Basic Information

Insect: Drosophila ercepeae
Gene Symbol: -
Assembly: GCA_018150545.1
Location: JAECWL010000189.1:13409852-13413188[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.021 1.4 9.3 0.5 2 23 38 59 37 59 0.96

2 13 0.00042 0.029 14.6 1.7 1 23 65 88 65 88 0.95

3 13 0.0063 0.44 10.9 1.3 1 19 102 120 102 123 0.93

4 13 0.094 6.5 7.2 1.3 3 22 140 159 138 159 0.90

5 13 0.29 20 5.7 2.0 2 23 409 431 408 431 0.94

6 13 0.012 0.82 10.1 0.3 1 23 456 478 456 478 0.97

7 13 0.0047 0.33 11.3 1.6 1 23 486 510 486 510 0.95

8 13 0.1 7.3 7.1 2.4 2 23 515 537 514 537 0.95

9 13 0.00026 0.018 15.2 0.2 2 21 550 569 549 570 0.93

10 13 0.008 0.55 10.6 0.4 3 23 580 600 578 600 0.97

11 13 8e-07 5.6e-05 23.2 2.8 1 23 606 629 606 629 0.98

12 13 3.2e-05 0.0022 18.1 1.4 1 23 635 657 635 657 0.98

13 13 0.0003 0.021 15.1 2.9 1 23 663 685 663 685 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.021	1.4	9.3	0.5	2	23	38	59	37	59	0.96
2	13	0.00042	0.029	14.6	1.7	1	23	65	88	65	88	0.95
3	13	0.0063	0.44	10.9	1.3	1	19	102	120	102	123	0.93
4	13	0.094	6.5	7.2	1.3	3	22	140	159	138	159	0.90
5	13	0.29	20	5.7	2.0	2	23	409	431	408	431	0.94
6	13	0.012	0.82	10.1	0.3	1	23	456	478	456	478	0.97
7	13	0.0047	0.33	11.3	1.6	1	23	486	510	486	510	0.95
8	13	0.1	7.3	7.1	2.4	2	23	515	537	514	537	0.95
9	13	0.00026	0.018	15.2	0.2	2	21	550	569	549	570	0.93
10	13	0.008	0.55	10.6	0.4	3	23	580	600	578	600	0.97
11	13	8e-07	5.6e-05	23.2	2.8	1	23	606	629	606	629	0.98
12	13	3.2e-05	0.0022	18.1	1.4	1	23	635	657	635	657	0.98
13	13	0.0003	0.021	15.1	2.9	1	23	663	685	663	685	0.95

Sequence Information

Coding Sequence: ATGGCCTCAGAGTCGATGGCCCCCAGCAGCAGCAGCAGCGCCGCCGCCGCAGCAGCCGCTGCTGCCACCAAGCTCCTGGTGGAGATATCCACGGACGGAGTACCGAAGCTGCACTGCCCGGTGTGTAACAAGGCCCTGTTCTCGCTGGCCGGTTATGTGAAGCACGTCAAGAAGCACCAGCCGCCGGGAGGGTTTGAATGCCGCCAGTGCGACGCCCGGTACTGCAGCCAGGACGAACTGACCCAGCATCTGAAGGATGAGCATCCGGATAGTGGCTCGGGCGACAGCCTGGAGCGCAAGCCATATGTCTGCGAGAAGTGCGGAGCAGAGTACAAGTACCAGGAGGCCTATCGACGCCACTGCCGAACCAAGTGTGGCGAAGAGAAGCTATCCAAGGAGGAATCGCGACCGGTGGAGTGCCAGTGCTGCTCTACTCGCTTTTCCAGCGATGAAAACCTGGAAAACCACCGACGCAGTCGTCCCGACACTTGCGGCCAGCCGGAGTACGATCCACTGGGCGGCTCAGAGCAAGAAATGAAGCAAAAGTATCGCAAGAAATTGAAACGAGACGATTCTGATGAGGAAACCACCTCCGAGGAATCGGAGGACAGCGACGATGACATTCCCCTGGCCAGTCGGCTGAAGACGAAGCTAAAGCAGGAGAGCCAGAGCTCTGATTCGGGCGACGAGTGCCCCGAGTTCCAGGGCAACAATAGTGAAGACGAGGCGTTCCCATTGCCGCCACCGGCCATGGTCAAGGTGGAGGCCTTTGACGAGGAGGACTTTGAGTACCAGGACGCCAGCATGTATGTGAAGACCGAGAGCACGGACATCTTCAGCAATGAGAAGGACAAGTTGTTGGATGTCCTGCTGAACGAGGGCGACGGCCTAAAGCCGTTCGAGAGTCTGAAGGTGGAGCAGGGCGCCGGCATCCTGGATGAGATTGCGGCCGTGCCGCTTGTAGAGGTGGCCGAGGAGGATGTCCTGTCGCTGCGTGGGGGTCGCTCCGATAAGCCTAGCATGAAGAGGCGAGGCAGACCGCCCAAGGGAGAAAGGCGAGAGCCACCATCGGAACCAGTTGTCAAGCGAAAGTATCGCAAGCGAAACGCTCCAAGATCGCCTTCACCGGATGACTCCTCGGGAGGACCCAAGCGAATGGCCAAGATCAGCAAGAAGGAACTAAAAGAACGTCTTAAAATGATCAACAAGATGGAGAAGTCCTGGAAGTGCCCGCACTGCGTCAAGATCTACCACATTCGCAAGCCGTACGAGAAACATTTGCGCGACGATCACAAGCTAACCGAACAAGAGATGCGCGAAATCTTCAAGGACGTGGACGTGCATGCCAAGCTGGACGAGGAGGTCTTCAAGTGTCCCATCTGCAGCAAGATCTACCTGGTCGAGAAGCGCCTGGTCACCCACATGAAGGTTCACGGCGAGGATGGCAAGCTCACGTTCAAGTGCCCCTGCTACTGTAATCTATTCTTCGCCACCAAGGAGCAGGCCACGGAGCATGCCCGCGCCCAACACAAAGAGCTGCTCTACTGCGAGAAGTGCGACAAGTACATGACCGGGCACGACAGTCTCAAGAACCACGAGCGCAACTTCCACTCTAAGCGGGAGCCACGCAGTCAGATCCGCAACCTTATCTGCGACAAGTGTGGCAAGAAGTTCACCGGCCGCACCTCGCTCTCCGATCATGTGCGTTCCGACTGCGGTCGCTTGCCCCTTTACGGCTGCTCCGTTTGCGGCAAGCATCTTTCCACAGCCGGCATTCTCAAAACACACATGCTCCTCCACAAGGCAGACACTCCATACCAGTGCGACAAGTGCGGCAAGACGTTCAAGGTGAAGGCACAGTACAAGTCGCACTTGAAGACGCGACACACGGACTACAAGCCCTACAAGTGCCACCTGTGCCCCAAGGAGTATCCGTACAGGGAGAGCTTGCTCACCCACATGACCGTACACACTGGGATTAAGCGCTTCCTGTGCAATAACTGCGGCAAGCGGTTCACCTGCATCTCCAACCTGCAGGCCCATCGCAAGGTGCATGCCGACACCTGCGGCCAGTTGCCGCTCAACGCCAAGGCAACGCAATATATGGGCGTGCAGCGCGGCAAGCTGCTGATGGGAGCCAAGCCGGAGGCCGGAATGGCCTACGATGAGACAAAGACCCTGATCGCTGAGGAGGTCATCGAGAAGGACATGCCCATGGCCCAGGAGCTCAACTTCCCCTCCGACGGCTCGGCCCCGCTAGCCACCGTGCCCCTCAACTACGCCTCCACGCACCTGGTGCCCCATATCGTACTCCAAACCATGCAGGCCGAGGCACGGCGGCTGGAGTAA
Protein Sequence: MASESMAPSSSSSAAAAAAAAATKLLVEISTDGVPKLHCPVCNKALFSLAGYVKHVKKHQPPGGFECRQCDARYCSQDELTQHLKDEHPDSGSGDSLERKPYVCEKCGAEYKYQEAYRRHCRTKCGEEKLSKEESRPVECQCCSTRFSSDENLENHRRSRPDTCGQPEYDPLGGSEQEMKQKYRKKLKRDDSDEETTSEESEDSDDDIPLASRLKTKLKQESQSSDSGDECPEFQGNNSEDEAFPLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLSLRGGRSDKPSMKRRGRPPKGERREPPSEPVVKRKYRKRNAPRSPSPDDSSGGPKRMAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLTEQEMREIFKDVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFHSKREPRSQIRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMAYDETKTLIAEEVIEKDMPMAQELNFPSDGSAPLATVPLNYASTHLVPHIVLQTMQAEARRLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615081;
90% Identity: iTF_00546135;
80% Identity: -