Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:11370317-11371672[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.4 90 3.7 1.9 1 23 240 262 240 262 0.90

2 5 1.4e-05 0.00091 19.4 2.7 1 23 268 290 268 290 0.99

3 5 3.7e-05 0.0024 18.1 3.9 1 23 296 318 296 318 0.97

4 5 5.4e-06 0.00034 20.8 0.2 1 23 324 346 324 346 0.97

5 5 0.00036 0.023 15.1 4.0 1 21 352 372 352 376 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.4	90	3.7	1.9	1	23	240	262	240	262	0.90
2	5	1.4e-05	0.00091	19.4	2.7	1	23	268	290	268	290	0.99
3	5	3.7e-05	0.0024	18.1	3.9	1	23	296	318	296	318	0.97
4	5	5.4e-06	0.00034	20.8	0.2	1	23	324	346	324	346	0.97
5	5	0.00036	0.023	15.1	4.0	1	21	352	372	352	376	0.89

Sequence Information

Coding Sequence: atgctCAAAAACATGTGCAGAGTATGCGGCAGATATGCAGCCTACAAGAACTCGTTGAAAATCTTTGAAAATCAAGATATGCTGTGGAGCATTCAAGTTCTCACGGGCTTAGTCTTGGAAAATGCTGAATGTTTGCCAAAActgatttgtatttgctgcCAGACAGAACTGCGCGAGGCAATCAGATTCAGCGAAAGAGTCATTGCAGTTCAGAAGAGGCTTCTTTCAGCGTTGATTGAGGAGGAACTTCTGCAAATATCCGAAGAGTATAGGGAAGACGTAAGGGGCTCTTCGGGCAACTATACCCAAAATGTAACTAAAACGAAGCACAACTCAGAGGCACAATCCGAACCCACTACAAATCTACCTGGGACAGACGAAGAGCTGATCATTAAGGCGCAGCACGAAGGAAACGAAATAATCATAGAGGAACATGGCAAACAGGACGACTTAATGGAGTATGACTTCATCATTGACGATGATATAAGTCAACCGGCTGACCAGCAGGAATCCCAGTCCCAGAACATATCTGAAGAACACcaatttgccattgccagcgAAGATTATGAAAAATCTGCTGCCGATGGTTATATACTACCCGATAAGGGATCAGATGAAGAGTTTGAGGTGTTGGACAGAGTGTTAAACGACGAGATTGCCACGGCCCAGAGTATAGGCAAAAGGGTACCTGGGCGAAAGCGCATCGCCAATCTCAGATACGTTTGTGATGAATGTGGCAATCACATATCTGGTCGAATGGCATTTGAGCTCCATTGTAGACGACATCGGGGCGATAAGCAATACGAATGCGACATCTGCCAGGATCGTTTCTGCACTGGCTCCGAGCTAAAGCGTCACATGCGGAGACACACTGGGGAACGTCCATTTGCCTGCCAGTACTGCGGACGCTGCTTCACGGATTACAGCACCCGGGTGAAGCACGAGCGGACACACACCAATGAGCGACCCTATGCCTGCCAGAACTGTGGCAAAGCCTTCACCACTGCCTATATACTGAAGAACCACATGCTCATCCATTCCGGCGAGCGCGCCTTCAGCTGCGAGTTGTgcaataaaacttttattagACAAACGCATCTCGTTACACATTGTCGGTCGAGCGCTCATAAGCGCAATCTGGAACGACAAAACCAGGAGATAAAGATTGAGAGCTGA
Protein Sequence: MLKNMCRVCGRYAAYKNSLKIFENQDMLWSIQVLTGLVLENAECLPKLICICCQTELREAIRFSERVIAVQKRLLSALIEEELLQISEEYREDVRGSSGNYTQNVTKTKHNSEAQSEPTTNLPGTDEELIIKAQHEGNEIIIEEHGKQDDLMEYDFIIDDDISQPADQQESQSQNISEEHQFAIASEDYEKSAADGYILPDKGSDEEFEVLDRVLNDEIATAQSIGKRVPGRKRIANLRYVCDECGNHISGRMAFELHCRRHRGDKQYECDICQDRFCTGSELKRHMRRHTGERPFACQYCGRCFTDYSTRVKHERTHTNERPYACQNCGKAFTTAYILKNHMLIHSGERAFSCELCNKTFIRQTHLVTHCRSSAHKRNLERQNQEIKIES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517278;
90% Identity: iTF_00564926;
80% Identity: -