Basic Information

Insect: Drosophila ercepeae
Gene Symbol: BCL11A
Assembly: GCA_018150545.1
Location: JAECWL010000174.1:10706060-10718409[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.016 1.1 9.7 2.4 1 23 292 315 292 315 0.95

2 6 1.6e-06 0.00011 22.3 1.0 1 23 450 472 450 472 0.97

3 6 0.0073 0.51 10.7 4.7 1 23 478 500 478 500 0.99

4 6 6.8e-07 4.7e-05 23.4 3.2 2 23 760 781 759 781 0.97

5 6 8.9e-06 0.00062 19.9 3.3 1 23 787 809 787 809 0.99

6 6 1.6e-05 0.0011 19.0 0.4 1 22 817 838 817 838 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.016	1.1	9.7	2.4	1	23	292	315	292	315	0.95
2	6	1.6e-06	0.00011	22.3	1.0	1	23	450	472	450	472	0.97
3	6	0.0073	0.51	10.7	4.7	1	23	478	500	478	500	0.99
4	6	6.8e-07	4.7e-05	23.4	3.2	2	23	760	781	759	781	0.97
5	6	8.9e-06	0.00062	19.9	3.3	1	23	787	809	787	809	0.99
6	6	1.6e-05	0.0011	19.0	0.4	1	22	817	838	817	838	0.97

