Basic Information

Insect: Drosophila erecta
Gene Symbol: -
Assembly: GCA_000005135.1
Location: CH954179.1:18995008-19000567[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0014 0.1 13.2 0.4 1 23 143 165 143 165 0.97

2 14 6.1e-05 0.0043 17.5 3.0 1 23 370 392 370 392 0.98

3 14 1.7 1.2e+02 3.4 1.7 1 23 398 421 398 422 0.91

4 14 0.058 4.1 8.1 0.8 1 23 443 466 443 466 0.96

5 14 0.0013 0.089 13.3 1.9 3 23 737 757 736 757 0.92

6 14 0.047 3.3 8.4 1.4 1 23 763 786 763 786 0.98

7 14 0.16 11 6.7 2.0 2 23 823 844 822 845 0.93

8 14 0.0098 0.69 10.5 0.7 1 23 866 889 866 889 0.97

9 14 0.036 2.5 8.8 0.2 1 23 1091 1114 1091 1114 0.93

10 14 0.013 0.9 10.2 4.2 1 23 1126 1148 1126 1148 0.98

11 14 0.0004 0.028 14.9 1.2 3 23 1155 1176 1153 1176 0.94

12 14 0.0092 0.64 10.6 3.4 2 23 1183 1207 1182 1207 0.92

13 14 0.0059 0.42 11.2 0.5 1 23 1212 1234 1212 1234 0.98

14 14 0.0085 0.6 10.7 0.3 1 23 1240 1263 1240 1263 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0014	0.1	13.2	0.4	1	23	143	165	143	165	0.97
2	14	6.1e-05	0.0043	17.5	3.0	1	23	370	392	370	392	0.98
3	14	1.7	1.2e+02	3.4	1.7	1	23	398	421	398	422	0.91
4	14	0.058	4.1	8.1	0.8	1	23	443	466	443	466	0.96
5	14	0.0013	0.089	13.3	1.9	3	23	737	757	736	757	0.92
6	14	0.047	3.3	8.4	1.4	1	23	763	786	763	786	0.98
7	14	0.16	11	6.7	2.0	2	23	823	844	822	845	0.93
8	14	0.0098	0.69	10.5	0.7	1	23	866	889	866	889	0.97
9	14	0.036	2.5	8.8	0.2	1	23	1091	1114	1091	1114	0.93
10	14	0.013	0.9	10.2	4.2	1	23	1126	1148	1126	1148	0.98
11	14	0.0004	0.028	14.9	1.2	3	23	1155	1176	1153	1176	0.94
12	14	0.0092	0.64	10.6	3.4	2	23	1183	1207	1182	1207	0.92
13	14	0.0059	0.42	11.2	0.5	1	23	1212	1234	1212	1234	0.98
14	14	0.0085	0.6	10.7	0.3	1	23	1240	1263	1240	1263	0.93

