Basic Information

Insect: Drosophila ercepeae
Gene Symbol: -
Assembly: GCA_018150545.1
Location: JAECWL010000192.1:1463302-1467915[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.0039 0.27 11.6 1.3 1 23 205 227 205 227 0.97

2 22 0.12 8.6 6.8 0.7 1 23 233 255 233 255 0.97

3 22 2.8 2e+02 2.6 2.9 2 23 287 308 286 308 0.94

4 22 2.7e-05 0.0019 18.4 0.4 1 23 381 404 381 404 0.94

5 22 0.3 21 5.6 1.4 1 23 445 467 445 467 0.97

6 22 2.4 1.7e+02 2.8 0.1 2 23 476 497 475 497 0.92

7 22 1.9 1.3e+02 3.1 1.9 1 23 575 598 575 598 0.92

8 22 0.39 27 5.3 0.2 1 22 607 628 607 628 0.95

9 22 0.00034 0.024 14.9 2.4 2 23 684 705 683 705 0.97

10 22 0.15 11 6.5 2.6 1 23 874 897 874 897 0.94

11 22 0.23 16 6.0 0.4 1 21 904 924 904 925 0.92

12 22 0.006 0.42 11.0 1.2 1 23 934 957 934 957 0.97

13 22 0.0016 0.11 12.8 2.1 2 19 978 995 977 999 0.93

14 22 0.00016 0.011 15.9 0.5 1 23 1006 1028 1006 1028 0.98

15 22 0.0026 0.18 12.1 2.9 1 23 1121 1144 1121 1144 0.96

16 22 0.0069 0.48 10.8 0.4 1 23 1181 1204 1181 1204 0.96

17 22 0.00095 0.066 13.5 1.3 1 23 1231 1254 1231 1254 0.97

18 22 4.7e-06 0.00033 20.7 0.2 2 23 1277 1298 1276 1298 0.95

19 22 0.00013 0.0092 16.2 2.9 1 23 1304 1326 1304 1326 0.99

20 22 1.9e-06 0.00013 22.0 2.0 1 23 1332 1354 1332 1354 0.97

21 22 1.6e-07 1.1e-05 25.3 2.4 1 23 1360 1382 1360 1382 0.99

22 22 0.041 2.8 8.4 0.1 1 21 1388 1408 1388 1412 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.0039	0.27	11.6	1.3	1	23	205	227	205	227	0.97
2	22	0.12	8.6	6.8	0.7	1	23	233	255	233	255	0.97
3	22	2.8	2e+02	2.6	2.9	2	23	287	308	286	308	0.94
4	22	2.7e-05	0.0019	18.4	0.4	1	23	381	404	381	404	0.94
5	22	0.3	21	5.6	1.4	1	23	445	467	445	467	0.97
6	22	2.4	1.7e+02	2.8	0.1	2	23	476	497	475	497	0.92
7	22	1.9	1.3e+02	3.1	1.9	1	23	575	598	575	598	0.92
8	22	0.39	27	5.3	0.2	1	22	607	628	607	628	0.95
9	22	0.00034	0.024	14.9	2.4	2	23	684	705	683	705	0.97
10	22	0.15	11	6.5	2.6	1	23	874	897	874	897	0.94
11	22	0.23	16	6.0	0.4	1	21	904	924	904	925	0.92
12	22	0.006	0.42	11.0	1.2	1	23	934	957	934	957	0.97
13	22	0.0016	0.11	12.8	2.1	2	19	978	995	977	999	0.93
14	22	0.00016	0.011	15.9	0.5	1	23	1006	1028	1006	1028	0.98
15	22	0.0026	0.18	12.1	2.9	1	23	1121	1144	1121	1144	0.96
16	22	0.0069	0.48	10.8	0.4	1	23	1181	1204	1181	1204	0.96
17	22	0.00095	0.066	13.5	1.3	1	23	1231	1254	1231	1254	0.97
18	22	4.7e-06	0.00033	20.7	0.2	2	23	1277	1298	1276	1298	0.95
19	22	0.00013	0.0092	16.2	2.9	1	23	1304	1326	1304	1326	0.99
20	22	1.9e-06	0.00013	22.0	2.0	1	23	1332	1354	1332	1354	0.97
21	22	1.6e-07	1.1e-05	25.3	2.4	1	23	1360	1382	1360	1382	0.99
22	22	0.041	2.8	8.4	0.1	1	21	1388	1408	1388	1412	0.91

