Basic Information

Insect: Drosophila engyochracea
Gene Symbol: ken1
Assembly: GCA_035042385.1
Location: JAWNLK010000099.1:13877588-13879897[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.15 9.5 6.8 6.3 3 23 231 251 229 251 0.96

2 12 0.0059 0.37 11.2 1.2 1 21 257 279 257 282 0.90

3 12 0.00046 0.029 14.7 1.8 1 23 289 314 289 314 0.93

4 12 0.00026 0.017 15.5 4.1 1 23 324 346 324 346 0.97

5 12 0.00019 0.012 15.9 1.8 2 23 354 375 353 375 0.96

6 12 0.007 0.44 11.0 0.5 1 23 381 403 381 403 0.97

7 12 0.028 1.8 9.1 1.9 1 23 409 432 409 432 0.97

8 12 0.018 1.2 9.7 4.1 1 23 438 460 438 460 0.95

9 12 0.0089 0.56 10.7 2.3 2 23 467 488 466 488 0.96

10 12 0.00017 0.011 16.1 0.8 1 23 573 596 573 596 0.96

11 12 0.0092 0.58 10.6 3.1 1 23 602 624 602 624 0.95

12 12 1.7e-05 0.0011 19.2 4.0 3 23 632 652 630 652 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.15	9.5	6.8	6.3	3	23	231	251	229	251	0.96
2	12	0.0059	0.37	11.2	1.2	1	21	257	279	257	282	0.90
3	12	0.00046	0.029	14.7	1.8	1	23	289	314	289	314	0.93
4	12	0.00026	0.017	15.5	4.1	1	23	324	346	324	346	0.97
5	12	0.00019	0.012	15.9	1.8	2	23	354	375	353	375	0.96
6	12	0.007	0.44	11.0	0.5	1	23	381	403	381	403	0.97
7	12	0.028	1.8	9.1	1.9	1	23	409	432	409	432	0.97
8	12	0.018	1.2	9.7	4.1	1	23	438	460	438	460	0.95
9	12	0.0089	0.56	10.7	2.3	2	23	467	488	466	488	0.96
10	12	0.00017	0.011	16.1	0.8	1	23	573	596	573	596	0.96
11	12	0.0092	0.58	10.6	3.1	1	23	602	624	602	624	0.95
12	12	1.7e-05	0.0011	19.2	4.0	3	23	632	652	630	652	0.97

