTTGTGCATGGTGGATGCGCGGATAGCATTTAGGGCAAGACTGTCCTGCGAGGAAAGTAACCAGTGCGAAATCAAACCGAAGGAAGAGGATATAGGCGAAGTGTTCGAAATCTCGGAATTTTTTGACGAGGACATAGAAGAAGAAACGTTTAAGGGCCAAATAATTGAAGAAGGATTTGAGGAAGGTGCTTGCATTCTTCCTGACTGCGATATGGAGGAATCAAAAATTGATGAGGAAATTCcagtgaaaaatgaaaaaattggagaagaggaatatagtttagACGGCACCCAGTCTATGCACGTCCAAATTAAGAACGAGCCGATTGAGGAAGAAGAATACCAGGTATCGTCTAACTGTGATGTGACCAACGAGCCAATCAAAACTGAAATATTAGACGATGGAGCCCTAACATCACCTATTGAGCAATGTAATGAAGAAACTAAGACAAATTTACTGGAGTCCCATATGCAGACCCATAAGAAAGGATGGTTCAAGTGCAGCATCTGTCCAAAgactttttctttaaagaactcCTTAATACGACACAGAAAAATGCACGAAGGTGGCCCCTTAAATTGCTCTGAGTGCTCCATGACCTTCAACAATCGTAGCCAGTTTTCGCAACACATGCGCACGCACTCTTTTACTTGCCTAATATGCTCCGAATCTTTCGCTGTTAATAGCGATTTAAAACAACACATGCAAACTCACAATGACTTTTTATTCAAGGAGCCAATCAAAAAGGAGTTAGACGATGGAGCCCACACAAGACTAATGGTGCAATCGGATTTAAAGAAATGCACCCGGGCTATTAACAAGACATCGCTTCAATGTAGTCACTGCCGTATGCTTTTTTCTACTCAAACTTTTTTGGAGACGCACATGCAGACCCACGAGGAGCGACCATACAAGTGCCAACTCTGTCCGAAGTCATTTGTTTTACAGAAACATTTATCAATGCATGGAAGAGTCCACGAAGGCGGGCCCTTTAAGTGCTCTGAATGCTCGATGCCTTTTGTCACTCGGCGAGAGCTTATGAGCCACATGCACCAGCACGTTCTTAGGTGCTTAATGTgctttaagatttttaagagCTCCTCTGATCTGGATGTGCACATGCGAGATCACCATGTTGAACGGTTTAATTGTTCTATTTGTTCCGAGTCGTTTTCCTTTAACAACGATTTGAAAAGACACATGAGAACTCACAATGACTCTTTGTTGAAGTGTACATTATGCCCAAAACTTTTTAAGGATAAATATGCCTTGAAAAATCACCTCCGCTCTCACAAGGACCAAATTCTTCCTAACTAA
Protein Sequence: MVNKTTWTQTTCRICWFSFSTMINIFDGPSEVGFSNVDVISHYTGKEVKRGDAFPETVCSLCMVDARIAFRARLSCEESNQCEIKPKEEDIGEVFEISEFFDEDIEEETFKGQIIEEGFEEGACILPDCDMEESKIDEEIPVKNEKIGEEEYSLDGTQSMHVQIKNEPIEEEEYQVSSNCDVTNEPIKTEILDDGALTSPIEQCNEETKTNLLESHMQTHKKGWFKCSICPKTFSLKNSLIRHRKMHEGGPLNCSECSMTFNNRSQFSQHMRTHSFTCLICSESFAVNSDLKQHMQTHNDFLFKEPIKKELDDGAHTRLMVQSDLKKCTRAINKTSLQCSHCRMLFSTQTFLETHMQTHEERPYKCQLCPKSFVLQKHLSMHGRVHEGGPFKCSECSMPFVTRRELMSHMHQHVLRCLMCFKIFKSSSDLDVHMRDHHVERFNCSICSESFSFNNDLKRHMRTHNDSLLKCTLCPKLFKDKYALKNHLRSHKDQILPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -