Basic Information

Insect: Drosophila engyochracea
Gene Symbol: GFI1
Assembly: GCA_035042385.1
Location: JAWNLK010000113.1:3904935-3924571[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0002 0.013 15.8 3.6 1 23 523 546 523 547 0.96

2 6 0.0003 0.019 15.3 0.5 1 23 552 574 552 574 0.97

3 6 3.5e-07 2.2e-05 24.5 1.9 1 23 580 602 580 602 0.98

4 6 1.7e-05 0.0011 19.2 4.2 1 23 608 630 608 630 0.97

5 6 2.1e-07 1.3e-05 25.2 2.5 1 23 636 658 636 658 0.98

6 6 4.3e-05 0.0027 17.9 5.0 1 23 664 687 664 687 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0002	0.013	15.8	3.6	1	23	523	546	523	547	0.96
2	6	0.0003	0.019	15.3	0.5	1	23	552	574	552	574	0.97
3	6	3.5e-07	2.2e-05	24.5	1.9	1	23	580	602	580	602	0.98
4	6	1.7e-05	0.0011	19.2	4.2	1	23	608	630	608	630	0.97
5	6	2.1e-07	1.3e-05	25.2	2.5	1	23	636	658	636	658	0.98
6	6	4.3e-05	0.0027	17.9	5.0	1	23	664	687	664	687	0.97

