Basic Information

Insect: Drosophila emarginata
Gene Symbol: GFI1
Assembly: GCA_037075365.1
Location: JBAMCD010000119.1:2064388-2085199[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0002 0.018 15.9 3.6 1 23 489 512 489 513 0.96

2 6 0.00031 0.027 15.3 0.5 1 23 518 540 518 540 0.97

3 6 3.6e-07 3.1e-05 24.5 1.9 1 23 546 568 546 568 0.98

4 6 1.8e-05 0.0015 19.2 4.2 1 23 574 596 574 596 0.97

5 6 2.2e-07 1.9e-05 25.2 2.5 1 23 602 624 602 624 0.98

6 6 4.4e-05 0.0038 18.0 5.0 1 23 630 653 630 653 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0002	0.018	15.9	3.6	1	23	489	512	489	513	0.96
2	6	0.00031	0.027	15.3	0.5	1	23	518	540	518	540	0.97
3	6	3.6e-07	3.1e-05	24.5	1.9	1	23	546	568	546	568	0.98
4	6	1.8e-05	0.0015	19.2	4.2	1	23	574	596	574	596	0.97
5	6	2.2e-07	1.9e-05	25.2	2.5	1	23	602	624	602	624	0.98
6	6	4.4e-05	0.0038	18.0	5.0	1	23	630	653	630	653	0.97

Sequence Information

Coding Sequence: ATGGACGTGGCCAAATTGCAAGCTAATCCCGGGCAGCATCTATTGCATCCAGCCGCCTCAGCAGCTCCGCCCGCCCATCAGCATCATTTGCCTTTGGACTACAGTTTGGGGAACTTTAAGCCCGCCATTGCAAGTGATTTTCCGGGACCATTTGTTACCAGTCCCCAGCACCAACAATCTTCCACGTCCTCATCATCCGCATCGTCTACGTCATCCACTGTTTCATCATCGCTCCAGGTGCGTGATCTCAGTGCATTAACCAGCATGGCCACGATACCATCGCCTACACAGCTGTTGCATCAACGCATGCAGCAGGCTCAGGTCACAGTGGATCAACACCAGCCACATAATCCACATCCTCATATGCCGCCGGCTTCGACATCGCCTCATGAATATGCACCCATGTCTGCCTTTAAAGCGGTGCTACCAAAGAAGCGGAATGCCGACGATTCTCTCGCCTTTAGTATAAGCAGACTGGTCAAGACTGAACACCTGACAGCCATTGCAGCAGCGGCTGGAATAAAGCCACTCCCTCCCCTACAGACATTATCATCTCTACCACCGGCTGAGGAGGATAATAACAATTCCATTTCCATGTTGAGcaaaaatcatcatcatcaactgcaacaacaacttcaGCGTTCCACCTCTAAGCCGTATATCATCAGTGCAAGTGAGCAACTGCGTCAGTCGCGCTCCCGTTCCCGCTCTCGATCCCGTAGCCCTTCGCATAGTTCTTCCCAAATCGATATGGATGATGCCTCCGATTCTCATCACTCGCATCGTTCGCTGCACTCCCGCTCCAGGTCACATTCCCATTCGAGTAACTCATCTGTGGAACTTGAAGTGGACTCACCACCAGGAAGTCCAAGTGTTAGCTCACCCAGTGCCGTCTCTGCCTCTGAGCTTCTAATCACGGCCACCAATAGTGGCATTAGCTCGAAGAAATCCGATCTGTTCTCCGTATCCGCATTGTTGCGCCGCGATGAACCCGCCCAAAGACGGGTGCCGCAACGGAGTCCCATTCTTGGATTGCCTACATCAAATTCTGCTTTAACAATGCCCACTAATCCCTTAGAGGCTATGCGACAAAGTTACCCGCCTAACTACGATGCGGCCATGTTCCCGAGGCAGCTGTTTCCACCGACATTGCCCTTCTTTGCCGCCATTGCCTTGCATCAGGgacaacagcatcaacagcatcaAACCGGATTGGGAGCTGGCTACCATCCGGAATCGCAGGAAAATCTCTTCCGTTTACGCAGCCTCATGGTGCCACTTCAGTCTGCTGGACAAAATGGCTCCagtgcggctgctgctgctgccgccgctgctgcagcagctgtgGGCGTTGGTGTGGGTGTGCCACCCAATGGTGGGCATTTGGGTCTGCCACATTCGTCTCACCTGCATTTTCACCATATAGCCGCTAAATGGCCAGGGCTGCATCAATTTAGCGACCTGTACTCATGCATGAAGTGCGAGAAGATGTTCTCAACACCACACGGACTCGAGGTGCATTCCCGGCGCACCCATCATGGCAAGAAACCATATGCCTGTGAGCTGTGTAACAAAACCTTCGGCCATGAGGTCAGCCTCAGCCAGCACAGGGCGGTACACAACGTGGAAAAGGTCTTCGAGTGTAAACAGTGTGGCAAACGCTTTAAGCGCTCCAGCactctatccacccatctgcTTATCCACAGCGACACGAGGCCTTATCCCTGCAGCTATTGCGGCAAGCGATTCCATCAAAAGAGTGATATGAAGAAACACACCTACATACACACAGgTGAAAAACCGCACAAATGTCAGGTGTGTGGCAAGGCATTTAGTCAGAGCTCCAACCTGATTACACACTCCCGCAAACACACCGGCTATAAGCCCTTCTCCTGCAAACTTTGTCACAAATCTTTCCAAAGGAAGGTGGACCTACGTCGTCACAAGGAGACTCAGCATACAGATCTTCGTGTCCATTTGGGAAAAGTTGACTTCATGTctgcggcagcagcagcagctgccgttGAACTAGGTGGAgcggctgcagcagcagcagcagcggccgCAGGCGGACCAGGAGGAGCAGGATCAAATACCACTGGTTTgcaaccaacagcaacaacgggAAGTCATCAAATGCAGGCCAGTTCTGGGTTAACCACCAGTTCGGCTAACGTTGGTGGTCAACCGCAGTTGACCTCACAGTTGAATTGCCAGAAGGTCTCATTGTTGGTATAA
Protein Sequence: MDVAKLQANPGQHLLHPAASAAPPAHQHHLPLDYSLGNFKPAIASDFPGPFVTSPQHQQSSTSSSSASSTSSTVSSSLQVRDLSALTSMATIPSPTQLLHQRMQQAQVTVDQHQPHNPHPHMPPASTSPHEYAPMSAFKAVLPKKRNADDSLAFSISRLVKTEHLTAIAAAAGIKPLPPLQTLSSLPPAEEDNNNSISMLSKNHHHQLQQQLQRSTSKPYIISASEQLRQSRSRSRSRSRSPSHSSSQIDMDDASDSHHSHRSLHSRSRSHSHSSNSSVELEVDSPPGSPSVSSPSAVSASELLITATNSGISSKKSDLFSVSALLRRDEPAQRRVPQRSPILGLPTSNSALTMPTNPLEAMRQSYPPNYDAAMFPRQLFPPTLPFFAAIALHQGQQHQQHQTGLGAGYHPESQENLFRLRSLMVPLQSAGQNGSSAAAAAAAAAAAAVGVGVGVPPNGGHLGLPHSSHLHFHHIAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCSYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAAVELGGAAAAAAAAAAGGPGGAGSNTTGLQPTATTGSHQMQASSGLTTSSANVGGQPQLTSQLNCQKVSLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523990;
90% Identity: iTF_00556110; iTF_00600597; iTF_00604332; iTF_00577983; iTF_00483912;
80% Identity: -