Basic Information

Insect: Drosophila ercepeae
Gene Symbol: Cf2
Assembly: GCA_018150545.1
Location: JAECWL010000189.1:9495943-9499199[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.045 3.2 8.2 5.8 1 23 81 104 81 104 0.95

2 8 0.0078 0.54 10.6 0.9 1 23 139 162 139 162 0.94

3 8 0.61 42 4.7 0.6 1 12 189 200 189 203 0.88

4 8 2e-07 1.4e-05 25.1 0.8 1 23 374 396 374 396 0.98

5 8 3.8e-08 2.6e-06 27.3 2.7 1 23 409 431 409 431 0.99

6 8 3.4e-07 2.4e-05 24.3 1.1 1 23 437 459 437 459 0.98

7 8 3.8e-07 2.7e-05 24.2 3.5 1 23 465 487 465 487 0.98

8 8 1.2e-07 8.5e-06 25.7 1.4 1 23 493 516 493 516 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.045	3.2	8.2	5.8	1	23	81	104	81	104	0.95
2	8	0.0078	0.54	10.6	0.9	1	23	139	162	139	162	0.94
3	8	0.61	42	4.7	0.6	1	12	189	200	189	203	0.88
4	8	2e-07	1.4e-05	25.1	0.8	1	23	374	396	374	396	0.98
5	8	3.8e-08	2.6e-06	27.3	2.7	1	23	409	431	409	431	0.99
6	8	3.4e-07	2.4e-05	24.3	1.1	1	23	437	459	437	459	0.98
7	8	3.8e-07	2.7e-05	24.2	3.5	1	23	465	487	465	487	0.98
8	8	1.2e-07	8.5e-06	25.7	1.4	1	23	493	516	493	516	0.96

Sequence Information

Coding Sequence: ATGATAAAGTCTACCACGAACCCACAGGAACAGCGTTTGCCACGCCCCGAGGATCAGGATCTGGATCATCATCAGCAGCAGCAGCAGCCACAGTCGCCACCCCCTTCCACCACCACTTCCACATCCTCCCCCGCAGCTGCCACACCCACCATTCTCCAAGCAACCGCCGCCGCCATGGACACACTGAAAACCGCCTTTCTGCCCAATCTCAGCATGGACCCCAACGTACACGTGACCCCGCACTACTGTCCCATGTGCCACCAGCAGTTCGAGCGGGCCCAGCACGCCGCGGAACACATGCAGCTGTGCCACGGGATAACGCTGAACGCCCAAGGAGCCATCACCACCCTAGAGGCTGCGCAGCAACACCAGCAACAACAACAGCAACAGCAACAACAACTAAAGCCTCCCACTCATGCGTGCTTCAACTGTGATGAGAAATTCGGCAACGCCGTAGACCTGGACGAGCACCATCGGCTGGTCCACCAGACGTCCGCCTTCCTGGCCCGCTGCCTCGTGTGTAGCATCTACGGCGTGCATTCGGCCACTCCCCAGCCCAATGAATACAAGTGCACGCAGTGCGGATCCGTGTGCACCACCGCGATGCTGGCTGCCGGACAGCAGAGCTTTATGGAGCAGCAGGAGGCGTCGGTGACGCCGGACGAGCAGCTGCCGGCGATGGCGCCGCGTGATATGAGACTGACGCCGGAGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAGGTGGCGCTCAAGGTGCCTCCGCTCACCGTCAAGCTGAACAAGAACGCCAATGGTGCCGCCATCGTGGCCCATCCACAGGTGATCATTAAAGAGGAACCACTCAGTCTGAGCGACAGTGGGGATGTGGTGAACGCCGTCCCCGTCTATGCCATACAAGCGAATCCTGGCGTCCCGGCGCCAACTACCTCCAGCGTTCTCGTCGGCACGCAAACGGTGCCCGCCGATCTGGCGCACAAGATCCGGCACAAATGTCCGGACTGCCCCAAGACCTTCAAGACGCCCGGCACCCTGGCCATGCACCGAAAGATTCACACAGGCGAAGCAGACGCCACGCCCAAAGAACGCCCCTACACGTGCTCCTACTGCGGCAAGTCCTTCACTCAATCGAATACACTAAAACAGCACACTCGCATACATACAGGTGAGAAACCATTTAGATGTGGCTATTGTGGCAGGGCGTTCACTGTTAAGGATTACCTGAACAAACATTTAACGACTCACACGGGAGAAAAACCGTTTCATTGTGGATACTGTGAGAAGTCCTTCAGCGTGAAGGACTACCTAACCAAGCACATACGGACACACACCGGCGAGAAGCCGTACACCTGTCCGTATTGCGATAAGCGCTTCACCCAGCGCAGTGCACTCACCGTGCACACGACCAAGCTGCATCCGCTCTAG
Protein Sequence: MIKSTTNPQEQRLPRPEDQDLDHHQQQQQPQSPPPSTTTSTSSPAAATPTILQATAAAMDTLKTAFLPNLSMDPNVHVTPHYCPMCHQQFERAQHAAEHMQLCHGITLNAQGAITTLEAAQQHQQQQQQQQQQLKPPTHACFNCDEKFGNAVDLDEHHRLVHQTSAFLARCLVCSIYGVHSATPQPNEYKCTQCGSVCTTAMLAAGQQSFMEQQEASVTPDEQLPAMAPRDMRLTPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVALKVPPLTVKLNKNANGAAIVAHPQVIIKEEPLSLSDSGDVVNAVPVYAIQANPGVPAPTTSSVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605000;
90% Identity: iTF_00580119;
80% Identity: -