Basic Information

Insect: Drosophila engyochracea
Gene Symbol: grau
Assembly: GCA_035042385.1
Location: JAWNLK010000107.1:3872514-3874845[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.062 3.9 8.0 1.1 6 23 302 319 302 319 0.98

2 9 0.00015 0.0095 16.2 2.8 1 23 325 348 325 348 0.93

3 9 0.00037 0.023 15.0 1.6 1 23 356 378 356 378 0.97

4 9 0.00022 0.014 15.7 0.7 2 23 384 406 383 406 0.96

5 9 0.04 2.5 8.6 0.0 2 23 412 433 411 433 0.96

6 9 1.2 76 3.9 4.4 2 23 442 463 441 463 0.91

7 9 0.00042 0.027 14.8 0.9 1 23 470 493 470 493 0.93

8 9 9.2e-06 0.00058 20.1 0.6 3 23 501 521 500 521 0.99

9 9 0.0011 0.07 13.5 8.9 1 23 527 550 527 550 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.062	3.9	8.0	1.1	6	23	302	319	302	319	0.98
2	9	0.00015	0.0095	16.2	2.8	1	23	325	348	325	348	0.93
3	9	0.00037	0.023	15.0	1.6	1	23	356	378	356	378	0.97
4	9	0.00022	0.014	15.7	0.7	2	23	384	406	383	406	0.96
5	9	0.04	2.5	8.6	0.0	2	23	412	433	411	433	0.96
6	9	1.2	76	3.9	4.4	2	23	442	463	441	463	0.91
7	9	0.00042	0.027	14.8	0.9	1	23	470	493	470	493	0.93
8	9	9.2e-06	0.00058	20.1	0.6	3	23	501	521	500	521	0.99
9	9	0.0011	0.07	13.5	8.9	1	23	527	550	527	550	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTGAACAGCGTCAGCGACaccattcaaatatttgaggGCGTCGGCCTATCACTGAACATAGCCACAGTGCTAGCCAAATACTTTTGGTTTCAGCCGAAATGCGATGATCCCATATCGACGGCCGTCTGTGGAGGTTGCTGGACGCGGGTCAGTGACTTTAACGAATTCTATGCGAGCGTGGAAAAGGCGCATCGTCTCCTCACCGAACGTTTCTCCCTCAAAGGCGGCGAGCCCCAGCAGGAGAAGCTCCATGCAAGTAGCCAGAGTCTGTTGGTCGGTGAGGGCAAGAAGGAGGCGATAGACATGCAGGAGGACACTAAAGATTTTCTTTATCATGCTGAGGATGATGACTTGGATCAGGATCAGGAACAAGACACGGCCGTCGACGATTTGTATGTCAGCGGGAACGAGAGCGATACAGCTGCATCGTTCAGCAACGAGCAGTTCCTCAACGATGTGCTTGCCCAGCAAACACAAGCAAATAGTGATCCTGCTGCAGAAGAAGTGCCCCCTCAACCGGAACCAGAACAAACAGCTGCTGTGCTACAGTCAACTCCTGAAGCTGTTCAGGAGCGTCGTGAAACGCGCTCCACGCGTGCTAAGAACAAAGCGCATCAGGTAAATGAATCGCCTCCAGCTGAAAAGAAAACATCAGCCAAGCGACGAGGCCGATCAAAAACGGAGAAAGTCGTTGCCAGCGATGCGGAGGAGTTGCCCAAGCACAAACGTTATGTGGACTACAAGAAATCCATGCTGGAGATTGATGAGAAGATCGCCCAACATATGCGCCTCACCTGCAGCGTTTGCCATGCGGGACAGGAGACTTTCCGGAAGCTGTGCGAGCACATGATGCAGATGCATCATCGCAAGGGGTATGCGGTTTGCTGTAACAGGAAATTCTACAAGCGCTCCTTTCTCACCGATCATATTGATCGCCACTCAAATCCCGAGAAATTTAAATGCGATCTGTGCGACCGAACCTTTGCGGACAAGCAGTGCCTGCGCAATCACGAGCTGCTCAAGCACCAGCCGGACGAGCAGAAGAAGTTCATGTGCGAGCACTGTCCCAAGCGCTATATCAAACAGTATCTATTGGATCAGCATCGGATCATACACAAGGAGCGCAATGTGCCCTGCAACATCTGCGACAGACGTTTTCCCAATGTTTCGAGACTGTGTACGCATGTGAAAATGGTGCATGGCAATTATGGCACGATGTGCGACATTTGCGCTCAGGTTATCCGAGGACCGGCTGCATTTGAACGCCATCAGCTGACGCACGCTGGGATTACGGAGCCAAAGGTGCAGTGCGAGATATGCGGTTCGTGGCACAAGAACAAGACCAGTTTGAAGAAGCATGTGCGTCGCCACAACGCCTCATCGGAGGAGTGCAAGTGCAACATCTGCGGCAAAGTGTCGCCCAATCGCAGCGCCATGCTCAGCCATCAGAGCTATGTGCACAATACGGATCGGGCGCATGGCTGCAGTGTGTGCAATAAGAAATTTAAGAAGGCCATCAATCTGAAGGAGCACATGGCCACGCATACGGGCGAGGTGCTCTACAAGTGTCCGCACTGTCCGAAGACCTTCAATTCAAATGCCAACAAGCATTCGCATCGTAAAAAATGTCATCCCAAGGAGTTCGAGGAGGCGCGCAAGGCACGTATACAGAAGCGCATGGGCGCCGATGCGATCGAGCAATCGAGCAAATCCCAAACTAGTCTAATCACAATCATGTCGGGCGAAACGGATAGCGAACTGGAGACGCACAATATACTGGTGaccacaacgacgacgacgacgacgtcggcGACGGCAGCGGCGGAGGAGGCAGAGCACAGCGATGATGATTTCAAGGGCGAGGACATTGAGTTTATGCTCGAACTCAGTCCACAGCCGGTCGAATAG
Protein Sequence: MICRLCLNSVSDTIQIFEGVGLSLNIATVLAKYFWFQPKCDDPISTAVCGGCWTRVSDFNEFYASVEKAHRLLTERFSLKGGEPQQEKLHASSQSLLVGEGKKEAIDMQEDTKDFLYHAEDDDLDQDQEQDTAVDDLYVSGNESDTAASFSNEQFLNDVLAQQTQANSDPAAEEVPPQPEPEQTAAVLQSTPEAVQERRETRSTRAKNKAHQVNESPPAEKKTSAKRRGRSKTEKVVASDAEELPKHKRYVDYKKSMLEIDEKIAQHMRLTCSVCHAGQETFRKLCEHMMQMHHRKGYAVCCNRKFYKRSFLTDHIDRHSNPEKFKCDLCDRTFADKQCLRNHELLKHQPDEQKKFMCEHCPKRYIKQYLLDQHRIIHKERNVPCNICDRRFPNVSRLCTHVKMVHGNYGTMCDICAQVIRGPAAFERHQLTHAGITEPKVQCEICGSWHKNKTSLKKHVRRHNASSEECKCNICGKVSPNRSAMLSHQSYVHNTDRAHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANKHSHRKKCHPKEFEEARKARIQKRMGADAIEQSSKSQTSLITIMSGETDSELETHNILVTTTTTTTTSATAAAEEAEHSDDDFKGEDIEFMLELSPQPVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577310;
90% Identity: iTF_00593372;
80% Identity: -