Derc014813.1
Basic Information
- Insect
- Drosophila ercepeae
- Gene Symbol
- -
- Assembly
- GCA_018150545.1
- Location
- JAECWL010000161.1:15393688-15402959[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0005 0.035 14.4 2.0 1 23 735 757 735 757 0.98 2 8 8.5e-05 0.0059 16.8 1.4 1 23 789 811 789 811 0.97 3 8 0.061 4.3 7.8 0.5 1 19 819 836 819 842 0.81 4 8 0.00018 0.012 15.8 0.1 3 23 849 870 848 870 0.96 5 8 0.00016 0.011 15.9 3.5 1 23 876 898 876 898 0.97 6 8 0.023 1.6 9.1 0.2 1 23 905 928 905 928 0.95 7 8 0.00021 0.015 15.6 2.2 2 20 935 953 934 956 0.91 8 8 0.0091 0.63 10.4 4.7 1 23 962 985 962 985 0.93
Sequence Information
- Coding Sequence
- ATGGATAACAAAACTACACAGTTGGATTTTAAATTACTGGTGGATCAGTCACTAAATCTACTGGATAGCCTCAACACGGCATTGCGGTGCGATGCCATTCAGTTCTTGCTGCAGACGCTTAAGTGCAAGTACCCGGATGCCTGCGACCAAGTCGTCAGGAATCTGTTCAGCCACATAACCAATAGCAATGGAGGAGGAGCAGGCGAGGCGGGACAGCAAGAGCTGGCGAGGACCAAGCAACTCCAGCTCCAGCTGCTGCTGACCGCCAAAAAGGAGAAGCGGGAGGGCGCAGAGACGGAGATCAAGCGCGAGAAGGCCGAGGAAGAGGCGGGCTCGACGGATCTGAACCAGAACTTTGAAAAGATCCTCTGCAAAGAGGAGTTTCTGTGCCTCGAGGAGGAGGAGGAGGATTTCCTCGACGATGTGGATACCCAGAACTCGTCTTCCCTGCAGTTCCATGCCGGCAACAATGTCGATGGTTTGTCCCTGGGTCCCGGTGATCCTCTGGACCTGATCCAGACCGGCGGCTCCTCGCTGCTGGTGAAGCGAAAGTACACGGCCACCTTCGCGGATGATGAGGACCAATTGGGCGCGGATGCGGAGGAGGCGAGCAATACCAGCAGCAGCAGCGATGGCAAGCTGGTCAAGCGGAAGCGCACTAACAACATGCACCTGACCATAGCCAGTGTGCGGCGGAAAGAGAAGCGCTCCACCCTGGGCGATGGCTATGTCTTTCACGAGGACAGTCAGTACACCATGCACTACCATCACAGCACCGGCGAGTTTAGCGAGCGAGCCTTCAAGGCTCAGTTCCGGGCTCTGCTGCGTCTGGCGCTCAGCCAGCACCACAAGCCCTTCCTCAGGCAGTTCTACGAGAACTTTGTGGTTACCGGTCGCCTGCTGGGCACCACGCCGTCGGCCCGAATGCTGAAGGAGCTGCGCGAGCAGCGCCTGGAGGAGTGGCGGCGTCAACGGGAAAGACGCCAGTTGCTTAGCCTGATGAAGCAGAGTGAGCTGGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATTTCCTTCGGTGACTCAGAGCTCGAATCCGAGACGGAGTCACAGCTCTCGTCCGCCGCCCAAGAGATTATGAAGTTTGAGGAGTTCATCGATGAAGGTGTAGGCGCAGGACGTCTCATCGATGGGCTGGAGATGGAGCCAGAGATAGATGACATGCTGGGCGGCGCTGGTAGTGCCCTGGGCAGTGTGAACAGTGCTAGCGGCCATAGCAGCAATAGCAGCAGCAGCGGGAGTGGGAGCGGCAACGGAAACGGCGTCAGCGGGGTGGTCCTGGAGAACAATAGTCATCATTCGAATCACCTAAGCGCCAGCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCACCACTTGCCAATGTCCATGCCCGTAGAGAATATGGATCGGAAGGAGGGCCAGCTAATGCCAGGCGGTATTTCTGGCCTCCCTAATGAGATACAAATGCATCAGCAGCCAAATCGCTACAACTCAAGCAATAATCCTCTATCCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATGATGCAGGGCCAGTTCCCGCCGCATGGAACTTCTATGATGGGCAACCGGCAAATGCCTGCGCTGGCTGCCTTGTCGAATTTGGGGGACAATGTGTCGGTCGGTGGACAGTTGAACTCGTCCCTCGAGTTGGACGACAATGACTTGTCGCCAGACGAGGACGACGACGAACTCGACCATGACCTCGACGAGCTGGACGCGGCCAAGCAACAACTGATCGACGGCGGTAGCAGTAGTAGTACCTCATTACAGGCACCTCCCTCGCAGCTGGGCAGCGTTGGAAGTGGCAGCCAGACGCCCGGAAGCAAAAAGGACAAGCCCAACTACAATTGCCTGCTATGCCCGAAGTCTTACCGAAAGCGCAAGTCCTTGCTGGACCACTATAAGATGCATCCTGGCTACTGTCACGATTGTGGTCAACCTAATGGAAACACCCTGGAGGAAATCATTCATCACAATAGGACTATGCATGTGAAAGAGTTCCCGTTCGTGTGCGAGACCTGTGGGGAATCCTACTCTCGCAAGCAACAGTTCCACGCCCATGTTGAGTCGCACAACAAGAAGGAAATCAAAACGTTTCCTTGCGGCGAATGCGGGCAAAAGTTTCCGCAGAAGAAGCTGCAACAGCACTTCGAAGAGACGGGCCACAAGGCCGACGGGGCCATTTGCGAGGTGTGCGGCGAAGAGTTTACATCAAAAAACGCCCTGTACCAGCACATTATCCGTGTCCATAAGCGGGACAACTTCTTCGAGTGCCACATTTGCCATAACCGATTCACTCTGAAGGCCAACCTGGAGCGGCACGTGCAGCTGCATACCGAGGTCAAGCGACCTTATGTCTGCGACCTGTGCGGCTCCTCCTACTTCACATACCCTGCGCTCAAGGAGCACTACAGTAACGCGCACGTCGATGTCTCCGAATGCAAGTGCACGCTGTGCGGCAAGCGCTTTGGATCGGCCAAATCGCTTCAGAGGCACCTGCCGTCCCATTCGGAAGAGCGCCCGCACTCCTGCAACTACTGCGATCAAACGTTCAAATGGAAGACTCACCTGGTGCGACACAAGCAAGCGATGCACGGAAACGAACCGGTGCCGCCTAAAAAAGGAAAGCAGCGCTTCCCCAAGGCTAACGAAGAAGAAATGGCTTCGCTTCCAGATATGCCAGGACCTCCTCCTGTTAAGGCCAGTAAAAAGTCAGTGGCGAACAAGGCCAAGGCGCAAGCAGTGGCCGTCGCTTCCGTCACTTCCCAGCAGCAACTGAAGGGGGCAGCAGCTACGCCAACACCGCCGCCGCCTGTCTCGACGACTCCAGGGTGCCTGCAGCAGGATCAATTCAATGCAGCCATGGTTAGCAGCAACAGTTCGCAGTCCTCCACGGCGTCCACGTCACAACACTCAGTGTCAACGAGTGAATCTCAGCAGAATTCCATGTACAGTCAGAGCTTTAATGCGGAGAAACTGCAGGCTGCAGGACAACAGCAACCACAGCAACCAAACCCGCTGCACCAGCAACATCCGACGCCGCCGCCCACACAACAGCAGCAGCAGCAACAACAACCGAGAGTCGGCTCCGCTGAGATGCATTTGCAACGCATGAATAGCTTTACTCAGGAAGGGCACCTGCACGGGCCACAGGCCCAGCAACAGCAACCTATGCACCCGCACCTTCTGCCACCTCCAGCGCCGCATGGCAGCGTCTACGATCGGACGGGAGTTGGTGTAGGTGTCGGTGTGGGGTACTCCATGCTAGGAGATGACCCCAAGGGCGTGCTGCCACCAATGATGGGAATGATGCAGCAGATGCCGCCGCATGGCCAGCAACCAGATTTGATCTACTACCCAGTGAAGAACGATTGA
- Protein Sequence
- MDNKTTQLDFKLLVDQSLNLLDSLNTALRCDAIQFLLQTLKCKYPDACDQVVRNLFSHITNSNGGGAGEAGQQELARTKQLQLQLLLTAKKEKREGAETEIKREKAEEEAGSTDLNQNFEKILCKEEFLCLEEEEEDFLDDVDTQNSSSLQFHAGNNVDGLSLGPGDPLDLIQTGGSSLLVKRKYTATFADDEDQLGADAEEASNTSSSSDGKLVKRKRTNNMHLTIASVRRKEKRSTLGDGYVFHEDSQYTMHYHHSTGEFSERAFKAQFRALLRLALSQHHKPFLRQFYENFVVTGRLLGTTPSARMLKELREQRLEEWRRQRERRQLLSLMKQSELEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXISFGDSELESETESQLSSAAQEIMKFEEFIDEGVGAGRLIDGLEMEPEIDDMLGGAGSALGSVNSASGHSSNSSSSGSGSGNGNGVSGVVLENNSHHSNHLSASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHHLPMSMPVENMDRKEGQLMPGGISGLPNEIQMHQQPNRYNSSNNPLSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMMQGQFPPHGTSMMGNRQMPALAALSNLGDNVSVGGQLNSSLELDDNDLSPDEDDDELDHDLDELDAAKQQLIDGGSSSSTSLQAPPSQLGSVGSGSQTPGSKKDKPNYNCLLCPKSYRKRKSLLDHYKMHPGYCHDCGQPNGNTLEEIIHHNRTMHVKEFPFVCETCGESYSRKQQFHAHVESHNKKEIKTFPCGECGQKFPQKKLQQHFEETGHKADGAICEVCGEEFTSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEVKRPYVCDLCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHSCNYCDQTFKWKTHLVRHKQAMHGNEPVPPKKGKQRFPKANEEEMASLPDMPGPPPVKASKKSVANKAKAQAVAVASVTSQQQLKGAAATPTPPPPVSTTPGCLQQDQFNAAMVSSNSSQSSTASTSQHSVSTSESQQNSMYSQSFNAEKLQAAGQQQPQQPNPLHQQHPTPPPTQQQQQQQQPRVGSAEMHLQRMNSFTQEGHLHGPQAQQQQPMHPHLLPPPAPHGSVYDRTGVGVGVGVGYSMLGDDPKGVLPPMMGMMQQMPPHGQQPDLIYYPVKND
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -