Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:1179732-1209581[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.005 0.32 11.4 0.2 1 23 1239 1262 1239 1262 0.96

2 8 0.014 0.89 10.0 1.0 1 23 1267 1290 1267 1290 0.96

3 8 0.00019 0.012 15.9 0.8 1 23 1507 1530 1507 1530 0.96

4 8 0.00091 0.058 13.8 0.5 2 23 1539 1560 1538 1560 0.97

5 8 0.046 2.9 8.4 0.3 1 23 1567 1590 1567 1590 0.96

6 8 1.8e-05 0.0011 19.1 1.4 1 23 1596 1618 1596 1618 0.97

7 8 8.8e-06 0.00056 20.1 0.4 1 23 1623 1645 1623 1645 0.99

8 8 0.011 0.68 10.4 3.4 1 23 1651 1673 1651 1673 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.005	0.32	11.4	0.2	1	23	1239	1262	1239	1262	0.96
2	8	0.014	0.89	10.0	1.0	1	23	1267	1290	1267	1290	0.96
3	8	0.00019	0.012	15.9	0.8	1	23	1507	1530	1507	1530	0.96
4	8	0.00091	0.058	13.8	0.5	2	23	1539	1560	1538	1560	0.97
5	8	0.046	2.9	8.4	0.3	1	23	1567	1590	1567	1590	0.96
6	8	1.8e-05	0.0011	19.1	1.4	1	23	1596	1618	1596	1618	0.97
7	8	8.8e-06	0.00056	20.1	0.4	1	23	1623	1645	1623	1645	0.99
8	8	0.011	0.68	10.4	3.4	1	23	1651	1673	1651	1673	0.99

