Basic Information

Insect: Drosophila eohydei
Gene Symbol: ken1
Assembly: GCA_035045825.1
Location: JAWNOT010000070.1:12517005-12519398[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.067 4.6 7.9 5.9 3 23 254 274 252 274 0.96

2 12 0.0003 0.02 15.3 0.5 1 23 280 305 280 305 0.94

3 12 0.0019 0.13 12.8 1.2 1 23 312 337 312 337 0.93

4 12 0.00095 0.065 13.7 4.0 1 23 347 369 347 369 0.97

5 12 0.0013 0.09 13.3 2.1 1 23 376 398 376 398 0.97

6 12 0.0073 0.5 10.9 0.5 1 23 404 426 404 426 0.97

7 12 0.039 2.6 8.7 3.5 1 23 432 455 432 455 0.97

8 12 0.019 1.3 9.6 4.1 1 23 461 483 461 483 0.95

9 12 0.0093 0.64 10.6 2.3 2 23 490 511 489 511 0.96

10 12 0.00019 0.013 15.9 0.8 1 23 600 623 600 623 0.95

11 12 0.00038 0.026 15.0 0.8 1 23 629 651 629 651 0.95

12 12 1e-05 0.00068 19.9 2.3 1 23 657 679 657 679 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.067	4.6	7.9	5.9	3	23	254	274	252	274	0.96
2	12	0.0003	0.02	15.3	0.5	1	23	280	305	280	305	0.94
3	12	0.0019	0.13	12.8	1.2	1	23	312	337	312	337	0.93
4	12	0.00095	0.065	13.7	4.0	1	23	347	369	347	369	0.97
5	12	0.0013	0.09	13.3	2.1	1	23	376	398	376	398	0.97
6	12	0.0073	0.5	10.9	0.5	1	23	404	426	404	426	0.97
7	12	0.039	2.6	8.7	3.5	1	23	432	455	432	455	0.97
8	12	0.019	1.3	9.6	4.1	1	23	461	483	461	483	0.95
9	12	0.0093	0.64	10.6	2.3	2	23	490	511	489	511	0.96
10	12	0.00019	0.013	15.9	0.8	1	23	600	623	600	623	0.95
11	12	0.00038	0.026	15.0	0.8	1	23	629	651	629	651	0.95
12	12	1e-05	0.00068	19.9	2.3	1	23	657	679	657	679	0.98

