Basic Information

Insect: Drosophila engyochracea
Gene Symbol: wdn
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:3970059-3973258[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00017 0.011 16.1 0.6 1 23 319 341 319 341 0.98

2 7 0.06 3.8 8.1 1.8 2 23 352 372 351 372 0.93

3 7 6.5e-07 4.1e-05 23.7 1.1 1 23 378 400 378 400 0.99

4 7 4.1e-06 0.00026 21.2 4.0 1 23 406 428 406 428 0.98

5 7 0.00021 0.013 15.8 3.0 1 23 434 456 434 456 0.97

6 7 4e-06 0.00025 21.2 0.8 1 23 462 484 462 484 0.96

7 7 9.6e-05 0.0061 16.8 2.3 1 23 490 513 490 513 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00017	0.011	16.1	0.6	1	23	319	341	319	341	0.98
2	7	0.06	3.8	8.1	1.8	2	23	352	372	351	372	0.93
3	7	6.5e-07	4.1e-05	23.7	1.1	1	23	378	400	378	400	0.99
4	7	4.1e-06	0.00026	21.2	4.0	1	23	406	428	406	428	0.98
5	7	0.00021	0.013	15.8	3.0	1	23	434	456	434	456	0.97
6	7	4e-06	0.00025	21.2	0.8	1	23	462	484	462	484	0.96
7	7	9.6e-05	0.0061	16.8	2.3	1	23	490	513	490	513	0.98