Sequence Information

Coding Sequence: atgAGTGCCAACAAGCGACgaagttgcaacagcaacaacaacaacaacgataacagcaACACAGCTGATCAAATTGATAAGGATGTGCAGAGTGAAGAATGCCAAGGAGTGCCAACAATTGATGTGCAACGCTTGTGTCGCTGCTGTGGCAAAGGCGACATGGAATTGCTCAAACTGTTCGACGAGAGCGCTGAGACAGCCAATCAGAAGGCACAAACTCAATTTGCGACTGCGCAAATTCGCCAACGCCAAAAGAAGACAACAGACGAAAAAGCGAAAATagcacaaaaacagcaacatcaagaaaatcaacaacagcaagaacaacaacaacaacagcgcaaaAGTGATAATCCTGTGGAATATGCGCTGAGTGGAGCACACAGCAGCATGGACATTGTGTTAGAGGAGATGATCATTTGGAAGCTCAATATCTCACGTGACGATGGTCTGCCTCAGGAGATTTGTCGTCAGTGCAAGGCTCAATTCATAATGGTTGCGAAATTTCGGCGGCGATGTATGCGCGTCCAGCAGCGACTACACGACTACGACCAGGACATGATCGAGCACAAGTCACAGAGGGAGGAGGAGCGCACACAACAGTCACAGAGCAAGCCACAGGCAAATGAGACGTCCGCGGCAGATTACATGCATCTGCCACTGTCACAAATGGAGCGGAAGCGTCGCCTGGTGCCAAACACGGAATCATCGTCGCTGCCAAAATATATGAAGACTGATGCCACACAGCTGCTGACGCCGCCCAAGCTGCGGCGTATGCAGTTGCGAGTGCGCAATATGCGCACTGCCTCCTTGCCAGCCAGTAAAGTTGAGACTGAAACGGAAGCGGGAGCCACAGAAACGACCAGCGACTGTCGACTGAGTGAGACGAGGCAGCGAACGCCACAGAGATCGCCATACAGAGGGAGACTTATTCACATGCCATGGAAAACGAAAGCGGCACGCAAACAGATCTCGGAAACGTGGTCCACGTCCCTCTATCGAACGGACTCCGTGACGCCGGAAGTGCCCAAAGAGCAGGAGTCAGCTAATGGAACAGCTGCTttagcaaaagcagcagccgaAGCGGGTCCAAATTCATCGGAAGATTTGAGTGATCTGTCGGTGAATGTATGTCGAGGCttcgacaacgacaacggcagcagctccAATTCTTCCACAATAGTTAGCCCACAGCCAACTACAAATGTGAAGCTCAGGTTCCCACCAAAACACTGCTCGCCCAATAAAACTCGTGTTTTGCGGCGACAGGACAGACGCTGCTATGCGCCGGTCAAGAGGACGAGGCGCGTTTTCAAGAAGGCAAAGGCGGCAACTGAAGCAGCTAAGGTTGAGCTGTGCTGCGCAGAGGTGCTAAACAGTAAAACAACAGTGGCAACGGAGGCAGTTGACCAAATGCCAAATAGCTCTGCGAATGAGGAGcctaccagcagcagcagcagcaatagcagaaCATTCGAAAGTCCAGAGATAAGCATAGTCGATGAGCAGGAGAGTAAAATCATTGAGAAAGCAGAGAATGGAATGCCAGAAACAGGGTCAAATACACAGCAGGAAGAGCCGCAAGTCAGCTCGCCAGTAAGTCAAAGCGAAAATACAGAGGAAGAGCTGGAGCCTGATCATGCAATCAAATGTTCGCCAAACACTTTGGGCAATGATACTCAGGACAAGATGTTGATGGAACAAAAGGAAAGCATATCAGAAGAAGTGATAAAGGCAGAGGGGGAAGTAAATGGAACAGTAGAGACAACGCTTATGAGTCCTGTGCAGCTTGAGGAATTAAGCTCTTCCAGCATGGATCacatggagagagagagacggcaATCAGCAACGCCGGAGGTGCCAGCCGCAGAGTGCGAGGTAGAAGTGAGCCTAACAAATGAGGAACAAACGTCGGAGCAAATGTCGGATCAAGCATTGGATCAAGCATTGGATCAAATGTCGGATCAAATTTCGGAGCAAACTTCGGAGCTTATAATCAGTATACCGCTAGATGCGCTTGGCGAGGATCTACAGCGTAAACTATGCAACGAGTCGGAGCCGGCGACAAATGAGTTAGTCGACGAGTTGAAGAAACCAGATGGGGAGCTCAACGAGCCCGTGGAAACGGACGATGTCAATAACAATGAGAATGGCGAGAATTTTTGTCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTAGCACTCGcaaccaaacaaattgaagcaGAACCCAACGGAGGCGGTGacggtgatgatgatgatgatatggaGTCACTGGAGAAACTACCTAATCTGCAGCacgaggaggagcagcagcaacagcatcagcagccgtCACGCGCTTCTGCCAATGCCAGTTCCATGGATTTTTTGGCTGAATTCGAGAAGCATTGCGAAAAGTCGCTCAAGCTGCAGGCAGCTGGACAGGAGCTGGCGGAGGCCAAGCAACAGTTGGCGGTGGAAATGAACGATGTGGAGAATACACTGCACGGCATTCTCAATGAGATGCAGGATGAGCATCTCTATACGCCCGTCTGCACGCCCATCGATGAGTTCCTCACGCCCGCCGATTATGCGCCGCCAACGCCAGCGTCACCCAATCTCTTCGAGCAGCCAGCGGAGGCACAGCAaccactgcagcagcagcagcaacagcagaaggaGGGAAATCTCTTTGATAGCAGCACATTTAGTAATGAGCTGATTGGCTTTCAAAATGATATGCCCTGCTTTGAGAATATTGAGTCTACGCCGGAATCGATGGCTGTGCAGCAGAGCCTGCAGCTCGAGCTGACACAGCTCTTCAATGAGCTGCAgccagcacaacaacaacaacaacagcagcagcaacagcagtcaacacaacaacagcagcagcaacagttgcagctgcagcaggaaACTGTTAGCTATGAGGCACTATATCAAACAGCACCACTTCCTgtcgccaacaacaacaataacaataaattgcagGTCATACAAATGACGCCACAGGAGACTCTGTGGCAGGCACAGcctgcacaacagcaacagcaaccacaacagcagcctcaagcgacaccaacaacacaacTGCAATGGTCCACTGTGGGCGGCTTGGAGGCGATCAAGACGACGCCCAGTCTGGATAATctggacagcagcaacagcaacaacagcaacaataacaataacagcaacacaaccacctccaccacaaccaccaccTACTACATTAATGCCAGTGATCTCTAtcaaacacaacagcagcagcagcaacagcctaGCGAGTCTTATGCTTTACTCGACAGCAATGATAACTATGTgctggaacagcagcagcagcagcaacaacaaccacaacagcagcagcctatTATGATACTCATACAGCAGccggagctgcagcagccagtgGCTTCAGCCAGTAATCCGCAGCAGGCGCCGCTCCACATCAACTACAGCAATGAGCTGCAAGcttatcaacagcagcagcagcaacatccacatcaaccacaaccacatccAAAACCACAAGCACATCCACAAccacatccacaacaacaacaagtacaaaaTACAGTATTAGGCTTACCAGCAGTGGTGCCGCCGCCCACTCGTGGTCGCCCGCCCATGTTAAAGTGCCGCTTCTGTCAGAATGGACCGCGCTTCTCGAGCAGTCTGGAGTACAGTCGCCACTTCATTGGGCTGCATCCCGCCGACGCGCCATTTAACTGTCCGTACTGTCCGCTCGCCTTTGCTGGTCGCAGCAAGCGCAACCAGCACATACTCAGTAGCCACATTGTGCAGCAGTTTCACTGTGGTCAGTGCTCGCAAATGTTTCCCTCGCAGCGTGCGctcgatttgcatttgcagcgaTTACACATGCCACTCGCCACGGAGCCGACATCGGCATCGAGTGGCACAGCATCGGCTGGTGTCCGTCTAGAAGAGGTTCAACTGCGGATTGCCACCACCAATgatctgcaacagcagcagcagcagcagcgacaacatcAGCGTCAACCACTTAAGCAGCAATCAGTTGCACATATGCGTGCCTTGGAATTACAAACAAGCCCATCCAGACCACGCAGGACGCGCATACTGTGCTGCCCGGACTGCGAGGACTGCACTTCGGCCAGTGGCCACACTCAATGCAGCGTGCAGCCATACGAGGAGCTGAACACTTTGCAACCACCGCCCACGGTGCTGACGCCGCCGTCGACAATTGCATCGCTGCCGTCGCCGCAGCCGGCGCCGCATATAACGCTGCCATCACCGGAGCAATCGGAGCCAGACTCGACGACGGCAACGTTGCGGCAGTTCCGCAAACGTTGCACAGTCAACAGCTCGACAACACCGggggcagcagtagcagcccctacagcagcagcagcagcagtagtagcaacaacaacaacaacaatgctaaCAACTACTGCCGCCTCGCCATCGCCCtcgtcatcgccatcgtcgtcgACCATGGAGACAACAAGCGCCACACTGCAACTGGGCAAACTGCGTGGCACCCATCAGTGCGTCATCTGCGAGAAGCGTTTCACCAACGTTATTGCGCTGCGGAAGCATCAGCAACTGGCCCACGATTCGCAGACAACGATGCCGTGGGTCTGTCCAATCTGCAAGCGTGGATATCGGAAGCGCACCGATATGGATAACCATATGAAATCGCACGAGCCGAAGGGTCGACCCTATGAGTGCAACGAGTGCTGGGTGCGCTTTCCGGAGTTCAAGCAGCTGGCGATGCACAAGTTCACTGTCCACGAACTGATCAAGCCGCACACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGTGCGAGGCTTCGAGTGCGAAGAATGCGATGAGGCATTCGCCTACATCAAAGATTTGCGCAAACATCGTCGAACCCACAACAGCGAACTATTTTACAAATGCGATTACTGTCCGCGCACGTTTCTACATTTTACGCCCTATCGCGTACATATGAACACCCACCTGCCGCTGGGTGTGTTCCTTAACGACAAGATGCCCAGTAGCGTATGCAGCAAAACGGAGAATCCATCAAACACTGAAGAATCGCTGCTGCCATTGACGCCGCTGAGCAACTGCAATGgaaacagtggcagcaacagcggaTTAGAGGACTGTCCCGGCTCTGTGGAGATGGTGGTGGAGAGCAGCATGGCGGCGCCATCTTTGGATATGATTGTCGATACGCCATAA
Protein Sequence: MSANKRRSCNSNNNNNDNSNTADQIDKDVQSEECQGVPTIDVQRLCRCCGKGDMELLKLFDESAETANQKAQTQFATAQIRQRQKKTTDEKAKIAQKQQHQENQQQQEQQQQQRKSDNPVEYALSGAHSSMDIVLEEMIIWKLNISRDDGLPQEICRQCKAQFIMVAKFRRRCMRVQQRLHDYDQDMIEHKSQREEERTQQSQSKPQANETSAADYMHLPLSQMERKRRLVPNTESSSLPKYMKTDATQLLTPPKLRRMQLRVRNMRTASLPASKVETETEAGATETTSDCRLSETRQRTPQRSPYRGRLIHMPWKTKAARKQISETWSTSLYRTDSVTPEVPKEQESANGTAALAKAAAEAGPNSSEDLSDLSVNVCRGFDNDNGSSSNSSTIVSPQPTTNVKLRFPPKHCSPNKTRVLRRQDRRCYAPVKRTRRVFKKAKAATEAAKVELCCAEVLNSKTTVATEAVDQMPNSSANEEPTSSSSSNSRTFESPEISIVDEQESKIIEKAENGMPETGSNTQQEEPQVSSPVSQSENTEEELEPDHAIKCSPNTLGNDTQDKMLMEQKESISEEVIKAEGEVNGTVETTLMSPVQLEELSSSSMDHMERERRQSATPEVPAAECEVEVSLTNEEQTSEQMSDQALDQALDQMSDQISEQTSELIISIPLDALGEDLQRKLCNESEPATNELVDELKKPDGELNEPVETDDVNNNENGENFCQSATADSFNAAVALATKQIEAEPNGGGDGDDDDDMESLEKLPNLQHEEEQQQQHQQPSRASANASSMDFLAEFEKHCEKSLKLQAAGQELAEAKQQLAVEMNDVENTLHGILNEMQDEHLYTPVCTPIDEFLTPADYAPPTPASPNLFEQPAEAQQPLQQQQQQQKEGNLFDSSTFSNELIGFQNDMPCFENIESTPESMAVQQSLQLELTQLFNELQPAQQQQQQQQQQQSTQQQQQQQLQLQQETVSYEALYQTAPLPVANNNNNNKLQVIQMTPQETLWQAQPAQQQQQPQQQPQATPTTQLQWSTVGGLEAIKTTPSLDNLDSSNSNNSNNNNNSNTTTSTTTTTYYINASDLYQTQQQQQQQPSESYALLDSNDNYVLEQQQQQQQQPQQQQPIMILIQQPELQQPVASASNPQQAPLHINYSNELQAYQQQQQQHPHQPQPHPKPQAHPQPHPQQQQVQNTVLGLPAVVPPPTRGRPPMLKCRFCQNGPRFSSSLEYSRHFIGLHPADAPFNCPYCPLAFAGRSKRNQHILSSHIVQQFHCGQCSQMFPSQRALDLHLQRLHMPLATEPTSASSGTASAGVRLEEVQLRIATTNDLQQQQQQQRQHQRQPLKQQSVAHMRALELQTSPSRPRRTRILCCPDCEDCTSASGHTQCSVQPYEELNTLQPPPTVLTPPSTIASLPSPQPAPHITLPSPEQSEPDSTTATLRQFRKRCTVNSSTTPGAAVAAPTAAAAAVVATTTTTMLTTTAASPSPSSSPSSSTMETTSATLQLGKLRGTHQCVICEKRFTNVIALRKHQQLAHDSQTTMPWVCPICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGVRGFECEECDEAFAYIKDLRKHRRTHNSELFYKCDYCPRTFLHFTPYRVHMNTHLPLGVFLNDKMPSSVCSKTENPSNTEESLLPLTPLSNCNGNSGSNSGLEDCPGSVEMVVESSMAAPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00576613;
90% Identity: iTF_00518707;
80% Identity: -