Sequence Information

Coding Sequence: ATGAGTATTTTTTTTTTTCAATCACCCATCAAAATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGATCGCTGAGCCATTCCGACTCGACGGAGAACGATGCCGTGGCCACGCAGGACATCCTCACATGCGGCGCCTGCCAGAAGGCGTTCGCCCTCTCCGACATCGTCAAGTTCATCCAGCACAAGGTCCTGCAGTGCAACAAGGAGAACTACGGCCAGTGCGCCACCCAGAATCCCCAGATGGATCGCGATGCCGAGGAGGGACGTCCTCTGAGCCTGGTCAATCGCCGGCCCTCGATTTCGGCCCCCATCTCGGGCCGCAAGTCCTCCTCGTCCTCGTCGTCCTCCTCCACATCCTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCAAGGATACACACACCACCCCCGAGTCCGGCGGATTTGCTGGCGGACGGAGCCAGCAGCACGCCCAAGAGGCTGGTAGATGAAAACGACAACACCACGCCCAAGGACATTGAGACAGCTGCCACCACCCTGGACAAGGACTCAGCCGCTCCCGGCAGTCCTCTGGCCAGCCAAAAGCCACGCAGATCCTCCAGCGCCGACAGCAGTTGCGAGCTCGACCAGGATCAGGACTCCCAGCAGCCTGCCAAGGTCAAGGAGGAGCCCTTCGAGGACGAAACCACCGCCCCACAGAACCACGACGAAGAGGACGACGAAGAGGAGGAGGAACAGGAGCAGTCGCTGGCAAAGAGGCCAAAAATGGAACTGGTCGATGCCGAGGCCAACACAGTGCACACAGAACCCAGCAACTACACTTGCTCCACGTGCAAGACCCGCTACACCTCCGCCTGGCGTCTCATCCAGCACGTCCAGCACTCCCACGGCGTCAAGATTTACGTGGAGAGCCCGGGAGCGATGGGGGGAGCCACCCTGACGGTGGCCACTCCCGCCGCCCTCAACAACAGTGCTCTGGCCCTGGCTGCGGCAGCGGCGGCTGCTGCCTCAGTGACCTCCGGCTCCGGCTCCGGTTCCGGCTCGAGCTCCGTTTCCGTTTCCGGCAATGCCAGCTCTCCGCCACCGACGACGATCAGCCCCAGTCCGGTGGGCAAGCGGAGCAGCCCGCTGGCCGCCAATCTACCCCACTCCCTGACTCCGCCGGAGAAAATGAGCTCCGAGAACTCTGCCGAGAACGGCAACCTGGGACTCATCCTGGCCAGCACTCCCCGATCCGCCAGCACTCCGCCCTCGAAGACGGGAGAGATCAGCAGCTCGCAGGACAACTGCTTCGCCTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAACCTGATCATCCACCAGAGGACCCACACCGGGGAGAAGCCCTACAAGTGTACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGAGTGCATCGCTCCCCGCCCGCGGAGGACAACCAGGACGAGGGCAGCAATGCCGACTCGCTGGAGACCAACGAGGCTGACCACGACGAGGATCCCAACCCGGAGGACTCCGAGGAGGAGCTGAACGACGCCGATGGCGAAGTAGACCTCGATGGCGAGGAGGAGGACGACCTGGACGAGATGGAGGAGTGCGAGGACATGGACTACAAGGCGGAGGATCTCTCCGTGAGCAACCGCCTGGATGGCAAGAGCCAGAGTCCCAAGACCACCAGTTCCGGCGCCACCTCCCTCGTCGGCGAGCTGATGGACAAGTTCGGCCTGTCCAACATTGCCCAGTACAGCGAGGCCTACAAGCAGGCGCTCCAGGAGTCCGGTCGCAAGGAGGCCGCGGCAGCAGCCGCCGCCGCAGCAGCCGCAGCCGTGGACAACAACAACCGAGGTCCTGGCTCCGGTGGCGGTGGAGCCGGAGGACCCGACAAGCTCAACGGCCTGCCGGTGGCTGCCCTGCGTCTGCGCGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCAGCCGCAGGACGGCGGCGCCCCCACCCAGGTGCCCCTCTTCAACCCCTTCCCCAATCCCTTCGAGCTGAGCAAGCGGATCAAGATGGACGGCGGCGACTGGTGGGGCATGTCCCAGGCCCTGCACCGCAACGAGGCCCTCTTCGAGAACCTGAAGCTGAAGCCCCTGGGCCTCGGCGGAGCCAACTCCCTGATCCAAGGACCTCTGCTCAAGAAGGAGAGCCGCCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTCACCGTTCACCGGCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTGACCAGGCACATGAAGACCCACGGCAGGACCGGCAAGGACGTCTACCGCTGCCGCTTCTGCGACATGCCCTTCAGCGTCCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTGGTGAACCAGGGCAAGGCCGCCGCGGCCGCCAATGCCGTGGCAGCTGCCCAAGCGGCCCAGGCGGCCGCCCAGCAACTCCAGGCGGCAGCGGCGGTCCAGGCCGCCCAGCAGCAGCAGCAGGCCCAGGGTCAGGTACCCCAGCCGGGACAGGGTCAGGGCCAGGGCCAGCAACTGTCGCCCCTCGGGGTCGTGGGCTATGCCCCCGCCTTTGTCGGCGGACACAACATCTCACTGCCGGGCAGTGTGAGTGGCGACAACGATTCCAATGCCTCTTCCAGCCTCACCGGAGTCCATCCCATTTCCCTCAAGGAGGAGGCATGA
Protein Sequence: MSIFFFQSPIKMYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSSSSSSSSSTSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDIETAATTLDKDSAAPGSPLASQKPRRSSSADSSCELDQDQDSQQPAKVKEEPFEDETTAPQNHDEEDDEEEEEQEQSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGAMGGATLTVATPAALNNSALALAAAAAAAASVTSGSGSGSGSSSVSVSGNASSPPPTTISPSPVGKRSSPLAANLPHSLTPPEKMSSENSAENGNLGLILASTPRSASTPPSKTGEISSSQDNCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPPAEDNQDEGSNADSLETNEADHDEDPNPEDSEEELNDADGEVDLDGEEEDDLDEMEECEDMDYKAEDLSVSNRLDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAAVDNNNRGPGSGGGGAGGPDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPTQVPLFNPFPNPFELSKRIKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQQLQAAAAVQAAQQQQQAQGQVPQPGQGQGQGQQLSPLGVVGYAPAFVGGHNISLPGSVSGDNDSNASSSLTGVHPISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00566311; iTF_00539177; iTF_00488239; iTF_00476151; iTF_00580191;
90% Identity: iTF_00539177;
80% Identity: -