Basic Information

Insect: Drosophila eohydei
Gene Symbol: Trerf1
Assembly: GCA_035045825.1
Location: JAWNOT010000005.1:320499-332583[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00014 0.0095 16.4 0.2 2 23 351 372 350 372 0.97

2 6 4.3e-06 0.00029 21.1 1.3 1 23 378 400 378 400 0.98

3 6 0.00041 0.028 14.9 2.5 1 23 406 430 406 431 0.94

4 6 0.00071 0.049 14.1 0.8 2 23 695 716 694 716 0.97

5 6 0.002 0.14 12.7 0.1 1 23 1830 1854 1830 1854 0.98

6 6 9.5e-05 0.0065 16.9 0.8 1 23 2005 2027 2005 2027 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00014	0.0095	16.4	0.2	2	23	351	372	350	372	0.97
2	6	4.3e-06	0.00029	21.1	1.3	1	23	378	400	378	400	0.98
3	6	0.00041	0.028	14.9	2.5	1	23	406	430	406	431	0.94
4	6	0.00071	0.049	14.1	0.8	2	23	695	716	694	716	0.97
5	6	0.002	0.14	12.7	0.1	1	23	1830	1854	1830	1854	0.98
6	6	9.5e-05	0.0065	16.9	0.8	1	23	2005	2027	2005	2027	0.98

