Basic Information

Insect: Drosophila ercepeae
Gene Symbol: -
Assembly: GCA_018150545.1
Location: JAECWL010000164.1:18315082-18316844[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00044 0.031 14.6 0.2 3 23 230 250 228 250 0.98

2 12 9.4e-06 0.00065 19.8 1.2 3 23 262 282 260 282 0.96

3 12 2.4e-06 0.00017 21.7 0.8 1 23 288 310 288 310 0.98

4 12 1.7e-06 0.00012 22.1 1.8 1 23 316 338 316 338 0.96

5 12 3.2e-06 0.00023 21.3 0.5 1 23 344 366 344 366 0.98

6 12 3.3e-07 2.3e-05 24.4 0.7 1 23 372 394 372 394 0.99

7 12 5.2e-07 3.7e-05 23.8 5.2 1 23 400 422 400 422 0.99

8 12 2.1e-05 0.0015 18.7 7.2 1 23 428 450 428 450 0.98

9 12 3.7e-05 0.0026 17.9 0.1 1 23 456 478 456 478 0.96

10 12 2.1e-05 0.0015 18.7 3.2 1 23 486 508 486 508 0.98

11 12 0.00032 0.022 15.0 2.8 1 23 517 539 517 539 0.98

12 12 0.0014 0.099 12.9 6.1 1 23 544 566 544 566 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00044	0.031	14.6	0.2	3	23	230	250	228	250	0.98
2	12	9.4e-06	0.00065	19.8	1.2	3	23	262	282	260	282	0.96
3	12	2.4e-06	0.00017	21.7	0.8	1	23	288	310	288	310	0.98
4	12	1.7e-06	0.00012	22.1	1.8	1	23	316	338	316	338	0.96
5	12	3.2e-06	0.00023	21.3	0.5	1	23	344	366	344	366	0.98
6	12	3.3e-07	2.3e-05	24.4	0.7	1	23	372	394	372	394	0.99
7	12	5.2e-07	3.7e-05	23.8	5.2	1	23	400	422	400	422	0.99
8	12	2.1e-05	0.0015	18.7	7.2	1	23	428	450	428	450	0.98
9	12	3.7e-05	0.0026	17.9	0.1	1	23	456	478	456	478	0.96
10	12	2.1e-05	0.0015	18.7	3.2	1	23	486	508	486	508	0.98
11	12	0.00032	0.022	15.0	2.8	1	23	517	539	517	539	0.98
12	12	0.0014	0.099	12.9	6.1	1	23	544	566	544	566	0.98

