Basic Information

Insect: Drosophila emarginata
Gene Symbol: PRDM1
Assembly: GCA_037075365.1
Location: JBAMCD010000296.1:2897781-2902429[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.1e-05 0.0027 18.4 2.5 1 23 891 913 891 913 0.99

2 5 9.3e-06 0.00081 20.1 5.1 1 23 919 941 919 941 0.98

3 5 1.9e-06 0.00017 22.2 4.3 1 23 947 969 947 969 0.98

4 5 0.00064 0.056 14.3 2.4 1 23 975 997 975 997 0.97

5 5 0.00011 0.0096 16.7 0.1 1 22 1003 1024 1003 1024 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.1e-05	0.0027	18.4	2.5	1	23	891	913	891	913	0.99
2	5	9.3e-06	0.00081	20.1	5.1	1	23	919	941	919	941	0.98
3	5	1.9e-06	0.00017	22.2	4.3	1	23	947	969	947	969	0.98
4	5	0.00064	0.056	14.3	2.4	1	23	975	997	975	997	0.97
5	5	0.00011	0.0096	16.7	0.1	1	22	1003	1024	1003	1024	0.96

Sequence Information

Coding Sequence: atgcatGGACATCATCAGAAtacgcagcaacagcagccacagagCCACAATATGAAGCCTGCAGCTATCAATTTACCCCatccacaacagcagcaacagcagcagcaacagccacatCAGAATCCAAATCCTCAACAACCAGCACATCCACATCCAACTACACATCCACCTCCTCAACAGCATATTCCCCATTCCcatccgcatccgcatccACATCCTCATCACcatcatcctcctcctccgcatcatcaacatcaacatcagcatcatcatcatcataaacTCACACGACGTGGACGCAGTCGTAGTCGTAGCCCAACACCAGATGGTACACAGGATTATGATGTTACGCGCATGCGTGAGGAGGATTTTGAACGTTTGGCTGTCTATCTGGTACCCGATGTTCAGGCTGAACGTGGTTTGCCCAATCGGGCAGATAAAACGCTGCCGCGCAGTTTAACACTTAAATCATCGATGGTCTACTCAACGCCAAATGATAAGaCTGAAGGAGTTTGGAGCGGCGGTGTCATACCGCGCGGTACACGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGCTATTTTTGGCGGgTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGAtgactattattatttagatgGTTCAGATCGTTCACAATCAAATTGGATGCGTTATGTGGCGTCAGCTTATAGTTTATCGGTGATGAATTTGGTTGCCTGTCAGCATATGGAGAACATCTATTTCTATACCACACGCGACATAATGCCCAATGAAGAGCTAATGGTTTGGTATTGCAAGGACTTTGCCACTCGTCTCGGCTACGATGTGGATCCAGAGCGTACAATCTTTGGTGCCTGCAAGCAGGTTGAAGGCGATGAAGCCGACAGAGAAGAGGATGAAGAATGCATGGATATGGTCGAGGATGAGGAAGATGCGGCAGGTTTAGCTGCAGGAAAGAAATCACATTACACAATGCCAGCGCCAGCAGAGATACCCGCCGAAGTGGCTGTGAGTCATATAACCTATGTGATGGGTCTCCATCTGCCAGCTAGTGCTGCATCAGtaccagcaacagcaccaccaccaccaccagcagcgCCATCCCATGCAGGGGGAGCAGGGGCAAGCCAAGCAACGGCTTCTGGTTGTTGCACTCATGTGAGCACGACAACATCATCGACAAATCTTCATCCTCATATACAGCATAGTCGGCATGCTTCGGTCATTATGGGTGGACAGGATCGTTCACCTTTGAATCCTAGTGACAAGGAGGAGGCTGCTCGTTCGCCGCTCTCAGCGATGATGGCCCAAGATGGTAGCGTTAGATCAGTCCGTTCTGATGAGGGTTATCATAGCAATGAGTGTCATGAAGATGGTCTGACTCCACCGGAGGATTCGAGCGATAGTGAGAGTGAACATAATTATGTTTTAGATTGCTCCAAAAAGGCCATTGCACCCAAGGAGACTGTCATTGCCCAGGCGCAAAAATCCGTCAATGGGAATAAATCACCGCAAACCGTGGTAAAAAGTCCCAGTCCTCCACTAATGGCGCAACCGCAGAAGCATCAACCGGATGCGGATAAAAATGAGTATCGTAAATTTAAAGTGAAGATGcctttaaaatatgaaatcaaaaataaaacgatcAATTGTGTAAAACAAGAGCCCATTAAGGAAGTGGAAGAGTCACCACACATGGTAAACGAAGATGAGGATGAAGAGAGAATGCATGCCACTTCGACTTTGGCTGAGGACCGTGAATTAACCCAACAGCAGCCGGCCTCGTCGACGGTCATTGTGCTAGAACAATCAAGAACCATAGTGCCCCTAACAAAACCCTATTATGAAAGTGATACGCCTGCCCTACGTTTCAGTCAACCATCGTCCAGCATATTGGAGACGATCCTGACGAGTCAGCATCGTTTGGAAGCAGCTGCTCGTCAAGCAAATGCAGCTACACCTCCACCCACATCGCCGACAGAGATGGCCTACAGCTATAAGAAATCTCAGCGGTATGGTAATGCTGTGAGTCCCGATTCCAGTTCAAATTTGGGCCAGAATGTAGATATACCCAATGAACAGGAGACTCTAACCAGGTCAACTCTTATCAAAGGGGAATGCTCACCACCGCCAGCTCAACATCATttgcagcatcatcatcatcatcatcacaatGTCATTTACTCACCCAGACATCCTGCCTACCTGAATGAGGGAAGAGTCGTCGATGAAAATCATCTTCATAGTGGTGGCTCTCCTGGCAGCTATCCACCCTACCCACACTATGGCTCTGGTTCGGCAGCCACATCCACCTTCCATTCACCTCCCCATAGTTCGCATTCGCCCTTCGATCGGCAATCGAATGCATCGAGTGGTGCCGGTTCAGCATCGAATCTTCATCTGCTGCAGAGTAGCTCCCAAATGCTAAATCATCCACTAATGCAGCCACTAACACCATTGCAGCGATTATCACCGCTAAGGATTTCACCGCCCAGCAGTCTCAGTCCTGATGGCAATTCTTGTCCACGCAGCGGCAGTCCCCTCAGTCCCAATTCATTGGCCTCGCGGGGCTATCGCTCCCTACCATATCCCTTAAAGAAAAAGGATGGCAAAATGCACTATGAATGCAATGTCTGCTGCAAAACCTTCGGCCAATTGAGTAACCTCAAGGTACATCTACGCACCCATTCGGGGGAGCGTCCATTCAAGTGCAATGTCTGCACAAAGAGTTTCACACAGTTGGCCCATCTACAGAAACATCATTTGGTTCACACCGGCGAGAAACCCCACCAGTGTGATATATGCAAGAAACGTTTCTCTAGCACTTCGAATTTGAAAACCCATCTGAGATTGCATAGTGGCCAGAAGCCATATGCCTGCGATCTGTGCCCGCAGAAATTTACGCAATTTGTCCATTTAAAATTGCACAAGAGATTGCACACAAACGATCGGCCCTATGTGTGCCAGGGATgcgataagaaatatattagcGCATCTGGATTAAGAACACATTGGAAGACAACCAGCTGTAAGCCAAATAATTTGGAAGAAGAATTGGCCATGGCAGCGGCAGCCACATCAGAGTGTTTAgaTAAAGATCTCCCTGAACCTGAGACATATgagcaattgcaacaacatATGCAACAGCCGGGACATCATGCCCATCCAAGTCTAAGGCATTCACCGCCCAGACTTATACCCCTCGGGGCccaccatcagcagcagcagcaacatcatcaacagcaatcGCTTCCTCCCCCATCGCCGCAGCATCTAATGATGCCACAGCATGGTGCACCCATGTTGCTGACCACAGCTCTGCCTCCACTATCTCcgcatcatcctcatcatccaacacatcagcagcagcagcagcaacagcaacagcaacagcaacaacaacaacagcagcagcaacaacatcatcaccagcatcagcagcaggcGCAATCAACTCCTTCTGCACCACAGCAGCATTTGCCTTTGAAAACGTCCCTTAAATCGCTGCAGGAATCATCATCTTACAGTCTGCACAATCAACCGCCGCCACATCTTCAGGCTCAGGAGAGTCGGCCATCGGTCATTGAGTCCTCCAATCAACCCATGATCATTGAATGCACGTAG
Protein Sequence: MHGHHQNTQQQQPQSHNMKPAAINLPHPQQQQQQQQQPHQNPNPQQPAHPHPTTHPPPQQHIPHSHPHPHPHPHHHHPPPPHHQHQHQHHHHHKLTRRGRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNDKTEGVWSGGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHMENIYFYTTRDIMPNEELMVWYCKDFATRLGYDVDPERTIFGACKQVEGDEADREEDEECMDMVEDEEDAAGLAAGKKSHYTMPAPAEIPAEVAVSHITYVMGLHLPASAASVPATAPPPPPAAPSHAGGAGASQATASGCCTHVSTTTSSTNLHPHIQHSRHASVIMGGQDRSPLNPSDKEEAARSPLSAMMAQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKSVNGNKSPQTVVKSPSPPLMAQPQKHQPDADKNEYRKFKVKMPLKYEIKNKTINCVKQEPIKEVEESPHMVNEDEDEERMHATSTLAEDRELTQQQPASSTVIVLEQSRTIVPLTKPYYESDTPALRFSQPSSSILETILTSQHRLEAAARQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQNVDIPNEQETLTRSTLIKGECSPPPAQHHLQHHHHHHHNVIYSPRHPAYLNEGRVVDENHLHSGGSPGSYPPYPHYGSGSAATSTFHSPPHSSHSPFDRQSNASSGAGSASNLHLLQSSSQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPETYEQLQQHMQQPGHHAHPSLRHSPPRLIPLGAHHQQQQQHHQQQSLPPPSPQHLMMPQHGAPMLLTTALPPLSPHHPHHPTHQQQQQQQQQQQQQQQQQQQQHHHQHQQQAQSTPSAPQQHLPLKTSLKSLQESSSYSLHNQPPPHLQAQESRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618673;
90% Identity: iTF_00484057; iTF_00556159;
80% Identity: -