Basic Information

Insect: Drosophila erecta
Gene Symbol: -
Assembly: GCA_000005135.1
Location: CH954178.1:3992122-3994678[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.015 1 10.0 2.6 1 23 291 313 291 313 0.98

2 11 1.5e-06 0.0001 22.6 0.7 1 23 319 341 319 341 0.99

3 11 0.00035 0.025 15.1 2.5 1 23 347 370 347 370 0.97

4 11 0.37 26 5.6 3.9 1 20 376 395 376 398 0.95

5 11 0.0027 0.19 12.3 1.8 1 23 404 426 404 426 0.98

6 11 4.3e-05 0.003 18.0 1.2 1 23 432 454 432 454 0.98

7 11 0.00082 0.058 13.9 3.6 1 23 462 485 462 485 0.97

8 11 0.031 2.1 9.0 0.7 2 23 492 513 491 513 0.96

9 11 0.00046 0.032 14.7 1.1 1 23 519 541 519 541 0.98

10 11 1.5e-05 0.0011 19.4 1.8 1 23 547 570 547 570 0.96

11 11 1.4e-06 9.8e-05 22.6 2.6 1 23 584 606 584 606 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.015	1	10.0	2.6	1	23	291	313	291	313	0.98
2	11	1.5e-06	0.0001	22.6	0.7	1	23	319	341	319	341	0.99
3	11	0.00035	0.025	15.1	2.5	1	23	347	370	347	370	0.97
4	11	0.37	26	5.6	3.9	1	20	376	395	376	398	0.95
5	11	0.0027	0.19	12.3	1.8	1	23	404	426	404	426	0.98
6	11	4.3e-05	0.003	18.0	1.2	1	23	432	454	432	454	0.98
7	11	0.00082	0.058	13.9	3.6	1	23	462	485	462	485	0.97
8	11	0.031	2.1	9.0	0.7	2	23	492	513	491	513	0.96
9	11	0.00046	0.032	14.7	1.1	1	23	519	541	519	541	0.98
10	11	1.5e-05	0.0011	19.4	1.8	1	23	547	570	547	570	0.96
11	11	1.4e-06	9.8e-05	22.6	2.6	1	23	584	606	584	606	0.98

