Dequ016428.1
Basic Information
- Insect
- Drosophila equinoxialis
- Gene Symbol
- -
- Assembly
- GCA_018150345.1
- Location
- JAECWI010000506.1:6879577-6882339[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.071 5.7 7.7 5.9 3 23 288 308 286 308 0.96 2 12 0.0012 0.098 13.3 0.5 1 23 314 339 314 339 0.94 3 12 0.0032 0.25 12.0 1.1 1 23 346 371 346 371 0.95 4 12 0.00028 0.022 15.3 1.9 1 23 383 405 383 405 0.98 5 12 2.4e-06 0.00019 21.8 0.2 1 23 412 434 412 434 0.98 6 12 0.0069 0.55 10.9 0.1 1 23 440 462 440 462 0.98 7 12 0.0067 0.53 10.9 4.0 1 23 468 491 468 491 0.98 8 12 0.0091 0.73 10.5 3.9 1 23 497 519 497 519 0.96 9 12 0.00015 0.012 16.1 3.6 2 23 526 547 525 547 0.96 10 12 4.1e-05 0.0032 17.9 0.3 1 23 672 695 672 695 0.96 11 12 0.023 1.9 9.2 1.0 1 19 701 719 701 723 0.94 12 12 1.8e-06 0.00014 22.2 4.1 1 23 729 751 729 751 0.99
Sequence Information
- Coding Sequence
- ATGAATGAGGGGAGTGCGTTATCATCGTACTCCATTCACTCGGTGTGCCGCATCTGTTTGAATCATTTGCAAAATGGTCCCGTCTTCGATCTATTCCTAATACCCGGACTGGCCAAGAAGCTGTGTGTGTGCACATCGCTGTCGGTGGAGCAGCAGGATGGATTCCCCCGCAATATATGCTGCACCTGCCACACCAAATTGGATGACATGCATCAGTTTCAGAAATTGTGCGTCGATTCGGTGCAGAAATTCCAATCGATGTTAAGCCAGAATATGTTTAGCAGCAGTTCCTCCTCCGCAACATTCGATTTGATGAATGTGATGACCACCAGCCATAATGAGGGGCCGGCAGATGAACCACCACTTGTGGCTGGTGGTGGTGGTGGTTGTGCTGCTGCTGCTGGTGAGGAGGATGATCGGCTTAATTTTGATCCTTTACTCAATCACAAAATGGAATTGATTGAAAACGAAGAAGATGTCTTCAAAATGCTCGAGAATGTCGATAAGGATGTGGAAGATGTGGAGAAACAAGAAGAGGGTGATGATGATGCGGAAGATGATGACTTTGAAGAGGATGATGATAACGACGATCATGATGCGGACTTTGAACCTCAATTAAGCAGCGATGTTGGCGACGATGATGACTTGCCTCTAGCTCAACGTTTGCGAATGAAAAAGAAACGCTCGAAAAGCGTCAAAAAAGAAAAGGAGTTTCTCTCAGGTTCTGGGGATGATTTTGTTTATGATGATGGAGATGAGTATGATGATGATGATGATGGCGGTAATGAAGGTGACTCCAAATCAAAGGCGAAACGCAAGAGGATACCAGCCGATGAACGTCATTTGCATCGTATCATCGATTGCCACATTTGCCATCAGAAGTTCAAGAAAGCAATTCGGTATGAGGAGCACATGAAGCATCACAACGATCTACTGCCCTTCCAATGTAAGGTGGAGACGTGTCGCAAGGGATTTACCACAGCCGGTGGCCTACGCCTCCACATTGATCATGCCCACACAGAGCTATCAGAAGTACATTCTTGCTCGGTCGAGGGATGTGGCAAAACCTTCCCTCGCGTCCGATTGCTAACCTTTCACATGAAGAAGGTCCACAACATATCGAAAGCGGCAGCTCCGCCAAGGGATTACCCCTGCTCCGAATGCGAAAAGGTCTTCCGTTGTCCCATGGCCCTGAAGAAGCATATGTATAAGCATGATGGCAAGGAACTGCCCTTCCCCTGCAATATTTGTGGCAAGCGATTTGTTATCAATTCCGCCCTCAAGGATCATTTAATGCGTCATGCCGGAATCAAGAACTATGTGTGTCCTTATTGCGGTGTAGGCAAGACGACACGTCAAGAGTGGAATACCCATATCCTAACCCATACCCAGGAGAAGAAATTCAAGTGCCATATATGCGAACATGCTTCGCACAACAAACAGAGTCTGGCCAATCACATCAAGATTGTTCATGAGAAGATTAAGAATTATGCCTGTCAGTATTGTGGCAAGACTTTTGGCAAGTCGCATGCCTGTAAAATCCACGAAATGACCCACACGGGAGAGAAACGATGCGAGTGCAAGGTTTGTGGCAAGAAATTCCTTTATCCAAAGAGTCTAACAAAGCATTTGAAGACGCATGAGAAGCGCGTGCTCCGTGCCATCGAAACTTATCGTCAGCGTCAAGTGGAGATGGGAGAAACATCAGGTCAAGGCGATCAACAGCAACAGCAACTGGATCAAGTGAACATTGGTCTGCCGAATTCCACGGGAAGTGTCACTGTGACCATAGCCGCCGAACCCGGCGTGGGTGATCAACTATTGTCCCAGAATGCCGCCGATGAGCTGCTCAAAGTTTGTGCTGAATCTGTGGCCACTATACCCAAAGATCCGCGTCGTGTCCAGCGTGTGGACATCTCGCAGTTGGCGGGCACAGCGGTTAATCCCATCTCCTCAGTCTCAGTGCCATCGTGGTCACCCCAGACAACGAACTTTACAAAAAAAGAGGGCAAACACATTTGTCCTGGCTGTGGTCAAGGCTTCAATAATATTGGCAACATGAAACGTCATTACAAGATTATACACGAGAAGGTCAAAGATTTCGCCTGTCGCTTTTGCCCACGAAGATTCGCCAAGGCGCAGACGCTCCGACATCACGAATGGATCCATACGGGCGAAAAGCCTTTCGAGTGCAAAACCTGCGGCACACATTTCCGCCAGGAGACCGCCCTAAAACGGCATCAGCGCACCCATGAGAACCGCCCGCCCGTCATCTCGTCCAAGTTCTATGCAGCTCGGGAGGAACTCGAGGAGCAAGAGCGCTCCAAACGCGAGGCCAAACGCAAGGCGGAGGCCAAACGTAAAGAGATAGCCGAAGCAGCTAAGGAGCAACTATCCACTTTACATAAATTGGAGTCCATTGACAAGCAATTGCATTCCTATGATGAGTATCAGGAGGCTGCCGCAGAGCGGGCAGCTGCCAGCGCCGAACTCCAGGCCCAACAGAACGAGGAGAACGAAGTCCGGCGACTGGCCGATGAGGAACGCATCAAAATTCAAGCGGCTGCCTATGAGCAGTTGCAGAAGTTGCAAGAGCAGCAGGAAATCGATAAGGCTCAAAGCTCCTACGATGGCTACTATGCGCAGAAGGCTCATGCCGATGGCACCAATTTGGATGCCCTCAAGATTGATCATGTGTGA
- Protein Sequence
- MNEGSALSSYSIHSVCRICLNHLQNGPVFDLFLIPGLAKKLCVCTSLSVEQQDGFPRNICCTCHTKLDDMHQFQKLCVDSVQKFQSMLSQNMFSSSSSSATFDLMNVMTTSHNEGPADEPPLVAGGGGGCAAAAGEEDDRLNFDPLLNHKMELIENEEDVFKMLENVDKDVEDVEKQEEGDDDAEDDDFEEDDDNDDHDADFEPQLSSDVGDDDDLPLAQRLRMKKKRSKSVKKEKEFLSGSGDDFVYDDGDEYDDDDDGGNEGDSKSKAKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCSVEGCGKTFPRVRLLTFHMKKVHNISKAAAPPRDYPCSECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVEMGETSGQGDQQQQQLDQVNIGLPNSTGSVTVTIAAEPGVGDQLLSQNAADELLKVCAESVATIPKDPRRVQRVDISQLAGTAVNPISSVSVPSWSPQTTNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPRRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERSKREAKRKAEAKRKEIAEAAKEQLSTLHKLESIDKQLHSYDEYQEAAAERAAASAELQAQQNEENEVRRLADEERIKIQAAAYEQLQKLQEQQEIDKAQSSYDGYYAQKAHADGTNLDALKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00571348;
- 90% Identity
- iTF_00612244;
- 80% Identity
- -