Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:5099603-5101859[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 3.2 2e+02 2.6 0.4 3 23 36 58 34 58 0.91

2 8 0.047 2.9 8.4 0.2 2 23 125 147 125 147 0.90

3 8 4.4e-06 0.00028 21.1 3.0 1 23 165 188 165 188 0.98

4 8 8.8e-05 0.0056 17.0 2.1 2 23 303 324 302 324 0.96

5 8 0.0041 0.26 11.7 5.8 1 23 330 352 330 352 0.98

6 8 1.1e-05 0.00068 19.8 1.7 1 23 358 380 358 380 0.96

7 8 1.8e-06 0.00011 22.3 3.0 1 23 386 408 386 408 0.99

8 8 0.00015 0.0092 16.3 3.7 1 20 414 433 414 435 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	3.2	2e+02	2.6	0.4	3	23	36	58	34	58	0.91
2	8	0.047	2.9	8.4	0.2	2	23	125	147	125	147	0.90
3	8	4.4e-06	0.00028	21.1	3.0	1	23	165	188	165	188	0.98
4	8	8.8e-05	0.0056	17.0	2.1	2	23	303	324	302	324	0.96
5	8	0.0041	0.26	11.7	5.8	1	23	330	352	330	352	0.98
6	8	1.1e-05	0.00068	19.8	1.7	1	23	358	380	358	380	0.96
7	8	1.8e-06	0.00011	22.3	3.0	1	23	386	408	386	408	0.99
8	8	0.00015	0.0092	16.3	3.7	1	20	414	433	414	435	0.95

Sequence Information

Coding Sequence: ATGTGCTCCACATCGGTGCTGTGTCCATTGTGCGCTGTGCCCAGTTTCAATAGCATCgatgcactgcagcagcgTCTAATTAAGGCGGCCAACGGTCCCTTGGCCTGTCCATTTCCACACTGCACAGAGCAGTTCCTGGGCCTGGATAAGCTAACTATACATCTGTTTAGCCACACCAGTCTCATGAACAGAGTGGATGAAGTTCcaacagttgccacagttCCAGAAGTTGCAGTTAGTTCGCCACCCACGCCTGTTGCAGCTCCTGCTACTCCGCCGACTGCTGCGGCGCCCAAGCGGCGTGGCAAAAAGTCGCGTGCGAAGACTGTGGAGCCACCGCCTCAAGCACCGCTGCCTGCCACACCGCCGGCCCGCTGTGACATCTGCGAGTTTAGTTTCCGCAACGACGAGTTGCGCGACATTCACATCCGGCTGGTGCACGAGAATGGAGTGGATGGCACGGCGAcgcagccgctgcagcaacaggagcCGTACAAATGCCATCTGTGCTCCAAGACGTTTCGCATGAAGGGTTCGTTGCGTGTCCATCTCAAGGTGTTGCACACAGTTGGCATCAGTGGCAGTAAcagctccaacaacaacaacagcagcaacacaaattcgagcagcagcaatggcagcctGATGCTCAATCCCACGCCCAAGATAAGCATTTGCGATCGCATTCGGCACAAGGAGGCAACGGCTTTGGCTAACGGCAACACCATCACTtcaagcaacatcaacagcaacaacaactcaaacaactccaacagcagcagcagcaacaacaacaatactcaGCCTTATGCACTGAGTGGTGCCATTTGTATGCTGAAGCAGGATACGACAAGTGCAGCAGAGTCAGCGAACAGCTCGGAGTACGGAAGCACGCCCAAGAACTGGGAGTGTGATGTGTGCACCAAGCTCTTCACCACCAAGTACTTCCTGAAGAAGCACAAGCGGCTCCACACCGGCGAGATGCCCTACACATGCCAATACTGCGCTCGCACCTTCACCTTCCAGCAGTCCTACCACAAGCATTTACTCTACCACAGCGAGGTGAAGCCGCACGCCTGCGGCATCTGTGGACGGGCCTTCAAGGAGCTATCGACGCTACACAATCATCAGCGCATTCACAGCGGCGAGAAGCCCTTCAAGTGCGAGGTGTGCGGTAAATGTTTTCGGCAGCGGGTTTCGTTTCTGGTGCACACCCGCATCCACACCGGCGTTATGCCATACAAGTGTGAGCAGTGCCAGAAGACTTTCCGGTACAAGGTCTCGCTGCGGACACACAAATGCGCTGCTGGCCCTGAGGAGGCGCAGACGCCGGAGCAGCTGATCAAGGCATTGCTGGAATCGAATGTGGTCGGTGTGGTGGGCAATGTACAGACAGAGCATTCGGCAGCAGGAAGTGCGGCGAGTGCTGGGGATCAGGAGGCATTGCTCTCGCAGACGATAGATGACATTGTTGTCGAGAGCTGCCAGAAGCTGGGCATTTGTGGCGTGGAGCCACCACAGCAGGTAATCCTGGACAATGGCAATGTGCACTTCGATGGCAGCAATTCaccgctgcagcagctgcagaattTGCGCCTCTACTCGCCGCCACAGCAGCCGGAGCAGCCCAGCTCGGACGGGGAGCTCTTTCGCCACTTCCTCATGGACGCCACGTAG
Protein Sequence: MCSTSVLCPLCAVPSFNSIDALQQRLIKAANGPLACPFPHCTEQFLGLDKLTIHLFSHTSLMNRVDEVPTVATVPEVAVSSPPTPVAAPATPPTAAAPKRRGKKSRAKTVEPPPQAPLPATPPARCDICEFSFRNDELRDIHIRLVHENGVDGTATQPLQQQEPYKCHLCSKTFRMKGSLRVHLKVLHTVGISGSNSSNNNNSSNTNSSSSNGSLMLNPTPKISICDRIRHKEATALANGNTITSSNINSNNNSNNSNSSSSNNNNTQPYALSGAICMLKQDTTSAAESANSSEYGSTPKNWECDVCTKLFTTKYFLKKHKRLHTGEMPYTCQYCARTFTFQQSYHKHLLYHSEVKPHACGICGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCEQCQKTFRYKVSLRTHKCAAGPEEAQTPEQLIKALLESNVVGVVGNVQTEHSAAGSAASAGDQEALLSQTIDDIVVESCQKLGICGVEPPQQVILDNGNVHFDGSNSPLQQLQNLRLYSPPQQPEQPSSDGELFRHFLMDAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324381;
90% Identity: iTF_00518645;
80% Identity: -