Basic Information

Insect: Drosophila engyochracea
Gene Symbol: salm
Assembly: GCA_035042385.1
Location: JAWNLK010000105.1:19293100-19300966[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.5e-06 0.00016 21.9 1.7 1 23 369 391 369 391 0.98

2 8 3.5e-05 0.0022 18.2 3.5 1 23 397 419 397 419 0.98

3 8 2.4 1.5e+02 3.0 2.5 5 23 678 696 675 696 0.84

4 8 3.6e-08 2.3e-06 27.6 0.2 1 23 702 724 702 724 0.98

5 8 0.0011 0.068 13.5 0.9 1 23 734 756 734 756 0.98

6 8 0.054 3.4 8.2 0.1 2 23 973 995 973 995 0.96

7 8 1.2e-05 0.00074 19.7 5.0 1 23 1145 1167 1145 1167 0.96

8 8 9.3e-08 5.9e-06 26.3 0.7 1 23 1173 1195 1173 1195 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.5e-06	0.00016	21.9	1.7	1	23	369	391	369	391	0.98
2	8	3.5e-05	0.0022	18.2	3.5	1	23	397	419	397	419	0.98
3	8	2.4	1.5e+02	3.0	2.5	5	23	678	696	675	696	0.84
4	8	3.6e-08	2.3e-06	27.6	0.2	1	23	702	724	702	724	0.98
5	8	0.0011	0.068	13.5	0.9	1	23	734	756	734	756	0.98
6	8	0.054	3.4	8.2	0.1	2	23	973	995	973	995	0.96
7	8	1.2e-05	0.00074	19.7	5.0	1	23	1145	1167	1145	1167	0.96
8	8	9.3e-08	5.9e-06	26.3	0.7	1	23	1173	1195	1173	1195	0.98

