Basic Information

Insect: Drosophila engyochracea
Gene Symbol: pita
Assembly: GCA_035042385.1
Location: JAWNLK010000019.1:5774635-5776655[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00085 0.054 13.9 0.1 1 23 216 238 216 238 0.95

2 9 1.4e-05 0.00091 19.4 1.1 1 23 244 266 244 266 0.96

3 9 9.6e-07 6.1e-05 23.1 2.7 1 23 272 294 272 294 0.99

4 9 0.00044 0.028 14.8 0.2 1 23 300 322 300 322 0.96

5 9 0.00019 0.012 15.9 0.1 1 23 328 350 328 350 0.95

6 9 4e-05 0.0026 18.0 0.3 1 23 356 378 356 378 0.94

7 9 0.0055 0.35 11.3 5.3 1 23 384 406 384 406 0.98

8 9 0.25 16 6.1 0.0 2 23 442 463 441 463 0.95

9 9 0.02 1.3 9.5 1.3 1 23 469 492 469 492 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00085	0.054	13.9	0.1	1	23	216	238	216	238	0.95
2	9	1.4e-05	0.00091	19.4	1.1	1	23	244	266	244	266	0.96
3	9	9.6e-07	6.1e-05	23.1	2.7	1	23	272	294	272	294	0.99
4	9	0.00044	0.028	14.8	0.2	1	23	300	322	300	322	0.96
5	9	0.00019	0.012	15.9	0.1	1	23	328	350	328	350	0.95
6	9	4e-05	0.0026	18.0	0.3	1	23	356	378	356	378	0.94
7	9	0.0055	0.35	11.3	5.3	1	23	384	406	384	406	0.98
8	9	0.25	16	6.1	0.0	2	23	442	463	441	463	0.95
9	9	0.02	1.3	9.5	1.3	1	23	469	492	469	492	0.91