Sequence Information

Coding Sequence: ATGAATGAGGGTAGGCAAAGCTCCATACACGCAATATGCCGCACTTGCTTGTCAAAAGTGCAGCATGTTGGAGCATACGATTTGTTTGTGATTCCAGGACTTGCCAAGAAACTGTGTGTCTGTACTTCACTCTCCGTGCAGCAGCACGATGGCTTCCCGAGAAACCTTTGCCCCAGTTGCTACACCCGGCTAAACGACTTACATGATTTCCAGCAGAGTTGCATGGACTCTGTACAAAAGCTGAAGGACTTGCTAGCTAGCAATTACTTTAGAATCCACACGGGCGAAGTTGACAGTTTTGATGTGCTGAGTGTGGTGGCGCCCCAGGATGCTGATGTGCCTGTCGAGGAAGATGATAATATCAACTTTGATCCGCTACTTAATACCAAAGTTGAAATAATTGAGAATGAGGAGGATGTCTTTAAAATGCTAGAATATGTCGACAAAGAAGCGGAGCAGGTAGATATGGAGAAGGAGTCCTCCAGTGGCAGCGAAAATGGCAATTATGATACTGAAGCGAATAACAGCGATTCCGACGACACCTTACCTCTATCCAGATTACGAAGTACTACAACAGAAGCTAATGCAAATGACGACGATGATAATGTTAAGGCCGACGATATAACCACGGTTAAATCAAAAAGCAAGCGGATTCCGGCCACCGAACGTGAACTGCGTCGTCTAATTGATTGTCACATTTGCCACCAGAAGTTCAAGAAAGAAATTCGCTACGAGGAGCACATGAAGCATCACAATGACCTATTGCCATTCCAGTGCACAGTGGAAACCTGCAGGAAGGGTTTCACTACTGCCGCAGGTCTGCGACATCATGGGGATCATGCCCATTCGGAACTCTGCGAACTGCACGCCTGCACCGTGGAAGGATGTGACAAAGCATTCCCCCGCACTCGAATGCTCACACATCACCTGAAAAAGGTCCACAAAATTGCCAAGCCTGAGATTCGTGATCATCCGTGCACGGAATGTGACAAAGTGTTCCGTTGCCCAACAGCTCTGAAAAAACACATGTATAAGCACACTGGCGAGGAACTGCCGATTTCCTGTAACATCTGCAACAAGCGCTTCCACATAAACAGCGATCTCAGAGATCATCTCCTGCGTCATGCCGGTGTAAAGAATCATGTGTGCCCCTACTGTGGCGTCGGTAAAACCACTCGCCAGGAGTGGAACAAACACATACTGACCCACACCAAGGAAAAGCAGTTCCAATGTCGCCAGTGCGATCATGCTTCCCACAACAAACAGGCTCTGGCCAATCACGTGAAGGTGGTGCACATGAAGATCAAGAACTTTGCGTGTCAGTATTGTGGCAAGACCTTCGGCAAATCGCATGCATGCAAGATCCATGAGAGACTTCACACGGGCGAAAATTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAGAAGAGATTAACCAAGCATTTGCAGATCCACGAGAAACGTGATATACCGTCTCCTGCAACCAATGTTAAGCCACAGGACGACGAGAGTCCACCAAATGTGGGCCAGCAGTTAACTGAGCTGAAGGATGCGAAGCCCATGACAGCAGTCCCCAAGCCAAAGAATTCGCATCGTGTTGAACGTGTGGATATATCGCAACTGGCTGGCACTTCTGTAAATCCAATATCATCGGTATCGGTGCCCTCGTGGTCGCCGCAAGTGAATTTCACAAAGAAGGAAGGCCAGCACATTTGTCCCGGCTGTGGACGTGGCTTCAATCACATTGGCAATATGAAACTGCACTATAAGGTGATACACGAAAAGATCAAGGATTTCGCGTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCTCAATATCTTCGACATCATGAATACACGCATACTGGTGAGAGGCCGTACGGCTGTAAGATATGCGATAAGCATTTTAGCCATGGGTCATCGCTTAGGAAGCATATGATTTCACACAACAGACCGCCAAAGGCCCCAAAGGCACTAAAGGTGCCGCCCAAGACAAAGGCGGAACAGCAGAGGCTAAAAATTGAGCTGAACAAGCGTCCGCCAAGAAACTATGAACAGTACCAGGATCCAGCTGCAGAACGGGCTGCAGCCACCGCGGAGTTGCTTGCCAAGCAGCTCGAAGAGAGCGAATCCAAACGAAAGGCTGAGGCCACGGCTCGGACTATTCAAGAGGCCGCCTGCGAGCAGCTTCAGAAACTGCAGAAGGAGCAGCTGATCGAAAAGATATCCTGTGATAGCTTTCAAGTACAAAGGTCTGAGACCGGCATAAGCGTGGATGCACTCAAAGCTgagaatatataa
Protein Sequence: MNEGRQSSIHAICRTCLSKVQHVGAYDLFVIPGLAKKLCVCTSLSVQQHDGFPRNLCPSCYTRLNDLHDFQQSCMDSVQKLKDLLASNYFRIHTGEVDSFDVLSVVAPQDADVPVEEDDNINFDPLLNTKVEIIENEEDVFKMLEYVDKEAEQVDMEKESSSGSENGNYDTEANNSDSDDTLPLSRLRSTTTEANANDDDDNVKADDITTVKSKSKRIPATERELRRLIDCHICHQKFKKEIRYEEHMKHHNDLLPFQCTVETCRKGFTTAAGLRHHGDHAHSELCELHACTVEGCDKAFPRTRMLTHHLKKVHKIAKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSDLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALANHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDIPSPATNVKPQDDESPPNVGQQLTELKDAKPMTAVPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKAPKALKVPPKTKAEQQRLKIELNKRPPRNYEQYQDPAAERAAATAELLAKQLEESESKRKAEATARTIQEAACEQLQKLQKEQLIEKISCDSFQVQRSETGISVDALKAENI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499101;
90% Identity: iTF_00542659;
80% Identity: -