Basic Information

Insect: Drosophila eohydei
Gene Symbol: Znf574
Assembly: GCA_035045825.1
Location: JAWNOT010000072.1:2369060-2371295[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.7 1.8e+02 2.9 2.6 2 23 326 348 325 348 0.94

2 10 0.059 4 8.1 0.1 6 23 358 375 358 375 0.98

3 10 1.3e-05 0.00092 19.5 4.2 1 23 381 403 381 403 0.98

4 10 0.66 45 4.8 0.6 1 14 409 422 409 432 0.73

5 10 0.00037 0.025 15.0 2.5 1 23 440 463 440 463 0.97

6 10 0.16 11 6.7 0.4 3 23 471 492 469 492 0.92

7 10 0.49 34 5.2 0.2 2 23 504 526 503 526 0.93

8 10 0.0031 0.21 12.1 4.1 1 23 533 556 533 556 0.93

9 10 5.3e-07 3.6e-05 24.0 1.4 1 23 562 584 562 584 0.98

10 10 0.04 2.7 8.6 3.3 1 23 590 613 590 613 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.7	1.8e+02	2.9	2.6	2	23	326	348	325	348	0.94
2	10	0.059	4	8.1	0.1	6	23	358	375	358	375	0.98
3	10	1.3e-05	0.00092	19.5	4.2	1	23	381	403	381	403	0.98
4	10	0.66	45	4.8	0.6	1	14	409	422	409	432	0.73
5	10	0.00037	0.025	15.0	2.5	1	23	440	463	440	463	0.97
6	10	0.16	11	6.7	0.4	3	23	471	492	469	492	0.92
7	10	0.49	34	5.2	0.2	2	23	504	526	503	526	0.93
8	10	0.0031	0.21	12.1	4.1	1	23	533	556	533	556	0.93
9	10	5.3e-07	3.6e-05	24.0	1.4	1	23	562	584	562	584	0.98
10	10	0.04	2.7	8.6	3.3	1	23	590	613	590	613	0.97

Sequence Information

Coding Sequence: ATGGaagTAACAGCAGCCGAACCATGCTTGCTATGCCTAGAAGAGAATCCGTTGACCCTGAATGATTATATGGATGTATTTTCGGCAAAGGCGGCCCAACTGAATGTGGTTCAAATTATCAACAAACATTTTCCAATAGAGCTAATACAAAGTAGTGGGGAAACTCGGAAAATATGCCCGCTATGCTGGACAACAGTATCTGCTTTCAATACGCTGCACGATTTCGTGAGCTCCGCACAAAGCTCGCTGCGAGAAACCAAGGTGCTGCTCATGGAGGATGATCCCCTGACTCAAGGAAACTTTAAGCAGGCTAATGCCGATGCAGCCGATCTAAATGGTCGTAATTTCTTCTACCCTGAGGTCAAGATAGAGGAACATGAGCTGGAACAGTTGCCCAAAATTGAAGTTATTGAAGGTACGAGCAGCCTGCAGACATCCTCGCCCACTCGACGTCTGCGAAAACGTGTCAAAGCGGAGTCAGAACCCGGAAATGCCCAACCAGAATCGTTAGAGATTAATGCAAGTGAATCTCTAGATACAGTTGAAGCCCCGAAGAAACGTCGTGGACGACCACGCAAAAGCGAAGTCATTCTTAAACCAAGCCCAGCTGAAACGCAAACTGAGCAAAATTTAGATTTGGAATCGTGTCTCAAAGCAGAAGCGGAACATCCCGACGACTTTAGTGACGATGATCAGGACTTCTCTGCCGAATTCGTTGAAGGACTTGGCCATAGCGACGACAGCAGCGAGGAGAGTGCCCAAAGCGATGATGATTCTGATTTTACGGTTGGCAAGCCGGATGACGTTGAATTTGCTATCATACCGAAACGTACTCCAGTTCGACccaagaaatataaaaagcgtGCCAAGCCAGCGGAACCACGAGTTCGCATGTCCCGTGAACTGCTCGACCAGCGGAAGAAACAGCAGGAGGAATTCGATGCAATCATAGCCAAGTTCTTTAGCGATGTGTTGCCTTGCTCCATATGCAATCTGCTAGTGCATAACTTTACGGAGATGCAACGCCATCATCGACTCACACATCAAGTGGATCCGGGATATATGATTTGCTGTGGACGCAAGTTTACGCAACGTAAAGTGCTGGCCGAACATGTGCTGGTACATTGGAATCCCGAGCACTTTAAATGCACCACCTGCGAAAAGTCATTCCAAAATTCAAGACATTTGGAATCACATCAACAGGTTCACGTGTCCAAATTGACCTTCCAATGTGATCTATGCAGCAAAGCGTTCCTTAGCAAAACTGCCATCGACTATCATAAGCTGAACAAGCATGTTCCCAAATCTGAATTCAAATTCAGCTGCAGCGAGTGCAACAAAAAATTCCTGACTGAACGCAAGCTAAAGAATCATATGAACTCTATGCATGATCCGGAGAGCATTATCATTTGTGACAAGTGCGGCAAACAAATGCGCACGAAAATCATCTTGAAGAAGCATCAAGAGCTGATGCACTCAAACACCCCACGTCCAGAACCCGAGTTGAAGCAGTGTCAAATCTGTGGCGCCTGGTTGAAAGGCATGACAGGCCTTAAGCAGCATATGAAGAGCATACATGTGGAGAGCGCGGGCGAGCATCGCTGTCATGTATGCAACAAGATATCTCCAAATGCACGTGCACTGCGTCGTCACATCTATCACAATCATGAATGCGAGCGCAAGTTCAAGTGTACCATGTGCGATAAGGCCTTCAAACGTCCACAGGAACTCAAGGAGCACACATCTACTCACACCGGCGAAGTTTTGTACACCTGTCCCAATTGTCCGATGACCTTCTTCTGCAGCGCCAATATGTATAAGCATCGACAGCGATTGCATCGAGCACAGTACGAGGCGGATAAGAATCAGCCAAAGCCTCCAAATATATTGCAGCAAGCAGTAGGCGCAACGGCTGCCATGAAGATCAAACTGATGCAGAATACAAATGTTCCCAGCATAGAAACGGACTTGAAGCATTTCTAG
Protein Sequence: MEVTAAEPCLLCLEENPLTLNDYMDVFSAKAAQLNVVQIINKHFPIELIQSSGETRKICPLCWTTVSAFNTLHDFVSSAQSSLRETKVLLMEDDPLTQGNFKQANADAADLNGRNFFYPEVKIEEHELEQLPKIEVIEGTSSLQTSSPTRRLRKRVKAESEPGNAQPESLEINASESLDTVEAPKKRRGRPRKSEVILKPSPAETQTEQNLDLESCLKAEAEHPDDFSDDDQDFSAEFVEGLGHSDDSSEESAQSDDDSDFTVGKPDDVEFAIIPKRTPVRPKKYKKRAKPAEPRVRMSRELLDQRKKQQEEFDAIIAKFFSDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYMICCGRKFTQRKVLAEHVLVHWNPEHFKCTTCEKSFQNSRHLESHQQVHVSKLTFQCDLCSKAFLSKTAIDYHKLNKHVPKSEFKFSCSECNKKFLTERKLKNHMNSMHDPESIIICDKCGKQMRTKIILKKHQELMHSNTPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHVCNKISPNARALRRHIYHNHECERKFKCTMCDKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILQQAVGATAAMKIKLMQNTNVPSIETDLKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534856;
90% Identity: iTF_00573595;
80% Identity: -