Basic Information

Insect: Drosophila erecta
Gene Symbol: gfi1b
Assembly: GCA_000005135.1
Location: CH954181.1:15605556-15607602[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.7e-06 0.00047 20.5 1.1 1 23 317 340 317 340 0.95

2 8 0.0037 0.26 11.9 5.8 2 23 351 372 350 372 0.97

3 8 1.6e-06 0.00012 22.4 0.7 2 23 382 404 382 404 0.92

4 8 5.2e-05 0.0036 17.7 0.3 1 23 410 432 410 432 0.97

5 8 6.6e-06 0.00047 20.5 0.8 1 23 438 460 438 460 0.98

6 8 0.00065 0.046 14.2 1.6 1 23 465 487 465 487 0.98

7 8 3.9e-06 0.00027 21.2 0.8 1 23 493 515 493 515 0.97

8 8 0.0069 0.49 11.0 3.2 1 23 521 544 521 544 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.7e-06	0.00047	20.5	1.1	1	23	317	340	317	340	0.95
2	8	0.0037	0.26	11.9	5.8	2	23	351	372	350	372	0.97
3	8	1.6e-06	0.00012	22.4	0.7	2	23	382	404	382	404	0.92
4	8	5.2e-05	0.0036	17.7	0.3	1	23	410	432	410	432	0.97
5	8	6.6e-06	0.00047	20.5	0.8	1	23	438	460	438	460	0.98
6	8	0.00065	0.046	14.2	1.6	1	23	465	487	465	487	0.98
7	8	3.9e-06	0.00027	21.2	0.8	1	23	493	515	493	515	0.97
8	8	0.0069	0.49	11.0	3.2	1	23	521	544	521	544	0.96

Sequence Information

Coding Sequence: ATGTCGGTTATTATCGCAGAAACTCAAGCCGTCAACCGAGATTCAACAATTTGGCACCAATGGTGTCGCCTGTGTTCCAAGGAGCATCCGAGCAACCAAAATGTGTTCTTCCGGGAGGCGAAACAAAACTCCTGGGCGAGCACAATGGCCATGACCATTGGCAAATACTTTTGGGTCGATATCAAAAGGGAGGATGAGCTGAGCAATTTTCTGTGTGCCGAATGCTTCACATTGATGGACTGCCTCATCGACTTTTCGGAGAGGGTTCGCAAAGTGCAGATCCTCTTCAGCAAATTGCAGTTGTTAAAGCCTGATCATTTGACGGATTATGAGCAAATGCGAGAGGAGTGCGGTGTAGCCACTGATGGATGGAAGCATATAATGCTCAACGCAGTGGAGGCAAATCTCCAGAATGAGGAAGAATGCATCAGTGAGGATCAACCAATAGTCTGCCAAACAGTAACATCCAGTAGAATGGAAGGTGAAATCCTAATGATACCAAATTTGTTGGTGGAAGAACAATGTCTTCAGGAAAAACAAGACTTTCTTAAAGAGGAACATATTGTCGAAgaagaaatgcaaatttctgaAATGGAAGAGGACGTCTTAGAAGAAGAGGTGGAAGACCTTGCGGAGGAAGAGGTTGAGACTGTGGAGGAAGAGATCGACACTGTTGGGGAAGTGGTAGATCCCCAAGACGCTTCAGATTGTTCAGTGGAGCACATGACAGAGGAACGCTATATCGAGGAGTCGCAGATTATTGAAGAAAGCCAAGTCTCAGATTTTAATATGGAAACATATGAAATAGTACAACACGATCCGCAAAAAGAATCCGAAGAAACGAAAGACACTGTAGAATCCATGGAATCAAGCGAGGATACCCAGGAAGATATCTCCCCAGAGCATGTGACCTATGACGAGAATGAAATACCCGAGGAACCAGCCATGTATAAGtgcaatatttgcaaaaaGCCGTATAAGAAACCCAAAGCCTACAAGCGTCACATGGAGGAGGTTCACAACACTGTGGCCGAGGATCTGCCACAGTTAGAGTGTAATCAGTGCAAACTATGCTTCCCAACAGTCGCCCAGCTGCACTCCCACCACCGAACTCATGTCCGAGTCAAAGCAAAGACAGATAACTCCTGTCCACACTGCGAAAAGCGCTTCACAACCCCGGGAACACTCAAGCGGCATATAGAAGGCATCCACAACCAAATAAAGCCCTACGTTTGCGACCTCTGCGGCAAGAGCTTTAACTACATTACTGGACTGAAGGATCACAAACTTGTGCACACGGATGAGTGTCCCTTCGAGTGTCCCGTGTGCAAGCGACGCTTTAAAAACAATGCGAGGTTAAAGATCCATTTAGATACGCACAGTGCCGATATCTACGAGTGCACTGTATgcggcttgaagctaaaaacCCGTCGCACGTTCAACAAGCACAAATTGGTGCACTCAGATAAACGTCAATTTAAGTGTGAAGTCTGCGGATCGACGTTCAAGCGAAGCAAGACGCTAAAGGCACATCTCATCCTTCACACCGGCATCCGGCcgtataaatgcaatttttgcgGAAGAGACTTCGCCAATGGCTCCAATTGTCGATCGCACAAACGCCAGGCGCATCCCAAGGAACTGGCCGAAGAGGAAGCGCGCGGAGTGACACGTTCCACACTTCTTCCAATGCTGGACGAACTCACGAAGGCGTCCAAGCTTTTAAAAACACCCGCAGGACCTTGCAAAGTAAAGGGTAGTAGGCCAAAAGTTCCGCCTAAAAAGCAAGATAATGACACTGAATCTCCAACGAAAGACACCGACGGTGCCATCCTCTACGAGCTGGTCGAGGAGCTTGATTATTCCTaa
Protein Sequence: MSVIIAETQAVNRDSTIWHQWCRLCSKEHPSNQNVFFREAKQNSWASTMAMTIGKYFWVDIKREDELSNFLCAECFTLMDCLIDFSERVRKVQILFSKLQLLKPDHLTDYEQMREECGVATDGWKHIMLNAVEANLQNEEECISEDQPIVCQTVTSSRMEGEILMIPNLLVEEQCLQEKQDFLKEEHIVEEEMQISEMEEDVLEEEVEDLAEEEVETVEEEIDTVGEVVDPQDASDCSVEHMTEERYIEESQIIEESQVSDFNMETYEIVQHDPQKESEETKDTVESMESSEDTQEDISPEHVTYDENEIPEEPAMYKCNICKKPYKKPKAYKRHMEEVHNTVAEDLPQLECNQCKLCFPTVAQLHSHHRTHVRVKAKTDNSCPHCEKRFTTPGTLKRHIEGIHNQIKPYVCDLCGKSFNYITGLKDHKLVHTDECPFECPVCKRRFKNNARLKIHLDTHSADIYECTVCGLKLKTRRTFNKHKLVHSDKRQFKCEVCGSTFKRSKTLKAHLILHTGIRPYKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTRSTLLPMLDELTKASKLLKTPAGPCKVKGSRPKVPPKKQDNDTESPTKDTDGAILYELVEELDYS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596818;
90% Identity: iTF_00591862;
80% Identity: -