Sequence Information

Coding Sequence: ATGGAGTGTAAAGGCAAAGCAAAGAGAATGAAAGAAGAGGCGCCAAGCAAAAAATTGCCGCCTAAATTATATGGCGGTGATTATGCGGCCAATGCAAGCACGCCCACCAAAGCGGCCCACGATGAGATACTGAGCTCCTTGTTGCGCATCAACAATTTCGATTCCATATCGAGCATCAAAGACGAATCCCTCGACATTGATCTGTCCGCCTGCGTCACAATCAGCTCGGCCAGCTTCATCAATGGCAATAGCCTGTCGTCTACGGATTTTTGGCGCGTTCTCGACGAGAGTGCACAAAACAATACGGAATTAAATCTATCCTCAGATGTGTGCCGCGAGGAATTGAGTGcgcccagtcccagtcccacaCCCAGTGCGAATCTATCGAATGGCAGCGCCAATGACAATCATAATTCCGAGTTCAATGTTACGTTCCTGCGGCCGGAGCCGCCAAATGCGTTCACGAACTCGCCATTTAAAAAgatcacaacaacagcaacgactaCGGCGACGGCGGCGACGACGCCAGTGAAGCTCCAATCACCGGAGCAATTGCCAATTGTGCAGCAGATGGTTTCGCAACGTAAGACACGTTTACCCGCTGCGGCAGCGGTACGGTTAAGGGTCTTCAAGGAGGAGCTCTTCGATGAGAAGGAGATGTCCCCCAAGGGAGCTGAGCTGTTGACCAAAGTGGAGCATTCGGAGTCGGATCATTTGCCGCCAGCGTTTACCATATTccagcaaccacagcagcaacaacaacatcaacaacatcagcagccgcCAGTGAATAATATGCCGCCACCGGCTGTGCCGTTGGATTTCAATGGTAAACTAGAGCTGGAAACGCCGCCGCCACCTCTCTACAAGTGCCTGGACTGCAACGGCCTGATTCTTGACAATCAGCAGTTGGTGAGTAGCCACAAGGCGGCAGCGCATCGATTGCGCATCACCTACAACTGCACCGAATGCCAGCGCGAGTTTGAGCTCTTGGCGGGGCTCAAGAAGCACCTGAAGACGCATCGCAGCGAGGGACGCAAGGATACGTGGAAAAAGTGCCCAGACTGTGGCAAGTGTTTAAAGTTGGGCAGCATGTGGATGCACCGGAAGATCCACAGCGATAATAAGAAATATCAGTGCGATATTTGTGGCCAGAAGTTTGTgcagaaaatcaatttgacgCATCACGCACGCATCCACTCTTCGGAGAAGCCGTACGAGTGCCCCGAATGCCAGAAACGATTCCAGGAGCGCTCGCATCTGCAGCGCCATCAAAAGTATCATGCACAGACGCGCTCCTATCGCTGTGAGAAATGTggcaaaatgtacaaaacgGAACGTTGCCTCAAAGTACACAATTTGGTGCATCTGGAGCAGCGTCCCTTCGCGTGCAATGTGTGCGACAAGAGTTTCATTAGCAACTCCAAGTTGAAGCAGCATTCGAATATTCATACGGGCATGCGACCGTTTAAATGCAACTATTGTCCGCGCGACTTTACAAACTTTCCCAATTGGCTGAAGCATACGCGACGCCGTCACAAGGTCGATCACAAGACTGGCGAGCATCTCGAGAACATTCCCTCCTACTGCTCCAAGAAATCAACGACAACGAAGGCACAGAaagcagctgccgccgctgctgctgctgctgcggcggcggcaacggcgacaacaGCCGGATCTTCAGCATCAGACGTGCTGCCACTCAGCACAGCTGAAGGAGAGGCAAAGTCCACATCCTCCTCAACGCCGCAGACAGCCAAAGTGCCGTCAGCTGCAGCGCCAGCTCCACCAGTTAAGCAGGCACGCAAAAAgaagcaaccacaacaagcaACTCTTGCCGCTTTGGGCATCACTTTGCCAGCGGGAACAGCACTTCAGCAGGTGCATCCGCCGCAGCCGCTACCACAGTCCACAAGCAAACAGTCAAATGTTGCTCCGCTGCTGGTACCACcaccacaagcagcagcagcaatagcaaccaCCGCTCCAGCCAAGCAGATAAAAGCGAAACGAGAACGCAAACAGTTGGCGCccaaacagctgcaacagaagCCATCTGCGCCAGTGGGCAGCACTCCTCACACGGTGCCCGTTGCAATGCcgcaaattaaaaaggaaCCGTTGCAGACACAGGGTCCATTCCTGGACCTTCATGGCCTTAGCCTCACATCGGCCGAGGAGCTGATCATGGAGCAGGCCCTCGAGATGGAGGAATGCGGATTGTATGATACACCCGTGGGCAACACTGAAATGGGCACCTCAGACAATGCAACCGCCTCGGATGCAGCGACTGCCCTACactttcaaatcaaaaacgaATTACCCGATGAACTTCTACCTGACGACGATTTCTtGTCCCACAAACCCAATAATGGCAATCGCATAGCCTGTCCATCGCTGGAATCATCACCGTTCTCCTCGCCCGCATCCATGGAACTGGGTGCGGTATCCACCACTACCACCATCAGCAGTAGCATCACCAAACCCACATCAGCTGTGAATGTGAACTCGGGTCGCACCGCCAACTATTATTTGCCAGCATTTACGCTGAATGCCCAAGGCAAGTTGACCAGTTGTACGACCAGCACTGGCACTTGCACGGGAACAGGAGCGACCAATGCAATTGCCAATGGACCGACAACAGTGTCTGTTGTGAATATGCCAATGTTGGTACACTCGAATCAGATGTTGCCATCCGTGGACACTCTGCTCTTTACAACCCAGACGGGCAATCGATTCTTCTCGGGCAAGGCAGCCTCAGGTGGCGCCTCAGTCTCAACGACGACCCATTTGACATGA
Protein Sequence: MECKGKAKRMKEEAPSKKLPPKLYGGDYAANASTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASFINGNSLSSTDFWRVLDESAQNNTELNLSSDVCREELSAPSPSPTPSANLSNGSANDNHNSEFNVTFLRPEPPNAFTNSPFKKITTTATTTATAATTPVKLQSPEQLPIVQQMVSQRKTRLPAAAAVRLRVFKEELFDEKEMSPKGAELLTKVEHSESDHLPPAFTIFQQPQQQQQHQQHQQPPVNNMPPPAVPLDFNGKLELETPPPPLYKCLDCNGLILDNQQLVSSHKAAAHRLRITYNCTECQREFELLAGLKKHLKTHRSEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACNVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTTKAQKAAAAAAAAAAAAATATTAGSSASDVLPLSTAEGEAKSTSSSTPQTAKVPSAAAPAPPVKQARKKKQPQQATLAALGITLPAGTALQQVHPPQPLPQSTSKQSNVAPLLVPPPQAAAAIATTAPAKQIKAKRERKQLAPKQLQQKPSAPVGSTPHTVPVAMPQIKKEPLQTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDTPVGNTEMGTSDNATASDAATALHFQIKNELPDELLPDDDFLSHKPNNGNRIACPSLESSPFSSPASMELGAVSTTTTISSSITKPTSAVNVNSGRTANYYLPAFTLNAQGKLTSCTTSTGTCTGTGATNAIANGPTTVSVVNMPMLVHSNQMLPSVDTLLFTTQTGNRFFSGKAASGGASVSTTTHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01323591;
90% Identity: iTF_00514391;
80% Identity: -