Basic Information

Insect: Drosophila erecta
Gene Symbol: -
Assembly: GCA_000005135.1
Location: CH954179.1:4703138-4705016[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.4e-05 0.0038 17.6 1.9 1 23 245 268 245 268 0.97

2 8 9.7e-07 6.8e-05 23.1 1.7 2 23 279 300 278 300 0.97

3 8 0.002 0.14 12.7 0.4 1 23 309 332 309 332 0.93

4 8 0.093 6.5 7.5 0.1 3 23 342 362 340 362 0.96

5 8 0.00036 0.025 15.1 6.4 1 23 368 390 368 390 0.98

6 8 8.9e-05 0.0062 17.0 0.2 1 23 395 417 395 417 0.98

7 8 1.8e-06 0.00012 22.3 1.7 1 23 423 445 423 445 0.97

8 8 0.02 1.4 9.5 4.7 1 23 451 474 451 474 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.4e-05	0.0038	17.6	1.9	1	23	245	268	245	268	0.97
2	8	9.7e-07	6.8e-05	23.1	1.7	2	23	279	300	278	300	0.97
3	8	0.002	0.14	12.7	0.4	1	23	309	332	309	332	0.93
4	8	0.093	6.5	7.5	0.1	3	23	342	362	340	362	0.96
5	8	0.00036	0.025	15.1	6.4	1	23	368	390	368	390	0.98
6	8	8.9e-05	0.0062	17.0	0.2	1	23	395	417	395	417	0.98
7	8	1.8e-06	0.00012	22.3	1.7	1	23	423	445	423	445	0.97
8	8	0.02	1.4	9.5	4.7	1	23	451	474	451	474	0.97

Sequence Information

Coding Sequence: ATGGCCGCCGCCCAGGTGGAGGAACGCGCTGCTGCGGTGGCTCCCCATGCCGATAGAAATCCGAGCGGCGACTGGCGACATTGGTGTCGCCTGTGCGCCAAGGACGACTTGCAAGGCAACATGAATGTGTTCCTCAAGAACGAAGATTCCGGCGAGGCATCCTCTATGGAACTGGCCACCGCCATTGGCAAGTACTTCTGGGTGAATATTACTCGAGGTGAAGAGCTGCCGGAGACGATATGCAGTGAGTGCCTGTCGCTGGTCACCTCGCTGGTGAATTTCTCGGAACGGATTACCCGCGTGCAGAAGCTTTACTGCATCCTGCAAAGCACGCCCAACCACGAGAGCCCAAATCTCCACGAACTCCGCTCTAAATTTGGTTTGCTGGACGAGGAGACGCTGACTGAGGTCCACTATGTGGATAAGAAGCCAAAGTTGGATGAACAGCTTGAGTTTCTGCCAGAGGAGTCGACTTACGAGCTGGAAAACCCACTGACGCCAgaggaaaagcaggaaaagATAGATCAGGAGCAGGATCAGCCGGCGGAGGAGCGAGAACAAGAGGAGCCAGATGAACGGGATGCCGACTACGATGCGGATGAAGATGGCGTACTGATGAACCTGTGTGATGCCTATGGCATTCAGGAGGATGACTCTTCCGCGGGTAGCTTTGGCGACTCCTCGCCGAGTCAAGAAAAAGCTGGACAGGATGCAGCAGACTCCGAAAAAAGACACCAGTGCAGTGAGTGTTTGCGAAGCTACGCCACGGCCAAAACCCTGCAGCGTCACCTGCGACAGGATCATGGTCAGACTGAGCCCCCAACCGAGCAGCTGCAATGCCCGGATTGCCCCAAGAAGTTTCGCCTACACTACCAGCTGGAAAGGCACATGAAATGGCATGTGCCCCTGCCCAAGCGGAAGCAGTACGCCTGCAGTAGTTGCGACAAGAAGTTCGCCACCAGTGCATCCGCCCAGCAGCACGAACAGTACATGCACCTGGATGAGCGGCCGAGGCCGGTGATTTGCGAACAGTGCGGCGTGGGTGTGCACTCGATGAGCGCGCTCAAGGAGCACGTCCTGAAGCACACGGACTATGCCCCTTTCGAGTGCGAGGTGTGCAAGAAGTGCTTTAAGTCGGCCAATCGCCTAAAACACCACAAGGAGACGCATGATCCGCACAAGTACATCTGCCCGGAGTGCGGCATGCAGCTGAATTCGCGGACCACTTTGAATCGCCACCGTCTGGTGCACACGGACCAGATGCAGCACAAGTGTGACTATTGCGGCCGTGAGTTCAAGCGGGCCAAGGCGCTGAAGAATCACCTCATCCTGCATACTGGACTCAAGCCTTACTCCTGCGACTTTTGCGACCGCACCTTTGCCAACGGCTCCAACTGCCGCACGCACAAGAAGAAGTCACATCCCGAGGAACTGGCTGCCCAAGAGGCGGCGGGCGGCGGCAGGTCGCACAACAGAAATATACCCAAGCTGGAGGCACTCAAGGCGTTCACCAAGAACAAGGACAACCTGTCGCCGGTGGCTACCAAACAGAGCGGGTGCTTCGCGTTCGGGAAAAAGCCAAGGCAAACCATCAAGGATACTCCGGCTTCGAATCCCGCCTCCACCCAAGATGCTCAGCCTGAACCAGCGCCTGAACCCGGAGGGGAAAGCGTCGCCCAAGCCGATCCCCCAGCTGCGGCTATACCCACGTTAGATAATATTTACAACCATATCATGATTGACTATCGCTGA
Protein Sequence: MAAAQVEERAAAVAPHADRNPSGDWRHWCRLCAKDDLQGNMNVFLKNEDSGEASSMELATAIGKYFWVNITRGEELPETICSECLSLVTSLVNFSERITRVQKLYCILQSTPNHESPNLHELRSKFGLLDEETLTEVHYVDKKPKLDEQLEFLPEESTYELENPLTPEEKQEKIDQEQDQPAEEREQEEPDERDADYDADEDGVLMNLCDAYGIQEDDSSAGSFGDSSPSQEKAGQDAADSEKRHQCSECLRSYATAKTLQRHLRQDHGQTEPPTEQLQCPDCPKKFRLHYQLERHMKWHVPLPKRKQYACSSCDKKFATSASAQQHEQYMHLDERPRPVICEQCGVGVHSMSALKEHVLKHTDYAPFECEVCKKCFKSANRLKHHKETHDPHKYICPECGMQLNSRTTLNRHRLVHTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKSHPEELAAQEAAGGGRSHNRNIPKLEALKAFTKNKDNLSPVATKQSGCFAFGKKPRQTIKDTPASNPASTQDAQPEPAPEPGGESVAQADPPAAAIPTLDNIYNHIMIDYR*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578738;
90% Identity: iTF_00591911;
80% Identity: -