Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000099.1:9347338-9351366[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.003 0.19 12.1 0.6 2 23 250 272 249 272 0.94

2 9 0.013 0.81 10.2 4.6 2 23 400 422 400 422 0.91

3 9 0.0063 0.4 11.1 2.3 3 23 508 529 506 529 0.94

4 9 0.00032 0.02 15.2 0.7 2 23 761 783 760 783 0.96

5 9 0.072 4.6 7.8 0.1 2 23 829 851 828 851 0.90

6 9 0.0099 0.63 10.5 3.6 2 23 898 920 897 920 0.96

7 9 0.097 6.1 7.4 4.2 2 23 934 956 933 956 0.92

8 9 0.0037 0.24 11.8 0.3 3 23 1016 1037 1015 1037 0.96

9 9 0.045 2.8 8.4 0.6 1 23 1121 1143 1121 1143 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.003	0.19	12.1	0.6	2	23	250	272	249	272	0.94
2	9	0.013	0.81	10.2	4.6	2	23	400	422	400	422	0.91
3	9	0.0063	0.4	11.1	2.3	3	23	508	529	506	529	0.94
4	9	0.00032	0.02	15.2	0.7	2	23	761	783	760	783	0.96
5	9	0.072	4.6	7.8	0.1	2	23	829	851	828	851	0.90
6	9	0.0099	0.63	10.5	3.6	2	23	898	920	897	920	0.96
7	9	0.097	6.1	7.4	4.2	2	23	934	956	933	956	0.92
8	9	0.0037	0.24	11.8	0.3	3	23	1016	1037	1015	1037	0.96
9	9	0.045	2.8	8.4	0.6	1	23	1121	1143	1121	1143	0.99