Sequence Information

Coding Sequence: ATGAACGTTGGCAAGATGCAAGCGCCTGGCCAGCACCAGCATCCGCATCATTTGCTGCATTCGGCTGCATCCGCTGCGCCGCCACCGACGCAACAGCATCATCTGCCCATCGATTATAGTTTGGGCAACTTTAAGCCCGCCATTGCTGCCGATTTTCCCGGCGGCCCCTTTGTCGCCAgcccccagcagcagcaatcatcCTCAGCCTCCTCCACGTCGCCGCCCTCGATTGTCACGTCAAGCGCTTCGCTGCAGGTGCGAGATCTCAGCGCGTTGACCACAATGGCAGCGATACCCTCGCCCACACAGCTGCTCCATCAGCGCATGCAACAGGCCCAAATCACTGTGGATgcccatcagcagcagcagcagcagcaacaccaacagcagcagcagcaccaccaccaccaccagcatcagcagcatcaacaaatgCCGCCGACGGCAACATCGCCCCACGATTACGCGCCCATGTCCGCCTTCAAGGCGGTGCTACCCAAAAAGCGAACTTCCGACGATGCGTCGCACCCCTTTAGCATAAGCAGATTGGTCAAGACTGAACACCTGACGGCAATTGTGGCCGCTGCTGGCCTaaagccgccgccgcctctgcctctgccggCGCACAGCGTCGCCTTGGCggaggacaacaacaactccatcTCGATGCTGAGCAagaaccaacagcaacagcacgaACCACACAATATTCAGCGTCCCAAGCTGTTGCCTTATTTAAGCGCCAGCGAGCAACTTCGTCAATCGCGCTCCCGATCGAGATCGCGTTCGCGCAGCGCCTCCCACTGCTCCTCGCAGATCGACATGGACGATGCGGATAGCAGTCATGAGCGATACTCACGGCATTCGCAACGCTCGCTGCACTCGAGATCCCGCTCCCGCTCCAGATCACGATCTCACTCGAGCAGCTCCTCTGTGGAGCTGGAGGTGGACTCGCCACCAGGTAGTCCCAGCATCAGTTCACCCAGTGCCGCCTCTGTTTCCGCATCCGAGCTGCTTATCAcggccaacagcaacatcagcgcCAAGAAATCGGATCTCTTCTCCGTCTCCGCGCTCCTGCGTCGCGATGAACCCACAACACGTCGTGTCCGTAGTCCACCGCTTGGCCTCGCCGGCGCCTCGACTGCTGCGCTGTCAGCGCTGCCCACCAATCCGCTGGAAGTCATGCGCCAGAGCTACCAGCCCAACTACGACGCTGCCATGTTTCAGCGCCCCATCTTCTCACCAGCGCTGCCCTTCTTTGCCGCCATTGCCTTCCACCagggtcagcagcagcaacagcaacagcaatccgGACTAGTCACTAGTTACCATCCGGACTCACAGGAAAATCTCTTCCGGCTGCGCAGCCTAATGGTGCCACTGCAATCTGCTGGCCAGAATGGCtcaacagcggcagcggcggcggcggcggcggcagcagcagcggctgttGGTGTGGGCGTGCCACCCGGTGGCGGACATTTGGGTCTGCCACATCCGCCGCATCTGCACTTTCATCACATGACGGCCAAGTGGCCGGGCCTGCATCAATTTAGCGACCTGTACTCGTGCATGAAGTGCGAGAAAATGTTCTCCACGCCCCATGGACTCGAGGTGCACTCGCGCCGCACCCACCACGGCAAGAAGCCCTACGCCTGTGAGCTATGCAACAAGACCTTCGGCCACGAGGTCAGCCTCAGCCAGCACAGGGCGGTGCACAATGTGGAAAAGGTCTTTGAGTGCAAACAGTGCGGCAAGCGCTTCAAGCGCTCCAGCACCCTCTCCACCCATCTGCTCATCCACAGCGACACGAGGCCTTATCCCTGCAGCTACTGCGGCAAGCGATTCCATCAAAAGAGTGATATGAAGAAGCACACCTACATTCACACCGGTGAGAAACCGCACAAGTGCCAGGTGTGTGGAAAGGCTTTTAGCCAGAGCTCCAACCTGATAACGCATTCACGCAAGCATACCGGCTACAAGCCATTCTCCTGCAAGCTGTGCCACAAGTCCTTCCAGCGCAAGGTGGATCTGCGACGTCACAAGGAGACACAGCACACAGATCTGCGCGTCCATCTCGGCAAGGTGGACTTCATGTCTGCCGCAGCGGCAGCCGCAGCCGTTGCCGAACTGAATGGAGCTCCGGGTGCTGGCATGAGTATGTCAGCTGGTGGTGCCGCACCACAAACCGGTACAGGAGCGCCTGTCAGTGCCACCACGCCGGTCAACTCGATGAATTGCCAAAAGGTATCACTGCTGGCATAA
Protein Sequence: MNVGKMQAPGQHQHPHHLLHSAASAAPPPTQQHHLPIDYSLGNFKPAIAADFPGGPFVASPQQQQSSSASSTSPPSIVTSSASLQVRDLSALTTMAAIPSPTQLLHQRMQQAQITVDAHQQQQQQQHQQQQQHHHHHQHQQHQQMPPTATSPHDYAPMSAFKAVLPKKRTSDDASHPFSISRLVKTEHLTAIVAAAGLKPPPPLPLPAHSVALAEDNNNSISMLSKNQQQQHEPHNIQRPKLLPYLSASEQLRQSRSRSRSRSRSASHCSSQIDMDDADSSHERYSRHSQRSLHSRSRSRSRSRSHSSSSSVELEVDSPPGSPSISSPSAASVSASELLITANSNISAKKSDLFSVSALLRRDEPTTRRVRSPPLGLAGASTAALSALPTNPLEVMRQSYQPNYDAAMFQRPIFSPALPFFAAIAFHQGQQQQQQQQSGLVTSYHPDSQENLFRLRSLMVPLQSAGQNGSTAAAAAAAAAAAAAVGVGVPPGGGHLGLPHPPHLHFHHMTAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCSYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAAVAELNGAPGAGMSMSAGGAAPQTGTGAPVSATTPVNSMNCQKVSLLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586160;
90% Identity: iTF_00553235;
80% Identity: -