Sequence Information

Coding Sequence: ATGTGTTCCATATTTCGCAATCGCATCAATTATCGGGGCACAGGAACGCGCACTGGCACCTCCAATGGCAGTGGAGGAGGTGCAggtggtggtggaggaggcggaggcagcaacagcagcagctcagatCCAATTGGCGAACGGGAGAGTCTCCTGGCCAAGGAACTGAATGCggacagcaataacaatgcgGCGGATGAGACAATCGAGCCGGAAATGGAGatggagctgcagctggagaaggagaaggagaagcaaTCGGAGACATCACTGCCCAGCTCCGATCAGCCAGAGAATAGCAATGAGGCATTGGATCTCTCGGTCATCTCGGGCAATCGGTTGCCCAACAGTGGGCATGTGGCACTAGAAGCTTTACAACATACCAAAGTGGCGGTGGCTCAGTTTGCGGCCACGGCGCTGGCGGCGGCATCCACAGATCCCAGTGATCTGGCCATGGTGCAGTCGACCATCTTCAATGTGCAGCGACAGCATctgatgcagctgcagctcatcCAGCATCTACAGAGTCAATTGAAGCGAGCGGGGGGCGTGGTCGCCGCCCTCAGCCGGCAGGGTCAAAACTATGCCGAGCAGGATGACGATGAAGCGGGAGAGGAGGCCGAAGATGTGGAAGAGTTGGAAGAGGAGCAGCAACTGTCGATGCCATCCAAAGAGCCGTCGCGAGTTAACGGTGAGCGAACCGAATTGGATCATGCAAGGCTGGAGGAGAGTTCAAAGACTGATGACGAGTGCAATAGGCTGGGCGAGAGACCAAGGCGCGCCTTGGCCAGGGAAAGATCGCGGGAGACGACGAAgacggaggcggaggcggaggcggatgCTGAAGCCGAAGCCGAACACGAGCTGGCCGAGAGCGAGTACAAGCCACTGATGTGCGACATTAGCTCCAGTCTGGCGTCCAGCATCATCACCAATCATGATCCGCCGCCGGCGCCCAATGAGCCCAACTGCTTGGAGATGCTGCAGCGTCGCACCGAGGAGGTGCTGGACTCTGCATCGCAGAGTCTACACGCCGCCCAGATGCAGGAGGAGTACTCGGAATATGCCACCAAGGAGGCGCAGAGTCGCGGCGAGATCTTCAAGCATCGCTGCAAATATTGTGGCAAAATCTTCGGCAGCTATTCGGCCCTGCAAATCCATTTGCGTTCGCACACGGGCGAACGACCCTTCCACTGTAATGTTTGCGGCAGCAAGTTCACCACCAAGGGCAATCTCAAGGTGCACTACCAGCGGCACACGCAGATCTTTCCACCCATGCTGATGCCACCCGTGGTCAACGGGGTCAGTGCACCCGAGCAGTTTGCTGCCATTCGACTGCCGTTTGTGACACCACcagcggtggcagcagcagcagcagcagcaccaccaccactggcagcaccactaccaccaccaccacccccacTCCCGCCGCCAAGCAACGAACAGTCAGCGCTGGAACAGCTACAGGAGCCGACAGCTCTGGGACGACTGCAGCAGGCCGAGGATCTGAGCAAGCCACCAGCCACCAGAGAATTGTCGCAATCACCCGAGCAAGTCACGCAACCAGCTCCGTTAACCAAGTCGCTTATCGAGCCACCTGCGTTGGTGTCGCCCGATAAACAGGACCAGGACAAGACGAAGGACAGTCCCAAGCCAACGACACCGCCAACGCCACCAGCTCCCTCGCCAACAACACCAACCACTCCAGCAGCAAGCAATCGTCGCAATGGTAGTGTCCGCAAGCGGCAGACAAGCCAGGCGGGTAGTCCGCCTGGCGAGGAGCATCCTCATGCCGAGCATCACTCGCACCTGGTCAAGTTGGTGCGTCGCTCGTCGGCGAGCCGGGATGGGATGACAGGGATGCCTGGCGGTGGTTTGCCTGGCGAGTATTCGTTGGCGCAGATGGAGCGTATTATTGACAAGTCGTGGGAGGATCTCATTGAGATCGACAAGACGTCGGAGACATcgaagctgcagcagctggtcGATAATATTGAGAACAAGCTGACCGATCCCAATCAGTGCATCTTCTGCCAGAAGGTGATGTCCTGTCGCAGCTCCCTGCAGATGCACATACGCACCCATACCGGGGAGCGACCCTTTCGCTGCAAGATCTGCGGACGCGCCTTCGCCACCAAGGGCAACCTGAAGGCGCACATGAGCATCCACAAGATCAAGCCACCGATGCGCAGCCAGTTCAAGTGTCCCGTATGCCATCAGAAGTTCTCCAACGGCATCATTCTGCAGCAGCACATACGCATCCATACCATGGACGATGGCAGCGCTGGTCATGCTCAGCTGCAGGGGCAGGGTGGCGATGTCGAACGCTTGGGCATCGAGGATCAGAACTCGAACAAATCGATGGGCACCTCAGACACGCTTGACTTCTCGACGACCGTCTCGGATCATTCGGGTCAGCGATCGGAGTCGTCGCAGGGTGGCGACTTCGATGAGTTCATGACCATGGACAGCACCGATGATTCGCGTGACAATTCCAGTGCACTGCTCGACAGGGAGAGGGAGCGAGATAGACGCCTGCCTGGGCACGATGATGAGCGCTCCCGGTCGGACGATGTGGAGGGCAGCGGACGTGAAAGTGCCAGCGGTGAGATGCCCGCCATGGATCTATCATCACCATCGCCATCGGCCACATCGCTGGCACGTCTCTTTGGTGTcggtggcggcggcaacagcggTGCCACGTGCTCAGGCgctggcgttgctgctgctgctgctgctgctgcagccaatTCAGGCGGTTTGCCGATGTTGCATGGCATGCCGATGCCACCGaatctgctgctgatggccGCTGCCAGGGAGGAGATGCATGCGCTGGGCCAGACGCATGCCAAGTTTCCGCTGTTGCCGTTCGGACCGCTCGGATTAATGGGACTGCAGCCGCCCCCAAATGTGTGCAATCTGTGCTTCAAGATGCTGCCCAGCCTGGCCGCCCTCGAGAGCCATCTGCAGAGCGAACATGCCAAAGAAGTGACGGCTCCTTCCGTTCGAGCCCACTGCAACGATGCGTTATCACCCTACGGTGCAAAGCTCACTCTCAATCCAAATCTGTTTGCCAAGAAGCCGAAGCCATCCTCAACGCTGGAGATGGCGCCTGCGGACTCAGTCACGCCATTGTCGGCACCCATTAAAGAGGAGCCCGATTcagatcagcagcagcagcagcagcagcagctgcagctactCGATGAGGGTGGCTGCGATAGTGGCACCAGTAGTGgcacttctgctgctgctgctccggctACTGCTGGATATCAGCATGAGGCTGCCGCCGATGCGGAGCAATCCCTAATGAAGATGCAGTTGCATGCACATCGATTTCCAGCTGGTCCGCTGGACTTTCAGCAGGCATTGATGTCGGCCGGCCCGCCCAGCTCTAGCTTGGATCCGCCGGTGAATAACAAGCACTTTTGTCACGTCTGTCGTCGCAATTTCAGTTCGAGTTCGGCACTGCAGATTCATATGCGCACCCACACCGGAGATAAGCCGTTTCAGTGCAATGTGTGTCAGAAGGCCTTCACCACGAAGGGTAACCTTAAGGTTCACATGGGCACGCATATGTGGACGAATCCGACATCGCGTCGCGGCCGTCGCATGTCCCTGGAGTTGCCGATGCGACCGGGACCTGGCCCGGGCCCAGGCGCCGCACATGGTGTACCAACGGCTGAACAGGAGTTCATGCAGCGACGCCCAGAACTGTTCTTCCCATACTTGCCACCCTTCTTCAACGGAATGCCACCCAAgCCCGGCGAATTGAGTCCTGGCGCTTTTGCCAACATACCTCCACCGCATTTTGCAAATGGAGCCAAGTATCCATATCCACCGGGTCTGCTCAGCTTTCCTGGCTTTCTGGGTGGTGCTGGCGGTCATCACCAGCATCCCTATGGCGGAGTGGAGCGGGGCAACAGCAAGTCACCCACATCGGAGCCGGCACAGAGTCCTGCTTCTCGTGAGGATGACTCGGGTCTCAGTAATAATATCTGGCATCCGCTGAGCAGCATTAAGATGGAGAGCAATCAAAATGAGAGCACTGGCAATCAGAGCGAGCAGGAACaggaaccggaaccggaacaAGAGCAGGATCAGCAGGAGGATAATAAGAGTGTAGGCATCGATGCGGATGGCGAGCCTGATCCGGATGCTGAGGATTCAGCTGAGAAGTAG
Protein Sequence: MCSIFRNRINYRGTGTRTGTSNGSGGGAGGGGGGGGSNSSSSDPIGERESLLAKELNADSNNNAADETIEPEMEMELQLEKEKEKQSETSLPSSDQPENSNEALDLSVISGNRLPNSGHVALEALQHTKVAVAQFAATALAAASTDPSDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRQGQNYAEQDDDEAGEEAEDVEELEEEQQLSMPSKEPSRVNGERTELDHARLEESSKTDDECNRLGERPRRALARERSRETTKTEAEAEADAEAEAEHELAESEYKPLMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYATKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLMPPVVNGVSAPEQFAAIRLPFVTPPAVAAAAAAAPPPLAAPLPPPPPPLPPPSNEQSALEQLQEPTALGRLQQAEDLSKPPATRELSQSPEQVTQPAPLTKSLIEPPALVSPDKQDQDKTKDSPKPTTPPTPPAPSPTTPTTPAASNRRNGSVRKRQTSQAGSPPGEEHPHAEHHSHLVKLVRRSSASRDGMTGMPGGGLPGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSAGHAQLQGQGGDVERLGIEDQNSNKSMGTSDTLDFSTTVSDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSALLDRERERDRRLPGHDDERSRSDDVEGSGRESASGEMPAMDLSSPSPSATSLARLFGVGGGGNSGATCSGAGVAAAAAAAAANSGGLPMLHGMPMPPNLLLMAAAREEMHALGQTHAKFPLLPFGPLGLMGLQPPPNVCNLCFKMLPSLAALESHLQSEHAKEVTAPSVRAHCNDALSPYGAKLTLNPNLFAKKPKPSSTLEMAPADSVTPLSAPIKEEPDSDQQQQQQQQLQLLDEGGCDSGTSSGTSAAAAPATAGYQHEAAADAEQSLMKMQLHAHRFPAGPLDFQQALMSAGPPSSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPGPGPGAAHGVPTAEQEFMQRRPELFFPYLPPFFNGMPPKPGELSPGAFANIPPPHFANGAKYPYPPGLLSFPGFLGGAGGHHQHPYGGVERGNSKSPTSEPAQSPASREDDSGLSNNIWHPLSSIKMESNQNESTGNQSEQEQEPEPEQEQDQQEDNKSVGIDADGEPDPDAEDSAEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00525326;
90% Identity: iTF_00514342;
80% Identity: -