Sequence Information

Coding Sequence: atgaatGAGGGGAGTGAATACTCCATACACTCGATATGCCGCATTTGTTTAAATCATTTGCGAAACGATCCGGCATACGACCTGTTTCTTGTCCCTGGTCTGGCTAAGAAACTTTGTGTGTGCACTTCACTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCTCCACTTGCTACACCCGGCTGAACGACTTGCACGGATTTCAAAAGCAATGCGTGGATTCTATGCAAAAGTTTCAAGAAATGGTCGCCAACAATTATTTCACACCTGTTATTGCtgatataaatcaaattgacaaTGTCGATATACTGCAAGTACCACCCCCGGATGGAGAAATGGACGAAGATCGAATCAACTTCGATCCGCTCTTGAATACCAAAATAGAGATAATTGAAAACGAGGAGGACGTTTTTAAAATGCTAGAAGATGTCGACAAAGATGTGGAGGAAGTTGAGAAGGGGAAGGAGTCTTCAAGCGAAAGCGAAGCCGAaaatgacgatgatgatgttgacTTTGAAGCAAATAGTAGCGAATCTGACGACGCCATGCCCTTGTCACGTTTACGAAGCAGTACCAGAGCAACCAAAtcaaaggcaaagaaaaaagttgatgaagatgaagacgaTTCTTCCAGCTCTGACtctgataatgatgatgacgatgatgatgatgacgacgacgataagcccaaaacaaaaccaaaacgcAAACGCATTCCGGCCGCTGAGCGCCACCTGCACCGTCTAATCGATTGTCATATATGTCACCAGAAATTCAAGAAAGCAATTCGCTATGAGGAACACATGAAGCATCACAACGATCTGTTGCCATTCCAGTGCACTGTGGAAACATGTAAAAAAGGTTTCACCACGGCTGGTGGTCTACGACTTCATATGGATCACGCCCATTCGGAATTCTCTGAGGTACACGCCTGCACATTTGAGGGATGCGATAAGACATTCCCCCGATCTGTATTGCTCACGTTTCATATGAAAAAGGTGCACAAAGTGGCGAAGGCTGACACTCGCAATCATCCATGCACAGAGTGCGAAAAAGTTTTCCGTTGTCCAACAGCGCTTAAAAAGCATATGTACAAGCACACCGGCGAGGAGCTGCCTTATGCTTGTGAAATCTGTGGTAAACGATTCCATATACACAGTGTGCTAAGAGATCATCTCTTGCGCCATGCTGGCGTGAAGAACCACGTTTGTCCTTATTGTGGCGTGGGTAAGACAACTCGTCAGGAGTGGAACAAGCACATCTTGACGCACACTAGAGAAAAGCAGTTCCAATGTCGCCAGTGCGATCATTCGTCTCATAATAAACAGGCTCTGTCTAATCACGTTAAGGTGGTCCACATGAAGATTAAGAACTTTGCCTGCCAATATTGTGGCAAGACCTTTGGTAAATCACACGCCTGCAAGATCCACGAGAGACTCCACACTGGCGAGAATTGTTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAAAAGAGATTGACAAAGCATTTGCAGATCCACGAGAAGCGTGAAATACCACCGCCATCAGCTACTGGCAATCCGAGCGTCGAAGGAGATACCCAAAGTGCGCCGAATATGAACCAGGAAATGGCAGAGCCTGTGGACATTAAACCTGTGCCAATAGTTCCGCCTAAGCCCAAGAATTCACATAGAGTTGAGCGCGTGGATATATCTCAGCTGGCGGGAACGTCCGTTAATCCCATATCTTCGGTATCTGTACCATCTTGGTCACCACAAGTGAACTTTACCAAGAAGGAGGGTCAGCACATTTGTCCAGGATGTGGACGGGGCTTCAATCACATTGGCAACATGAAACTTCATTACAAGATCATTCACGAAAAGGTAAAGGATTTCGCTTGTCGCTACTGTCCTAAGCGCTTCGCCAAGGCGCAATACCTGCGCaatcatgaatatatacacaccGGCGAGAAGCCGTTCGAATGCAAAATCTGTGGCAAACATTTCCGTCAGGAGCAGGTGTTGAAGACGCATTTGAAGGTGCACGACAAGCCACCGAAGCCGCCAAAAGCCAAGAAACCACCAAAGCCTTCTGTTAGCAAAGCAAAGGGATTGAAGGTCGAGCTCAACAAAAAGCAACCAAAGATTTTCGACGAGTTCCAGGATCCCGCTGCAGAACGTGCTGCCGCAACTGCTGCATTGCTGGCTCAGCAGATGGAGGAGAATGAGGCCAAGCGAAAGGCGGAGGAAGAAACACGTAAGATTCAAGAGGCCGCATGCGAGCAGCTCAACAGACTGCAAAAACAGGTGCAAAGTGAGAAGGGCTCCTACGATAGCTACTATGGACAGAAAGCAGAGGCTGAGGGGACTAGCATGGATGCTCTTAAATTAGATCATGTATAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCSTCYTRLNDLHGFQKQCVDSMQKFQEMVANNYFTPVIADINQIDNVDILQVPPPDGEMDEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKDVEEVEKGKESSSESEAENDDDDVDFEANSSESDDAMPLSRLRSSTRATKSKAKKKVDEDEDDSSSSDSDNDDDDDDDDDDDKPKTKPKRKRIPAAERHLHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKADTRNHPCTECEKVFRCPTALKKHMYKHTGEELPYACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHSSHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREIPPPSATGNPSVEGDTQSAPNMNQEMAEPVDIKPVPIVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKAKKPPKPSVSKAKGLKVELNKKQPKIFDEFQDPAAERAAATAALLAQQMEENEAKRKAEEETRKIQEAACEQLNRLQKQVQSEKGSYDSYYGQKAEAEGTSMDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00508555;
80% Identity: -