Dema016400.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila emarginata
Gene Symbol
-
Assembly
GCA_037075365.1
Location
JBAMCD010000283.1:3883447-3886607[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 2.6 2.3e+02 2.9 3.4 3 23 273 294 271 294 0.92
2 8 0.0014 0.12 13.2 4.8 1 23 628 650 628 650 0.97
3 8 0.00061 0.053 14.4 0.2 1 23 656 678 656 678 0.98
4 8 0.00057 0.05 14.4 0.9 1 23 684 706 684 706 0.98
5 8 4.7e-07 4.1e-05 24.2 0.2 1 23 712 734 712 734 0.99
6 8 3.2e-05 0.0028 18.4 0.3 3 23 742 762 740 762 0.98
7 8 2.9e-06 0.00026 21.7 0.6 2 23 769 790 768 790 0.97
8 8 6e-05 0.0052 17.5 1.2 1 23 796 819 796 819 0.97

Sequence Information

Coding Sequence
atgacaaGTGTGTCCGTggcaaagcaacaacaaagaaaagcCACAGCGAACGTAAATGAAGAAGACTCACCAGCAGTAGCAGCGGCGTCAGCGGCTGCAGCAGCAGGGGAGGATTCTGAATTAGAATTGGATATAgacgaagatgatgatgatgaagaggatgatgaagaagaggaTCTGGTACTGCAAATTGATAGTGAAGATGAGGCCGAATTGGAGGCCCAGCGTATACGCTTAGATGAGGCCAAAGAAGCAGCCAAAGTAGCGACAGCAAAAGCTAAAGCAGTAGCTGTAgcagcgacagcagcagcggcagcagcagcagcagtagcagcggcaacggcaacaacaacaacaaagtcgCAGGTCAGTAACGGTAAAGAACAAGCCCCCATTCACGCCGCCGCCGCAACAGCCGCTAAACGTAAACCTCGTGGCCGTCCGCCCATGCGCCGAAACTCTTCTAGCTCCACTTGCTCCACCTCCACAGTGACTTCCGATTCCACAGTTTCGTCTACCTCCTCAACAAGTGCTGTAGCTGGCCAAATTTTGGCCGATGAAAAATCACATTGCCTGATTTACAGTTGCTCACGCTGCGCTGGGCACTACGAGGATGGGTTCAAACTTTCTCAACATTTCCAACGGGATCATTCTACTCCTCCTGCCCATCCCCCTCAATTGGCAGGCAGCAAAAAATCTCAGGCTAAAGGCAAGAAAAAATCGGAAAAAAATGAACCAGAATTAGATCCATTGCCAGTAACTGCTCAACGAGCTTGTGCCAAATTGCTCGTGCAAGGGGAATCTCTGCTCCACTTGTGCCTCTCCTGCAATTCACAGTTTGTGGAACAGAAACATCTGAGCCAGCATCTCAATGAACAACATGGATACTTTAAGCTGCTGGTTCCCAAGGAGGAGCCGGTTGAGTTGCCACCAATGGCCATGGTGACTATTCCCAGGGCTATTCAGCCTCAGCAGCAGCATGAGCAGGAGCTGCAATTGCCCATACCCGCCGCACCAGAAACACCACCACCCGAACAGGATGGCAAGGATCAGCAGCAGGTTGAAGTTGTTGCTGATGGCTCTAGCAATGATAAAGATGATCTCGAAATGTTGGATTCCATGGTGGCCGAGATAACTGAAGCCCCAAAAAGTCCAAAAGTCAATAAGATGATTATTAAACTGCCAATGGGAAACAAACGTGGCAGGAAGCGGACCAGAAAAGAGGACGAAGAGCcgaaagtaaagaaaaaacagcGGGGTCAGGAGGATAAGTCAAAGGATCATGTTGAACAGCCGGAGGTAAAGCAGAATAAACGCAAACTGGCAGCTAAGACCAAGGAGGATTTGAAAAAGCCAGAGGTGGAACCGTCCACTAAAGAGTTGGAGAACGAGAAGGAGTCAAAGGAGGACCGCACAAATAAAAAGCAGGAAACAAATGAACAGCGTGGCAAAGTCAAGAAATTGACAAAGAAGAAGGcacaacaaaatgaattgaCAGAAAAGGAGTCGGAAAAACCAgtggagaaagaaaaaccagaTGATAACGTGGAGGAGCAAAAGGAGCAGCAACCAAAAGAGGATGCCACCGGGGTAGGCAAACGGAAACGTACGAGAAAGATATCAGCAGCCACAATCTCTGATGAATCCAAGGAAATCAAGGAGGAGTCAGAGGAGCCCATTGAACAACGACGCATGCGTAAAACTCGTCAACCGGTGGATTACGTTGATATTAAGGATGAAGAAGAcgatgaggaggaggaggaggacgATGAAGATGACGCCGAGCCAATTCTATCAAATAATAGCTCCGCGACAGATAGCACCGCCATAGTGAAACGTGAATCTCTTGAGGAATCGTACCGTAATGGTGGCCACACCATACACACATGCAACTTTTGCGGAAAAACATTTCAACGTTTCTCCCGAATGCAGGATCATCTGCGTCTCCATACGGGCGAGAAGCCCTATGTTTGTGGCCAATGCGGTCGAGCCTTTCGCCTGAAAATGCGTCTGGCCGAGCATCAGTTGCGCCATCGAACCGAAAAGGCATTCAAATGTGAGATATGCTCCATGCCATTGGCCACAAAGCAGGATCTATCATTGCATATGCGTCATCACAAGAACGATCGCCGCTACAAGTGTGAGAGATGCGGCAAAGGCTTTGTCCGAAGCTCAGATCTGTCCATCCACGTGCGCATACATACCGGAGAGAAGCCATTTGGTTGTGATCTATGTGGCAAGGCATTTAGGGCACGCCAAAATCTCGTTGTGCATCGTCGAACCCATTTGGGCGACAAGCCCATACAGTGTGAATTGTGTGACAAGCGATTCGCTAGAAAGATCGACATGCGTGTCCATATGCGAAGACATACTGGTGAAAAACCGTACAATTGCGAGTCGTGCCAGCGTGGCTACTCATCACGGGTGAATCTACAACGTCACCAGCAAAAGGAACATAAATCTGGCTCCTCCTCTTCCAACAAAAAGCCAGTAGATTCAGAATCCGAGCCAACAACAGTAAAAGCAACTGCCTCAGTGGATGTAACGCTTCCGACACGTCGCCCTAGACGTGagaaactacaacaaaaaatagctgctcaagaaaaactattaaatgaaCTCAAGCGCAGCTTGAGTGCCTTGCCTGAAATAGCCGAGGAATCTGCATCATCGTCGCCATCATCACGGGGACCACCAGCAAATAAATTGGATCTTGTCGAATTGCCAGCTGATGCCGGAGCCGGCTGTGGCAACCAATCGACAATCAGTCAAGTGTCGGTAACAGTTTCTATGCAGATGGCCAATCCAAAAGCAGTTCAAGACGATGAGGACGAAGAAACCACACCCGAGAAGGAGAACGCTTTGTTGTCCAGCAGTGCGCCGGCAGTTGACAAGACAAAGACGAATCGTAAAATAACAAGCTATTTTACAGTTGTCGGCCAACAGGCAACggaattataa
Protein Sequence
MTSVSVAKQQQRKATANVNEEDSPAVAAASAAAAAGEDSELELDIDEDDDDEEDDEEEDLVLQIDSEDEAELEAQRIRLDEAKEAAKVATAKAKAVAVAATAAAAAAAAVAAATATTTTKSQVSNGKEQAPIHAAAATAAKRKPRGRPPMRRNSSSSTCSTSTVTSDSTVSSTSSTSAVAGQILADEKSHCLIYSCSRCAGHYEDGFKLSQHFQRDHSTPPAHPPQLAGSKKSQAKGKKKSEKNEPELDPLPVTAQRACAKLLVQGESLLHLCLSCNSQFVEQKHLSQHLNEQHGYFKLLVPKEEPVELPPMAMVTIPRAIQPQQQHEQELQLPIPAAPETPPPEQDGKDQQQVEVVADGSSNDKDDLEMLDSMVAEITEAPKSPKVNKMIIKLPMGNKRGRKRTRKEDEEPKVKKKQRGQEDKSKDHVEQPEVKQNKRKLAAKTKEDLKKPEVEPSTKELENEKESKEDRTNKKQETNEQRGKVKKLTKKKAQQNELTEKESEKPVEKEKPDDNVEEQKEQQPKEDATGVGKRKRTRKISAATISDESKEIKEESEEPIEQRRMRKTRQPVDYVDIKDEEDDEEEEEDDEDDAEPILSNNSSATDSTAIVKRESLEESYRNGGHTIHTCNFCGKTFQRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLAEHQLRHRTEKAFKCEICSMPLATKQDLSLHMRHHKNDRRYKCERCGKGFVRSSDLSIHVRIHTGEKPFGCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCESCQRGYSSRVNLQRHQQKEHKSGSSSSNKKPVDSESEPTTVKATASVDVTLPTRRPRREKLQQKIAAQEKLLNELKRSLSALPEIAEESASSSPSSRGPPANKLDLVELPADAGAGCGNQSTISQVSVTVSMQMANPKAVQDDEDEETTPEKENALLSSSAPAVDKTKTNRKITSYFTVVGQQATEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00577987;
90% Identity
-
80% Identity
-