Sequence Information

Coding Sequence: ATGTGCAAAAATGCGGAGACGTTGCTGCGTCAATATCCGCTCACCGGCAAATGGCCAAATCCATTGGAAAAGCCTCGGGCACCGTTGGTatccaaacaacaacagatggCTGTCAACAAGGAGTCCGAGGCACAGCCAAAGAAACTGCTCAACTCGTTGGCAAAGAGCAACAATGTGCAGATCGAAAGTGTGCAGGTGCTGGAAACTAACCTCCTCACCAAGAAGCTACTCAATTCGGCAGCAGTGAGCACGGCAGAGCCACCAATTCCGCCACGTGGATCTCCCCAGAAGCGACTACAATCGAAGTCATCGTATCAGATTAAGGTGGAGAACAATGAAGAGCTGTCCATGGATGATGTGCACAATCTGTTAGCGGACGTCTCTGGCGAATTGGAAGAAACTGCGGATATTTTAACGGCGCCATCAACGATGATTTCGTCAGGCAAACCCAAAGTTCTCAACAAATCGTCGATGCGACTACTCAACAAGGGCGCCACTACGTCCGTGGAGCCACGGTTGGCCAAACCCCAGATCAAGCACTACGAGGATGGCAATGTGGCGCTCGTTACTGAAATACTCCAACCCGATGACATCGATGCGTCCTCGgatccaattaaaaatgctgcaCCGGTTGCGACCAATGTCTTCTCGTGTCCAGATTGCGATCGCTCTTTTCCATTGATGCAGTTGCTCGACATACACATGGTGAACCACACACGAACGCGCAGTTTTCAATGCCAGGAGTGCGAGAAGGCCTTTTTCTCCAAGTACGATCTGCAGAAGCACAATATTATCCACACCGGCGAGCGTCCGTACAAGTGCAGCGTCTGTGAGAAGGCCTTCACCCGCCGGGCGCTGCTACATCGGCACGAGCGCACCCACACGGATGTGCCCAAGTTCATTTGCCTGTACTGCGAGAAGCCGTTCATTTCGCGCGAGGAGATGGAGAAGCATGCGGAGCGCCACACCAAAAAGAGACCCTTTCAATGCGGCGTCTGCCAAAAGGCGTTTGCCTTCAAGCAGGGTCTGGAGCGGCACGAGGTTATCCACAGCACTAATCTGCCGTTTTCGTGCCAGTATTGCAGTCGTAGCTTTGTGACCGCTGGCAAATTGGCACGCCATCTGGTTGCCCATGCTGGGAAGCGTGTCTATCCATGCAAATACTGTTCCAAGTCGTATCTGTTGTCGCATCATCTGTCGCGGCATGTGCGCATGCATAAACAGGCAGCGGCTGCTTCGTTCACCTGCAGCATCTGCAAGGATACGCATCAATCTTATGACAGCCTGGTGGATCACTCCTCGATACACGCGAGTGTCTCGCTGATCTGTCCGCTGTGCAAGGCAAGCATTGCTGACGCGGATAGCCTGGAGCCGCACATGCAGGCGCACAAGGAGAGCGAGCGACATGCCTGCGAGTTCTGTGATTTCATCTTCCTGAGCTCCGCCCATTTGCAAAAGCACATCGAGGATGATCATGTGGTCGATATGGTGCCGTATCAGAATGAAAGCGAATACGAGCAGGGCGTCAACAAAGAAGAGGAGGTCGAGGAGGAGTCCGAATTGATGGAGGAATTGTTGGCTGAAATGTCGCCATCGCCGTCACCGTCGCCCACTCCAACAAAAATACGCAAACTGAATCCGATTGCAAAGACTACTCAGACACAAGATGACAAGACCAAACGAGAGTCCAGATCCAAGATAATCAAACCGACACCGGAGATTTCGCCAGATAATCGAAAAAGAGCCCGAAGCGTCCACAAATCCCCCGCTGCCTCGTCCGTTTCACCCGAAAGCAAGCGGCAGACGCGTCGCCACGACAGCAAGGAGAGATCCTTGAAGCCCAACGATTCTGCAAAAAGATCTACTAAGAAGATTGTCGTGGAGCAGAGTCGGCAGCCCAGCAAACATCGCAATTTAAAGGTTTCCAGCTCCAAGTCTAAAAGCcccaaataa
Protein Sequence: MCKNAETLLRQYPLTGKWPNPLEKPRAPLVSKQQQMAVNKESEAQPKKLLNSLAKSNNVQIESVQVLETNLLTKKLLNSAAVSTAEPPIPPRGSPQKRLQSKSSYQIKVENNEELSMDDVHNLLADVSGELEETADILTAPSTMISSGKPKVLNKSSMRLLNKGATTSVEPRLAKPQIKHYEDGNVALVTEILQPDDIDASSDPIKNAAPVATNVFSCPDCDRSFPLMQLLDIHMVNHTRTRSFQCQECEKAFFSKYDLQKHNIIHTGERPYKCSVCEKAFTRRALLHRHERTHTDVPKFICLYCEKPFISREEMEKHAERHTKKRPFQCGVCQKAFAFKQGLERHEVIHSTNLPFSCQYCSRSFVTAGKLARHLVAHAGKRVYPCKYCSKSYLLSHHLSRHVRMHKQAAAASFTCSICKDTHQSYDSLVDHSSIHASVSLICPLCKASIADADSLEPHMQAHKESERHACEFCDFIFLSSAHLQKHIEDDHVVDMVPYQNESEYEQGVNKEEEVEEESELMEELLAEMSPSPSPSPTPTKIRKLNPIAKTTQTQDDKTKRESRSKIIKPTPEISPDNRKRARSVHKSPAASSVSPESKRQTRRHDSKERSLKPNDSAKRSTKKIVVEQSRQPSKHRNLKVSSSKSKSPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599057;
90% Identity: iTF_00599057;
80% Identity: -