Basic Information

Insect: Drosophila erecta
Gene Symbol: ZNF526
Assembly: GCA_000005135.1
Location: CH954181.1:10558798-10560829[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.094 6.6 7.4 0.3 1 21 326 346 326 347 0.95

2 10 7.2e-07 5.1e-05 23.5 0.3 1 23 355 377 355 377 0.98

3 10 5e-05 0.0035 17.7 0.6 1 23 380 403 380 403 0.92

4 10 8.1e-07 5.7e-05 23.4 1.0 2 23 410 431 409 431 0.98

5 10 6.1e-08 4.3e-06 26.9 1.3 1 23 437 459 437 459 0.97

6 10 2.4e-06 0.00017 21.9 1.2 1 23 465 487 465 487 0.99

7 10 0.00062 0.043 14.3 2.9 1 23 493 515 493 515 0.98

8 10 0.001 0.073 13.6 0.3 1 23 521 543 521 543 0.98

9 10 9.7e-05 0.0068 16.8 3.7 1 23 549 571 549 571 0.99

10 10 0.0031 0.22 12.1 0.0 1 23 577 599 577 599 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.094	6.6	7.4	0.3	1	21	326	346	326	347	0.95
2	10	7.2e-07	5.1e-05	23.5	0.3	1	23	355	377	355	377	0.98
3	10	5e-05	0.0035	17.7	0.6	1	23	380	403	380	403	0.92
4	10	8.1e-07	5.7e-05	23.4	1.0	2	23	410	431	409	431	0.98
5	10	6.1e-08	4.3e-06	26.9	1.3	1	23	437	459	437	459	0.97
6	10	2.4e-06	0.00017	21.9	1.2	1	23	465	487	465	487	0.99
7	10	0.00062	0.043	14.3	2.9	1	23	493	515	493	515	0.98
8	10	0.001	0.073	13.6	0.3	1	23	521	543	521	543	0.98
9	10	9.7e-05	0.0068	16.8	3.7	1	23	549	571	549	571	0.99
10	10	0.0031	0.22	12.1	0.0	1	23	577	599	577	599	0.95

Sequence Information

Coding Sequence: ATGGATGTGGACAAGATCTGCCTTACCTGCCTGAGTTCCACGGGACCCCTCCTGTCCATTTACGACGGCGGATCCGGCAGCTGCCTGGCGGACATGATCCGGGAGTTCACAAAAACCAAGCCCCGCCGCAACGATAATCTTCCCGAAAAGGTGTGCCTGAGCTGTTTAAGTGAGATCTCCAACTGCTACACCTTTAAGATGAAGTGCGAGAACTCCAGTCGCACTCTGCGCCAGTTGCTGCCGAATGCTCTTCCGGAGGAGCCCGATAACAAGGTGTCCATTAGTTGTCCAGTGGCCACGACAGACCAGGCTGTGCAGACCACTAGTTGGGAGCCCGACAGATGCACTGTCTCCGTGCAAACGGACGCAGTGGCTACCACAGACGCCGAACAGAATACCAGCCTAGTTAAGTCCACGATTTCAGTGGACCTGGACTACGAAGACGAGGGCGAAGTCTTCGACTATGAGCTGCCGGATGAGCCTGTCGAAAAGACCACCAGCCTCATTCTCCAGGTTCAGGGAAATTTGAAGGACGAAAAGGAAGTGGTGTTTACCCAAACCAATGTTATTTACGAAGGCGACGACAacgagctggagcagcagatTAGGGAGTGTAATCTAGCCATTTTTGAAGGTGTCGACAACGAGGCGGAGATCATCACAGTAACCGCTCCTCAGGTTACCACCAGAAAGAGCGCTGCCAAACTCTTAACGCAGCAGGAAAACGAAAAGCAGGAAACTCCTAAGGATGAAGCCCGCGAAATACAGAAGGAACACGTGCCTCAGACAGCTAAGCGCACCTCACGGCGGCGCGGAGGTGTCAAGCAGGATGTGCCAACTACCCCTACTTCAGAAGCAGAGCCTTCCTCCAAACAGCTTCGGTTGGGAACACAGCGAAAACTGTGCGCGCCAAGAACAGGAACAGTAAACAGCCCAAGCACCACGTCAGGAACAGCCATTACCCCTGAGCTAAAGTACCATTGTGATCGTTGCAACGCGGGATTCGCGCTGGAGAAATCTTTGATGATCCACAGACGCCAAAAGGGTTGCATTAACCGCAACTTCAAGTGCAATGAGTGCGAAAAGGTCTTTGTGTCGCCGGATCACTTGGCAGAACACCAGGCCAGTCATGGTGCCCACAATTGCCCGGAGTGTGGATTACGTTATGACTCCAAGGAGCAACTTAGCAAGCACATGGTGCAGGGCCACAAGCGGAATCTACGGAATCAGTGCAAAATCTGTCAGAAAGTTTTCACCATGCTATCGACGCTGCGTGATCACATGCGCATCCACACTGGCGAGAAACCCTTTATGTGCAATATCTGCGGAAAGAGCTTTACACAGAACGCCAATTTGCGCCAACACAAACTGCGTCACTCCGAAACCAAAAGTTTTAAGTGCGAGCTGTGCCCGCACTCGTTCGTTACCAAGGCGGAACTGACCTCTCATGCCCGCACCCACACAGGCGACAAGCCCTTCGAATGCGAGGTGTGTTTGGCCAGATTCACCACCAGCTGCTCCCTGGCCAAGCACAAACGAAAACACACCGGCGAACGGCCGTACGCCTGTGATCTCTGCCCCATGAGATTCACTGCCCTGAACGTGCTAAAGAACCACAGAAGGACGCACACAGGTGAGCGGCCGTACGTCTGCCCATTCTGCTCGAAAACCTTTACGCAACGGGGTGACTGCCAGATGCATCAGCGTACCCATCAGGGCGATCGTATCTACATTTGTCCGGTGTGCAATGAGGAGTTCAAGTCGATGCCCGAGATGCGAATGCATTTGGCCGGGCACGAGCAGCACGACAAACGCCTGGTGCATTTCACCTTTCTTAGCAACAAAGAAAACGGAAGCGGAGCCCTTGAAGAAGATCTTAATGAGATGGCCGAATCTGCACTTATGATATAA
Protein Sequence: MDVDKICLTCLSSTGPLLSIYDGGSGSCLADMIREFTKTKPRRNDNLPEKVCLSCLSEISNCYTFKMKCENSSRTLRQLLPNALPEEPDNKVSISCPVATTDQAVQTTSWEPDRCTVSVQTDAVATTDAEQNTSLVKSTISVDLDYEDEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYEGDDNELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENEKQETPKDEAREIQKEHVPQTAKRTSRRRGGVKQDVPTTPTSEAEPSSKQLRLGTQRKLCAPRTGTVNSPSTTSGTAITPELKYHCDRCNAGFALEKSLMIHRRQKGCINRNFKCNECEKVFVSPDHLAEHQASHGAHNCPECGLRYDSKEQLSKHMVQGHKRNLRNQCKICQKVFTMLSTLRDHMRIHTGEKPFMCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGDRIYICPVCNEEFKSMPEMRMHLAGHEQHDKRLVHFTFLSNKENGSGALEEDLNEMAESALMI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505549;
90% Identity: iTF_00591836;
80% Identity: -