Sequence Information

Coding Sequence: ATGCCTAGGAGGACAAAAAAGTACGAGGACCCTGAGGATCTGCAGTCCTTCCTCAACAATTTCCATAAGGAAATCGAAGGCAACAGCGATGAGAAGGTGGTGAACACAATTTTGGAGGCTATTAGTGCCGAGGCCATCGACTTGGATGAGAATGATGAGGAGGCGGGTGGATCGAAAccggtggaggaggaggtgctgGAGCAGTTGGCTGATTTGGAAGAAGCGGAGGAGGAAGACGACGAGGACAAGTACTTCATAGATGACGAGGGCAACTGCTACATCAAGACTacacccaaaaaacaaaaggagcttcaaaagcagctcaaacaggCTGGCAAGCCGGGGAAAGCCACACGTTCCGTGGTCAGTACAGCCACCAATAAATcCATCAATTTGCACCCAGCCAAATCGACACCACCCAAGGTGGCTATTTCAAAACCTGCCCCAGAACCCAGGGCAATTAGCGTTCGCCCTGCCCGAGCTGCTGCAGCCAAGGCGAAGCAATCTGCGCTGCCACCCCCGCCTGCAGCAGTGGTCAAAGTACCGGCAACCAGGGGCAGGCCAAGAAAGAACACTGTCATACCGAAGTCTGAACCTATTGATTTGGAGCGCGAGCTCGAAGAGCTGGTAGATGAGCCCGACATCAGTTCCATGGTGACCCAATTGGCGGACTATGCCGTAGACGAAGCTGCCGTAGATGCTGCCTCCGCTACCCTGGCGCCAAACGAGGCTGAAGTATACGAGTTTGAGGACAATGCGACAGAGGATGAGAGTGCCGACAAGAAGGACGTAGACTTTGTGCTTAGCAGCAAGGAGGTGAAGCTGAAGCCAGCTTCTACCAGCCAGAACTCAAATGCTTCCGGACATAAGTACTCATGTCCACACTGCCCGTATACGGCGAACAAGAAGTTTCTGATCACGCGCCACTCTCGGAGCCATGACGTTGAGCCTTCATTCAAGTGCTCCATCTGCGAGAGGTCCTTCCGATCGAACGTGGGTCTGCAAAACCACGTAAACACGCACATGGGCAAGAAGCCGCACAAGTGTAAGCTCTGCGAAAGCGCCTTCACCACCAGCGGCGAGCTGGTCCGTCACACGCGCTACAAGCACACCAAGGAAAAACCGCACAAGTGCACGGAGTGCACCTACGCCAGTGTGGAACTGACAAAATTGCGCCGTCACATGACCTGCCATACGGGCGAGAGACCATATCAATGTCCACACTGCACATACGCCTCGCAGGACATGTTCAAGCTGAAGCGACACATGGTGATCCACACGGGCGAGAAGAAGTACCAATGCGACATCTGCAAGTCACGATTCACGCAATCCAACTCCCTGAAGGCCCACAAGCTCATCCACAGCGTGGTCGACAAGCCCGTCTTTCAGTGCAACTTCTGTCCGACGACTTGCGGCCGGAAGGCTGACCTGCGCATTCACATCAAACACATGCACACCTCTGATGTGCCGATCACATGCCGGCGCTGTGGCCAGCAGCTACCCGATCGCTATCAATACAAGCTGCACGTAAAGTCGCACGAGGGCGAGAAGTGCTACAGCTGCAAGCTCTGCAGCTACGCTTCGGTCACCCAACGCCACCTGGCCTCGCACATGCTCATCCACCTGGACGAAAAGCCGTTCCACTGCGATCAGTGCCCGCAGGCCTTCCGCCAGCGCCAATTGCTGCGTCGCCATATGAATCTCGTACACAACGAAGAGTATCAGCCACCAGCACCGCGCGCTAAACTGCACAAGTGCCCGAGCTGTCCACGGGAGTTTACCCACAAGGGTAATCTAATGAGACACATGGAGATTCACGACGATTCGGCGAACGCTCGCGAAAAGCGGCGCCGCCTTAAGTTGGGCAGAAATGTGCGACTCCAGAAGGATGGCACTGTCATCACGTTGGTCAAGGAGCAATTTCTGAATATGGACCAGGAGGACAACGAAGAGGAAGACAACCCAGAGAGCTATGACCTAGCTGAAATCGAGCCTGAGAACTCGGAGGGTGAAGACGCTGAAGATGTGGAAACCATAGTCAGTGATCCGATACGGCAGAGAGTCAAGCCCGCACCTGTCATTATCAACAAACAGGCAAGGCTTGCCGCCTCCGAAAAGCAGCCGATGATCATCAATCAACGACTCCGAAGTCAGCGGGGCACCAAGACGTTCCACATCAAGGAGGAGCCGGATAACTCCGACTTCACCGTGGAATTGCAAGGTGATGACGGCGAGGTTATGGTCGTTGAGCTTGTTAATGGCGACGAGGAGGTGTTGGTCAAGCACGAGCCGAGCGCCAACTCCAAGATTAGTGCCAAAAACTGCTTTGGTTTCGAGGACGACGATGATTATGAGGAGTATGGCGAAGCGGAAAATGAAGTTGATGGCGCTTCGCAGGAGTTTTTGCAGCTGATGGATATGATTGAGCAGGATTCTTAG
Protein Sequence: MPRRTKKYEDPEDLQSFLNNFHKEIEGNSDEKVVNTILEAISAEAIDLDENDEEAGGSKPVEEEVLEQLADLEEAEEEDDEDKYFIDDEGNCYIKTTPKKQKELQKQLKQAGKPGKATRSVVSTATNKSINLHPAKSTPPKVAISKPAPEPRAISVRPARAAAAKAKQSALPPPPAAVVKVPATRGRPRKNTVIPKSEPIDLERELEELVDEPDISSMVTQLADYAVDEAAVDAASATLAPNEAEVYEFEDNATEDESADKKDVDFVLSSKEVKLKPASTSQNSNASGHKYSCPHCPYTANKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHVNTHMGKKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNFCPTTCGRKADLRIHIKHMHTSDVPITCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASHMLIHLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPAPRAKLHKCPSCPREFTHKGNLMRHMEIHDDSANAREKRRRLKLGRNVRLQKDGTVITLVKEQFLNMDQEDNEEEDNPESYDLAEIEPENSEGEDAEDVETIVSDPIRQRVKPAPVIINKQARLAASEKQPMIINQRLRSQRGTKTFHIKEEPDNSDFTVELQGDDGEVMVVELVNGDEEVLVKHEPSANSKISAKNCFGFEDDDDYEEYGEAENEVDGASQEFLQLMDMIEQDS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596809;
90% Identity: iTF_00539814; iTF_00596809; iTF_00592544; iTF_00591861; iTF_00607909; iTF_00619316;
80% Identity: -