Sequence Information

Coding Sequence: ATGGCGCTGAACAAGAGGAAGAGCCCGTACATGGACGCAATTTCGGGCGCCGAAGTGGACTACAAGTTGTCATGTCGCTGCTGCTTGAAGACGAACGTGGAGTACCTCAAACTTGACTCGGTGGCGGTGGCGCGCAGTCTAGACCCGGCGGACGCATCTGAGAAGATCCCGCTCCTCCGTTGCCTGCTCTTCTGTGTGAGCGCCGAGAATGCGCCGGAGCTGCCGCAGAACATCTGCATTGAGTGCAGCAAGAGCCTACAGGTAGCCTACTACTTCCTTCAGAATGCGCTGCGTGCCCACGAGATCCTGTGCCGGAAACTATGTCCCAAGGGCTCAAGGAGACTAAATGGCACTTTGGCTGAGCAGGATAAGCTAGCGCCTGCAGAGCCGGTGTCCGAGAGGACACCGCCCCTGAAAACGATGCGGCACGAGTGTCAGGTCTGCGGTGTAGTGGTTTACAATCGCCTGGAGCTCAAGCAGCACATACGCCAGCACGCAGAGGGTCTGTCGTACAATTGCAAGCTATGCAGCTTCACATCGTTGAAGCAACGTGTTTTGTTTGAACACTATGTGACCATGCATAACATGCCCCTTAGCCAGGCAGAGGAGCACGTAAAATCAAAGCAATACCCGGCGCCAAAAGAAGAAGAGCTGAAGGCAGTGTGCACGCTTGAGGACATGGAGTTGCTGATACCCACCGTACTAAGACCGGAAGATTATgtgcagccgcagccgcataTTGATAACGCTCAACTGCAAGATATTGAGCAGCAGCTGGCCGTCAGCATGGGTGAACCCGCACCGGCAGTGGACACCCTCACCTCCACCCTGCCGCCCATGGATACGGCCAATGTTAGCATTGGCACTGAATACCTCGTTCTGCCCGATGGTTCGCTGCAACAGGTTAACGGAAGCGGCGTGGTCATCGAGTATATTGACGATAGCAAGCCGAATAATTCGGGCAACGTCAATATAAGCCTACAAAATCTGCTGTCCAGCCAAAATGAACCCATGGACATCGATGTCAACGAACTAATCGTGGAGGATACGATGCCACAGATAAGAATTAAGCCAAAACCAGCCGTTAGCGGAACATCCATTTACAAGCACAAGTGCAAATTGTGTCCGAAAACATTTTCCACTGTAGCGCGTCTAAAATCTCATCAGTTGACTCACAGCAATCTGCCCAAATTCTTTTGCGACCAATGCGATTTTTACTCATTGCGCAGCGCCGATCTTATACAGCATTACAAGATGGTCCACCATCGGTTTGATGAAAATGGTAAAATCAGAAAGGAACAGACCCCAGTTGGAGAGTCCCGGGTCTACTCGTGCGACATGTGCCTGTTCGAGACGTCCACCGTTAGCCAGTTGCGAATCCACTACAAGGAGCGGCACACGGTCCAACCCACAGAGGTACAGCTGCGTCCCAGTTGGACGGCCGAGCCGGCAGCCAGCCCTGCCCCAAAAACACCGAGAGGCATTGCCGCCAAGCAGCAGACTCCAGCTAAGATATCAAATCACATCGACATCCCGTTGGGCATTAAATATCCGCCTGTTGTTTTGGAAACGCAAGCGCCAGTACAGCAACCGGTGCATGAACCAATGCCTAACCCAGTGCAGCCAACGGAGCCAATAGCCACCACATCGACGACCATCACTGAATCGGGCGACATCAACGTAGTGGTGGATGCGACGCCGCTCTTCTATGCAGCAACCGCTAATTCCCTGATAGGGACGAACCCGGCGCCGGTGACAACGGTGGTGGAATCCAACGGAGAAGCAAGCAGTCAGGCATTTGGAATCTTTCCCGAAATCTCAGACGCCAATCTGCCGGTGAACGAAGCCGTACAGCAGACACCAGCAAATACATCAAACATTTCGATGTTTGGCGACATGCAGGACTTTATTGACAATACCGATGTAGCTGCCATATGCACCATTTCCGCGGATGACATGCCCGTTGTGGATGGTGACGACATCGTGATTGATAATAACAATATCAGTCTGGACTTTGATGCCGAGAATTTGTTCGAGGACTTCGAGGAGGAAGAGGACGCGGTGGGCGAGGATGAAGACGACGCCGACAACGATGACGAGAACGACAACAATGATGCTGCCACGGATCAAAATCTGCTGCTGACCagcgacgatgatgatgtggaCGACTTTGATGACGAGCAATCGAAGCATCTGCAGAAGCCCTACTGCATTTACTGCAATAAGAAGTTCACCAGCCAGTATAAATTTGAGAATCACATGTTTATACATCGGGGCCTGGCTCCCTATCGCTGCGAGTTGTGCACCAACCTTTACAACATGAAGCGATTGCTCATCAGACACTACAAAACTGTGCACAAACGAATGCCCACGAGGGACATGGTCCAGGCGAAGGGCGATAAGGTTTCCGTAGCCCGCACCAACATTGAAAAACTGTATCCCGGCAGGACAAAGAAACCAATGCTCATGTGCGCAAAGTGTCCGTTTGAATGCGAATCAGAGTCGGAGATGCGCAAGCATCTGAATGCCCACCATGGGATTAATGAAGGAGtATCTGAGCATGCAAACGAAGTGTTTATCATACGCAAATTACCATTCGAATGCCCGCGCTGCATTCGATCATTTGCGGCGAAGACCACACTTAGTCGCCACCTGCAGCGCAGTCATTTGGTTGATACAATTATAGAGATGCAAACGCCGCAATGCGAGGAAGCCACCACGACCACGATGGCCACATCCTCTTCAACGATTGCTGGGCCAGAAAACCCGGTCATAGAGGATATCCAGCATAATGAGGTGATGCAGACGGATGTTGGGGCTGAGAAGATGACGACGGCTGCTTTAGGCAATGGCGATGGCAATGAAGTAGCCGGCAATGATGATGGATCAGGAGAAAAAGCGGAACCGGCGATGCCAGAGGAAGAACTAGATCCCGTAACATTGGACGCAGCCACAGCGGTGACTAcaacagcaatagcagcagcaatatcagcggcggcagcagcagcggcggctaCTTCGTCAGAATCACCCATTACAACCATAACTTCATCGTCAACTAATCTCTTTCCAACGCCCACACCGTTTGATTTTGAATATGACATAATGAGAGACGAAGCCCAGCAATCGTCGCCCAATAACCATGACGTGTCCAATGCCTCATCCAGCAGCCCAATTAATGAAAGCGACAAACTGCTGTCCGCCACTGCGATGGAAACATCGCCAGCGAAGGGTTTACGCTCCAACACCCGTCTGCATCGCTCTTCCATTTACATGTGCAAGCTCTGTAGCCAAACATTTGATGAGCTTGGCAAGCTGGTCAATCATGAAATGGAGCTGCACTCCAATACGGAACGTTCACGATGGGGCTATCAGCACAAGTGTGCCATCTGCAATACAACGTACCGCACGCTCACGTTGCTCAAGTTCCATATGAAGCGACACAGCAATCGCAAATCACATTGCAAGCTGTGCCCCAAAACCTTTGTAACAGTCGCAGAACTCGAGCGGCACACGAAGGCCAAGCACAGCAGGGATAAGACGCTTCGGTGCTCTTTGGATGGCTGCCGGAAGACTTTTGGCTTCAAACACCATTTGGTACGCCATCAAAATGCCTCACATCTGAGCACGCGGTACATATGCCCCGTTTGCAATAAGGAGGAGCAATCCAATGTGCATCTGAAGAATCATATGAGCGTGCACAAGGGTGAGATAACCTACAAGTGTCCCAAGTGCGATCGCTCCTATTTGCGGCGTGGCAGACTCGCAAGCCATGTTCTTCTAATCCATAACTTGCGTCTTACCACCGAAGAGTTGGATAACATCTCATCGCAGGCTAAAAGCCAGGCAAAACCTAACGATCTTAAGGACACGACGCTCAGGGCGCACCAGGACCGCCGAAAGGATGTGGGTGGTGCAGTAGAAGAAAATGGAGAGCCCACAGGAGCTGACGATAATTCCAAGTAG
Protein Sequence: MALNKRKSPYMDAISGAEVDYKLSCRCCLKTNVEYLKLDSVAVARSLDPADASEKIPLLRCLLFCVSAENAPELPQNICIECSKSLQVAYYFLQNALRAHEILCRKLCPKGSRRLNGTLAEQDKLAPAEPVSERTPPLKTMRHECQVCGVVVYNRLELKQHIRQHAEGLSYNCKLCSFTSLKQRVLFEHYVTMHNMPLSQAEEHVKSKQYPAPKEEELKAVCTLEDMELLIPTVLRPEDYVQPQPHIDNAQLQDIEQQLAVSMGEPAPAVDTLTSTLPPMDTANVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNNSGNVNISLQNLLSSQNEPMDIDVNELIVEDTMPQIRIKPKPAVSGTSIYKHKCKLCPKTFSTVARLKSHQLTHSNLPKFFCDQCDFYSLRSADLIQHYKMVHHRFDENGKIRKEQTPVGESRVYSCDMCLFETSTVSQLRIHYKERHTVQPTEVQLRPSWTAEPAASPAPKTPRGIAAKQQTPAKISNHIDIPLGIKYPPVVLETQAPVQQPVHEPMPNPVQPTEPIATTSTTITESGDINVVVDATPLFYAATANSLIGTNPAPVTTVVESNGEASSQAFGIFPEISDANLPVNEAVQQTPANTSNISMFGDMQDFIDNTDVAAICTISADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDAVGEDEDDADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFIHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKLYPGRTKKPMLMCAKCPFECESESEMRKHLNAHHGINEGVSEHANEVFIIRKLPFECPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPQCEEATTTTMATSSSTIAGPENPVIEDIQHNEVMQTDVGAEKMTTAALGNGDGNEVAGNDDGSGEKAEPAMPEEELDPVTLDAATAVTTTAIAAAISAAAAAAAATSSESPITTITSSSTNLFPTPTPFDFEYDIMRDEAQQSSPNNHDVSNASSSSPINESDKLLSATAMETSPAKGLRSNTRLHRSSIYMCKLCSQTFDELGKLVNHEMELHSNTERSRWGYQHKCAICNTTYRTLTLLKFHMKRHSNRKSHCKLCPKTFVTVAELERHTKAKHSRDKTLRCSLDGCRKTFGFKHHLVRHQNASHLSTRYICPVCNKEEQSNVHLKNHMSVHKGEITYKCPKCDRSYLRRGRLASHVLLIHNLRLTTEELDNISSQAKSQAKPNDLKDTTLRAHQDRRKDVGGAVEENGEPTGADDNSK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00592627;
90% Identity: iTF_00619367; iTF_00591919;
80% Identity: -