Basic Information

Insect: Drosophila engyochracea
Gene Symbol: Sry-delta
Assembly: GCA_035042385.1
Location: JAWNLK010000101.1:13999176-14000432[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.5e-05 0.0022 18.2 0.3 2 23 180 202 179 202 0.93

2 7 0.00011 0.0072 16.6 0.1 1 23 208 230 208 230 0.98

3 7 1.9e-06 0.00012 22.2 1.1 2 23 237 258 236 258 0.97

4 7 5.6e-05 0.0036 17.6 1.4 1 23 264 286 264 286 0.98

5 7 0.00026 0.016 15.5 2.2 3 23 295 315 293 315 0.96

6 7 1.9e-06 0.00012 22.2 3.9 1 23 322 344 322 344 0.98

7 7 0.0078 0.49 10.8 0.5 3 23 392 413 391 413 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.5e-05	0.0022	18.2	0.3	2	23	180	202	179	202	0.93
2	7	0.00011	0.0072	16.6	0.1	1	23	208	230	208	230	0.98
3	7	1.9e-06	0.00012	22.2	1.1	2	23	237	258	236	258	0.97
4	7	5.6e-05	0.0036	17.6	1.4	1	23	264	286	264	286	0.98
5	7	0.00026	0.016	15.5	2.2	3	23	295	315	293	315	0.96
6	7	1.9e-06	0.00012	22.2	3.9	1	23	322	344	322	344	0.98
7	7	0.0078	0.49	10.8	0.5	3	23	392	413	391	413	0.95

Sequence Information

Coding Sequence: ATGAATTCATGCTTCTTTTGCGGAGCCGTTGACTTACACGGCACGGCAAACTATGAATCGCTCAGTACAAAGGTGCCCTCGTCCCAGAAATCTGTGTCACTGGTGCTCACCCATCTCGCCAGCTGTATGAAAACCGAAATGAATCTGAAGAAGGATACAAAGCTTTGTCCGCGCTGTTTTCAGGAAATGGCCGAATATGATACGATTATGGTGAACCTAATGGTTGCCCAAAAGAAACTTACAGCTCAATTGAAGGAGGCCCTCAAATCCGAGTTCGAAGACGAAACGCTAATCGATGATTTTGGGGATAAATCCGCCCAAGACGATGCCGAAGCTGAGGCATTGTTTGAGGAGCTCGTCAAAGAGGACGATCAAGAGGTGGAAATTAAGGAGGaatatgatgatgataacgctgacgacgacgatgatgatgaggaggaggagttcCTATGCGAAGTACGGCCCGATGAGGGCGGCGTTAAGCGCGAAAGTGCCGCCGACGATCAAAAGAAATTCATGCCGAAGCGCATTCGGCAGGAGTGCGACACTTGTGACAAGGTCTTCTATGCCCGCTATCAGCTGCAGAAGCACATCAGCGAGGAACACAACAAATCGCAGGCGCACGTCTGTCCCATCTGCGGCGTCATCCGCCGAGACGAGGAATATCTGGAGCTGCACATGAACACGCACGAGGGTAAAACGGAAAAGCAGTGCCGCTACTGCCCCAAGAGCTTTTCGCGTCCCGTGAACACGCTGCGACACATGAGGGCGCACTGGAACAAGAAAAAGTATCAATGTGAGAAGTGTGGATTGCGCTTCTCGCAGGACAATCTGCTGTACAATCATCGGTTGCGACACGAGGCCGAGGAGAATCCCATtatttgcagcatttgcaaCGTTTCGTTCAAGTCGCGGAAAACATTCAATCACCATACGCTGATCCACAAAGAGAATCGACCACGGCATTATTGCACCGTATGCCCCAAATCGTTCACCGAGCGCTATACACTCAAAATGCACATGAAGACCCATGACGGCGATGTTGTCTATGGGGTGCGAGAGGAGGTGCCCACAGATGACCAGGTGGTCGAGGAGCTGCAAGTGGATGTGGATGAATCCGAGCAGGCCGTCACGGTCATAATGTCGGACAACGATGATCCCACTTCCGGTATTTGTCTCATTTGCAATGTGAACTACGAGAGCAAAAAGGAGCTCGCCCATCATTTACAGTATGAACACGCTGTAATGAATAAttag
Protein Sequence: MNSCFFCGAVDLHGTANYESLSTKVPSSQKSVSLVLTHLASCMKTEMNLKKDTKLCPRCFQEMAEYDTIMVNLMVAQKKLTAQLKEALKSEFEDETLIDDFGDKSAQDDAEAEALFEELVKEDDQEVEIKEEYDDDNADDDDDDEEEEFLCEVRPDEGGVKRESAADDQKKFMPKRIRQECDTCDKVFYARYQLQKHISEEHNKSQAHVCPICGVIRRDEEYLELHMNTHEGKTEKQCRYCPKSFSRPVNTLRHMRAHWNKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCTVCPKSFTERYTLKMHMKTHDGDVVYGVREEVPTDDQVVEELQVDVDESEQAVTVIMSDNDDPTSGICLICNVNYESKKELAHHLQYEHAVMNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508558;
90% Identity: iTF_00576545;
80% Identity: -