Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:11365874-11371132[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 9.6 6.1e+02 0.9 0.3 5 16 111 122 110 124 0.83

2 13 4.9e-05 0.0031 17.5 0.2 3 23 272 292 270 292 0.97

3 13 9e-05 0.0057 16.7 3.3 3 23 304 324 302 324 0.96

4 13 3.9e-06 0.00024 21.0 1.2 1 23 330 352 330 352 0.99

5 13 1.9e-05 0.0012 18.9 3.4 1 23 357 379 357 379 0.98

6 13 4.1e-06 0.00026 20.9 0.8 1 23 385 407 385 407 0.98

7 13 3.8e-07 2.4e-05 24.2 1.0 1 23 413 435 413 435 0.98

8 13 3.4e-08 2.2e-06 27.5 3.2 1 23 441 463 441 463 0.99

9 13 1.2e-05 0.00078 19.4 8.3 1 23 469 491 469 491 0.99

10 13 7.4e-05 0.0047 17.0 1.5 1 23 497 519 497 519 0.97

11 13 3.4e-05 0.0022 18.0 0.4 1 23 527 549 527 549 0.99

12 13 0.001 0.064 13.4 3.0 1 23 559 581 559 581 0.98

13 13 0.00014 0.0091 16.1 2.9 1 23 586 608 586 608 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	9.6	6.1e+02	0.9	0.3	5	16	111	122	110	124	0.83
2	13	4.9e-05	0.0031	17.5	0.2	3	23	272	292	270	292	0.97
3	13	9e-05	0.0057	16.7	3.3	3	23	304	324	302	324	0.96
4	13	3.9e-06	0.00024	21.0	1.2	1	23	330	352	330	352	0.99
5	13	1.9e-05	0.0012	18.9	3.4	1	23	357	379	357	379	0.98
6	13	4.1e-06	0.00026	20.9	0.8	1	23	385	407	385	407	0.98
7	13	3.8e-07	2.4e-05	24.2	1.0	1	23	413	435	413	435	0.98
8	13	3.4e-08	2.2e-06	27.5	3.2	1	23	441	463	441	463	0.99
9	13	1.2e-05	0.00078	19.4	8.3	1	23	469	491	469	491	0.99
10	13	7.4e-05	0.0047	17.0	1.5	1	23	497	519	497	519	0.97
11	13	3.4e-05	0.0022	18.0	0.4	1	23	527	549	527	549	0.99
12	13	0.001	0.064	13.4	3.0	1	23	559	581	559	581	0.98
13	13	0.00014	0.0091	16.1	2.9	1	23	586	608	586	608	0.97

Sequence Information

Coding Sequence: ATGGAGTGGTTTAAAAACTATCGTGAAATCAGGAAAGTGGCCaacatttgttgttttttttttttgaaataccGGCCTATTTTGGTTCGGAGATCATCGTGGACAATGGAAAGATCAGTTAACGATGAAATAGAAAAGAAGTGTCGCGCTTGCGCCGAACACTCGTCAGTACTGGTTGACCTCTTCTCCACGGAGATCTCTGATCCACCTGTTAGTGAAATGCTTAACTCAATTCTGCCTCAGAATTACCAAGTAATTAGAGATGCATTTCCTCATAAGATTTGCCCCTCCTGTCTCGTGTCCGCTCAAAATGCGTTCCACTTCAGGAACAAGTGCAAGAAGAGTTTTCAGTTCTTTTCCCAACTTCTCCTAATGGACGAATCCGACACGAAAACAATGGTCGCCAAAGCGGAAGAGAATCCATTGATATCTTTCGAGATTGTTGGTTGCGAGGATCCGCTTGATACAAATACGTGTCTAAACACGGAAGATCGGCTGGATCGGCTGGAAATCAATAATGATGCGGATCCAACAGACGTGTTGTCAATTAAAGAGCAGGAAACTCAACCATTGGAAGCTGTTCTTGAAATAACTTTGAGCGACGTTAAAACAGAGGAAGAAATGTCTAACGAAGAGATATTGGCCGATGTGTTGGGAACCGACTACGATGATGGTAATGATAATAATGTTGATGACGAAGTTGAAGGCGAGTCCGATGATTGTTCAGCTGAATGGTCTGAGGACCAAGATGAGCCCAGGGCCCCCAGTGATGAAGAGcacaaaaaaattgatgaGAAGAATCAATCGCTGCTGTGTACCGAATGTGGAGTAACGTATACGACGCAGAAGGCGTTGAAGTATCACATTGCTAGGCATAGAGCGCAGGATGATTCCCAAAAGGCGCACCTTTGCGACTTCTGCGGCAGAGGATTTCGGTTCAATGCGCAGCTAACAAGTCACAGGCGGAAACACACCGGAGAACGTCCCTTTAAATGCTCTCGATGTCCAAAAGCTTACACCAACCTGCCGACTCTTAAGTCGCACCTGCGCACTCATGAAGGGAAGGTTTACAAATGTCTGCAGTGCAGTAAGAGCTTTCACACGATGTCTAACCTGCGAGCGCATCAGCAGTGGCACACTGGTGACAGACCATATAAGTGTTCCGAATGTCCAAGGGCCTTCACAAAGAACTCTGGACTTAAGTTGCACAGTCGTCTGCACAAGCCTGAAAGACCCTTTAGATGCGAACTGTGCGGCAAAGGATTTGTGCAAAACCAGCATTTAATAACCCATCTTCGGGTGCACAACGAGGATCGCCAGTTTAAGTGCCCTGATTGCGATAAGTCGTTCTTCGAGAAATCCAATATGAAAAAGCATCAGCGTACCCACTCAGGCGTAAAGCCATTCAAATGCGAGGAATGCGGACATGGGTTCTCCCACAACCATCATCTAAAGAGTCACCTACGGATCCACACTGGAGAAAAGCCTTACAAGTGTGATCAGTGCGGCAAAGGTTTCTGTGCAAATCAGTCTTTGGTAAAGCATACTCTTTGGCATGTTGAAAACAATGATCGACCCTACAAATGCTCTCAATGTCCTAAAGCCTATGACAGTCCGCAGAGTTTACGGGGTCACGAAAAGACGCACAAAAAACCTGATGAGCCGAAAACGTTACACCAATGCCCTCACTGCGAAGTTAGATTTGCTCTTAAAAAGACCTTGGACAAGCATATTAGTAGTCATAAGATTCGTCCTCACCCATGCCCTCATTGCCCAGAAGGATTCTTCTCCGAGAAGAGCTTCAAAAAACACCTCAAAGTCCACAAGACGTAA
Protein Sequence: MEWFKNYREIRKVANICCFFFLKYRPILVRRSSWTMERSVNDEIEKKCRACAEHSSVLVDLFSTEISDPPVSEMLNSILPQNYQVIRDAFPHKICPSCLVSAQNAFHFRNKCKKSFQFFSQLLLMDESDTKTMVAKAEENPLISFEIVGCEDPLDTNTCLNTEDRLDRLEINNDADPTDVLSIKEQETQPLEAVLEITLSDVKTEEEMSNEEILADVLGTDYDDGNDNNVDDEVEGESDDCSAEWSEDQDEPRAPSDEEHKKIDEKNQSLLCTECGVTYTTQKALKYHIARHRAQDDSQKAHLCDFCGRGFRFNAQLTSHRRKHTGERPFKCSRCPKAYTNLPTLKSHLRTHEGKVYKCLQCSKSFHTMSNLRAHQQWHTGDRPYKCSECPRAFTKNSGLKLHSRLHKPERPFRCELCGKGFVQNQHLITHLRVHNEDRQFKCPDCDKSFFEKSNMKKHQRTHSGVKPFKCEECGHGFSHNHHLKSHLRIHTGEKPYKCDQCGKGFCANQSLVKHTLWHVENNDRPYKCSQCPKAYDSPQSLRGHEKTHKKPDEPKTLHQCPHCEVRFALKKTLDKHISSHKIRPHPCPHCPEGFFSEKSFKKHLKVHKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -