Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000105.1:16353365-16357342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00015 0.0096 16.2 3.4 1 23 286 308 286 308 0.99

2 8 2.1e-06 0.00014 22.0 0.8 1 23 313 335 313 335 0.98

3 8 1.1e-07 6.7e-06 26.1 0.2 2 23 344 365 344 365 0.97

4 8 6.3e-07 4e-05 23.7 0.3 1 23 371 393 371 393 0.98

5 8 7.9e-08 5e-06 26.6 3.9 1 23 399 421 399 421 0.98

6 8 2.9e-07 1.8e-05 24.8 1.9 1 23 427 449 427 449 0.98

7 8 6.3e-06 0.0004 20.6 5.1 1 23 455 477 455 477 0.98

8 8 0.00021 0.013 15.8 0.5 1 21 483 505 483 506 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00015	0.0096	16.2	3.4	1	23	286	308	286	308	0.99
2	8	2.1e-06	0.00014	22.0	0.8	1	23	313	335	313	335	0.98
3	8	1.1e-07	6.7e-06	26.1	0.2	2	23	344	365	344	365	0.97
4	8	6.3e-07	4e-05	23.7	0.3	1	23	371	393	371	393	0.98
5	8	7.9e-08	5e-06	26.6	3.9	1	23	399	421	399	421	0.98
6	8	2.9e-07	1.8e-05	24.8	1.9	1	23	427	449	427	449	0.98
7	8	6.3e-06	0.0004	20.6	5.1	1	23	455	477	455	477	0.98
8	8	0.00021	0.013	15.8	0.5	1	21	483	505	483	506	0.94

Sequence Information

Coding Sequence: ATGAGCAACGCACCCGCAACGcacacaacaagaacaacacgaagaagaagcagcagtgGCATGGGCTTTAAGCATGCGATGCTGCAACGCAGCTACGATCTCGCCGCATCTCCTGCCCCAGCAGAGGCGCCTCAGCAAGTTACGGATTTTAGCATCAGCCGCATTCTGGGCAACGTTGGCAAGGATACTCCAGTGAAGAAGAAGACAGCAgcgagtgctgctgctggcaacattCTCGATCTCTCGAAGAGCAGTCAACAGCAACCTCAGGCAGTGCAGCCCTTTCAAAATGCATCGGCAAGTTATGGCTATGCCATGTTGCCACCGGATTTGCTGGCCATGGCCAGTGCAACCAAATTCTATGCACAGTTCTTTCCACACTTGCTGCCTGCCtatgcggcagcagcagctgccgccggcTTCACAACGCCACCCACGTCGCCCTatcagcaacaccaacagcagcagcagcaccagcagcatcaccatcagcagcagaagcgttACTTTGCCCCTTATGTGATCAACGGACAAAGTCCGACACGGGCCAAACCGAGTGCACCCAGTGTCTGCACTCGTGCGGATTGCGTGGAATGCCTGGACTACTATAGACAATTTGGAGCGGGCTACAAGCCGACGCCATTGATTTCGCCGGCGGCTTCTTCGGTCAGCAGTGCGAGCAGCTCGAGGCTCGGCCGTGCagacagcagcaccaccaacatTTCATTCACCACGGTGACCAATCTGAATCTGAGCAcgaccgcaacaacaacaatgacatcagcaacaacaacaccagcattGCCCAATTTagttgccaacaacaacaacacaacgaCGGCTGAGGAGATCAGCTACAAATGTCACATCTGCGACAAGGTCTTTGGATGCTCCGAAACACTGCAGGCGCACGAGAAGACGCACAAATCACCGCGCTACGAGTGCTCAGATTGTGGCAAAGGATTCTCGCAGCTGCGCAACTATAAATATCACCTGTCTGTGCATCGTGGCACGAAAGAGTTTGCTGCCGAGTGTCCGGAGTGCGGCAAGACCTTCAACGATAAGGGCTATCTGAGCAGTCACATGAAGATCCACCGCAACCGGAAGGAGTACGAGTGTCCCTACTGTCCTAAGTCTTTCAATCAGCGTGTCGCCTTCAACATGCACGTACGCATCCACACGGGCGTCAAGCCGCACAAGTGTGCCGAATGCGGCAAGCGATTCTCTCGCAAGATGCTGCTCAAGCAGCACATGCGCACGCACAGCGGCGAGAAGCCGTATCAGTGCTCTGTTTGTGGCAAGTCCTTTGCGGATCGCAGCAATATGACGCTCCATCATCGGCTGCACTCGGGCATCAAGCCATTTAGCTGCCCGCTGTGCCCCAAGGCATTCACCAAGAAGCATCACCTGAAGACGCATCTCAATTATCACACCGGCTGCAAGCCGTACGTCTGTCCACATCCAAATTGCAATCAGGCCTTTACCCAGTCCAGCAATATGCGCACCCATGCCAAGAAGTGCCAATACCGACCGCTAGACGGCGCTCAGCCATTCCCGATGccacacaagcagcagcagctgcagcaaccacaacagcagcaacaatcgctgGCGTTGCCAACAGCTGCAAGTTTTGTTATGCCACCGGCAACATTTGTCCCTGCTGCATCCGCAATCACCTTTCCGCCGGCCCAGCAAACGCTCCTCAGCAATTTGAGAACATTCCAAGCGATCTGA
Protein Sequence: MSNAPATHTTRTTRRRSSSGMGFKHAMLQRSYDLAASPAPAEAPQQVTDFSISRILGNVGKDTPVKKKTAASAAAGNILDLSKSSQQQPQAVQPFQNASASYGYAMLPPDLLAMASATKFYAQFFPHLLPAYAAAAAAAGFTTPPTSPYQQHQQQQQHQQHHHQQQKRYFAPYVINGQSPTRAKPSAPSVCTRADCVECLDYYRQFGAGYKPTPLISPAASSVSSASSSRLGRADSSTTNISFTTVTNLNLSTTATTTMTSATTTPALPNLVANNNNTTTAEEISYKCHICDKVFGCSETLQAHEKTHKSPRYECSDCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHMKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCAECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKCQYRPLDGAQPFPMPHKQQQLQQPQQQQQSLALPTAASFVMPPATFVPAASAITFPPAQQTLLSNLRTFQAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499718;
90% Identity: iTF_00596074;
80% Identity: -