Sequence Information

Coding Sequence: ATGGCCGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAAGACACTGCGCTCTCCGATGTCTCCAACTCATCCACACTCAACACAAAtcgcggcggcggcagcagtaacaacagcagcagcaacacaaacaaccatagtaacaacaacaacaacaataacagtcaCACATTGCAGCCAAATGAAGCCACAGCAgacgcaacaacagcagccacaacaacaacagcagcagcagcggcaacaacaacaacaacaacatcaacaatgtCACCCACTCAACAGCAATTTCTGGACGCGgagccaaagtcaaagccgGGAAGCAGCACAAATGAAGCAGACATCATCGAGGACGATGCTGACGGTGATGGGGAAACGGATTCAACGGCAATGGCCgcgatggcagcagcagcagcaaatgcagcagccatgcagctgcaactgttggaGGCACTGAACGATGCGGCAAAAAAGCGACGCAAACAACACAATCCCAGTCGTCTGGAGGCGCTCAATTTGAGCGGTGGCGAGACGGAAGAGGGGGCAGCGGAGACGGCGCCAAATGCTGTTGTCGACTACGAGGAGAAGCTGTCGAAAATGCTTCTGCCCAAGTCCATTGAGAAGCTGAAGGAGACATTcgagctgttgcagcagcaaaagctgcaGCCAGAAGACATATCAGATGCGGaggaaaaacaacagcaacaacaacaggatcAATCGTTGGTGAACCCCTATCAGACCTATTGCAAGCAGTGCGGCGAGAACTTTGAGACAGAGTTCAAGCTCAGTTTGCACATGTTGCAggatcatcaacagcagcatcaacaggaacagcagcaacagttggccACGGACGAGCCCATGGATTTGTTATCCTCGATTAAAGTAAAGCTGGAACGCGCTGATAGTCCCACCCAGCTGgagctacagcagcaacaacagcagctggagctgacGAATggtcacagcaacaacaacaaagagcacGAACTCTGGCTACAGGCAATGGcacaacagcatcatcagcaacagcagcaacatcaacagcagccaggACTTCCAGGCATGCCGCCCGCTTTTGCGTTTCCCCCAGAGGCAGCTGCTCTGGGCTGGCCACTACTGGGTATGCCTGGCTTTCCTGGCGTCGAGGGTCTCAATCGTCCGCCGTTGCGCATCTTTAATCCTGAAGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAATACTTTCTCAAGACGCACAAGGCCAACAAACATGGTATCTTTGATCCTGCCGGTGATTTGGCCAGCACGCCAAACAACAATATCAGCAACatgaacaataacaacaacaacaacagcaacaacaaccataatggcagcaacaacagcaacagcaacaacaacgtcagtagtagtagcagcagctccaCTTCCATGTTTCAACAGCTGCAAATGCCACGCGAggtaccaccaccaccaccacaaaaACCAGAGCCACAGCtaacaccaccagcaccaccagcagtaCACTGCGACATCTGTTCCAAGCGCTTTACCAACATCTTTGCCATGCGTCGCCATCGCGCCAAGCAGCACGAGcaggccacgcccactgcctCACCAACGCCCCAACCGCGTCGCGGCAGCCCCAATGAGCGGCAATCTCCAGTCCAAACGCAGCCTGTGAAATTAGAACCTCTGGCGGATACGCAGTCCGTGTCTGAAATAAAGCCGTATCAGTTGCCGGATGGTTTTCGTGAGGATTTCACACTCGAGCAGGAAGAGCTTTCGTTTGCGCCACCTCCGCGCAAGCTGCCagcacagctgcagcagcaggcacgTGAATCAAACTGTGCTCCGGACAAGCTACGGCGATTGGGTGTACTGCTGCCGGAGGCGTTCTGCGAGCTGTGCTGCAAGGAGTACGCGAACAGATACTTCCTGCGCACGCACAAATGGAAGCGGCACGGCGTGTTTGTGCCACCCGAGGATCTGCAGCTGGGCGGCAAAGACGAGCAGCCACAAATGCCTGCCGGCTGGCCTTTTATGCCGCTCAATCTAATGCTAGCCAAGGCGGCTGCGGAGCATGAACAGCAGCCAGAGCAGGAGAATCAAAATGAAGACGAGCTGTTGCTCGAGGAGCAGCCAAGCAAGCGCATCAAGCTGGAACCCTACGACGAGTCGATGCCAGCAGAAAAGGTCGACAACTCAGTGATGGGATTGCAGAATCTCCAAAAGTTGCAAtcgatgctgcagcagctcaacGATTTCAATGGCAAGAGACCGCTCCCCTGTCATCTGTGCGGACGTGAGCTGGAGCATCAATATGCACTACGTGCGCATCTCATGACGGAGCACGCTAGTCAGCTGTTGCCCGAAGGACATCCCATGCTctaccagcaacagcagcaacagttgccgcttAAGCTATCGCCAGCGGGTGGTGTTTCGCCGacagcagctgcggctgccacgcccacacccaaTGAGCTGCGCTGTCAGCCGTGCGAGCGTGAGTTTGCCAACAGTCAGGAATTCAAGCAACATATCGCCGAGGTGCATCTGGGCCGCATcccaaccagcagcagcagtccgTTGCGCGAGGGCTTTTACACGCCGGAGCGTGCAACAGTTCCTCCGATTGCCGGTGCGCCTCCAGGACCACCACGGGGCGCTTATACGATCACACCGACGTCCAGCTACTGTGAGATCTGCAACAAGGAGCTGTGCAACAAGTATTTCATGAAGACGCACATGCAACGCATGCACGGCATTGAGATCGAAAATGGCGCCCAAATTGGCGGCGTTGTGTGCAACATATGCAACAAGGAGCTGTGCAGCAAGTACTTCCTACGCGTGCACAAACACAATACGCATGGGATTATCGAGGATGGAGCGCCACTACCCCAGCCACGTGGCCAAAACAGCGCACAGAACGGTATTAAAGCAGatgcccaacagcagcaacaacagcagcagcagcagcaacagttgctggaGCCGGAGGTGAATTTAACAACACTCCCTAGCGACTCTAGTGCTACTAATGAGCTGTGCCCACTGTGCGCACGTCAGTTCCGCAGCGCCAAGTGGTTGCGAACTCATCTGATGAACGAACATGGAGCCGCAGGTGTGGAGAAGCTGCGTGAGCTGgaattgcaacaacagcagccacccAGCTCTACCGGCAGCAAGCCCAACAGTCCCACGCTCAAGATACCCAATGGTAATCCGACTGGCGCCAATAATCTCGCACAGGCGCTGCAGAatgcacaacagcagctcTTTGGACAGATGCAATTGCCCAAAGGGATGCCGCTTCCCTTGCCGCTTCCTGGCATGTTTGAGCAGACGCCGCGCTTCAAGGAGTACCAGTGCTCCTTGTGTCCGTTCACCACGCCCTATTATGCATTCCTCTTTATACACGAACGCTCGCACGCATTGCTTAACACTGAGGAGACCCATGTGGGCGCCGAGGCGGAACTGCCACGCAACGACAGGGACAGATCCTTTGCCTTGGTACAGGGCAAGGCTAGAACCAAGCCTAGCAAAGAGCGTGCCGATGTGGAGATCGAACCCACGAACCtaaccaccaacaacagcaactcaaaGACAGCCACGCCCACGACTACGCCCACAACGTTACCCTCACCAggtgcagttgcaattgttgctggctCACCCAAAGTCCGATCCGCGACAGTAACGCCCATACCACGACGAcgcagcaccaccaacaccaacacaacCACCATCACCACCTCACCCAAGCCCGGAACGCCCAACGGCCTTGGCGCTCAACGTTCGGCGGCCACTTCACCCTTTGAGATGTGTAGCGATCTGGCCAATGGCAGTGGTAAACCCGCCAGCTATGCACAGCCAGACAAGGCCGAGGAGGCATATCAGATGCAGGCCTTCCATTTGGCACCCgctgatgccgatgctgaGGGCTTGTTTGCGCCAGCACTCGTCTATTTGCCGGTGCGAGTGCGGGCCTCCGAATCGACAACACTAAGCTTTAGGCTGACACCAGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGGGSSNNSSSNTNNHSNNNNNNNSHTLQPNEATADATTAATTTTAAAAATTTTTTSTMSPTQQQFLDAEPKSKPGSSTNEADIIEDDADGDGETDSTAMAAMAAAAANAAAMQLQLLEALNDAAKKRRKQHNPSRLEALNLSGGETEEGAAETAPNAVVDYEEKLSKMLLPKSIEKLKETFELLQQQKLQPEDISDAEEKQQQQQQDQSLVNPYQTYCKQCGENFETEFKLSLHMLQDHQQQHQQEQQQQLATDEPMDLLSSIKVKLERADSPTQLELQQQQQQLELTNGHSNNNKEHELWLQAMAQQHHQQQQQHQQQPGLPGMPPAFAFPPEAAALGWPLLGMPGFPGVEGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPAGDLASTPNNNISNMNNNNNNNSNNNHNGSNNSNSNNNVSSSSSSSTSMFQQLQMPREVPPPPPQKPEPQLTPPAPPAVHCDICSKRFTNIFAMRRHRAKQHEQATPTASPTPQPRRGSPNERQSPVQTQPVKLEPLADTQSVSEIKPYQLPDGFREDFTLEQEELSFAPPPRKLPAQLQQQARESNCAPDKLRRLGVLLPEAFCELCCKEYANRYFLRTHKWKRHGVFVPPEDLQLGGKDEQPQMPAGWPFMPLNLMLAKAAAEHEQQPEQENQNEDELLLEEQPSKRIKLEPYDESMPAEKVDNSVMGLQNLQKLQSMLQQLNDFNGKRPLPCHLCGRELEHQYALRAHLMTEHASQLLPEGHPMLYQQQQQQLPLKLSPAGGVSPTAAAAATPTPNELRCQPCEREFANSQEFKQHIAEVHLGRIPTSSSSPLREGFYTPERATVPPIAGAPPGPPRGAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRGQNSAQNGIKADAQQQQQQQQQQQQLLEPEVNLTTLPSDSSATNELCPLCARQFRSAKWLRTHLMNEHGAAGVEKLRELELQQQQPPSSTGSKPNSPTLKIPNGNPTGANNLAQALQNAQQQLFGQMQLPKGMPLPLPLPGMFEQTPRFKEYQCSLCPFTTPYYAFLFIHERSHALLNTEETHVGAEAELPRNDRDRSFALVQGKARTKPSKERADVEIEPTNLTTNNSNSKTATPTTTPTTLPSPGAVAIVAGSPKVRSATVTPIPRRRSTTNTNTTTITTSPKPGTPNGLGAQRSAATSPFEMCSDLANGSGKPASYAQPDKAEEAYQMQAFHLAPADADAEGLFAPALVYLPVRVRASESTTLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499185;
90% Identity: iTF_00616490;
80% Identity: -