Sequence Information

Coding Sequence: ATGCTACCACCAAACACGTGCCGAACTTGCGCGGTGCAAAATCCCGACTTGCAGCCGCTTTCTGCTTGCGTGGAAAAAGAGGGCAATAAGAGTTTCTACGAGGTGCTTCAAGAGTTAACGCAAATCGACCCCCTCCAGGAGAGCTTGGACGCCAGCCTACCTCAGCATTTGTGCACCGATTGCTTAAAGAGATTGAAGAATGCCTACGCTTTTGTGCAGCAGGCCAGAAAAGTTAACGGAGAACTCTTGGTGCAACTGAGGCAATGCCTTGATGAGACGCCCATAGACATACCCCAGGAACAGCAAATAAAAGCTGAAATTGATGCTGATCCAGAAGAAGAAAATGCGGTAGAGGAATCCTTTGCAAGTCCATCTGAAGAGGGCAAATGGAACGCGGAAAGTGACAGTGATAACAGGGTAAATCCTGGGAGTGCCAGCAAAGTGGAGGAAGTCGATGAAAAGCCTTATCAACTAAGAAGTGCCCGGAAAGTCAAGCAGCCAGCAGATAGTGACGATGAGGAAGCCAACCTCAGTGAACTATCGCCGTTGAAACGCAGGCGTGGGCGACCTCCGGGTAAGGCCAAGAGCCAATCGATGACTTCCGATGGGCGATATGCATGTCGAGTATGCGACAAAAGTTTCTCCTGGTACCGCGACATGCAACGCCATTCACGGTCTCATTTTGATAATAACAGCTATGTGTGCAGAGCATGTGGTAAAGGATTTCTACGCAAGGACAATTATGTATTTCATCTTCGCAGTCATGCCAAGAAGTTGGCCAAGCAGGAGTCCCTAAAGCTAGGCAGCGAATGGGTCTTCGCTGAGCGTTTATACTCCTCCGGGAAGCTAAAAAGAATTGAATGCAAGCTATGCAATCATAAGTACGAAAGAATCGAGGATCTCAGATGTCATTTGGACTCTCACATAAGCCTAGAAAGTTTGAACGCCTTAAAGCTGGATAGCGACGTGGTGCGAGAGCATTATAATATACAATCTGGCGACATGGACAGAATAAAGAATATGATTGTGTCAGATGTATCTCAGGGAATTTTTGAAAAGTTTACATCGATAGTGAATATGTATGGATATGAGCTGAATATCAATGATTCCGATGAGGAGTCTCCTTCAGTAAATGAGAAATACGTTTGCGAGATGTGTAACGAGGCATTCGCTCGCCAACATCAGCTTGTTAGGCACACGCTGGAGGAACACGCGCAGGCATCGTCTGATGAGCTTCCTTGGCAACGTTGCAGTTTTTGCAAAATTGGATTTCTTTCCTCGGCTGTCTATAATCAGCATTTGCACCACCAATGCCACAACAAGCTAAAGAAATATACCTGTCGAAAGTGTCCTGGGAAATTCATGTGGTTGGACAATCTGGAAAGACACGCTTGCTCTCATCGGACTAACCGAGAACGTCAAATTACCTGTACTTTGTGCAATGCTCAATTGCCTAGTTTAGTGAAGCTACGTATCCACCTGGTTGACCACCAAAAAGATTTAAAAAGCTTTAACCCCGATCTCCAGTCTATTTTCTTTCAATCCTTCTACCCCAATGGCTTGGAATGCACTTCCTCAGAACTAAGTGCTCGTATTATGGAAGATTTTGAGGTCCAAGACTTTGAACGCTATTACAATGCTGCTACCTCCAGTGGACGCGAGTTGGATATCTTCGATTCCGAAACTGAGGAATCGCAAGCAGAAGATGACGGTGCACCACAGCATACTTGTATTCTTTGCGGAAAAATGTCAAAAAGGCTTTTGGTCCTACTTCAGCACCAGAAAAGTTTTCATTCAGAGGAATTAAGTGCTCTGCCCTTTGTTTGTGAAGCCTGTGATGAAGGATTTGTTTGTGAAGCATTGCTTCAAAAGCATCGAAGACGCTGCAGCGCAAAAGGGAGCTCAAGGTTCCATTGCCTTAATTGCAATCTACATTTTTTGTGGAAGAGCAACTACGAGAACCACATAAAAGCACACCACGACCAGGAGGAGAGCTCGGAGACGGCAGAAAGTCGTTCGCCCAAACTATGCTCATCTGCAACCAAGCTGCAGTGTGATGAGTGTGATAAGACTTTTATTTGGCACAAGGACCTTACCCGCCATAAGCGCATGCATCAAACAGAAGTAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCTTAAGTCGCATATGCGGGTGCATTCGACAATCGAGCAACGATCGGATCAAACGGGAAAGCAGTCAGTAAATGGTGGCAATAGTGCCCTTTCCATTTTGGACCACCTCTGTCGACCAAATGGCTGTAAACAAATCCAATGCATGATCTGCCTCTCCCGTCACACAAAAATTTCTGACCTTCGAACACACCTTACGACGCACAAGTATTTCGTGACTTTCTCCGATGATAGAGACATTGCTAGCGCATCAAAAGCTCTTTATCCAGAACTATCTGCAGCTTTGGACAGAACTAAACTGGCAGAGAGAATAATGGCTGATGTGGGGAAAGAATGCGACCTAGACAGATTCACTTTCATCGCGAACGAAACAGGATTGGAATTGACTCTAGATAGTAGTGAAACGGATACAGAGTCGGATCAAGAAGAGGAACATTCGACTCACACCTATAACTGTCACATCTGTGCAATACAGGTGAAGCGAAAATACTTATTATATGCGCACCACTTAGAGAAGCATACGAGTGAAGAGGGTCCCTTTGTTTGCTCCCAATGCCAGACTGGGTTTCTCGATAAGGCCCTTCTAGAACACCACTCCCAAACGCTTTGCCGCAATTCCCAGAAACGCTTCCAGTGCCGCAAGTGTCCGCTACGATTTCGCTGGCGCGAAAACCTGAAATTACACACCAATGTGAGTCACCAGCAGTTGGAGACTGTAGATGAAGGTGAAGCTGTTCCAACCCAGGGCGAGGGCGATCTGCACTGCAAAGAATGCCAGCGAAGCTTCAAAATGCAGAAGGATCTTACGCGACACAGTTGGATGCACGCCAAGGAGTCTAATATATATCGGTGCCGGTGGTGTGCCCGCCGCTTCTACCGTTGGGCCAACCTCCTTCAGCATATTGTACGCCATGGGATCAGGGCCAATCAATTGCCCTATGCGGAGGCTCTTCTTGACTCATACGGACATCCCGGAGGCAACAAGGTCATCGAATGTCGCGTGTGCTGCGTAAGATTTCCTAAGATTGCTGACTTGCGTTTGCATCTTGAAAGCAGTCCGGTGGGCAGTCACCACGAGCTTTTGTCGCTCCAGAACTACTCTATAACCAATCAGATGGGCTATGAGCTAACTCTGGAGGATTCTGAGACGGATGAGGAGGCATGTAAACCACCAGAAGCTCCGGCCTATTACACATGCAGCATGTGCCAATTGCGGTGCGTGCGAAAGTTCGAGTTGCAGCAGCATCAGCAGGCCATGCACCGAATTGAAAAGATTCCCGATGGTTGCGATCACTGCATCTTCAAGAGTGTGTGCCCAGAACTGATTGCCCATCATGTAAGGACGCAGTGTGGCAATTTGGAAAAACACTTCATCTGTACGCGTTGCGGATACAAGTTTATGTGGGAATCCAATTTGTTGCTCCACATGCAGATTCAGCACAACAAAAAGGAGAATGCAGAGCAGGACTCTGCCATTCTGGAATCTCCCGATGAGCCTAACAAAGCTACCTGCCAAATATTTCAGTGTGCACTCTGCCCGCGGAAGTACAACCGTAAAGATCGACTGTCAGCGCACGTTAAGAAGTTTCACGGACCCAATATAGAGAAGACACCCAACCGGCCACCCATCGCAGAGCCCAAGGAGCCGAAACGATTCCTCTGCGCCTTTTGTGGCAAAGCCGTAAGCTCTTCCTCAAACTTAATCATCCATATGCGGCGTCATACCGGTGAGAAGCCCTTCAAGTGCGACTACTGCGAAATGGCTTTTCCCCGATCCTCGGATCTCCAGTGCCATCGAAGGACGCACACAGGCGAAAAACCGCACGTGTGCACAGTGTGTCAGAAGGGATTCGCCCGATCCTACAAGCTGCAGCAGCACATGCGTATCCACAGCGGCGAGAGACCTTACAAATGCACCTACTGCGAGAAGAGCTTTACCCAATCCAACGACCTGACCCTTCACATCCGACGGCACACGGGTGAACGTCCGTATCAGTGCGGCGTCTGCGGTGATCGTTTCATCCAGGGCACCGCTTTAAAAAACCACCGTTTACAACAGGGCCACCACGAAGATACCGCCACTGTCCAGAGTACCGCACCAGGAGAAAAAGGCGTACAGACATAG
Protein Sequence: MLPPNTCRTCAVQNPDLQPLSACVEKEGNKSFYEVLQELTQIDPLQESLDASLPQHLCTDCLKRLKNAYAFVQQARKVNGELLVQLRQCLDETPIDIPQEQQIKAEIDADPEEENAVEESFASPSEEGKWNAESDSDNRVNPGSASKVEEVDEKPYQLRSARKVKQPADSDDEEANLSELSPLKRRRGRPPGKAKSQSMTSDGRYACRVCDKSFSWYRDMQRHSRSHFDNNSYVCRACGKGFLRKDNYVFHLRSHAKKLAKQESLKLGSEWVFAERLYSSGKLKRIECKLCNHKYERIEDLRCHLDSHISLESLNALKLDSDVVREHYNIQSGDMDRIKNMIVSDVSQGIFEKFTSIVNMYGYELNINDSDEESPSVNEKYVCEMCNEAFARQHQLVRHTLEEHAQASSDELPWQRCSFCKIGFLSSAVYNQHLHHQCHNKLKKYTCRKCPGKFMWLDNLERHACSHRTNRERQITCTLCNAQLPSLVKLRIHLVDHQKDLKSFNPDLQSIFFQSFYPNGLECTSSELSARIMEDFEVQDFERYYNAATSSGRELDIFDSETEESQAEDDGAPQHTCILCGKMSKRLLVLLQHQKSFHSEELSALPFVCEACDEGFVCEALLQKHRRRCSAKGSSRFHCLNCNLHFLWKSNYENHIKAHHDQEESSETAESRSPKLCSSATKLQCDECDKTFIWHKDLTRHKRMHQTEVXXXXXXXXXXXXXXXXLKSHMRVHSTIEQRSDQTGKQSVNGGNSALSILDHLCRPNGCKQIQCMICLSRHTKISDLRTHLTTHKYFVTFSDDRDIASASKALYPELSAALDRTKLAERIMADVGKECDLDRFTFIANETGLELTLDSSETDTESDQEEEHSTHTYNCHICAIQVKRKYLLYAHHLEKHTSEEGPFVCSQCQTGFLDKALLEHHSQTLCRNSQKRFQCRKCPLRFRWRENLKLHTNVSHQQLETVDEGEAVPTQGEGDLHCKECQRSFKMQKDLTRHSWMHAKESNIYRCRWCARRFYRWANLLQHIVRHGIRANQLPYAEALLDSYGHPGGNKVIECRVCCVRFPKIADLRLHLESSPVGSHHELLSLQNYSITNQMGYELTLEDSETDEEACKPPEAPAYYTCSMCQLRCVRKFELQQHQQAMHRIEKIPDGCDHCIFKSVCPELIAHHVRTQCGNLEKHFICTRCGYKFMWESNLLLHMQIQHNKKENAEQDSAILESPDEPNKATCQIFQCALCPRKYNRKDRLSAHVKKFHGPNIEKTPNRPPIAEPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGEKPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGDRFIQGTALKNHRLQQGHHEDTATVQSTAPGEKGVQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550383;
90% Identity: iTF_00615041; iTF_00546098;
80% Identity: -