Sequence Information

Coding Sequence: ATGGCTGCCATAAATACGGTACCTAAGAGCATACACCTGCCTTTGACGAATCTCAGCGCATCGCGCGTGCTGATGTGCAACGCATCTGTGGGCAGCGAGGGTTCCGTAACACTGCAACTGAGAGATGCGAATGCTTTGGAGGCAGCCgccagcagcacagcaacagcaacaacaacaacagcagcgacatcGTCACCAGGTCAAGCAAATGCGTCAGGACTAACGTCAGCATTGGAGAATGCGCTCACTATTGGCTATCCGGATCCGGATATGTTAGCAGATGTCTTGGGCACCATTCAGACAGCCTCTCTTAAGAACAgacaaagcagcaacaacaacagcaatagcaacagcaatagcagcagcaacagcaacagcaacagcaacaccaaaaGAAGCAttaatggcagcagcagccgaatcAGCACTGCACCAACAATTCTGAACAATACGATAGCAGCAACGAGCTCTGGCATTCGCCTGAACAGTCCCAACAGGATAACAATAACGCGACGCAGTGCTAGCAATAAGATTAGCGTACAAACTGTGAGCGCCTCGACGAATACAACCATTAGCAGCATTGGTGGCAGCAAGACCAACTACATCAAGAACTGTCTaatacgcagcagcagctgcagcaacacgGCCACCAATGTCACAACGTTGGCACAGATTATGAGCAatagcagcaccagcagcgccGCCAGTTTACTCAGTCAgcacaacaataatagcaactgcagcaacagcagcaacttcaGCAACGCCTCTTCTGTGGGCAGCAGCATTAGCAtaagcagcaccaccagcagcagcaccaccagcagtcAGAGTCACAgtagtagcaacagcaacagcaacagcaacgacagcaacagcagcagcggtcaCAGCCTAAGTTTCAAGAGCAACAGCCGACATGTTGCTGGCAtagtaacaacagcagcatccacGAACACCACTGCAACTGGCATTGGCATTATCACTGTCGACCACGCTCCCCGAAAGAGCCGACCCAAATTATCCTCGCCCACACGCCACGGCCCCCAACAGTGTCAGaTTTGTAGCAAGATCTTTGGAAATGCCTCGGCATTAGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATATATTTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGGAACAAGAAACCTTACGAATGTAAGGCGGAAGGCTGCGGCAAGTCCTATTGCGATGCTCGCTCCCTTCGCCGGCATTCGGAGAATCACCATGGCGGCGTGGCCACTCCGAACAACAACTCGCTCTCGCCCACGACTAGCAGCAACTGCGGCAGCGtgagcagtggcagcagtagcagcagcagcagtgtgggcgtggccagcaaCTCGCTTAGCCTGTCGCCGGCTACGGCGAGTGGAGATGCCAGCTCGCCAGACGGTGCCACCTGCATTCGCACCTACATTTCCACAGGCAGCACAGTGGTGGACGCAGCCACGGGCATTGCGTTATCCGACGAGCAGATCAAAGCCATGAATTTGCCCATTAAGACTGGGGTTACTTTGCTCTCGCCCACCACATCGACATCGTCGAACGCATCGTCTACAGCCTCCTCGTCCTGCTCCACcacaggcagcggcagcggcagcggcaacagtaacggcaatggcaatgctaTTGTCACCAGCTCACCGACAATTACGCTTAGCGACGGCACTACGCTTGAGGGCGATGGACTGACGCGCGAGCAACTCGATCTCATAAGCAAGATCATGCAGCAGACAAAGCAGACCAGTGCACAGGTCACCGTCTCCTCTCCCACCAGCGTCAGCTCCTATAAAATCAATACAGAGACAGCGCAAGTGTCGTCGCGCCCACGCACCTGGAACATGCAATTGCTCAACAACGCACAAAATGTGACTGTAACTGTGGAGGATGGCACAGAGGTAGCTGGATCGGCATCAACTTCAACCGATGAGGTCAAGGACGATGAGTTGAGCCAGCAGCTGGTGGCAGCCATCAATCCCCATCTGCTCAACATTGTTAAGATCGACAAGCCGGTGGAGTGCAACCTGTGCCATCGTAAGTTTAAGAATATACCCGCCCTCAATGGGCACATGCGTCTGCATGGCGGATACTTCAAAAAGGATCCGGAAACCAAGCGCACCGAGAAAAAGGACTCGAACGGACCTCCCTTACAGACGGCCAGCATAGGAGTGCGCGCCCTCATCGAGGAGAAAATCATAAGCAAACGGAAGGACATAAATAAGGGCGCCTTCGTAGTGCCTGCACCACCAAGCACCACATGCAACAGCGTTGGagtctgcagcagcaacagcaacacactgAGACGCTCGATAAGCGACCTGGAGAGTTTCCTCAACCCGAAATGCAGCACCACCAGTCTGAGTCAAGCActgtccagcagcagcagcaccaccacagCGGTATTGCCGGCAGCAACCACAATCAAGAGCAGCAACGGGCTAAGTATACAGCAGATTGGACTGCCGCAAAGCATCGAAATCTTCAGCGGAAGCCACAGGCAGCCGAAAACCCTCAGTCTAGGCAGTGGTGCCAACACCATAACCATAACCACCAACAATGTGCCTACCACGACCACCATGAGCGCCCTGACGGCATTGAAGGGCGGCGGCACCATCAATGGCATCTCCAGCAATGTGGATCCCAAGGACTCGACATTAATTGAGCTGCTCAAGCGCGGAACGCGCATTGCCGTCGCGTCGAAGAAGACGCAGAACAGCGCGAATCTGTTGCTGAGCAACGTGACGGGCACGGAGCTCACAGCTATCGGCAGCAGCGTCCAGACCGCTGGTCGACAGATAATcaccaacaacaatcgcaCCGTCATCATACCCTCAGATGTCCATGTGGTGTCCACCAAGAGCAAGCTCATTTCGAGCCAGGCCATCACAGCCAgcgacaacggcagcagcaacaataacaatgcaaCATGTTCTGCGAGCAGCAACATCTCGTTGCCGGATGGCACTCCGCTCTCGGTGGCCATTGCGAATAGCCAGGAAAATCTGGGCGTGAGTGAGGCAAGCACCATTACGGCCGGCGGCGGCGTTTATACGGTGACCTACACTAGCGATGCGGATGCATCGGATCTCTTCGACGACACTGAGGTATACAATGTCTCGGACACCGAAATGCTGCTCCAAACAGTGGACACTATGGAATTACTCAATGATGACGAGGAGGCGGTGCACAAGAGCGAACATTCCGAGGACTTTGCGCTGCTCAGCGAGACCGGTGAAACTGTTCACACGCAGCTAGTCAAAATGGAGCCGGGACTAACCAGCACGACTAACACCATGAATAAGACGACGCCGTTGCCCACCTTCCAGCAATTCCATTCCAAAGAGATTATCATGCAGAACAGCTCTCAAATTCAGGCCATTGCCAGCATGCGTAGCGGAAGCAATCTGGGCGTGCTCGCCTCTCCCTTGCATTCGCCAATAGCCTATCCGACGCCGCCGTCCAGCCACGAGAATATGGCCCAATCGTCGCCTTTCATAGAGGACGCTGCGGCTCAGTTCGTGGACGCCAGTCACACGTTCTTCGGCGACAAGACGGACTTCTCGCATGTATATTTTAAGACAGACGACGGCGAGTCCATGCAGCAGCTCACTGAGAACGACAACGAGAAGATACTCAAACTGAAGACGGTGCTCGAGGAAAGCAGCTTCGGCCAGTCCATCAAAGTGGAGGATCTGCTAAGCAGCACTGAAGATGATGCTGAATGCGACTTGCGTGAGTTTGCCGAGACGAATCTCTCGTTCCTGGATGAGGATCAGGAGTTCCTGAATGATTCACGAAACGCTACCTCTCCGCTGTCCGAGTCTTTCTTCACCAGCGGCATTGGCTCGGCCGAGGATGTTAAGCAAGTGCTGCGAGAGGTGCTGCCCGAGGAAAATATACAATTGCAGTTGAGTAGCGAGCAGCAGGGCGAGAACATCATTGATCTGTACTATTTGCCGGGTCTGGGCCTGCAATCCCAAATGATGCCCAACTCCGATGATCCGCTTTTGTCGTCCTCGCCACGCGAATTCGGCCAGCAACGTCAGGCTGTGCACACAAGCCCAGCTGCAACTACGACCGTGCAGCCTATCGAGCAGTTGCAGTCCACGACAGTGCTTtacgagcaacagcaacagcagcagcagcaacaattacagctgcaattgcaaatgcagtcccagcagcagcagcagcaacagccacaggagcagcagcaatcacaagaagagcaacagcagcagcaacagctaggaactcagcagcaacagctgcaattgcCACAGCTACCTGCAGTTCAAGGTGAACAgtcccaacagcagcaacagaccGATTTTATGCTCAGCAACTTTACGCCCGTGAACTGTCAAGCCCAATATATGGATGGCAATCAGCAGCCGATGATGTTGCAGCCGCTGAACAGTCTGCTGCAGCCAATGCTttacggcagcaacaacgctGCCAGCAATAAGCCCGCATTTAGCACGCTTCTCGGCTCCAACACGGTTCAGGCAACTGCACTTGATGCGAGCCTGCTCTTTGCCTGCGACGACTCAAAAAATAGCTGCAGCAAGCCCATGTTAGCCGGCTTATCCGCAGCCATTCCGACGCCGGTAGTTACGGCTGCGCCAAGTGTTGCAAACCTGCAGCCGTTGTCCAATCAGACGAACTCCATACTGAAGCGTCGCCTGCGGTCGAACGGAGCGCAGGATGTGCACAAGTTTTCGAAATTCCATACGCTATCGCCGCACCGCTCAAAGCTGCGCAAGCCATCCCGGACCCACTATACCCCTGCTCCAATACTCAATCCGGATCGCAAGGGCACCGGCCTCTACTGCAATGTGCGCAAGCAGCTTGGCCAGGGAATGTTTGACGTTTTCGACGATGACTTTGGTGATCCTGTGGGCTTGGTGGACTTCTGCGATGAGTCCAAGGTGAACCTTGGCTCCACCTATCAAGCGCAGATCCCAGCCTGCAAGCCACCAGACGAAGCCATCAAGGAGCCCATGTGCGCCGACCTAATGTGGGATCCAAGCGTCCAGCTAGACGATAAGATACTGATGCGTTACATAGATCTCAGCAAATCATCGGCCGTACCCATGGGCAGCCATTCCGAGGAGGTGGCCCTGCAAACGCTGCTCGACGCAAAGGGCAACTCCGCGGCAGCGGTGCTTAGCCTACTGCAGATGCAGTCCAGCGCATTCCAAATGAAATGGACTGCCTACGAGCTAGAGCAGTTCCTGCGCGGCCTCGAGAAACACGGCAAAGACTTTGGCAAAATCGCTAGTGAGCTTCACACGAAGACATCCGGGGAATGCGTgcaaatgtattatttttggAAGAAACTATGTGTGGACTACAAGGTATCGCACCTCAAAATGGAGCCAGTTCCTGCAAGCATCCCGACGGTGGAGCAGAAGCCCTACGTTTGCGAAATTGCCGACTGCTCGGCGAGCTTCAGTTCCAAGGCGGCGCTGCATGGTCATGTTCGCATACACGCTTATGGTagaaatgccagcaacaataatagtaacaacaacaacagccacaacaacagcaacaaccagcaTGCCACGGCAACTAGtgccaacaacagccacaattccagcaacaacaacaacagcagcaacaacaacaccaatagCAGCAACGCATGCATACCCCTGACTGGCAGCAGTCAACAGActagcaacaaccacaacagcaatgcaacagcaaccatAACGCACACTAATGGCAATAACAACACCAccgcgaacaacaacaatattatgaacaacaacaacagcatcgcTGGCATTTCCACAAACCCAACGATGCTTtcagtagcaacaacagcaatagcgacagccgctgccacagctgttgctgcggctgcggcagctTCATCCACAGCAACGAAAgacagtagcaacagcaacaattccAATATACCCAAGGACAGTGAATTTCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTGAAAAGCCGCAGCGCCCACATGAAAACGCATCGCGTACAAGAAGCGGAGCAACTAGCCAATTCCAAGCAGCAATCATCCacacttgttgttgccgtcactgcagcagcagcaaccacaaactcaacagcagcagcaacagcaatggccaCAGCAACTTCTTAG
Protein Sequence: MAAINTVPKSIHLPLTNLSASRVLMCNASVGSEGSVTLQLRDANALEAAASSTATATTTTAATSSPGQANASGLTSALENALTIGYPDPDMLADVLGTIQTASLKNRQSSNNNSNSNSNSSSNSNSNSNTKRSINGSSSRISTAPTILNNTIAATSSGIRLNSPNRITITRRSASNKISVQTVSASTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQIMSNSSTSSAASLLSQHNNNSNCSNSSNFSNASSVGSSISISSTTSSSTTSSQSHSSSNSNSNSNDSNSSSGHSLSFKSNSRHVAGIVTTAASTNTTATGIGIITVDHAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKAEGCGKSYCDARSLRRHSENHHGGVATPNNNSLSPTTSSNCGSVSSGSSSSSSSVGVASNSLSLSPATASGDASSPDGATCIRTYISTGSTVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSCSTTGSGSGSGNSNGNGNAIVTSSPTITLSDGTTLEGDGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETAQVSSRPRTWNMQLLNNAQNVTVTVEDGTEVAGSASTSTDEVKDDELSQQLVAAINPHLLNIVKIDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETKRTEKKDSNGPPLQTASIGVRALIEEKIISKRKDINKGAFVVPAPPSTTCNSVGVCSSNSNTLRRSISDLESFLNPKCSTTSLSQALSSSSSTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGSHRQPKTLSLGSGANTITITTNNVPTTTTMSALTALKGGGTINGISSNVDPKDSTLIELLKRGTRIAVASKKTQNSANLLLSNVTGTELTAIGSSVQTAGRQIITNNNRTVIIPSDVHVVSTKSKLISSQAITASDNGSSNNNNATCSASSNISLPDGTPLSVAIANSQENLGVSEASTITAGGGVYTVTYTSDADASDLFDDTEVYNVSDTEMLLQTVDTMELLNDDEEAVHKSEHSEDFALLSETGETVHTQLVKMEPGLTSTTNTMNKTTPLPTFQQFHSKEIIMQNSSQIQAIASMRSGSNLGVLASPLHSPIAYPTPPSSHENMAQSSPFIEDAAAQFVDASHTFFGDKTDFSHVYFKTDDGESMQQLTENDNEKILKLKTVLEESSFGQSIKVEDLLSSTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPEENIQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSDDPLLSSSPREFGQQRQAVHTSPAATTTVQPIEQLQSTTVLYEQQQQQQQQQLQLQLQMQSQQQQQQQPQEQQQSQEEQQQQQQLGTQQQQLQLPQLPAVQGEQSQQQQQTDFMLSNFTPVNCQAQYMDGNQQPMMLQPLNSLLQPMLYGSNNAASNKPAFSTLLGSNTVQATALDASLLFACDDSKNSCSKPMLAGLSAAIPTPVVTAAPSVANLQPLSNQTNSILKRRLRSNGAQDVHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGMFDVFDDDFGDPVGLVDFCDESKVNLGSTYQAQIPACKPPDEAIKEPMCADLMWDPSVQLDDKILMRYIDLSKSSAVPMGSHSEEVALQTLLDAKGNSAAAVLSLLQMQSSAFQMKWTAYELEQFLRGLEKHGKDFGKIASELHTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPASIPTVEQKPYVCEIADCSASFSSKAALHGHVRIHAYGRNASNNNSNNNNSHNNSNNQHATATSANNSHNSSNNNNSSNNNTNSSNACIPLTGSSQQTSNNHNSNATATITHTNGNNNTTANNNNIMNNNNSIAGISTNPTMLSVATTAIATAAATAVAAAAAASSTATKDSSNSNNSNIPKDSEFPCKVCGKVFNKVKSRSAHMKTHRVQEAEQLANSKQQSSTLVVAVTAAAATTNSTAAATAMATATS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00573254;
90% Identity: iTF_00519855;
80% Identity: iTF_00502459;