Sequence Information

Coding Sequence: ATGGTAAACTTCACAGATGTCGGCATTGGCAATAACTGTCGTCTATGTGCCGTGCCCTCCTCGATCTTGGTGGATTTGTTCTCCACTGAGATCTCGAACCCGCCCGTCTCCGAAATGATGAACTCGTTTCTGAAAGAGGACTACTGCGTCAAGAAGGATGCACTGCCTCAGAAGGTTTGTCCCACCTGCTTGGTGGCCGCCCAAAACGCGTTTCACTTCAAGGAGAAATGCGAACAGAGCTACCAGTACTTTACCTGTTTAGCTACGAATGAAAAGACTTCGGCCAAGCATGAGGCAAACGAGCCCGAGGAAATCATGTTCGAGTTGGTTGGATGTGGGGATCCGCTGAGCACCGAGGTCGTGGCGGAGTCAGGAGAGGATAGACTGGGGAATTCCGAAGCTATAGAGTGCCTTGTCCCGCTTCACTGTAGTCCCGTGCCGGAGGAGAACAGCTTGTTATTAGAAATGCCTCCAAGCGATGGCGAGTTAGAAGACATAGACTGCAAGGAAGCCCCTAAAAATGTAACTGAAAAGCAAGCACGATCTCGATCGGACGAGGACAAAGAAGAAGGACAGTCTTCTGATGACTGGGTACCCGAGGACGACATGTCATCGATATCAAGCGATGATGAGACCACTACCGAAAGCAAACCCAATCCACTAGAGGGAAAATCATCATCCCTACTATGTCCCGATTGTGGAGCTCAATCCAAAACGCGAAGGGGTCTGGCCAGTCATATGCAGCGTCATAAAAAGGCGGTGAATGCGGAGCGGCCGCACTTGTGTGATAATTGCGGCAGAGGCTTTCGGACAAGCGCTCAACTAGTCATCCATTATCGCCGGCACACGGGAGAGCGACCCTTCAAATGTGATATCTGCTCGAAGGCGTACACCAATGCCCCGACCCTTCGGACTCATATGTTTACCCATGATAAGGATAAAGCACACAATTGTCCGGAGTGCAAGAAGACATTCTACACGGTTTCCACTTTGCGGGCGCACATGCAGTGGCACTCGGGAGACAAACCCTTTAAGTGTCCCGATTGCCCGATGGCTTTCAGCAAAAACTCCGGCCTAAAAATGCACAGCCGACAGCACACTGGTGAACGGCCGTATAAGTGCGATATCTGTGGCCAAGGCTTTATTCAAAACCAGCATTTGATCACCCACTTGCGGGTCCACAACGAAGACCGTCCATTTAAGTGCCCCGAATGCGACAAGTCCTTCTTCGAGAAGTCCAATATGAAGAAGCATCATCGCACTCACTCCGGAGTCAAACCGTACAAATGCGAGGAGTGCGGCCACCAATTTGCGCATGCCCATCACCTGAAAAACCACCAACGTGCCCACACTGGAGAAAAGCCATATAAATGCACTCAGTGCGACAAGGCCTTTGCCGCGAGCCAGTCGCTGGTGAAGCACATCGTTTGGCACGAGAGCAACCGCGATCGCGAGTTCATGTGCTCCCAATGCCCGAAAGGTTTCGACACCAAGAACAGTCTCCGGCACCATGAGAAGACGCACAAGAATACGGAGCCGAAGCAGATATACCAATGCCCCCATTGCGATGTTCGGTTTGGCTTTAAAAAGACTTACAACATGCACATCTCCAGCCATAAGATTCGACCACACCAATGCCAGCATTGCGAGGAGGGATTCTTTTCCTCGAAGAGCTACAAGAAGCACCTGAAAGTGCATAACCTGAAGAAATGA
Protein Sequence: MVNFTDVGIGNNCRLCAVPSSILVDLFSTEISNPPVSEMMNSFLKEDYCVKKDALPQKVCPTCLVAAQNAFHFKEKCEQSYQYFTCLATNEKTSAKHEANEPEEIMFELVGCGDPLSTEVVAESGEDRLGNSEAIECLVPLHCSPVPEENSLLLEMPPSDGELEDIDCKEAPKNVTEKQARSRSDEDKEEGQSSDDWVPEDDMSSISSDDETTTESKPNPLEGKSSSLLCPDCGAQSKTRRGLASHMQRHKKAVNAERPHLCDNCGRGFRTSAQLVIHYRRHTGERPFKCDICSKAYTNAPTLRTHMFTHDKDKAHNCPECKKTFYTVSTLRAHMQWHSGDKPFKCPDCPMAFSKNSGLKMHSRQHTGERPYKCDICGQGFIQNQHLITHLRVHNEDRPFKCPECDKSFFEKSNMKKHHRTHSGVKPYKCEECGHQFAHAHHLKNHQRAHTGEKPYKCTQCDKAFAASQSLVKHIVWHESNRDREFMCSQCPKGFDTKNSLRHHEKTHKNTEPKQIYQCPHCDVRFGFKKTYNMHISSHKIRPHQCQHCEEGFFSSKSYKKHLKVHNLKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615028;
90% Identity: iTF_00615028;
80% Identity: -